Abstract: Presented are automated driving systems for intelligent vehicle control, methods for making/using such systems, and motor vehicles equipped with such automated driving systems. A method for executing an automated driving operation includes: determining path plan data for a subject motor vehicle, including current vehicle location and predicted route data; receiving, from a network of sensing devices, sensor data indicative of current object position and object dynamics of a target object; applying sensor fusion techniques to the received sensor data to determine a threat confidence value that is predictive of target object intrusion with respect to the vehicle's location and predicted route; determining if this threat confidence value is greater than a calibrated threshold value; and, responsive to the threat confidence value being greater than the calibrated threshold value, transmitting one or more command signals to one or more vehicle systems (e.g.

Abstract: A social networking system predicts a life event (e.g., birthday, change in marital status, relationship status, etc.) for a target user based on information associated with the user. The social networking system identifies gift suggestions to provide to one or more friends of the user based on the predicted event. A gift suggestion may include an invitation to purchase or send an item, voucher, or other gift to the target user, wherein the gift may be determined based on information about the target user's interests obtained by the social networking system. The social networking system sends a gift suggestion to one or more friends of the target user, where the gift suggestion identifies the predicted life event and provides the gift suggestion to the target user's friend. The advertisement may require action by multiple of the target user's friends before the gift is sent to the target user.

Abstract: A system according to the principles of the present disclosure includes a current object position module, an expected position module, and an object position comparison module. The current object position module can determine a first position of an object with respect to a position of a vehicle based upon sensor data generated by a first object detection sensor within the vehicle and determines a second position of the object with respect to the position of the vehicle based upon sensor data generated by a second object detection sensor. The expected object position module can determine an expected position of the object with respect to the position of the vehicle based upon the first position of the object. The object position comparison module can determine whether at least one object detection sensor is improperly installed within the vehicle based upon comparing the second position of the object with the expected position.

Abstract: Modular pure water systems are provided that have a tank and a cover assembly, wherein the tank and cover assembly are configured to removably receive therebetween one or more expansion tubes in a fluid tight manner to allow for selective volume expansion of the pure water system. Also provided are purification media bags for pure water systems that have a shape, construction, and/or material that mitigates the flow of water between the outer wall of the bag and an inner wall of the pure water systems.

Abstract: The present invention relates to immunotherapies that are based on myeloid cell depletion. In particular, the present invention relates to CD33 binding agents for use in such therapies, e.g. in the treatment of myeloid cell malignancies and myelodysplastic syndrome (MDS).

Abstract: The present invention relates to an insulin-like growth factor (IGF) receptor antagonist for use in the treatment of prostate neoplasia, including benign prostatic hyperplasia (BPH), prostate cancer, and particularly CRPC, wherein the antagonist is used in combination with an androgen receptor antagonist. An embodiment of the invention is where the androgen receptor antagonist is enzalutamide.

Abstract: In an aspect, a wear plate for use with a conveyor system is provided. The wear plate has a plate mount, having a fastener retainer having a retention hole extending through the wear plate, and a retainer support being defined by at least one cut in the wear plate adjacent to and at least partially defining the fastener retainer, the retainer support connecting the fastener retainer to a main portion of the wear plate and enabling the fastener support to be depressed relative to a top surface of the wear plate.

Abstract: Antibody molecules, in particular fully human antibodies that bind to human IGF-1 and cross-react with IGF-2 such that binding of IGF-1 and IGF-2 to the IGF-1 receptor is prevented and IGF-1 receptor-mediated signaling is inhibited. The antibodies do not bind to insulin and thus do not affect the mitogenic properties of insulin that are mediated by its binding to the insulin receptors. The antibodies are useful for the treatment of hyperproliferative diseases, in particular cancer.

Abstract: An apparatus for rotating an inner stamped part with respect to an outer stamped part is provided. The inner stamped part is nested within an aperture formed within the outer stamped part. The apparatus includes a plurality of grippers that include at least a first gripper positioned at a first edge of the inner stamped part and a second gripper positioned at a second edge of the inner stamped part opposite to the first edge. The plurality of grippers is configured to grip the inner stamped part at the first edge and the second edge, respectively. The plurality of grippers is further configured to rotate the gripped inner stamped part about an axis of rotation. The axis of rotation intersects the first gripper and the second gripper. The plurality of grippers is also configured to open to release the inner stamped part.

Abstract: A rotary airless compact including facing concentric arcuate inner and annular outer walls which are manually rotatable relative to each other, and a flexible tube extending between the walls and secured to the inner wall. The outer wall has radial ribs projecting inwardly to crimp the tube at spaced locations against the inner wall, providing successive seals between which the tube has internally open regions for holding fluid product. As the outer wall rotates relative to the inner wall in a direction from a first to a second end of the tube, product is drawn from a supply pouch at the first end into successive open regions of the tube in discrete quantities separated by the seals, and the ribs advance the seals and open regions to the second end, where a nozzle or other dispensing element discharges the quantities of product into a pan area of the compact.

