Patents by Inventor Neng Yang

Neng Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NK1 Antagonists
    Publication number: 20120295879
    Abstract: A compound having the general structure shown in Formula I: or pharmaceutically acceptable salts and/or solvates thereof are useful in treating diseases or conditions mediated by NK1 receptors, for example various physiological disorders, symptoms or diseases, including emesis, depression, anxiety and cough.
    Type: Application
    Filed: September 26, 2011
    Publication date: November 22, 2012
    Applicant: OPKO HEALTH, INC.
    Inventors: Anandan Palani, Xianhai Huang, Dong Xiao, Sapna S. Shah, Sunil Paliwal, Hon-Chung Tsui, Michelle Laci Wrobleski, Ashwin U. Rao, Cheng Wang, Neng-Yang Shih
  • METHOD FOR FABRICATING LIQUID CRYSTAL DISPLAY
    Publication number: 20120252299
    Abstract: The invention provides a method for fabricating a liquid crystal display, including: providing a first substrate and a second substrate, wherein the first substrate and the second substrate are disposed oppositely to each other; filling a mixed solution between the first substrate and the second substrate, wherein the mixed solution comprises a plurality of liquid crystal molecules and a plurality of monomers; performing a UV light irradiation process to the mixed solution, wherein the monomers are polymerized to form a first alignment control layer on a surface of the first substrate facing the liquid crystal molecules, and form a second alignment control layer on a surface of the second substrate facing the liquid crystal molecules, and the thickness of the first alignment control layer and that of the second alignment control layer have a ratio of about 1/2-2/1.
    Type: Application
    Filed: March 12, 2012
    Publication date: October 4, 2012
    Applicants: CHIMEI INNOLUX CORPORATION, INNOCOM TECHNOLOGY(SHENZHEN) CO., LTD.
    Inventors: Hung-Ming SHEN, Kai-Neng Yang, Wan-Ling Huang
  • NKantagonists
    Patent number: 8273895
    Abstract: A NK1 antagonist having the formula (I), wherein Ar1 and Ar2 are optionally substituted phenyl or heteroaryl, X1 is an ether, thio or imino linkage, R4 and R5 are not both H or alkyl, and the remaining variables are as defined in the specification, useful for treating a number of disorders, including emesis, depression, anxiety and cough. Pharmaceutical compositions. Methods of treatment and combinations with other agents are also disclosed.
    Type: Grant
    Filed: December 14, 2010
    Date of Patent: September 25, 2012
    Assignee: Opko Health, Inc.
    Inventors: Sunil Paliwal, Gregory A. Reichard, Cheng Wang, Dong Xiao, Hon-Chung Tsui, Neng-Yang Shih, Juan D. Arredondo, Michelle Laci Wrobleski, Anandan Palani
  • Method of fabricating thin film interface for internal light reflection and impurities isolation
    Patent number: 8273650
    Abstract: A high-quality epitaxial silicon thin layer is formed on an upgraded metallurgical grade silicon (UMG-Si) substrate. A thin film interface is fabricated between the UMG-Si substrate and the epitaxial silicon thin layer. The interface is capable of internal light reflection and impurities isolation. With the interface, photoelectrical conversion efficiency is improved. Thus, the present invention is fit to be applied for making solar cell having epitaxial silicon thin layer.
    Type: Grant
    Filed: November 16, 2009
    Date of Patent: September 25, 2012
    Assignee: Atomic Energy Council—Institute of Nuclear Energy Research
    Inventor: Tsun-Neng Yang
  • 5, 6-ring annulated indole derivatives and use thereof
    Patent number: 8268803
    Abstract: The present invention relates to 5,6-ring annulated indole derivatives of the formula (I), compositions comprising at least one 5,6-ring annulated indole derivatives, and methods of using the 5,6-ring annulated indole derivatives for treating or preventing a viral infection or a virus-related disorder in a patient.
    Type: Grant
    Filed: December 17, 2007
    Date of Patent: September 18, 2012
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Frank Bennett, Srikanth Venkatraman, F. George Njoroge, Kevin X. Chen, Neng-Yang Shih, Stuart B. Rosenblum, Joseph A. Kozlowski
  • Method of fabricating silicon nanowire solar cell device having upgraded metallurgical grade silicon substrate
    Patent number: 8207013
    Abstract: A simplified method for fabricating a solar cell device is provided. The solar cell device has silicon nanowires (SiNW) grown on an upgraded metallurgical grade (UMG) silicon (Si) substrate. Processes of textured surface process and anti-reflection thin film process can be left out for further saving costs on equipment and manufacture investment. Thus, a low-cost Si-based solar cell device can be easily fabricated for wide application.
