Patents by Inventor Palle Christophersen

Palle Christophersen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL BIPHENYL THIO-UREA DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS
    Publication number: 20100144736
    Abstract: The invention relates to novel biphenyl thio-urea derivatives of Formula (I), wherein A represents hydroxy or tetrazolyl; R1 represents halo, hydroxy or phenyl, which phenyl may optionally be substituted with halo; and R2 and R3, independent of each other, represent halo, trifluoromethyl, nitro and/or phenyl, that are found to be potent modulators of ion channels and, as such, they are valuable candidates for the treatment of disease or disorders as diverse as those which are responsive to modulation of ion channels.
    Type: Application
    Filed: December 17, 2007
    Publication date: June 10, 2010
    Applicant: NeuroSearch A/S
    Inventors: Antonio Nardi, Joachim Demnitz, Morten Grunnet, Palle Christophersen, David Spencer Jones, Elsebet Østergaard Nielsen, Dorte Strøbæk, Lars Siim Madsen
  • BETA-KETO-AMIDE DERIVATIVES USEFUL AS ION CHANNEL MODULATORS
    Publication number: 20100137387
    Abstract: This invention relates to novel ?-keto-amide derivatives that are found to be potent modulators of ion channels, and in particular potassium channels and chloride channels, and, as such, are valuable candidates for the treatment of diseases or disorders as diverse as those which are responsive to the modulation of potassium channels.
    Type: Application
    Filed: April 29, 2008
    Publication date: June 3, 2010
    Applicant: NeuroSearch A/S
    Inventors: Antonio Nardi, Jeppe Kejser Christensen, Morten Grunnet, Palle Christophersen, David Spencer Jones, Elsebet Østergaard Nielsen, Dorte Strøbæk, Lars Siim Madsen
  • NOVEL AROMATIC HETEROCYCLIC CARBOXYLIC ACID AMIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS
    Publication number: 20100137312
    Abstract: This invention relates to novel aromatic heterocyclic carboxylic acid amide derivatives of formula (I) that are found to be potent modulators of potassium channels and, as such, are valuable candidates for the treatment of diseases or disorders as diverse as those which are responsive to the modulation of potassium channels.
    Type: Application
    Filed: May 13, 2008
    Publication date: June 3, 2010
    Applicant: neuroSearch A/S
    Inventors: Antonio Nardi, Jeppe Kejser Christensen, Palle Christophersen, David Spencer Jones, Elsebet Østergaard Nielsen, Dorte Strøbæk, Lars Siim Madsen
  • ACETAMIDE DERIVATIVES AS POTASSIUM CHANNEL MODULATORS
    Publication number: 20100137381
    Abstract: This invention relates to novel acetamide derivatives that are found to be potent modulators of ion channels, in particular potassium channels and chloride channels, and, as such, are valuable candidates for the treatment of diseases or disorders as diverse as those which are responsive to the modulation of potassium channels.
    Type: Application
    Filed: April 29, 2008
    Publication date: June 3, 2010
    Applicant: NeuroSearch A/S
    Inventors: Antonio Nardi, Morten Grunnet, Palle Christophersen, Joachim Demnitz, David Spencer Jones, Elsebet Østergaard Nielsen, Dorte Strøbæk, Lars Siim Madsen
  • NOVEL SEMICARBAZIDE AND CARBONYLHYDRAZIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS
    Publication number: 20100137327
    Abstract: This invention relates to novel semicarbazide and carbonylhydrazide derivatives that are found to be potent modulators of potassium channels and, as such, they are valuable candidates for the treatment of diseases or disorders as diverse as those which are responsive to modulation of potassium channels.
    Type: Application
    Filed: January 17, 2008
    Publication date: June 3, 2010
    Applicant: NeuroSearch A/S
    Inventors: Antonio Nardi, Joachim Demnitz, Morten Grunnet, Palle Christophersen, David Spencer Jones, Elsebet Østergaard Nielsen, Dorte Strøbæk, Lars Siim Madsen
  • PURINYL DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS
    Publication number: 20100130516
    Abstract: This invention relates to novel purinyl derivatives and their use as potassium channel modulating agents. Moreover the invention is directed to pharmaceutical compositions useful for the treatment or alleviation of diseases or disorders associated with the activity of potassium channels.