Abstract: A system according to the present disclosure includes a lane boundary module, a vehicle trajectory module, an intersection location module, a lane departure module, and a driver warning module. The lane boundary module is configured to determine a boundary of a lane within which a vehicle is travelling. The vehicle trajectory module is configured to predict a trajectory of the vehicle. The intersection location module is configured to determine M locations of M intersections between the vehicle trajectory and the lane boundary at M times, where M is an integer greater than one. The lane departure module is configured to identify a potential lane departure based on the M locations. The driver warning module is configured to activate a driver warning device to warn a driver when the potential lane departure is identified.

Abstract: In an aspect, a conveyor system for moving a wheeled structure through a service line is provided. The conveyor system comprises at least one endless belt mounted longitudinally through the service line. The belt has an upper transport portion for moving the vehicle through the service line, and a lower return portion with a support deck below the upper transport portion to support the belt. A debris deflector is mounted between the upper transport portion and the lower return portion to protect the lower return portion from debris falling through the support deck.

Abstract: A system for a vehicle operating on a road includes a vehicle placement module that references, based on a geographic position of the vehicle, a road mapping database to identify a selected lane of the road where the vehicle is located. A lane assignment module (i) receives information indicating identification of an object in the road and (ii) determines a relative lane of the object with respect to the selected lane. A curvature plotting module determines a curvature line of the selected lane. An object placement module (i) determines a first distance value representing a shortest distance between the object and the curvature line and (ii) determines whether the relative lane of the object is the selected lane based on the first distance value and a lane width value. An alert generation module selectively generates an alert signal in response to the object being in the selected lane.

Abstract: A system for a vehicle operating on a road includes a vehicle placement module that references, based on a geographic position of the vehicle, a road mapping database to identify a selected lane of the road where the vehicle is located. A lane assignment module (i) receives information indicating identification of an object in the road and (ii) determines a relative lane of the object with respect to the selected lane. A curvature plotting module determines a curvature line of the selected lane. An object placement module (i) determines a first distance value representing a shortest distance between the object and the curvature line and (ii) determines whether the relative lane of the object is the selected lane based on the first distance value and a lane width value. An alert generation module selectively generates an alert signal in response to the object being in the selected lane.

Abstract: An automotive vehicle includes a propulsion system, at least one wheel brake, a sensor configured to detect objects external to the vehicle, and a controller. The controller is configured to, in response to the sensor detecting a first target vehicle in the path of the host vehicle and a second target vehicle in the path of the host vehicle, automatically control the propulsion system and the at least one wheel brake based on a first relative velocity associated with the first target vehicle, a first relative acceleration associated with the first target vehicle, a second relative velocity associated with the second target vehicle, and a second relative acceleration associated with the second target vehicle.

Abstract: Embodiments described herein are related to performing virtual application delivery. In some embodiments, a method includes accessing, at a computing device, a datastore comprising a first virtual disk file mapped to a plurality of virtual disk files separate from the first virtual disk file, wherein each of the plurality of virtual disk files comprises at least one application stored thereon. The method further includes receiving, at the computing device, one or more operations for accessing the first virtual disk file, the one or more operations corresponding to a first application stored on a second virtual disk file of the plurality of virtual disk files. The method further includes redirecting the one or more operations for accessing the first virtual disk file to the second virtual disk file.

Abstract: The present invention relates to immunotherapies that are based on myeloid cell depletion. In particular, the present invention relates to CD33 binding agents for use in such therapies, e.g. in the treatment of myeloid cell malignancies and myelodysplastic syndrome (MDS).

Abstract: Antibody molecules, in particular fully human antibodies that bind to human IGF-1 and cross-react with IGF-2 such that binding of IGF-1 and IGF-2 to the IGF-1 receptor is prevented and IGF-1 receptor-mediated signaling is inhibited. The antibodies do not bind to insulin and thus do not affect the mitogenic properties of insulin that are mediated by its binding to the insulin receptors. The antibodies are useful for the treatment of hyperproliferative diseases, in particular cancer.

Abstract: A cleaning device for use with a cleaning fabric is provided. The device includes a plate, a connection member, a plurality of fingers, a wiper assembly, and a grip. The plate has a first side and a second side. The connection member retains the cleaning fabric to the plate. The fingers depend from the first side and provide a gap between the first side and the cleaning fabric during use. The wiper assembly has at least one elongated wiper blade that divides the fingers into a front section and a rear section. The grip depends from the second side.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for transmitting contact data for displaying representations of contacts for display to a user, the contacts being contacts of the user within a computer-implemented social networking service, generating a first social circle of the user, the first social circle comprising a first subset of contacts of the user within the social networking service and defining a first distribution for digital content, generating a second social circle of the user, the second social circle comprising a second subset of contacts of the user within the social networking service and defining a second distribution for digital content, and, in response to user input, providing the first social circle and the second social circle for selection by the user to define a distribution of digital content, the distribution comprising at least one of the first distribution and the second distribution.