    Type: Grant
    Filed: September 17, 2010
    Date of Patent: June 26, 2012
    Assignee: Atomic Energy Council Institute of Nuclear Energy Research
    Inventor: Tsun-Neng Yang
  • HETEROCYCLIC COMPOUNDS WITH CXCR3 ANTAGONIST ACTIVITY
    Publication number: 20120157466
    Abstract: The present application discloses a compound, or enantiomers, stereoisomers, rotamers, tautomers, racemates or prodrug of said compound, or pharmaceutically acceptable salts, solvates or esters of said compound, or of said prodrug, said compound having the general structure shown in Formula 1 or Formula 5: or a pharmaceutically acceptable salt, solvate or ester thereof. Also disclosed is a method of treating chemokine mediated diseases, such as, palliative therapy, curative therapy, prophylactic therapy of certain diseases and conditions such as inflammatory diseases (non limiting example(s) include, psoriasis), autoimmune diseases (non limiting example(s) include, rheumatoid arthritis, multiple sclerosis), graft rejection (non limiting example(s) include, allograft rejection, zenograft rejection), infectious diseases (e.
    Type: Application
    Filed: December 20, 2007
    Publication date: June 21, 2012
    Inventors: Qingbei Zeng, Stuart B. Rosenblum, Joseph A. Kozlowski, Neng-Yang Shih, Brian F. McGuinness, Douglas W. Hobbs
  • Compounds for the treatment of inflammatory disorders
    Patent number: 8178553
    Abstract: This invention relates to compounds of the Formula (I): or a pharmaceutically acceptable salt, solvate or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF-? or combinations thereof.
    Type: Grant
    Filed: January 20, 2010
    Date of Patent: May 15, 2012
    Assignee: Schering Corporation
    Inventors: Brian J. Lavey, Joseph A. Kozlowski, Guowei Zhou, Ling Tong, Wensheng Yu, Michael K. C. Wong, Shankar B. Bandarpalle, Neng-Yang Shih, M. Arshad Siddiqui, Kristin E. Rosner, Chaoyang Dai, Janeta Popovici-Muller, Vinay M. Girijavallabhan, Dansu Li, Aneta Maria Kosinski, Seong-Heon Kim, De-Yi Yang, Razia K. Rizvi
  • Hydrochloride salts of 8-[{1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy)-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one and preparation process therefor
    Patent number: 8178550
    Abstract: Disclosed are hydrochloride and tosylate crystalline salt forms of (5S,8S)-8-[{(1R)-1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diazaspiro[4.5]decan-2-one, represented by Formula I and methods of preparing the same.
    Type: Grant
    Filed: April 4, 2007
    Date of Patent: May 15, 2012
    Assignee: OPKO Health, Inc.
    Inventors: Mengwei Hu, Sunil Paliwal, Neng-Yang Shih, Frank Bruno Guenter, Ingrid Mergelsberg
  • ETHYNYL-SUBSTITUTED PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATING VIRAL INFECTIONS
    Publication number: 20120107271
    Abstract: The present invention provides compounds of Formula (I): (Chemical formula should be inserted here as it appears on abstract in paper form) (I) and tautomers, isomers, and esters of said compounds, and pharmaceutically acceptable salts, solvates, and pro-drugs of said compounds, wherein each of R, R1, X, Y, Z, R2, R3, R4, R5, R6, R7, R8, R9, R18, R19 and n is selected independently and as defined herein. Compositions comprising such compounds are also provided. The compounds of the invention are effective as inhibitors of HCV, and are useful, alone and together with other therapeutic agents, in treating or preventing diseases or disorders such as viral infections and virus-related disorders.
    Type: Application
    Filed: August 19, 2009
    Publication date: May 3, 2012
    Inventors: Cecil D. Kwong, F. George Njoroge, Subramaniam Ananthan, Ashok Arasappan, Frank Bennett, Jeremy Clark, Anita T. Fowler, Feng Geng, Hollis S. Kezar, III, Joseph A. Maddry, John J. Piwinski, Robert C. Reynolds, Abhijit Roychowdhury, John A. Secrist, III, Neng-Yang Shih
  • 2,3-substituted indole derivatives for treating viral infections
    Patent number: 8143305
    Abstract: The present invention relates to 2,3-Substituted Indole Derivatives, compositions comprising at least one 2,3-Substituted Indole Derivative, and methods of using the 2,3-Substituted Indole Derivatives for treating or preventing a viral infection or a virus-related disorder in a patient.
