Abstract: A social networking system predicts a life event (e.g., birthday, change in marital status, relationship status, etc.) for a target user based on information associated with the user. The social networking system identifies gift suggestions to provide to one or more friends of the user based on the predicted event. A gift suggestion may include an invitation to purchase or send an item, voucher, or other gift to the target user, wherein the gift may be determined based on information about the target user's interests obtained by the social networking system. The social networking system sends a gift suggestion to one or more friends of the target user, where the gift suggestion identifies the predicted life event and provides the gift suggestion to the target user's friend. The advertisement may require action by multiple of the target user's friends before the gift is sent to the target user.

Abstract: A system including variable parameter selection functionality operable for facilitating selection of a variable parameter of a composite query, parameter value assigning functionality operable for facilitating assignment to each parameter other than the variable parameter, one of the possible values associated therewith, composite query execution functionality operable, responsive to selection of the variable parameter and to assignment of the value to each parameter other than the variable parameter, for automatically executing the composite query for each possible value of the variable parameter, thereby being operable for receiving a multiplicity of composite query execution results corresponding to the multiplicity of possible values associated with the variable parameter, and composite query results display functionality operable, responsive to receiving the multiplicity of composite query execution results, for displaying, for each possible value associated with the variable parameter, a corresponding c

Abstract: The present invention relates to an insulin-like growth factor (IGF) receptor antagonist for use in the treatment of prostate neoplasia, including benign prostatic hyperplasia (BPH), prostate cancer, and particularly CRPC, wherein the antagonist is used in combination with an androgen receptor antagonist. An embodiment of the invention is where the androgen receptor antagonist is enzalutamide.

Abstract: The present invention is directed to a fuel cell system with various features for optimal operations of an electronic device, a battery charger or a fuel refilling device. The fuel cell system includes an information storage device associated with the fuel supply, pump and/or refilling device. The information storage device can be any electronic storage device including, but not limited to, an EEPROM or a PLA. The information storage device can include encrypted information. The information storage device can include software code for confirming the identification of the cartridge before operation of the electronic device and/or refilling device. The information storage device can include instructions for a hot swap operation to shut down properly when the fuel supply is ejected while the electronic device is in operation. The present invention is also directed to system architecture for a fuel cell system that utilizes information storage devices.

Abstract: The present invention relates to a binding molecule comprising a first and a second binding domain, wherein the first binding domain is capable of binding to epitope clusters of BCMA, and the second binding domain is capable of binding to the T cell CD3 receptor complex. Moreover, the invention provides a nucleic acid sequence encoding the binding molecule, a vector comprising said nucleic acid sequence and a host cell transformed or transfected with said vector. Furthermore, the invention provides a process for the production of the binding molecule of the invention, a medical use of said binding molecule and a kit comprising said binding molecule.

Abstract: A process for preparing torrefied densified biomass and/or torrefied densified biosolids comprising about 2% to about 25% w/w combustible liquid is disclosed. The process involves densifying biomass and/or biosolids, or providing a densified biomass and/or densified biosolids, and submerging the densified material in a hot combustible liquid for about 2 to about 120 minutes until the densified material is torrefied. The combustible liquid may be derived from any source exemplified by an oil such as those derived from plant, marine and animal sources, or alternatively, a petroleum product. The combustible liquid is heated to a temperature in the range of about 160° C. to about 320° C. prior to submersion of the densified biomass material. Also disclosed is a biomass torrefied densified biomass and/or torrefied densified biosolid comprising about 2% to about 25% w/w combustible liquid.

Abstract: The present invention relates to a binding molecule which is at least bispecific comprising a first and a second binding domain, wherein the first binding domain is capable of binding to epitope cluster 3 of BCMA, and the second binding domain is capable of binding to the T cell CD3 receptor complex. Moreover, the invention provides a nucleic acid sequence encoding the binding molecule, a vector comprising said nucleic acid sequence and a host cell transformed or transfected with said vector. Furthermore, the invention provides a process for the production of the binding molecule of the invention, a medical use of said binding molecule and a kit comprising said binding molecule.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for transmitting contact data for displaying graphical representations of contacts for display to a user, the contacts being contacts of the user within a computer-implemented social networking service, generating a first social circle of the user, the first social circle comprising a first subset of contacts of the user within the social networking service and defining a first distribution for digital content, generating a second social circle of the user, the second social circle comprising a second subset of contacts of the user within the social networking service and defining a second distribution for digital content, and, in response to user input, providing the first social circle and the second social circle for selection by the user to define a distribution of digital content, the distribution comprising at least one of the first distribution and the second distribution.