    Type: Application
    Filed: March 27, 2008
    Publication date: May 27, 2010
    Applicant: NeuroSearch A/S
    Inventors: Birgitte L. Eriksen, Ulrik Svane Sørensen, Charlotte Hougaard, Dan Peters, Palle Christophersen
  • PURINYL DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS
    Publication number: 20100105705
    Abstract: This invention relates to novel purinyl derivatives and their use as potassium channel modulating agents. Moreover the invention is directed to pharmaceutical compositions useful for the treatment or alleviation of diseases or disorders associated with the activity of potassium channels.
    Type: Application
    Filed: March 27, 2008
    Publication date: April 29, 2010
    Applicant: NeuroSearch A/S
    Inventors: Birgitte L. Eriksen, Ulrik Svane, Charlotte Hougaard, Dan Peters, Tina Holm Johansen, Palle Christophersen
  • NOVEL 1,4- AND 1,5-DIARYLSUBSTITUTED 1,2,3-TRIAZOLES USEFUL AS POTASSIUM CHANNEL MODULATORS
    Publication number: 20100105689
    Abstract: This invention relates to novel 1,4- and 1,5-diarylsubstituted 1,2,3-triazole derivatives that are found to be potent modulators of potassium channels and, as such, they are valuable candidates for the treatment of diseases or disorders as diverse as those which are responsive to modulation of potassium channels.
    Type: Application
    Filed: January 17, 2008
    Publication date: April 29, 2010
    Inventors: Antonio Nardi, Morten Grunnet, Joachim Demnitz, Palle Christophersen, David Spencer Jones, Elsebet Østergaard Nielsen, Dorte Strøbæk, Lars Siim Madsen
  • MEDICAMENTS USEFUL AS POTASSIUM CHANNEL MODULATORS
    Publication number: 20100099732
    Abstract: This invention relates to pharmaceutical compositions comprising phenylcarbamoyl-methyl-indole derivatives that are found to be potent modulators of potassium channels and, as such, are valuable candidates for the treatment of diseases or disorders as diverse as those which are responsive to the modulation of potassium channels.
    Type: Application
    Filed: March 14, 2008
    Publication date: April 22, 2010
    Applicant: NeuroSearch A/S
    Inventors: Antonio Nardi, Morten Grunnet, Palle Christophersen, David Spencer Jones, Elsebet Østergaard Nielsen, Dorte Strøbaek, Lars Siim Madsen
  • NOVEL CINNAMIC AMIDE DERIVATIVES USEFUL AS ION CHANNEL MODULATORS
    Publication number: 20100087496
    Abstract: This invention relates to novel cinnamic amide derivatives that are found to be potent modulators of ion channels and, as such, they are valuable candidates for the treatment of diseases or disorders as diverse as those which are responsive to modulation of ion channels.
    Type: Application
    Filed: December 17, 2007
    Publication date: April 8, 2010
    Applicant: NeuroSearch A/S
    Inventors: Antonio Nardi, Morten Grunnet, Joachim Demnitz, Thomas Diness Jensen, Palle Christophersen, David Spencer Jones, Elsebet Ostergaard Nielsen, Dorte Strobaek, Lars Siim Madsen
  • Diphenylurea derivatives and their use as chloride channel blockers
    Patent number: 7691891
    Abstract: The present invention relates to novel diphenylurea derivatives useful as chloride channel blockers. In other aspects the invention relates to the use of these compounds in a method for therapy, and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Grant
    Filed: June 15, 2004
    Date of Patent: April 6, 2010
    Assignee: Neurosearch A/S
    Inventors: Bjarne H. Dahl, Palle Christophersen
  • NOVEL 2-AMINIO-PYRIDINE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS
    Publication number: 20100056584
    Abstract: This invention relates to novel 2-amino-pyridine derivative useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: November 12, 2007
    Publication date: March 4, 2010
    Applicant: NeuroSearch A/S
    Inventors: Ulrik Svane Sorensen, Birgitte L. Eriksen, Lene Teuber, Dan Peters, Dorte Strobaek, Tina Holm, Palle Christophersen
  • PYRIDINYL-PYRAZOLE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS
    Publication number: 20100035934
    Abstract: This invention relates to novel pyridinyl-pyrazole derivatives and their use as potassium channel modulating agents. Moreover the invention is directed to pharmaceutical compositions useful for the treatment or alleviation of diseases or disorders associated with the activity of potassium channels.
