Patents by Inventor Norman A. Nelson

Norman A. Nelson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-Decarboxy-2-hydroxymethyl-9-deoxy-9,10-didehydro-PGD.sub.1 analogs
    Patent number: 4088693
    Abstract: This invention comprises certain analogs of the prostaglandins in which the C-1 carboxyl is replaced by a primary alcohol. Also provided in this invention, are novel chemical processes useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.
    Type: Grant
    Filed: April 6, 1977
    Date of Patent: May 9, 1978
    Assignee: The Upjohn Company
    Inventor: Norman A. Nelson
  • 2-Decarboxy-2-hydroxymethyl-11-deoxy-PGE.sub.2 analogs
    Patent number: 4088694
    Abstract: This invention comprises certain analogs of the prostaglandins in which the C-1 carboxyl is replaced by a primary alcohol. Also provided in this invention, are novel chemical processes useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.
    Type: Grant
    Filed: April 6, 1977
    Date of Patent: May 9, 1978
    Assignee: The Upjohn Company
    Inventor: Norman A. Nelson
  • 16-Phenoxy prostaglandin A2 analogs
    Patent number: 4087616
    Abstract: Prostaglandin-type compounds with a phenoxy or substituted-phenoxy substituent at the C-16 position are disclosed, with processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, labor inducement at term, and wound healing.
    Type: Grant
    Filed: February 7, 1977
    Date of Patent: May 2, 1978
    Assignee: The Upjohn Company
    Inventor: Norman A. Nelson
  • 3-(1'-Hydroxy-2'-hydroxyethyl)-4,6-dihydroxyhexanoic acid 4.gamma. lactone derivatives
    Patent number: 4086247
    Abstract: The present specification provides novel intermediates and novel processes for the synthesis of Thromboxane B.sub.2 11a-homo-11a-oxa-PGF.sub.2.alpha.), its 15-epimer, and various carboxyl derivatives thereof. In particular, there are disclosed various bicyclic tetrahydrofuran-containing lactones useful in the above processes, and corresponding acyclic lactones.
    Type: Grant
    Filed: May 12, 1977
    Date of Patent: April 25, 1978
    Assignee: The Upjohn Company
    Inventor: Norman A. Nelson
  • 2-Decarboxy-2-amino-methyl-PGE and PGD analogs
    Patent number: 4085139
    Abstract: Prostaglandin analogs wherein the C-2 carboxy is replaced by an aminomethyl or (substituted amino)methyl are disclosed along with intermediates useful in their preparation and processes for their preparation. These analogs are useful for the same pharmacological purposes as the prostaglandins.
    Type: Grant
    Filed: August 30, 1976
    Date of Patent: April 18, 1978
    Assignee: The Upjohn Company
    Inventor: Norman A. Nelson
  • 3(1'-Hydroxy-2'-hydroxyethyl)-4-hydroxy-6-silyloxyhexanoic acid 4.alpha.lactone derivatives
    Patent number: 4085120
    Abstract: The present specification provides novel intermediates and novel processes for the synthesis of Thromboxane B.sub.2 11a-homo-11a-oxa-PGF.sub.2.alpha.), Its 15-epimer, and various carboxyl derivatives thereof. In particular, there are disclosed various bicyclic tetrahydrofuran-containing lactones useful in the above processes, and corresponding acyclic lactones.
    Type: Grant
    Filed: May 12, 1977
    Date of Patent: April 18, 1978
    Assignee: The Upjohn Company
    Inventor: Norman A. Nelson
  • 4,5,6-Trinor-3,7-inter-m-phenylene prostaglandin F.sub.1.alpha. analogs
    Patent number: 4084058
    Abstract: This invention is a group of 4,5,6-trinor-3,7-inter-m-phenylene prostaglandin-type compounds and processes for making them. These compounds are useful for a variety of pharmacological purposes, including hypotensive control and inhibition of platelet aggregation.A typical formula for a PGF.sub.1.alpha.
    Type: Grant
    Filed: January 31, 1977
    Date of Patent: April 11, 1978
    Assignee: The Upjohn Company
    Inventor: Norman A. Nelson
  • 6-Alkoxy-4.alpha.-hydroxy-2.beta.-tetrahydropyranacetic acid .gamma.-lactones
    Patent number: 4082776
    Abstract: The present specification provides novel intermediates and novel processes for the synthesis of Thromboxane B.sub.2 11a- homo-11a-oxa-PGF.sub.2.alpha.), its 15-epimer, and various carboxyl derivatives thereof. In particular, there are disclosed various bicyclic tetrahydropyran-containing lactones useful in the above processes, and corresponding acyclic lactones.
    Type: Grant
    Filed: February 22, 1977
    Date of Patent: April 4, 1978
    Assignee: The Upjohn Company
    Inventors: Robert C. Kelly, Norman A. Nelson
  • 2-Decarboxy-2-amino-methyl-PGF.sub..alpha. compounds
    Patent number: 4081478
    Abstract: Prostaglandin analogs wherein the C-2 carboxy is replaced by an aminomethyl or (substituted amino)methyl are disclosed along with intermediates useful in their preparation and processes for their preparation. These analogs are useful for the same pharmacological purposes as the prostaglandins.
