Patents by Inventor Palle Christophersen

Palle Christophersen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SUBSTITUTED [1,2,4]TRIAZOLO[1,5-a]PYRIMIDINES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS
    Publication number: 20120088780
    Abstract: This invention relates to novel substituted [1,2,4]triazolo[1,5-a]pyrimidines and their use as modulators of potassium channels. In other aspects the invention relates to the use of these compounds, in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: March 30, 2010
    Publication date: April 12, 2012
    Applicant: NEUROSEARCH A/S
    Inventors: Ulrik Svane Sørensen, Birgitte L. Eriksen, Charlotte Hougaard, Dorte Strøbaek, Palle Christophersen
  • PURINYL DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS
    Publication number: 20120004246
    Abstract: This invention relates to novel purinyl derivatives and their use as potassium channel modulating agents. Moreover the invention is directed to pharmaceutical compositions useful for the treatment or alleviation of diseases or disorders associated with the activity of potassium channels.
    Type: Application
    Filed: March 27, 2008
    Publication date: January 5, 2012
    Applicant: NeuroSearch A/S
    Inventors: Birgitte L. Eriksen, Ulrik Svane Sorensen, Charlotte Hougaard, Dan Peters, Palle Christophersen
  • Guanidine derivatives and their medical use
    Patent number: 8048877
    Abstract: This invention relates to novel guanidine derivatives useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Grant
    Filed: March 22, 2007
    Date of Patent: November 1, 2011
    Assignee: Neurosearch A/S
    Inventors: Ulrik Svane Sørensen, Birgitte L. Eriksen, Lene Teuber, Dan Peters, Dorte Strøbæk, Tina Holm Johansen, Palle Christophersen
  • 2-aminio-pyridine derivatives and their use as potassium channel modulators
    Patent number: 8039632
    Abstract: This invention relates to novel 2-amino-pyridine derivative useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Grant
    Filed: November 12, 2007
    Date of Patent: October 18, 2011
    Assignee: Neurosearch A/S
    Inventors: Ulrik Svane Sørensen, Birgitte L. Eriksen, Lene Teuber, Dan Peters, Dorte Strøbæk, Tina Holm Johansen, Palle Christophersen
  • SUBSTITUTED PURINYL-PYRAZOL DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS
    Publication number: 20110251217
    Abstract: This invention relates to novel substituted purinyl-pyrazol derivatives of formula (I) and their use as potassium channel modulating agents. Moreover the invention is directed to pharmaceutical compositions useful for the treatment or alleviation of diseases or disorders associated with the activity of potassium channels.
    Type: Application
    Filed: September 22, 2009
    Publication date: October 13, 2011
    Applicant: NEUROSEARCH A/S
    Inventors: Birgitte L. Eriksen, Charlotte Hougaard, Dan Peters, Palle Christophersen
  • SUBSTITUTED PURINYL-PYRAZOL DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS
    Publication number: 20110237607
    Abstract: This invention relates to novel substituted purinyl-pyrazol derivatives (I) and their use as potassium channel modulating agents. Moreover the invention is directed to pharmaceutical compositions useful for the treatment or alleviation of diseases or disorders associated with the activity of potassium channels.
    Type: Application
    Filed: September 22, 2009
    Publication date: September 29, 2011
    Applicant: NEUROSEARCH A/S
    Inventors: Birgitte L. Eriksen, Charlotte Hougaard, Dan Peters, Palle Christophersen
  • PYRAZOLYL-PYRIMIDINE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS
    Publication number: 20110230484
    Abstract: This invention relates to novel pyrazolyl-pyrimidine derivatives and their use as potassium channel modulating agents. In another aspect the invention is directed to pharmaceutical compositions useful for the treatment or alleviation of diseases or disorders associated with the activity of potassium channels.
