Abstract: Ultraviolet (UV) light emission devices and related methods of use. The UV light emission devices disclosed herein are particularly suited for use in disinfecting surfaces and air. The UV light emission devices disclosed herein can be provided in the form factor of a handheld device that is easily held and manipulated by a human user. The human user can manipulate the handheld UV light emission device to decontaminate surfaces, air, and other areas by orienting the handheld UV light emission device so that the UV light emitted from its light source is directed to the area of interest to be decontaminated.

Abstract: A waste heat recovery system comprising a thermal circuit. The thermal circuit includes a boiler and an expander fluidly coupled to the boiler. The thermal circuit further includes a power transfer system integrated to the expander. The power transfer system is configured to receive mechanical energy from the expander. The thermal circuit further includes an ejector fluidly coupled to the boiler and to the power transfer system. The ejector is configured to receive a motive flow of working fluid from the boiler. The ejector is further configured to receive a suction flow of working fluid from the power transfer system. The ejector is further configured to combine the motive flow of working fluid and the suction flow of working fluid.

Abstract: Ultraviolet (UV) light emission devices and related methods of use. The UV light emission devices disclosed herein are particularly suited for use in disinfecting surfaces and air. The UV light emission devices disclosed herein can be provided in the form factor of a handheld device that is easily held and manipulated by a human user. The human user can manipulate the handheld UV light emission device to decontaminate surfaces, air, and other areas by orienting the handheld UV light emission device so that the UV light emitted from its light source is directed to the area of interest to be decontaminated.

Abstract: Systems and methods for handling autonomous vehicle faults are provided. A system includes a plurality of function nodes arranged in a directed graph architecture. The function nodes include a plurality of detector nodes and a plurality of fault handler nodes. Each detector node is communicatively connected to at least one function node and an associated fault handler node. The detector node is configured to obtain output from the function node, detect a fault, and provide a fault event to the associated fault handler node. Each fault handler node can be associated with a fault severity and a corresponding vehicle action. The associated fault handler node can receive the fault event from the detector node and initiate a fault response. The fault response can include initiating a respective vehicle action in response to the fault.

Abstract: Provided herein are compositions and methods for detecting migration of effector cells towards a target cell, and cytotoxicity of the migrated effector cells against the target cells. The effector cells are modified to express a homing or migratory receptor, and the target cells are modified to express the cognate ligand. The methods can be carried out in a Boyden chamber or tranwells with a porous membrane between the wells. The membrane can be coated with an extracellular matrix component to simulate a solid tumor environment.

Abstract: Ultraviolet (UV) light emission devices and related methods of use. The UV light emission devices disclosed herein are particularly suited for use in disinfecting surfaces and air. The UV light emission devices disclosed herein can be provided in the form factor of a handheld device that is easily held and manipulated by a human user. The human user can manipulate the handheld UV light emission device to decontaminate surfaces, air, and other areas by orienting the handheld UV light emission device so that the UV light emitted from its light source is directed to the area of interest to be decontaminated.

Abstract: Modular fluid path assemblies are provided that include conduit, coupling, and needle portions of a fluid path fluidly coupled to an outlet of a container. The modular fluid path assemblies further include a needle shield having a tip of the needle embedded therein. So configured, in embodiments, the modular fluid path assemblies can be sterilized, a medicament can be filled in the container, and a stopper inserted in the container so that the pre-sterilized and pre-filled modular fluid path assemblies can have a closed container integrity (CCI) seal.

Abstract: Within a vehicle, and at a border crossing, a verification device enables unsupervised or automatic biometric authentication of subjects (i.e., persons or travelers) moving between secured areas (e.g., across a border or into a secured facility, for example). Verification device is configured to store reference biometric information for one or more vehicle occupants. Upon approaching a verification station at a border crossing, user(s) supply one or more biometrics (e.g., fingerprint, facial recognition, voice recognition) for validation against the reference biometric information. Upon validation, verification device transmits a validated signal to the verification station to enable the vehicle to pass the border crossing without stopping at the immigration booth. For example, the receipt of a validated signal may trigger the opening of a gate at a border crossing.

Abstract: Ultraviolet (UV) light emission devices and related methods of use. The UV light emission devices disclosed herein are particularly suited for use in disinfecting surfaces and air. The UV light emission devices disclosed herein can be provided in the form factor of a handheld device that is easily held and manipulated by a human user. The human user can manipulate the handheld UV light emission device to decontaminate surfaces, air, and other areas by orienting the handheld UV light emission device so that the UV light emitted from its light source is directed to the area of interest to be decontaminated.

Abstract: Ultraviolet (UV) light emission devices and related methods of use. The UV light emission devices disclosed herein are particularly suited for use in disinfecting surfaces and air. The UV light emission devices disclosed herein can be provided in the form factor of a handheld device that is easily held and manipulated by a human user. The human user can manipulate the handheld UV light emission device to decontaminate surfaces, air, and other areas by orienting the handheld UV light emission device so that the UV light emitted from its light source is directed to the area of interest to be decontaminated.

