Abstract: The present invention relates to a novel compound of 4?-thionucleoside, a preparation method therefor, a pharmaceutical composition comprising the same and an application thereof. Specifically, the present invention relates to a phosphamide derivative of 4?-thionucleoside, a preparation method therefor, a pharmaceutical composition comprising the same, a use thereof in the preparation of a medicine for preventing or treating abnormal cell proliferation diseases (for example, tumors or cancers and related diseases) or virus infectious diseases, and a method of using the same for preventing or treating abnormal cell proliferation diseases (for example, tumors or cancers and related diseases) or virus infectious diseases.

Abstract: A rubber gasket is interposed between opposing two members in a state of being held in a fitting groove formed in one of two members, and includes a concave surface located in a central area in a width direction thereof and extending in a circumferential direction thereof, and seal beads located on both sides of the concave surface in the width direction thereof. The concave surface and the seal beads are formed in each of a surface of the rubber gasket facing a bottom surface of the fitting groove and a surface of the rubber gasket facing the other of two members. Assuming that a maximum depth of the concave surface is D, and a height between the seal beads facing the bottom surface of the fitting groove and the seal beads on an opposite side thereto is A, the expression D=0.025A˜0.075A (1) is satisfied.

Abstract: The invention relates to a polyamide compound and a use thereof. Specifically, the invention relates to a type of polyamide compound (which preferably comprise one or more amide bonds formed by condensation of same or different L-amino acids or D-amino acids), or stereoisomers, crystalline polymorphs, solvates, metabolites, prodrugs or pharmaceutically acceptable salts or esters thereof, or pharmaceutical compositions thereof, as well as a method for preparing the polyamide compound and a use thereof in the prevention or treatment of diseases associated with ?-opioid receptor. The polyamide compound of the invention has excellent ?-opioid receptor agonistic activity and hydrophilicity, thus having a lesser ability of penetrating the blood-brain barrier and a lower capacity for entering the brain.

Abstract: A method, an apparatus, a device and a storage medium for implementing an application based on a blockchain network are provided. The method includes: interacting a basic operation with a user via a blockchain platform access interface carried by a locally configured lightweight node; interacting data of the basic operation with a basic chain node in the blockchain network through data of a basic chain deployed in the lightweight node; interacting an application operation with the user through a locally installed application client; and interacting data of the application operation with a node of an application parallel chain corresponding to the application through data of the application parallel chain deployed in the lightweight node.

Abstract: The present invention relates to novel “reverse amide” compounds comprising a zinc chelator group, and the use of such compounds in the inhibition of HDAC6 and in the treatment of various diseases, disorders or conditions related to HDAC6.

Abstract: Disclosed are devices, systems and methods for processing an image. In one aspect a method includes receiving an image from a sensor array including an x-y array of pixels, each pixel in the x-y array of pixels having a value selected from one of three primary colors, based on a corresponding x-y value in a mask pattern. The method may further include generating a preprocessed image by performing preprocessing on the image. The method may further include performing perception on the preprocessed image to determine one or more outlines of physical objects.

Abstract: The present invention relates to novel 2-acylaminothiazole derivatives. The present invention also relates to the preparation method for these novel 2-acylaminothiazole derivatives and intermediates thereof, and a pharmaceutical composition containing these compounds. Moreover, the present invention also relates to these novel 2-acylaminothiazole derivatives and the pharmaceutical composition containing the same for use in treating and/or preventing thrombopoietin receptor mediated diseases.

Abstract: A thermostat for controlling an HVAC system includes wiring terminals adapted and configured to make an electrical connection with an HVAC system wires such as common, heating and cooling control and return wires. The making of the connection with a common wire actuates switching open a loop of an electrical circuit used for power harvesting. The wiring terminal includes actuation of a moveable part of the terminal so as to accommodate the common wire that in turn actuates the switching open the power harvesting loop. More than one other loop can be switched. The wiring terminal can be used to automatically connect and/or disconnect Rc and Rh circuits when one or both Rc and Rh wires are present. The wiring terminal can be used for electronically sensing the presence of the HVAC system wire.

Abstract: A method for fabricating a resonator structure, comprising engineering dispersion of electromagnetic radiation guided along a boundary of an axially symmetric substrate, the engineering comprising micro-structuring a geometry of the boundary, wherein the structure defines a waveguide for electromagnetic radiation.

Abstract: The present disclosure provides a method for preventing corrosion capable of sufficiently protecting a surface of an aluminum-based member (in particular, a contact surface with a gasket) from corrosion, particularly when the surface of the aluminum-based member is sealed by the gasket. The method for preventing corrosion of a surface of an aluminum-based member constituting a structure that sandwiches the gasket together with another member in a press contact state, wherein a surfactant is made to adhere to the surface of the aluminum-based member.

