Abstract: The level of exosomal polypeptides in a sample from a patient who has received a transplant is assayed and used as an indicator for transplant rejection. Based on the measured level of the exosomal polypeptides, therapeutic intervention, such as an immunosuppressant therapy, may be started, adjusted, continued or discontinued.

Abstract: This invention relates to novel (Cyano-dimethyl-methyl)-isoxazoles and -[1,3,4]thiadiazoles and their use as CB2 cannabinoid receptor agonists, pharmaceutical compositions containing the same, and their use for the treatment of CB2 receptor mediated disorders or conditions.

Abstract: Solid rinsing, cleaning and/or sanitizing compositions for various applications are provided. In particular, solid compositions include a complex of urea and an acid having desireable storage stability previously unavailable in solid urea/acid compositions. Stable solid compositions are disclosed and methods of making the same to overcome conventional limitations associated with with forming kinetically and thermodynamically stable solids that utilize urea/acid compositions.

Abstract: A conveyor belt scraper (44) which has a moulded base (10), a scraper element (46) which is moulded to the base (10), and resiliently compressible inserts (80, 82) between relatively movable opposed surfaces of the base (10) and the scraper element (46).

Abstract: A conveyor belt scraper (40) which includes a base (10) and a scraper element (42) which is moulded to the base (10).

Abstract: A multimodal biometric authentication system utilizes a bulk absorption characteristic of human tissue that is measurable using a photoplethysmography (PPG) sensor. One disclosed method of operation includes extracting bulk absorption features from biometric data obtained using a PPG sensor and generating a first biometric template. Additional biometric features are also extracted from biometric data obtained using a second biometric sensor and a second biometric template is also generated. An authentication output signal is provided in response to the first biometric template matching a first enrolled biometric template and the second biometric template matching a second enrolled biometric template.

Abstract: An automated system and method provides for planning and response to disparate threats with combined kinetic (e.g., missile interceptor) and non-kinetic (e.g., cyber and electronic warfare) effects. The threat and effects inputs and the results of analysis tools that individually apply a single effect type to negate a threat vulnerability are normalized to a form and format ingestible by a Stochastic Math Model (SMM). The normalized inputs reflect the success/failure of the effect versus a threat vulnerability as a score, not a probability. The normalized results decompose a probability of defeat (Pdefeat) for an individual effect as a set of hierarchical parameters represented as probabilities.

Abstract: Alkaline sprayable aqueous compositions for cleaning, sanitizing and disinfecting are disclosed. In particular, the sprayable compositions include an inverse emulsion polymer for modifying the viscosity of the composition and provide numerous benefits over dispersion polymer compositions used for rheology modification to reduce misting and respiratory inhalation of cleaning compositions. Compositions and methods of cleaning using the compositions having reduced amounts of airborne particulates of the composition during spray applications are provided.

Abstract: Acidic sprayable aqueous compositions for cleaning, sanitizing and disinfecting are disclosed. In particular, the sprayable compositions include an inverse emulsion polymer for modifying the viscosity of the composition and provide numerous benefits over dispersion polymer compositions used for rheology modification to reduce misting and respiratory inhalation of cleaning compositions. Compositions and methods of cleaning using the compositions having reduced amounts of airborne particulates of the composition during spray applications are provided.

Abstract: This invention relates to novel (Cyano-dimethyl-methyl)-isoxazoles and -[1,3,4]thiadiazoles and their use as CB2 cannabinoid receptor agonists, pharmaceutical compositions containing the same, and their use for the treatment of CB2 receptor mediated disorders or conditions.

Abstract: A multimodal biometric authentication system utilizes a bulk absorption characteristic of human tissue that is measurable using a photoplethysmography (PPG) sensor. One disclosed method of operation includes extracting bulk absorption features from biometric data obtained using a PPG sensor and generating a first biometric template. Additional biometric features are also extracted from biometric data obtained using a second biometric sensor and a second biometric template is also generated. An authentication output signal is provided in response to the first biometric template matching a first stored corresponding enrolled biometric template and the second biometric template matching a second stored corresponding enrolled biometric template.