    Type: Application
    Filed: February 1, 2008
    Publication date: February 11, 2010
    Inventors: Birgitte L. Eriksen, Ulrik Svane Sørensen, Charlotte Hougaard, Lene Teuber, Dan Peters, Tina Holm Johansen, Palle Christophersen
  • NOVEL 4-AMINO-PYRIDINE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS
    Publication number: 20100035924
    Abstract: This invention relates to novel 4-amino-pyridine derivative useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: November 13, 2007
    Publication date: February 11, 2010
    Applicant: NeuroSearch A/S
    Inventors: Ulrik Svane Sørensen, Birgitte L. Eriksen, Lene Teuber, Dan Peters, Dorte Strøbæk, Tina Holm Johansen, Palle Christophersen
  • 2-AMINO BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS MODULATORS OF SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS
    Publication number: 20100035951
    Abstract: This invention relates to 2-amino benzimidazole derivatives of Formula 1a or 1b: which are useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: July 5, 2007
    Publication date: February 11, 2010
    Applicant: NEUROSEARCH A/S
    Inventors: Ulrik Svane Sørensen, Birgitte L. Eriksen, Lene Teuber, Dan Peters, Dorte Strøbaek, Tina Holm Johansen, Palle Christophersen
  • INDAZOLYL DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATING AGENTS
    Publication number: 20090325989
    Abstract: This invention relates to novel indazolyl derivatives useful as potassium channel modulating agents, and their use in the preparation of pharmaceutical compositions.
    Type: Application
    Filed: October 3, 2007
    Publication date: December 31, 2009
    Applicant: NEUROSEARCH A/S
    Inventors: Birgitte L. Eriksen, Ulrik Svane Sorensen, Charlotte Hougaard, Lene Teuber, Dan Peters, Palle Christophersen, Tina Holm Johansen
  • 2-PYRIDIN-2-YL-QUINAZOLINE DERIVATIVES AS POTASSIUM CHANNEL MODULATING AGENTS FOR THE TREATMENT OF RESPIRATORY DISEASES
    Publication number: 20090306102
    Abstract: This invention relates to novel pyridinyl-quinazoline derivatives and their use as potassium channel modulating agents. Moreover the invention is directed to pharmaceutical compositions useful for the treatment or alleviation of diseases or disorders associated with the activity of potassium channels.
    Type: Application
    Filed: December 18, 2006
    Publication date: December 10, 2009
    Inventors: Birgitte L. Eriksen, Ulrik Svane Sørensen, Lene Teuber, Dan Peters, Charlotte Hougaard, Tina Holm Johansen, Palle Christophersen
  • COMBINATIONS OF MONOAMINE REUPTAKE INHIBITORS AND POTASSIUM CHANNEL ACTIVATORS
    Publication number: 20090239880
    Abstract: This invention provides pharmaceutical compositions comprising therapeutically effective amounts of a monoamine reuptake inhibitor and an SK inhibitor. In another aspect the invention provides novel benzoimidazole derivatives for use according to the invention.
    Type: Application
    Filed: July 2, 2007
    Publication date: September 24, 2009
    Inventors: Ulrik Svane Sorensen, Birgitte L. Eriksen, Lene Teuber, Dan Peters, Dorte Strobaek, Tina Holm Johansen, Palle Christophersen, John Paul Redrobe
  • Novel Pyrimidine-2,4-Diamine Derivatives and their Use as Modulators of Small-Conductance Calcium-Activated Potassium Channels
    Publication number: 20090124645
    Abstract: This invention relates to novel pyrimidine-2,4-diamine derivatives useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: October 13, 2006
    Publication date: May 14, 2009
    Applicant: NeuroSearch A/S
    Inventors: Ulrik Svane Sorensen, Birgitte L. Eriksen, Lene Teuber, Dan Peters, Dorte Strobaek, Tina Holm Johansen, Palle Christophersen
  • NOVEL GUANIDINE DERIVATIVES AND THEIR MEDICAL USE
    Publication number: 20090099208
    Abstract: This invention relates to novel guanidine derivatives useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: March 22, 2007
    Publication date: April 16, 2009
    Inventors: Ulrik Svane Sorensen, Birgitte L. Eriksen, Lene Teuber, Dan Peters, Dorte Strobaek, Tina Holm Johansen, Palle Christophersen