Abstract: The present disclosure provides certain 3H,4H-thieno[2,3-d]pyrimidin-4-one derivatives that are inhibitors of transient receptor potential ankyrin 1 (TRPA1), and are therefore useful for the treatment of diseases treatable by inhibition of TRPA1. Also provided are pharmaceutical compositions containing the same, and processes for preparing said compounds.

Abstract: The present disclosure provides certain uracil derivatives that are inhibitors of transient receptor potential ankyrin 1 (TRPA1), and are therefore useful for the treatment of diseases treatable by inhibition of TRPA1. Also provided are pharmaceutical compositions containing the same, and processes for preparing said compounds.

Abstract: The present disclosure provides certain imidazo[4,5-d]pyridazinonyl derivatives that are inhibitors of transient receptor potential ankyrin 1 (TRPA1), and are therefore useful for the treatment of diseases treatable by inhibition of TRPA1. Also provided are pharmaceutical compositions containing the same, and processes for preparing said compounds.

Abstract: The present disclosure provides certain 3H,4H,5H,6H,7H-pyrimido[4,5-b][1,4]oxazine-4,6-dione derivatives that are inhibitors of transient receptor potential ankyrin 1 (TRPA1), and are therefore useful for the treatment of diseases treatable by inhibition of TRPA1. Also provided are pharmaceutical compositions containing the same, and processes for preparing said compounds.

Abstract: Systems, apparatuses, and methods provides for technology that controls a confocal antenna system. The technology controls an Integrated Phased Array (IPA) feed system to emit electromagnetic energy towards a sub-reflector, where the sub-reflector reflects the electromagnetic energy to a main reflector, and further where the main reflector receives and reflects the electromagnetic energy to form a radiation pattern on an area. The radiation pattern has a first size and a first gain. The technology conducts an identification that the radiation pattern is to be adjusted so as to adjust the first size to a second size and adjust the first gain to a second gain. In response to the identification, the technology moves the main reflector linearly along a first axis, and electronically steers a beam of the electromagnetic energy emitted from the IPA feed system towards the sub-reflector.

Abstract: A fire control lockout assembly restricts a semiautomatic style firearm to single shot operation by requiring specific, sequential manual manipulation of the firearm by the operator prior to firing a subsequent round from the firearm. The lockout assembly has a modified safety selector and a modified disconnector and/or a modified trigger assembly that interrupts the usual automatic progression of the fire control group components after firing the firearm by increasing the upward distance the trigger sear must travel before contacting the disconnector. The increased distance prevents the hammer from automatically being released from the disconnector. The modified safety selector has a barrel that presses downward on the rearward end of the disconnector to release the hammer. After firing a round, the safety selector must be moved to its safe position and then to its fire position in order to fire a subsequent round from the firearm.

Abstract: Provided are methods of preparing an electrochemically active cathode material including the steps of (a) combining an alkali metal-containing layered nickel oxide having a formula A1?aNi1+aO2, wherein A comprises an alkali metal and 0<a?0.2, with an oxidant comprising a peroxydisulfate salt and/or a monopersulfate salt to form a mixture, (b) heating the mixture to form a Ni(IV) containing mixture including a Ni(IV) containing electrochemically active cathode material; (c) adding to the Ni(IV) containing mixture of step (b) a mineral acid; and (d) heating the mixture of step (c) to form an additional amount of the Ni(IV) containing electrochemically active cathode material, the Ni(IV) containing electrochemically active cathode material formed in steps (b) and (d) having a general formula AxHyNi1+aO2, wherein A comprises an alkali metal; 0.08?x<0.2; 0?y<0.3; and 0.02?a?0.2.

Abstract: A nip guard (10) for use with a conveyor system which includes a pulley (84) and a flexible conveyor belt (88) which is engaged with and which passes over the pulley (84), the conveyor belt (88) including an outer load-carrying surface (82) and an inner surface (86), wherein the nip guard (10) includes supporting structure (64, 66, 60) and, mounted to the supporting structure (60, 64, 66), at least one belt scraping element (46) configured to be in scraping contact with the inner surface (86) of the belt (88).

