Abstract: The present invention relates to compounds of Formula (I) along with processes for their preparation that are useful for treating, preventing and/or managing the diseases, disorders, syndromes or conditions associated with the modulation of CRAC. The invention further relates to methods of treating, preventing managing and/or lessening the diseases, disorders, syndromes or conditions associated with the modulation of CRAC of Formula (I).

Abstract: The invention relates to compounds of Formula (I) and their pharmaceutically acceptable salts, wherein the substituents are as described herein, and their use in medicine for the treatment of diseases, disorders associated with the modulation of calcium release-activated calcium (CRAC) channel. The invention also relates to pharmaceutical compositions containing such compounds in treating diseases disorders associated with calcium release-activated calcium (CRAC) channel modulators.

Abstract: A dynamic spectrum arbitrage (DSA) system may include a dynamic spectrum policy controller (DPC) and a dynamic spectrum controller (DSC) that together dynamically manage the allocation and use of resources (e.g., spectrum resources) across different networks. The DPC and DSC may store DSC context information, and use this information to perform various DSA operations. For example, the DSC may determine whether there is bandwidth available for allocation within cells in a first telecommunication network, generate a resource register request message that identifies the amount of bandwidth that is available, and send the generated resource register request message to the DPC using a DSAAP component/protocol. The DSC may receive the resource register response message and a bid success message via the DSAAP, and send a resources allocated message to the DPC via the DSAAP to commit the requested amount of bandwidth for use by the second telecommunication network.

Abstract: A dynamic spectrum arbitrage (DSA) system includes a dynamic spectrum policy controller (DPC) and a dynamic spectrum controller (DSC) that together dynamically manage the allocation and use of resources across different networks. The DSC component may be configured to receive notice that an eNodeB is congested, identify a geographic boundary area for a bid serviced by the congested eNodeB, generate a list of eligible active wireless devices that are inside the geographic boundary area, determine an available resource of target a eNodeB that services the identified geographic boundary area, select for handin to the target eNodeB wireless devices from the received list of eligible active devices, and send a handin initiate communication message to the target eNodeB servicing the wireless devices that are selected for handin.

Abstract: The present invention relates to compounds of Formula (I), along with processes for their preparation that are useful for treating, preventing and/or managing the diseases, disorders, syndromes or conditions associated with the modulation of CRAC. The invention further relates to methods of treating, preventing managing and/or lessening the diseases, disorders, syndromes or conditions associated with the modulation of CRAC of Formula (I).

Abstract: The invention relates to compounds of Formula (I) and their pharmaceutically acceptable salts, wherein the substituents are as described herein, and their use in medicine for the treatment of diseases, disorders associated with the modulation of calcium release-activated calcium (CRAC) channel. The invention also relates to pharmaceutical compositions containing such compounds in treating diseases disorders associated with calcium release-activated calcium (CRAC) channel modulators. wherein, ring D is Formula (a) or Formula (b): A and B, which may be same or different, are independently CR3 or N; Y is CR3 or N; L is selected from —NR2C(O)—, —C(O)NR2— and —NR2CRaRb—; Ra and Rb are independently hydrogen, halogen or substituted or unsubstituted alkyl; ring E is selected from the Formula (i) to (vii).

Abstract: A dynamic spectrum arbitrage (DSA) system may include a dynamic spectrum policy controller (DPC) and a dynamic spectrum controller (DSC) that together dynamically manage the allocation and use of resources (e.g., spectrum resources) across different networks. The DPC and DSC may store DSC context information, and use this information to perform various DSA operations. For example, the DSC may determine whether there is bandwidth available for allocation within cells in a first telecommunication network, generate a resource register request message that identifies the amount of bandwidth that is available, and send the generated resource register request message to the DPC using a DSAAP component/protocol. The DSC may receive the resource register response message and a bid success message via the DSAAP, and send a resources allocated message to the DPC via the DSAAP to commit the requested amount of bandwidth for use by the second telecommunication network.