Abstract: A cosmetic container for housing a cosmetic product applicator is presented. The cosmetic container comprises: a cosmetic product applicator; a tubular housing comprising first and second portions; and a platform positioned within the tubular housing and connected to the first portion of the housing, the platform being adapted to receive the cosmetic product applicator inserted into the tubular housing. The first portion of the housing is rotatable relative to the second portion of the housing about an axis of rotation so as to move the platform between a first position, in which substantially the entire length of the cosmetic product applicator is situated within the tubular housing so as to prevent its removal from the housing, and a second position, in which a portion of the cosmetic applicator projects outwardly from the tubular housing so as to permit its removal from the housing.

Abstract: A gas-generating apparatus includes a cartridge including a reservoir having a first reactant and a reaction chamber, and a receiver that can include a flow control device. The receiver is adapted to receive the cartridge and to transport the first reactant to the reaction chamber after connection with the cartridge. The flow control device is adapted to stop the transport of reactant when the pressure in the reaction chamber reaches a predetermined pressure.

Abstract: A squeegee device is provided that includes a blade support and a deflector. The blade support has a front support and a rear support, which are configured to secure a squeegee blade therebetween. The deflector has a lower portion and an upper portion, which are configured so that the lower portion of the deflector depends upward from the blade support and a leading edge of the upper portion is forward, with respect to a pushing direction, from the blade support.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for receiving first user input, the first user input provided by a user of a computer-implemented social networking service and indicating first digital content that is to be distributed using the social networking service, receiving second user input through a distribution interface that is displayed to the user, the second user input defining a distribution for the first digital content, the distribution comprising at least one of a first sub-distribution that is defined based on a first social circle and a second sub-distribution, the first social circle comprising a first subset of contacts, and distributing the first digital content to contacts of the user based on the distribution.

Abstract: A cleaning cart is provided that includes a base, a plurality of wheels and a storage region depending from the base, and a bucket restraining device. The base has a first side wall, a second side wall, and a front wall, the base having at least one portion configured to receive a bucket thereon. The bucket restraining device has a lateral restraining wall and a rear restraining wall that cooperate to define a first restraining region and a second restraining region. The first restraining region is defined by the first side wall, the front wall, the lateral restraining wall, and a portion of the rear restraining wall. The second restraining region is defined by the second side wall, the front wall, the lateral restraining wall, and a different portion of rear restraining wall.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for transmitting contact data for displaying representations of contacts for display to a user, the contacts being contacts of the user within a computer-implemented social networking service, generating a first social circle of the user, the first social circle comprising a first subset of contacts of the user within the social networking service and defining a first distribution for digital content, generating a second social circle of the user, the second social circle comprising a second subset of contacts of the user within the social networking service and defining a second distribution for digital content, and, in response to user input, providing the first social circle and the second social circle for selection by the user to define a distribution of digital content, the distribution comprising at least one of the first distribution and the second distribution.

Abstract: A shut-off valve or connecting valve capable of connecting a fuel supply to a fuel cell is disclosed. The valve comprises a first valve component and a second valve component. Each valve component has an outer housing and a biased slidable member disposed inside the housing forming an internal seal. During the connection process, the two valve components establish an inter-component seal. Afterward, in one suitable embodiment the slidable member moves inward and opens the internal seal in the valve component to establish a flow path. In another embodiment, the slidable member moves inward and exposes a first filler and the first filler abuts a second filler in the other valve component to establish a flow path. In other embodiments, at least one valve component is sized and dimensioned to limit access to the internal seal.

Abstract: A cleaning cart is provided that includes a base, a plurality of wheels and a storage region depending from the base, and a bucket restraining device. The base has a first side wall, a second side wall, and a front wall, the base having at least one portion configured to receive a bucket thereon. The bucket restraining device has a lateral restraining wall and a rear restraining wall that cooperate to define a first restraining region and a second restraining region. The first restraining region is defined by the first side wall, the front wall, the lateral restraining wall, and a portion of the rear restraining wall. The second restraining region is defined by the second side wall, the front wall, the lateral restraining wall, and a different portion of rear restraining wall.

Abstract: Modular pure water systems are provided that have a tank and a cover assembly, wherein the tank and cover assembly are configured to removably receive therebetween one or more expansion tubes in a fluid tight manner to allow for selective volume expansion of the pure water system. Also provided are purification media bags for pure water systems that have a shape, construction, and/or material that mitigates the flow of water between the outer wall of the bag and an inner wall of the pure water systems.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for transmitting contact data for displaying graphical representations of contacts for display to a user, the contacts being contacts of the user within a computer-implemented social networking service, generating a first social circle of the user, the first social circle comprising a first subset of contacts of the user within the social networking service and defining a first distribution for digital content, generating a second social circle of the user, the second social circle comprising a second subset of contacts of the user within the social networking service and defining a second distribution for digital content, and, in response to user input, providing the first social circle and the second social circle for selection by the user to define a distribution of digital content, the distribution comprising at least one of the first distribution and the second distribution.