    Type: Application
    Filed: August 26, 2009
    Publication date: September 22, 2011
    Applicant: NEUROSEARCH A/S
    Inventors: Birgitte L. Eriksen, Charlotte Hougaard, Dan Peters, Palle Christophersen
  • Diphenylurea derivatives and their use as chloride channel blockers or BKchannel modulators
    Patent number: 7985761
    Abstract: The present invention relates to novel diphenylurea derivatives useful as chloride channel blockers or BKCa channel modulators. In other aspects the invention relates to the use of these compounds in a method for therapy, and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Grant
    Filed: March 9, 2007
    Date of Patent: July 26, 2011
    Assignee: Neurosearch A/S
    Inventors: Bjarne H. Dahl, Palle Christophersen, Lars Siim Madsen
  • 2-(phenylamino) benzimidazole derivatives and their use as modulators of small-conductance calcium-activated potassium channels
    Patent number: 7960561
    Abstract: This invention relates to novel 2-(phenylamino)benzimidazole derivatives useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Grant
    Filed: June 21, 2006
    Date of Patent: June 14, 2011
    Assignee: Neurosearch A/S
    Inventors: Ulrik Svane Sørensen, Lene Teuber, Dan Peters, Dorte Strøbæk, Tina Holm Johansen, Karin Sandager Nielsen, Palle Christophersen
  • CARBONYLAMINO DERIVATIVES USEFUL FOR THE TREATMENT OF CERTAIN INFLAMMATORY DISORDERS
    Publication number: 20110124735
    Abstract: The present invention relates to the use of a particular group of carbonylamino derivatives for the treatment or alleviation of a disease or condition relating to certain inflammatory disorders.
    Type: Application
    Filed: August 21, 2008
    Publication date: May 26, 2011
    Applicant: Neuro Search A/S
    Inventors: Lars Siim Madsen, Palle Christophersen
  • ERG CHANNEL OPENERS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS
    Publication number: 20110071164
    Abstract: This invention relates to the use of ERG channel openers for the treatment of cardiac arrhythmias, and to the use of specific compounds for such treatment. In a separate aspect the invention provides novel compounds useful as ERG channel openers.
    Type: Application
    Filed: November 9, 2010
    Publication date: March 24, 2011
    Inventors: Søren Peter OLESEN, Morten Grunnet, Palle Christophersen, Dorte STRØBÆK, Joachim Demnitz, Rie S. Hansen
  • NOVEL 2-AMINO BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS MODULATORS OF SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS
    Publication number: 20110034527
    Abstract: This invention relates to novel 2-amino benzimidazole derivatives useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: October 21, 2010
    Publication date: February 10, 2011
    Inventors: Ulrik Svane SØRENSEN, Lene Teuber, Dan Peters, Dorte Strøbæk, Tina Holm Johansen, Karin Sandager Nielsen, Palle Christophersen
  • ERG channel openers for the treatment of cardiac arrhythmias
    Patent number: 7851492
    Abstract: This invention relates to the use of ERG channel openers for the treatment of cardiac arrhythmias, and to the use of specific compounds for such treatment. In a separate aspect the invention provides novel compounds useful as ERG channel openers.
    Type: Grant
    Filed: September 6, 2004
    Date of Patent: December 14, 2010
    Assignee: Neurosearch A/S
    Inventors: Søren Peter Olesen, Morten Grunnet, Palle Christophersen, Dorte Strøbæk, Joachim Demnitz, Rie S. Hansen
  • 2-amino benzimidazole derivatives and their use as modulators of small-conductance calcium-activated potassium channels
    Patent number: 7842817
    Abstract: This invention relates to novel 2-amino benzimidazole derivatives useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Grant
    Filed: January 10, 2006
    Date of Patent: November 30, 2010
    Assignee: Neurosearch A/S
    Inventors: Ulrik Svane Sørensen, Lene Teuber, Dan Peters, Dorte Strøbæk, Tina Holm Johansen, Karin Sandager Nielsen, Palle Christophersen
  • PYRAZINE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS
    Publication number: 20100286161
    Abstract: This invention relates to novel pyrazine derivatives and their use as potassium channel modulating agents. Moreover the invention is directed to pharmaceutical compositions useful for the treatment or alleviation of diseases or disorders associated with the activity of potassium channels.