    Type: Grant
    Filed: August 30, 1976
    Date of Patent: March 28, 1978
    Assignee: The Upjohn Company
    Inventor: Norman A. Nelson
  • 2-Decarboxy-2-hydroxymethyl-3,7-inter-m-phenylene-3-oxa-PGE.sub.1 compounds
    Patent number: 4076751
    Abstract: This invention comprises certain analogs of the prostaglandins in which the C-1 carboxyl is replaced by a primary alcohol. Also provided in this invention, are novel chemical processes useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.
    Type: Grant
    Filed: March 17, 1977
    Date of Patent: February 28, 1978
    Assignee: The Upjohn Company
    Inventor: Norman A. Nelson
  • 2-Decarboxy-2-hydroxymethyl-3,7-inter-m-phenylene-PGE.sub.1 compounds
    Patent number: 4076753
    Abstract: This invention comprises certain analogs of the prostaglandins in which the C-1 carboxyl is replaced by a primary alcohol. Also provided in this invention, are novel chemical processes useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.
    Type: Grant
    Filed: March 17, 1977
    Date of Patent: February 28, 1978
    Assignee: The Upjohn Company
    Inventor: Norman A. Nelson
  • 2 -Decarboxy-2-hydroxymethyl-3,7-inter-m-phenylene-3-oxa-9-deoxy-PGD.sub.1 compounds
    Patent number: 4076750
    Abstract: This invention comprises certain analogs of the prostaglandins in which the C-1 carboxyl is replaced by a primary alcohol. Also provided in this invention, are novel chemical processes useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.
    Type: Grant
    Filed: March 17, 1977
    Date of Patent: February 28, 1978
    Assignee: The Upjohn Company
    Inventor: Norman A. Nelson
  • 2-Decarboxy-2-hydroxymethyl-3,7-inter-m-phenylene-3-oxa-9-deoxy-9,10-dide hydro-PGD.sub.1 compounds
    Patent number: 4076752
    Abstract: This invention comprises certain analogs of the prostaglandins in which the C-1 carboxyl is replaced by a primary alcohol. Also provided in this invention, are novel chemical processes useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.
    Type: Grant
    Filed: March 17, 1977
    Date of Patent: February 28, 1978
    Assignee: The Upjohn Company
    Inventor: Norman A. Nelson
  • 2-Decarboxy-2-hydroxymethyl-3,7-inter-m-phenylene-3-oxa-11-deoxy-PGE. sub.1 compounds
    Patent number: 4075247
    Abstract: This invention comprises certain analogs of the prostaglandins in which the C-1 carboxyl is replaced by a primary alcohol. Also provided in this invention, are novel chemical processes useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.
    Type: Grant
    Filed: March 17, 1977
    Date of Patent: February 21, 1978
    Assignee: The Upjohn Company
    Inventor: Norman A. Nelson
  • 2-Decarboxy-2-hydroxymethyl-3,7-inter-m-phenylene-11-deoxy-PGE.sub.1 compounds
    Patent number: 4073805
    Abstract: This invention comprises certain analogs of the prostaglandins in which the C-1 carboxyl is replaced by a primary alcohol. Also provided in this invention, are novel chemical processes useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.
    Type: Grant
    Filed: March 17, 1977
    Date of Patent: February 14, 1978
    Assignee: The Upjohn Company
    Inventor: Norman A. Nelson
  • 2-Decarboxy-2-amino-methyl-PGA and 9-deoxy-9,10-didehydro-PGD analogs
    Patent number: 4073808
    Abstract: Prostaglandin analogs wherein the C-2 carboxy is replaced by an aminomethyl or (substituted amino)methyl are disclosed along with intermediates useful in their preparation and processes for their preparation. These analogs are useful for the same pharmacological purposes as the prostaglandins.
    Type: Grant
    Filed: August 30, 1976
    Date of Patent: February 14, 1978
    Assignee: The Upjohn Company
    Inventor: Norman A. Nelson
  • 2-Decarboxy-2-hydroxymethyl-3,7-inter-m-phenylene-PGD, compounds
    Patent number: 4067907
    Abstract: This invention comprises certain analogs of the prostaglandins in which the C-1 carboxyl is replaced by a primary alcohol. Also provided in this invention, are novel chemical processes useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.
    Type: Grant
    Filed: March 17, 1977
    Date of Patent: January 10, 1978
    Assignee: The Upjohn Company
    Inventor: Norman A. Nelson
  • 2-Decarboxy-2-hydroxymethyl-3,7-inter-m-phenylene-9-dioxy-PGD.sub.1 compounds
    Patent number: 4066701
    Abstract: This invention comprises certain analogs of the prostaglandins in which the C-1 carboxyl is replaced by a primary alcohol. Also provided in this invention, are novel chemical processes useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.
    Type: Grant
    Filed: March 17, 1977
    Date of Patent: January 3, 1978
    Assignee: The Upjohn Company
    Inventor: Norman A. Nelson
  • Miniature hurricane lamp for dollhouses and the like
    Patent number: D246932
    Type: Grant
    Filed: July 12, 1976
    Date of Patent: January 10, 1978
    Assignee: Nelson Tool & Machine Company, Inc.
    Inventor: Norman Nelson
  • Miniature candlestick for dollhouses and the like
    Patent number: D247456
    Type: Grant
    Filed: July 12, 1976
    Date of Patent: March 7, 1978
    Assignee: Nelson Tool and Machine Company, Inc.
    Inventor: Norman Nelson