    Type: Grant
    Filed: August 27, 2008
    Date of Patent: March 27, 2012
    Assignee: Schering Corporation
    Inventors: Gopinadhan N. Anilkumar, Frank Bennett, Tin-Yau Chan, Kevin X. Chen, Mousumi Sannigrahi, Francisco Velazquez, Srikanth Venkatraman, Qingbei Zeng, Jose S. Duca, Charles A. Lesburg, Joseph A. Kozlowski, F. George Njoroge, Stuart B. Rosenblum, Neng-Yang Shih, Stephen J. Gavalas, Yueheng Jiang, Patrick A. Pinto, Haiyan Pu, Oleg B. Selyutin, Bancha Vibulbhan, Li Wang, Wanli Wu, Weiying Yang, Yuhua Huang, Hsueh-Cheng Huang, Robert Palermo, Boris Feld
  • Method of Fabricating Silicon Nanowire Solar Cell Device Having Upgraded Metallurgical Grade Silicon Substrate
    Publication number: 20120070938
    Abstract: A simplified method for fabricating a solar cell device is provided. The solar cell device has silicon nanowires (SiNW) grown on an upgraded metallurgical grade (UMG) silicon (Si) substrate. Processes of textured surface process and anti-reflection thin film process can be left out for further saving costs on equipment and manufacture investment. Thus, a low-cost Si-based solar cell device can be easily fabricated for wide application.
    Type: Application
    Filed: September 17, 2010
    Publication date: March 22, 2012
    Applicant: ATOMIC ENERGY COUNCIL-INSTITUTE OF NUCLEAR ENERGY RESEARCH
    Inventor: Tsun-Neng Yang
  • Fan and frame thereof
    Patent number: 8100674
    Abstract: A fan has a fan frame for accommodating a first circuit board and a second circuit board. A fan frame includes a housing, a base, and at least one supporting element. The base is disposed in the housing, and the base includes a bottom portion and a tube portion, which is connected to and extended from the bottom portion. The supporting element is connected between the housing and the base. There is a predetermined distance between the bottom portion of the base and an end of the housing so as to form an accommodating space, the first circuit board is disposed on the base and is located on a first side of the bottom portion facing the tube portion, and the second circuit board is disposed in the accommodating space which is located on a second side of the bottom portion facing away from the tube portion.
    Type: Grant
    Filed: September 7, 2007
    Date of Patent: January 24, 2012
    Assignee: Delta Electronics, Inc.
    Inventors: Wei-Yi Lin, Hui-Neng Yang, Po-Hui Shen, Cheng-Chieh Liu, Kun-Ming Lee, Cheng-Wei Yan
  • SUBSTITUTED PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATING VIRAL INFECTIONS
    Publication number: 20110318305
    Abstract: The present invention provides compounds of Formula (I): and tautomers, isomers, and esters of said compounds, and pharmaceutically acceptable salts, solvates, and prodrugs of said compounds, wherein each of R, R1, X, Y, Z, R2, R3, R4, R5, R6, R7, R8, R9, R18, R19 and n is selected independently and as defined herein. Compositions comprising such compounds are also provided. The compounds of the invention are effective as inhibitors of HCV, and are useful, alone and together with other therapeutic agents, in treating or preventing diseases or disorders such as viral infections and virus-related disorders.
    Type: Application
    Filed: August 19, 2009
    Publication date: December 29, 2011
    Inventors: Ashok Arasappan, F. George Njoroge, Cecil D. Kwong, Subramaniam Ananthan, Frank Bennett, Jeremy Clark, Hollis S. Kezar, III, Vinay M. Girijavallabhan, Yuhua Huang, Regina Huelgas, Joseph A. Maddry, John J. Piwinski, Robert C. Reynolds, Abhijit Roychowdhury, Anita T. Fowler, Feng Geng, John A. Secrist, III, Neng-Yang Shih, Vishal Verma, Francisco Velazquez, Srikanth Venkatraman
  • SPRAYING DEVICE
    Publication number: 20110308450
    Abstract: A spraying device to be used in an image transfer process is provided, which includes at least one nozzle. A fluid is supplied to each nozzle, and the nozzles spray the fluid on a substrate to form a liquid film. Further, a dual fluid spraying device is also provided. A dual fluid formed by mixing a liquid with a gas is sprayed on a substrate through at least one nozzle of the spraying device, so as to form a thinner and more uniform liquid film. A photoresist can be laminated to a substrate having the liquid film applied to it with the spraying device to afford enhanced conformability of the photoresist in the substrate in the resulting laminate. This enhanced conformability affords reduced defectivity levels in subsequent processing steps during PCB (printed circuit board) manufacture.