Abstract: This invention relates to novel (Cyano-dimethyl-methyl)-isoxazoles and -[1,3,4]thiadiazoles and their use as CB2 cannabinoid receptor agonists, pharmaceutical compositions containing the same, and their use for the treatment of CB2 receptor mediated disorders or conditions.

Abstract: The present disclosure provides certain tetrazole derivatives that are inhibitors of transient receptor potential ankyrin 1 (TRPA1), and are therefore useful for the treatment of diseases treatable by inhibition of TRPA1. Also provided are pharmaceutical compositions containing the same, and processes for preparing said compounds.

Abstract: The present disclosure provides certain tetrazole derivatives that are inhibitors of transient receptor potential ankyrin 1 (TRPA1), and are therefore useful for the treatment of diseases treatable by inhibition of TRPA1. Also provided are pharmaceutical compositions containing the same, and processes for preparing said compounds.

Abstract: Solid rinsing, cleaning and/or sanitizing compositions for various applications are provided. In particular, solid compositions include a complex of urea and an acid having desirable storage stability previously unavailable in solid urea/acid compositions. Stable solid compositions are disclosed and methods of making the same to overcome conventional limitations associated with with forming kinetically and thermodynamically stable solids that utilize urea/acid compositions.

Abstract: Compact lens systems that may be used in small form factor cameras. The lens system may include a master lens with two or more lens elements arranged along an optical axis and having refractive power, and an optical actuator located on the object side of the master lens that may provide autofocus (AF) and/or optical image stabilization (OIS) functionality for the camera. An aperture stop for the camera may be included in the optical actuator, for example between a substrate and a flexible optical element of the optical actuator. Including the aperture stop in the optical actuator rather than in the lens stack may allow the optical actuator to be smaller in the X-Y dimensions (perpendicular to the optical (Z) axis) than it would be in a similar camera with the aperture stop located in the lens stack.

Abstract: The present disclosure provides certain tetrazole derivatives that are inhibitors of transient receptor potential ankyrin 1 (TRPA1), and are therefore useful for the treatment of diseases treatable by inhibition of TRPA1. Also provided are pharmaceutical compositions containing the same, and processes for preparing said compounds.

Abstract: The present disclosure provides certain tetrazole derivatives that are inhibitors of transient receptor potential ankyrin 1 (TRPA1), and are therefore useful for the treatment of diseases treatable by inhibition of TRPA1. Also provided are pharmaceutical compositions containing the same, and processes for preparing said compounds.

Abstract: This invention relates to thienopyrimidinones and their use as inhibitors of TRPA1 activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of fibrotic diseases, inflammatory and auto-immune diseases and CNS-related diseases.

Abstract: Solid rinsing, cleaning and/or sanitizing compositions for various applications are provided. In particular, solid compositions include a complex of urea and an acid having desireable storage stability previously unavailable in solid urea/acid compositions. Stable solid compositions are disclosed and methods of making the same to overcome conventional limitations associated with with forming kinetically and thermodynamically stable solids that utilize urea/acid compositions.

Abstract: Compact lens systems that may be used in small form factor cameras. The lens system may include a master lens with two or more lens elements arranged along an optical axis and having refractive power, and an optical actuator located on the object side of the master lens that may provide autofocus (AF) and/or optical image stabilization (OIS) functionality for the camera. An aperture stop for the camera may be included in the optical actuator, for example between a substrate and a flexible optical element of the optical actuator. Including the aperture stop in the optical actuator rather than in the lens stack may allow the optical actuator to be smaller in the X-Y dimensions (perpendicular to the optical (Z) axis) than it would be in a similar camera with the aperture stop located in the lens stack.

Abstract: This invention relates to thienopyrimidinones and their use as inhibitors of TRPA1 activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of fibrotic diseases, inflammatory and auto-immune diseases and CNS-related diseases.

Abstract: This invention relates to novel (Cyano-dimethyl-methyl)-isoxazoles and -[1,3,4]thiadiazoles and their use as CB2 cannabinoid receptor agonists, pharmaceutical compositions containing the same, and their use for the treatment of CB2 receptor mediated disorders or conditions.