Abstract: A dynamic spectrum arbitrage (DSA) system may include a dynamic spectrum policy controller (DPC) and a dynamic spectrum controller (DSC) that together dynamically manage the allocation and use of resources (e.g., spectrum resources) across different networks. The DPC and DSC may store DSC context information, and use this information to perform various DSA operations. For example, the DSC may determine whether there is bandwidth available for allocation within cells in a first telecommunication network, generate a resource register request message that identifies the amount of bandwidth that is available, and send the generated resource register request message to the DPC using a DSAAP component/protocol. The DSC may receive the resource register response message and a bid success message via the DSAAP, and send a resources allocated message to the DPC via the DSAAP to commit the requested amount of bandwidth for use by the second telecommunication network.

Abstract: A dynamic spectrum arbitrage (DSA) system may include a dynamic spectrum policy controller (DPC) and a dynamic spectrum controller (DSC) that together dynamically manage the allocation and use of resources (e.g., spectrum resources) across different networks. The DSC and/or DPC components may be configured to monitor a congestion state of an eNodeB, and intelligently allocate resources, manage user traffic of the eNodeBs, select target eNodeBs for handovers, determine the quality of service (QoS) levels that are to be given to wireless devices attached to the eNodeBs, and/or perform other similar operations to intelligently manage the allocation and use of resources by the various networks. The DPC and/or DSC components may be also configured to perform these and other operations based on the transitions, changes, transition rates, or rates of change in the congestion levels of the network components.

Abstract: A dynamic spectrum arbitrage (DSA) system may include a dynamic spectrum policy controller (DPC) and a dynamic spectrum controller (DSC) that together dynamically manage the allocation and use of resources (e.g., spectrum resources) across different networks. A wireless device may be configured to intelligently select and use these allocated resources. For example, the wireless device may be configured to traverse an ordered list of preferred of networks to identify and select a first cell site in a first telecommunication network, establish a first communication link between the wireless device and the selected first cell site, receive network information identifying a geographic region in which the wireless device is allowed to use resources of a second telecommunication network, determine whether the wireless device is in the geographical region, and establish a second communication link to a second cell in the second telecommunication network based on the received network information.

Abstract: A dynamic spectrum arbitrage (DSA) system may include a dynamic spectrum policy controller (DPC) and a dynamic spectrum controller (DSC) that together dynamically manage the allocation and use of resources (e.g., spectrum resources) across different networks. The DSC and/or DPC components may be configured to monitor a congestion state of an eNodeB, and intelligently allocate resources, manage user traffic of the eNodeBs, select target eNodeBs for handovers, determine the quality of service (QoS) levels that are to be given to wireless devices attached to the eNodeBs, and/or perform other similar operations to intelligently manage the allocation and use of resources by the various networks. The DPC and/or DSC components may be also configured to perform these and other operations based on the transitions, changes, transition rates, or rates of change in the congestion levels of the network components.

Abstract: The present invention relates to compounds described herein Formula (I) and pharmaceutical acceptable salts thereof, which modulate the activity of calcium release-activated calcium (CRAC) channel. The invention also describes the compounds of Formula (I) and pharmaceutical compositions containing such compounds thereof for treating, managing, and/or lessening the severity of diseases, disorders, syndromes or conditions associated with the modulation of calcium release-activated calcium (CRAC) channel.

Abstract: The present invention relates to compounds described herein Formula (I) and pharmaceutical acceptable salts thereof, which modulate the activity of calcium release-activated calcium (CRAC) channel. The invention also describes the compounds of Formula (I) and pharmaceutical compositions containing such compounds thereof for treating, managing, and/or lessening the severity of diseases, disorders, syndromes or conditions associated with the modulation of calcium release-activated calcium (CRAC) channel.