Abstract: The present disclosure provides a gasket for corrosion prevention, which can exhibit an excellent corrosion protection performance over a long period of time, without changing rubber characteristics of a rubber elastic body itself. The gasket for corrosion prevention includes a rubber elastic body and a surface active agent, and the surface active agent exists at least in an inner part of the rubber elastic body, in an impregnated state in which the surface active agent can exude to a surface of the rubber elastic body.

Abstract: A waterproof connector includes a dielectric body, a plurality of terminals integrally molded to the dielectric body, a shielding assembly, a metal shell surrounding outside the dielectric body, and a waterproof housing integrally molded outside the metal shell. The dielectric body has a tongue board. A periphery of a rear of the tongue board is recessed inward to form a limiting groove. A plurality of the blocking boards are protruded from the tongue board and located in front of the limiting groove. The shielding assembly is limited in the limiting groove. Outer surfaces of rear ends of contact portions of the plurality of the terminals adjacent to a front end of the shielding assembly are recessed inward to form a plurality of avoiding areas, each of the plurality of the avoiding areas is matched with one of the plurality of the blocking boards.

Abstract: A rubber gasket is interposed between opposing two members in a state of being held in a fitting groove formed in one of two members, and includes a concave surface located in a central area in a width direction thereof and extending in a circumferential direction thereof, and seal beads located on both sides of the concave surface in the width direction thereof. The concave surface and the seal beads are formed in each of a surface of the rubber gasket facing a bottom surface of the fitting groove and a surface of the rubber gasket facing the other of two members. Assuming that a maximum depth of the concave surface is D, and a height between the seal beads facing the bottom surface of the fitting groove and the seal beads on an opposite side thereto is A, the expression D=0.025A˜0.075A (1) is satisfied.

Abstract: A display including a display panel and a control module is disclosed. The display panel includes a plurality of same sub-pixel matrixes. Each sub-pixel matrix is formed by arranging a plurality of sub-pixels. The plurality of sub-pixels includes first sub-pixels corresponding to a first color, second sub-pixels corresponding to a second color, and third sub-pixels corresponding to a third color. The first sub-pixels, the second sub-pixels, and the third sub-pixels are all arranged on the display panel to form a shape of fold line having different folding lengths. The control module is coupled to the display panel and used to output a control signal to the display panel according to a display data to drive the plurality of sub-pixels on the display panel.

Abstract: The present invention relates to a novel compound of 4?-thionucleoside, a preparation method therefor, a pharmaceutical composition comprising the same and an application thereof. Specifically, the present invention relates to a phosphamide derivative of 4?-thionucleoside, a preparation method therefor, a pharmaceutical composition comprising the same, a use thereof in the preparation of a medicine for preventing or treating abnormal cell proliferation diseases (for example, tumors or cancers and related diseases) or virus infectious diseases, and a method of using the same for preventing or treating abnormal cell proliferation diseases (for example, tumors or cancers and related diseases) or virus infectious diseases.

Abstract: In a gasket which is installed to an installation groove provided in one member of two members facing to each other and comes into close contact with the other member, and has a seal projection coming into contact with a groove side surface of the installation groove, and provided over a whole periphery of the gasket in a side surface of the gasket, a concavity is provided in a part on a circumference of the gasket in the side surface of the gasket, for venting air when the gasket is installed to the installation groove. The concavity is formed into a shape having a predetermined curvature in a longitudinal direction of the gasket. The gasket can prevent the pressing resistance at a time of installing the gasket from being enlarged, and prevent the gasket from floating up from the installation groove due to the spring back of the sealed air.

Abstract: An electrical connector includes an insulating housing, a plurality of first terminals arranged in the insulating housing, a plurality of second terminals arranged in the insulating housing. Each of terminals includes a contact strip. The contact strip includes a middle-recessed concave surface. By using the structure of the middle-recessed concave surface to decrease the middle thickness of the terminals, the impedance of the terminals is improved and the noise interference of the terminals generated in the high-frequency transmission is efficiently reduced.

Abstract: An electrical connector includes a main body mounted to the circuit board, a shielding plate assembly fastened to the main body, and a plurality of conductive terminals mounted to the main body and arranged in two rows. The shielding plate assembly is located between the two rows of the conductive terminals. Each of the conductive terminals has a fastening portion, a contact portion and a soldering portion. A front end of the contact portion has a contact surface. Thicknesses of two opposite sides of the front end of the contact portion are smaller than a thickness of a middle of the front end of the contact portion. The contact surfaces of the contact portions of the conductive terminals are exposed to a top surface and a bottom surface of the main body, respectively.

Abstract: An electrical junction box includes a casing, a first installation space, a second installation space, and a connection part arranged in the casing the connection part includes a main body, a first connection end, and a second connection end. The main body is used for connecting to a cable; the first connection end, connected to the main body, is located in the first installation space, and is used for connecting to a contactor; and the second connection end, arranged on the first connection end, is located in the second installation space, and may be used for connecting to a resistance wire. The resistance wire may be connected to the second connection end without passing over the junction box, which is not only advantageous for fastening and installing the junction box, but also facilitates the connection and installation of the cable.