Abstract: Disclosed are devices, systems, and methods for compact energy conversion. In one aspect, the compact energy conversion device includes a transport medium comprising a nanoparticle suspended in a dielectric. The transport medium has a first side and a second side, with the first side opposing the second side. The nanoparticle comprises a conductive metal. The conductive metal is at least partially covered by a monolayer film. The monolayer film is less conductive than the conductive metal. The compact energy conversion device includes a first surface disposed at the first side of the transport medium, and a second surface disposed at the second side of the transport medium. The first side of the transport medium has a work function lower than the second side. The compact energy conversion device is configured to power an application device coupled to the energy conversion device.

Abstract: Disclosed are devices, systems, and methods for compact energy conversion. In one aspect, the compact energy conversion device includes a transport medium comprising a nanoparticle suspended in a dielectric. The transport medium has a first side and a second side, with the first side opposing the second side. The nanoparticle comprises a conductive metal. The conductive metal is at least partially covered by a monolayer film. The monolayer film is less conductive than the conductive metal. The compact energy conversion device includes a first surface disposed at the first side of the transport medium, and a second surface disposed at the second side of the transport medium. The first side of the transport medium has a work function lower than the second side.

Abstract: A device includes a balloon configured for inflation with a light-diffusing fluid and configured, upon inflation, to expand a body lumen within which it is positioned and a flexible light-emitting device attached to the balloon having a light-emitting side facing radially inward toward the fluid so that, during a medical procedure, light emitted from the light-emitting side is diffused by the fluid and illuminates a treatment area within the body lumen proximal to the balloon.

Abstract: A device for treating hemorrhoids includes a first ligating member which moves between a first position in which the first member is tightened to a degree required to maintain a desired position of the first member around the first portion without significantly cutting off blood flow and a second configuration in which the first member is cinched down around the first portion to substantially cut off blood flow to the encircled first portion. Also, the device includes a first applicator having a proximal lumen and first and second opposed distal lumens open to the proximal lumen. The first member is extending from a proximal end distally through the proximal lumen into the first lumen to exit a distal end of the first lumen, loop around and enter the distal end of the second lumen. The first member is passing through the second lumen into the proximal lumen.

Abstract: A control system and method determine an energy demand associated with delivery of cargo in a trip. The energy demand represents how much electric energy is needed to move cargo vehicles that carry the cargo through the trip. Locations of energy tenders and states of charge of the energy tenders are determined. A schedule for the cargo vehicles to deliver the cargo to a delivery location within a delivery time slot is determined. This schedule is determined based on the energy demand, the locations of the energy tenders, and the states of charge of the energy tenders. The system and method direct which of the energy tenders that the cargo vehicles are to couple with, be powered by, and move with for powering the cargo along routes to the delivery location of the trip within the designated time slot.

Abstract: A dispensing device, comprising a plurality of microfluidic pumps, microfluidic valves, and a microfluidic mixer chip, for receiving and mixing microfluidic amounts of a plurality of fluids having differing viscosities, is disclosed. The device includes a plurality of pathways for moving fluids from associated reservoirs to the microfluidic mixer chip. A mix controller controls the microfluidic pumps and valves so that the fluids, having different viscosities, can be accurately mixed at specified microfluidic amounts or volumes according to a specified microfluidic recipe, and the microfluidic mixture dispensed from the device. The device can be in communication with a software application implemented on a mobile compute device, such as a smartphone, and receive instructions for implementing the specified microfluidic recipe from the software application such that the operation of device components is at the direction of the software application executed on the mobile compute device.

Abstract: Within environments, such as audio-video environments, users may synchronize output of multiple media source(s). To synchronize the output of the media source(s), users may define setting(s) associated with outputting the media source(s) at one or more devices. For example, the user may delay or accelerate the output of audio and/or video sources. Interfaces presented on one or more of the devices may allow the user to change the settings. For environments including multiple users, each user may define setting(s) associated with each user to synchronize output of their associated media source(s). Recommendations may be provided to users, that when implemented, attempt to synchronize the media sources.

Abstract: A control system and method determine an energy demand associated with delivery of cargo in a trip. The energy demand represents how much electric energy is needed to move cargo vehicles that carry the cargo through the trip. Locations of energy tenders and states of charge of the energy tenders are determined. A schedule for the cargo vehicles to deliver the cargo to a delivery location within a delivery time slot is determined. This schedule is determined based on the energy demand, the locations of the energy tenders, and the states of charge of the energy tenders. The system and method direct which of the energy tenders that the cargo vehicles are to couple with, be powered by, and move with for powering the cargo along routes to the delivery location of the trip within the designated time slot.

Abstract: The invention provides compositions including a fusion polypeptide and methods for making a fusion polypeptide that includes a COF1/CRBN-binding polypeptide, COF2/CRBN-binding polypeptide, or COF3/CRBN-binding polypeptide and a heterologous polypeptide of interest.

Abstract: Methods, systems and devices for evaluating a product sampling event. The disclosed methods, systems and devices receive from a user a user identification specific to the user and compare the user identification to a user data set stored on a computer-readable medium. A sample is then delivered based on a predetermined condition, and a product value is changed after the step of causing delivery of the sample of the product. It can then be determined whether the user purchased the product after delivery of the sample of the product and, based on that determination, a sampling event value can be assigned. The user's preferences can also be used to provide a more custom sample with a user's order for example, with online or home delivery shopping.