Abstract: A dynamic spectrum arbitrage (DSA) system may include a dynamic spectrum policy controller (DPC) and a dynamic spectrum controller (DSC) that together dynamically manage the allocation and use of resources (e.g., spectrum resources) across different networks. A dynamic spectrum arbitrage application part (DSAAP) protocol/component/module may allow, facilitate, support, or augment communications between the DSC and DPC so as to improve the efficiency and speed of the DSA system. The DSAAP may allow the DPC and/or DSC components to better pool resources across the different networks, better monitor traffic and resource usage in the various networks, to more efficiently communicate bids and bidding information, to quickly and efficiently register and deregister components, and better perform backoff operations.

Abstract: A dynamic spectrum arbitrage (DSA) system may include a dynamic spectrum policy controller (DPC) and a dynamic spectrum controller (DSC) that together dynamically manage the allocation and use of resources (e.g., spectrum resources) across different networks. A wireless device may be configured to intelligently select and use these allocated resources. For example, the wireless device may be configured to traverse an ordered list of preferred of networks to identify and select a first cell site in a first telecommunication network, establish a first communication link between the wireless device and the selected first cell site, receive network information identifying a geographic region in which the wireless device is allowed to use resources of a second telecommunication network, determine whether the wireless device is in the geographical region, and establish a second communication link to a second cell in the second telecommunication network based on the received network information.

Abstract: A dynamic spectrum arbitrage (DSA) system includes a dynamic spectrum policy controller (DPC) and a dynamic spectrum controller (DSC) that together dynamically manage the allocation and use of resources (e.g., spectrum resources) across different networks. As part of these operations, the DSC may generate a grid-map structure that includes a primary grid structure that identifies telecommunication cells in a geographical area, and monitor the locations of wireless devices with respect to the telecommunication cells of the grid-map structure to determine whether to initiate inter-network handover operations. The DSC may also receive updated information from the monitored wireless devices (e.g.

Abstract: The present invention relates to compounds described herein Formula (I) and pharmaceutical acceptable salts thereof, which modulate the activity of calcium release-activated calcium (CRAC) channel. The invention also describes the compounds of Formula (I) and pharmaceutical compositions containing such compounds thereof for treating, managing, and/or lessening the severity of diseases, disorders, syndromes or conditions associated with the modulation of calcium release-activated calcium (CRAC) channel.

Abstract: A dynamic spectrum arbitrage (DSA) system includes a dynamic spectrum policy controller (DPC) and a dynamic spectrum controller (DSC) that together dynamically manage the allocation and use of resources across different networks. The DSC component may be configured to receive notice that an eNodeB is congested, identify a geographic boundary area for a bid serviced by the congested eNodeB, generate a list of eligible active wireless devices that are inside the geographic boundary area, determine an available resource of target a eNodeB that services the identified geographic boundary area, select for handin to the target eNodeB wireless devices from the received list of eligible active devices, and send a handin initiate communication message to the target eNodeB servicing the wireless devices that are selected for handin.

Abstract: The present invention relates to compounds described herein Formula (I) and pharmaceutical acceptable salts thereof, which modulate the activity of calcium release-activated calcium (CRAC) channel. The invention also describes the compounds of Formula (I) and pharmaceutical compositions containing such compounds thereof for treating, managing, and/or lessening the severity of diseases, disorders, syndromes or conditions associated with the modulation of calcium release-activated calcium (CRAC) channel.

Abstract: A dynamic spectrum arbitrage (DSA) system includes a dynamic spectrum policy controller (DPC) and a dynamic spectrum controller (DSC) that together dynamically manage the allocation and use of resources (e.g., spectrum resources) across different networks. The DSC component may include wired or wireless connections to eNodeBs, a mobility management entity (MME), and various other network components. These components may be configured to communicate and perform various mobility management operations to better manage and coordinate the handling (e.g., handoffs, hand-ins, backoff, etc.) of wireless devices as they are moved with respect to the allocated resources.