    Type: Application
    Filed: December 15, 2010
    Publication date: December 22, 2011
    Applicant: E.I. DU PONT DE NEMOURS AND COMPANY
    Inventors: CHIN-TA CHEN, Lungchen Chen, Kuo-Chen Lee, Hsiang Neng Yang
  • AZO-SUBSTITUTED PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATING VIRAL INFECTIONS
    Publication number: 20110286964
    Abstract: The present invention provides compounds of Formula (I): (Chemical formula should be inserted here as it appears on abstract in paper form) (I) and tautomers, isomers, and esters of said compounds, and pharmaceutically acceptable salts, solvates, and prodrugs of said compounds, wherein each of R, R1, X, Y, Z, R2, R3, R4, R5, R6, R7, R8, R9, R18, R19, and n is selected independently and as defined herein. Compositions comprising such compounds are also provided. The compounds of the invention are effective as inhibitors of HCV, and are useful, alone and together with other therapeutic agents, in treating or preventing dieases or disorders such as viral infections and virus-related disorders.
    Type: Application
    Filed: August 19, 2009
    Publication date: November 24, 2011
    Inventors: Cecil D. Kwong, F. George Njoroge, Subramaniam Ananthan, Feng Geng, Hollis S. Kezar, III, Joseph A. Maddry, John J. Piwinski, Robert C. Reynolds, John A. Secrist, III, Neng-Yang Shih
  • ETHENYL-SUBSTITUTED PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATING VIRAL INFECTIONS
    Publication number: 20110286965
    Abstract: The present invention provides compounds of Formula (A): (Chemical formula should be inserted here as it appears on abstract in paper form) (A) and tautomers, isomers, and esters of said compounds, and pharmaceutically acceptable salts, solvates, and prodrugs of said compounds, wherein wherein each of R, R1, X, Y, Z, R2, R3, R4, R5, R6, R7, R8, R9, R18, R19, R22, R23, and n is selected independently and as defined herein. Compositions comprising such compounds are also provided. The compounds of the invention are effective as inhibitors of HCV, and are useful, alone and together with other therapeutic agents, in treating or preventing diseases or disorders such as viral infections and virus-related disorders.
    Type: Application
    Filed: August 19, 2009
    Publication date: November 24, 2011
    Inventors: Cecil D. Kwong, F. George Njoroge, Subramaniam Ananthan, Jeremy Clark, Feng Geng, Hollis S. Kezar, III, Joseph A. Maddry, John J. Piwinski, Robert C. Reynolds, Abhijit Roychowdhury, John A. Secrist, III, Neng-Yang Shih
  • Method for making titanium-based compound film of poly silicon solar cell
    Patent number: 8053038
    Abstract: A method is disclosed for making a titanium-based compound film of a poly-silicon solar cell. In the method, a ceramic substrate is made of aluminum oxide. The ceramic substrate is coated with a titanium film in an e-gun evaporation system. Dichlorosilane is provided on the titanium film by atmospheric pressure chemical vapor deposition. A titanium-based compound film is formed on the ceramic substrate.
    Type: Grant
    Filed: September 18, 2007
    Date of Patent: November 8, 2011
    Assignee: Atomic Energy Council-Institute of Nuclear Energy Research
    Inventors: Tsun-Neng Yang, Shan-Ming Lan, Chin-Chen Chiang, Wei-Yang Ma, Chien-Te Ku, Yu-Hsiang Huang
  • NKantagonists
    Patent number: 8026364
    Abstract: A compound having the general structure shown in Formula I: or pharmaceutically acceptable salt and/or solvates thereof are useful in treating diseases or conditions mediated by NK1 receptors, for example various physiological disorders, symptoms or diseases, including emesis, depression, anxiety and cough.
    Type: Grant
    Filed: March 30, 2010
    Date of Patent: September 27, 2011
    Assignee: OPKO Health, Inc.
    Inventors: Sapna S. Shah, Anandan Palani, Xianhai Huang, Dong Xiao, Sunil Paliwal, Hon-Chung Tsui, Michelle Laci Wrobleski, Ashwin U. Rao, Cheng Wang, Neng-Yang Shih
  • Method for making a planar concentrating solar cell assembly with silicon quantum dots
    Patent number: 8021909
    Abstract: Disclosed is a method for making a silicon quantum dot planar concentrating solar cell. At first, silicon nitride or silicon oxide mixed with silicon quantum dots is provided on a transparent substrate. By piling, there is formed a planar optical waveguide for concentrating sunlit into a small dot cast on a small solar cell.
    Type: Grant
    Filed: January 13, 2010
    Date of Patent: September 20, 2011
    Assignee: Atomic Energy Council - Institute of Nuclear Research
    Inventor: Tsun-Neng Yang