    Type: Application
    Filed: September 16, 2008
    Publication date: November 11, 2010
    Inventors: Birgitte L. Eriksen, Ulrik Svane Sørensen, Charlotte Hougaard, Dan Peters, Palle Christophersen
  • NOVEL 2-AMINO BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS MODULATORS OF SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS
    Publication number: 20100280087
    Abstract: This invention relates to novel 2-amino benzimidazole derivatives useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: July 8, 2010
    Publication date: November 4, 2010
    Inventors: Ulrik Svane Sørensen, Lene Teuber, Dan Peters, Dorte Strøbæk, Tina Holm Johansen, Karin Sandager Nielsen, Palle Christophersen
  • NOVEL 2, 3-DIAMINO-QUINAZOLINONE DERIVATIVES AND THEIR MEDICAL USE
    Publication number: 20100160315
    Abstract: This invention relates to novel 2,3-diamino-quinazolinone derivatives having medical utility, to use of the 2,3-diamino-quinazolinone derivatives of the invention for the manufacture of a medicament, to pharmaceutical compositions comprising the 2,3-diamino-quinazolinone derivatives of the invention, and to methods of treating a disorder, disease or a condition of a subject, which disorder, disease or condition is responsive to activation of Kv7 channels.
    Type: Application
    Filed: May 22, 2008
    Publication date: June 24, 2010
    Applicant: Neuro Search A/S
    Inventors: Carsten Jessen, William Dalby Brown, Joachim Demnitz, Dorte Strobaek, Mads P.G. Korsgaard, Palle Christophersen
  • PURINYL DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS
    Publication number: 20100152210
    Abstract: This invention relates to novel purinyl derivatives and their use as potassium channel modulating agents. Moreover the invention is directed to pharmaceutical compositions useful for the treatment or alleviation of diseases or disorders associated with the activity of potassium channels.
    Type: Application
    Filed: March 27, 2008
    Publication date: June 17, 2010
    Applicant: NEURO SEARCH A/S/
    Inventors: Birgitte L. Eriksen, Ulrik Svane Sørensen, Charlotte Hougaard, Dan Peters, Tina Holm Johansen, Palle Christophersen
  • 2-amino benzimidazole derivatives and their use as modulators of small-conductance calcium-activated potassium channels
    Patent number: 7737167
    Abstract: This invention relates to novel 2-amino benzimidazole derivatives useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Grant
    Filed: August 3, 2005
    Date of Patent: June 15, 2010
    Assignee: Neurosearch A/S
    Inventors: Ulrik Svane Sørensen, Lene Teuber, Dan Peters, Dorte Strøbæk, Tina Holm Johansen, Karin Sandager Nielsen, Palle Christophersen
  • NOVEL BENZAMIDINE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS
    Publication number: 20100144809
    Abstract: This invention relates to novel benzamidine derivatives of formula (I) that are found to be potent modulators of potassium channels and, as such, are valuable candidates for the treatment of diseases or disorders as diverse as those which are responsive to the modulation of potassium channels. A stereoisomer or a mixture of its stereoisomers, or an N-oxide thereof, or a pharmaceutically-acceptable addition salt thereof, wherein B may be absent (i.e. no heterocyclic ring is formed); and when absent, the nitrogen next to B holds a hydrogen (i.e. “NH”), and A represents NH2 or OH; or B may be present (i.e. forms part of a heterocyclic ring); and when present, B represents C?O or C?S; and A represents NH or O; and wherein the rest of variables are as specified in claim 1.
    Type: Application
    Filed: May 7, 2008
    Publication date: June 10, 2010
    Applicant: Neuro Search A/S
    Inventors: Antonio Nardi, Joachim Demnitz, Morten Grunnet, Palle Christophersen, David Spencer Jones, Elsebet Østergaard Nielsen, Dorte Strøbæk, Lars Siim Madsen