Abstract: A multimodal biometric authentication system utilizes a bulk absorption characteristic of human tissue that is measurable using a photoplethysmography (PPG) sensor. One disclosed method of operation includes extracting bulk absorption features from biometric data obtained using a PPG sensor and generating a first biometric template. Additional biometric features are also extracted from biometric data obtained using a second biometric sensor and a second biometric template is also generated. An authentication output signal is provided in response to the first biometric template matching a first enrolled biometric template and the second biometric template matching a second enrolled biometric template.

Abstract: This invention relates to novel (Cyano-dimethyl-methyl)-isoxazolesand-[1,3,4]thiadiazoles and their use as CB2 cannabinoid receptor agonists, pharmaceutical compositions containing the same, and their use for the treatment of CB2 receptor mediated disorders or conditions.

Abstract: A primary battery includes a cathode having an alkali-deficient nickel oxide including metals such as Ca, Mg, Al, Co, Y, Mn, and/or non-metals such as B, Si, Ge, or a combination of metal and/or non-metal atoms; a combination of metal atoms; an anode; a separator between the cathode and the anode; and an alkaline electrolyte.

Abstract: The level of miRNAs in a sample from a patient is assayed and used as an indicator of the efficacy of a therapeutic intervention for a cardiovascular disease, such as heart failure. The levels of a plurality of miRNAs, such as myomirs, may be measured. Based on the measured level of the miRNAs, the therapeutic intervention may be modified, adjusted, continued or discontinued. The miRNA level may also be used to assess the severity or disease progression of a cardiovascular disease.

Abstract: The level of miRNAs in a sample from a patient who has received a transplant is assayed and used as an indicator for transplant rejection. Based on the measured level of the miRNAs, therapeutic intervention, such as an immunosuppressant therapy, may be started, adjusted, continued or discontinued.

Abstract: This invention relates to novel (Cyano-dimethyl-methyl)-isoxazolesand-[1,3,4]thiadiazoles and their use as CB2 cannabinoid receptor agonists, pharmaceutical compositions containing the same, and their use for the treatment of CB2 receptor mediated disorders or conditions.

Abstract: A gasification reactor including a gasifier having a tubular gastight wall with a discharge channel or dip tube at its lower end leading into a lower slag collection bath. The gastight wall and the slag collection bath are arranged within a pressure vessel. An annular space between the pressure vessel and the gasifier with the discharge channel is separated in a high pressure top section and a low pressure lower section by a sealing arrangement having a damper. The damper can for instance be a hydraulic lock, or a lower seal at a distance below an upper seal.

Abstract: Methods and systems for accessing documents in document collections using predictive word sequences are disclosed. A method for accessing documents using predictive word sequences include creating a candidate list of word sequences where respective ones of the word sequences comprise one or more elements derived from the document corpus; expanding the candidate list by adding one or more new word sequences, where each new pattern is created by combining one or more elements derived from the document corpus with one of the word sequences currently in the candidate list; determining a predictive power with respect to the subject for respective ones of entries of the candidate list, where the entries include the word sequences and the new word sequences; pruning from the candidate list ones of said entries with the determined predictive power less than a predetermined threshold; and accessing documents from the document corpus based on the pruned candidate list.

Abstract: Methods of making high-energy cathode active materials for primary alkaline batteries are described. The primary batteries include a cathode having an alkali-deficient nickel(IV)-containing oxide including one or more metals such as Co, Mg, Al, Ca, Y, Mn, and/or non-metals such as B, Si, Ge or a combination of metal and/or non-metal atoms as dopants partially substituted for Ni and/or Li in the crystal lattice; an anode; a separator between the cathode and the anode; and an alkaline electrolyte solution.