Abstract: It is the object of the present invention to provide a new polymer coating for low temperature plastics and plastic foams that allows for the application of disperse dyes in a sublimation process that preserves the original properties of the underlying plastic substrate. The composition includes an optically clear synthetic organic polymer base holding two layers, a first reflective layer supported by the low temperature plastic substrate that includes IR radiation reflecting additives, and a second layer supported by the first layer having light scattering particulate additives. The disperse dyes utilized in the invention may include additives to absorb IR radiation provided by an external IR source positioned above the disperse dyes causing the dyes to sublimate and diffuse quickly into the light scattering layer. The combination of these layers allows for diffusion of the disperse dye ink into the light scattering layer while protecting the low temperature plastic below.

Abstract: An aerosol delivery device is disclosed. The aerosol delivery device includes an atomizer and a body. The body has an outlet and houses the atomizer. The aerosol delivery device also includes a structure configured to inhibit liquid droplets of an aerosol precursor from exiting the outlet. Embodiments of the structure include micro-patterned surfaces, absorbers, and macro structures to create droplet capturing chambers.

Abstract: Provided are chemically modified tetracycline (CMT) derivatives for the treatment of non-exudative macular degeneration. The CMT derivatives lack antimicrobial activity, include a phenol ring, and a chemical structure sufficient to chelate Zn2+. Methods of inhibiting and/or minimizing inflammation in a subject, including administering to the subject a dose of a CMT derivative, are also provided. Methods of treating non-exudative age-related macular degeneration (AMD) are provided.

Abstract: There is described a device, such as a wireholder, for measuring a load of an elongate member, such as a power line. The device includes a body, a load-bearing member, and a first sensor operable to measure a load applied to the load-bearing member in a first direction, for example a direction of sensitivity defined by the first sensor. The load-bearing member is movably coupled to the body such that the load-bearing member is displaced from a reference position as a function of a load applied to the load-bearing member in a second direction, such as a direction normal to the first direction. The device may further include a second sensor for measuring a displacement of the load-bearing member.

Abstract: The disclosure is directed to methods of treating cancer in subjects with a combination of a monoclonal antibody and (R)-N-(4-chlorophenyl)-2-(cis-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide, or a salt thereof.

Abstract: The present disclosure relates to systems, apparatuses, and methods for assembling cartridges for aerosol delivery devices. A system may include assembly cells each including an assembly track and assembly carriages that ride thereon and which engage components of partially-assembled cartridges. A transfer apparatus may transfer partially-assembled cartridges between the assembly cells. In another example system, cartridges may be assembled on platforms on a rotary track. The platforms may include assembly grippers with sequentially-opening clamps configured to receive the components of the partially-assembled cartridges. Related methods are also provided.

Abstract: The disclosed systems and methods relate to allowing trading of over the counter (“OTC”) foreign exchange (“FX”) contracts on a centralized matching and clearing mechanism, such as that of the Chicago Mercantile Exchange's (“CME”'s) futures exchange system (the “Exchange”). The disclosed systems and methods allow for anonymous transactions, centralized clearing, efficient settlement and the provision of risk management/credit screening mechanisms to lower risk, reduce transaction costs and improve the liquidity in the FX market place. In particular, the disclosed embodiments increase speed of execution facilitating growing demand for algorithmic trading, increased price transparency, lower cost of trading, customer to customer trading, and automated asset allocations, recurring trades as well as clearing and settlement efficiencies.

Abstract: A timer circuit for use with a dual lane motor controller has two motor controllers, each motor controller generating PWM drive signals having a period defined by a respective timer of the timer circuit. The timer circuit comprises a first processing circuit associated with the first motor controller and comprising a first oscillator circuit, a first timer which outputs a first timer signal each time the oscillator circuit has completed a set integer number N of oscillations, and a second processing circuit associated with the second motor controller and comprising a second oscillator circuit.

Abstract: Apparatus, such as a respiratory therapy device 4000, may generate a signal representing an estimate of a patient breathing pattern when using a flow therapy device with an un-sealed patient interface. The device may include a blower and may generate a flow of air at a controlled flow rate. The apparatus may include a controller. The generation may involve computing an estimate of the breathing pattern as a function of a device flow rate signal; a device pressure signal; a device conductance; a patient conductance; and a coupling parameter that characterizes a degree of coupling between the interface and the patients nares. An estimate of an exit pressure representative of a pressure of a flow of air generated by the therapy device just outside an orifice of the unsealed interface may also be computed. An estimate of a flushing flow rate from the estimated exit pressure may also be computed.

Abstract: A p38 MAPK inhibitor for use in the treatment or prevention of severe influenza in a human patient. In some embodiments, the severe influenza maybe characterised by hypercytokinemia involving elevated levels of one or more pro-inflammatory cytokines. The p38 MAP kinase inhibitor may act to inhibit the release of such pro-inflammatory mediators from endothelial cells. In some embodiments, the p38 MAP kinase inhibitor may inhibit the release of IP 10 from endothelial cells, preferably in a dose-dependent manner.

Abstract: A system to remind people to take action to achieve their goals and form new habits by using the power of their focus and repetition. The system consists of a wearable device and a method. The wearable device is to send preselected interval vibrated reminders to connect to an action to achieve a specific goal. The method comprising of four steps, where a user in the first step chooses one goal to help the mind focus on it, then in the second step the user selects a time interval from the wearable device, then in the third step, the user mentally connect the vibrated reminder he receives from the wearable device to an action he must do to achieve the goal, then in the fourth step the user will use focus-repetition and meditation to put attention on in his goal to summon all the mind abilities to reach this goal.

Abstract: Disclosed herein are systems and methods for colocating virtual content. A method may include receiving first persistent coordinate data, second persistent coordinate data, and relational data. A third persistent coordinate data and a fourth persistent coordinate data may be determined based on input received via one or more sensors of a head-wearable device. It can be determined whether the first persistent coordinate data corresponds to the third persistent coordinate data. In accordance with a determination that the first persistent coordinate data corresponds to the third persistent coordinate data, it can be determined whether the second persistent coordinate data corresponds to the fourth persistent coordinate data. In accordance with a determination that the second persistent coordinate data corresponds to the fourth persistent coordinate data, a virtual object can be displayed using the relational data and the second persistent coordinate data via a display of the head-wearable device.

Abstract: A method and system are provided for streaming a video game from a server to a client. One example system includes the server configured to generate video frames for the video game responsive to input received from the client. An encoder that processes the video frames to generate compressed video frames and storing past encoder states in memory associated with the encoder. The server is configured to transmit the compressed video frames to the client. The server is configured to receive a feedback signal from the client to determine when one or more of the compressed video frames that were sent were not been received by the client. The encoder is configured to generate one or more next video frames as compressed video frames that are dependent on compressed video frames that are known to have been successfully received based on the feedback signal.

Abstract: This invention relates to methods and materials for providing a benefit to a plant by associating the plant with a complex endophyte comprising a host fungus further comprising a component bacterium, including benefits to a plant derived from a seed or other plant element treated with a complex endophyte. For example, this invention provides purified complex endophytes, purified complex endophyte components such as bacteria or fungi, synthetic combinations comprising said complex endophytes and/or components, and methods of making and using the same.

Abstract: The disclosed systems and methods relate to allowing trading of over the counter (“OTC”) foreign exchange (“FX”) contracts on a centralized matching and clearing mechanism, such as that of the Chicago Mercantile Exchange's (“CME”' s) futures exchange system (the “Exchange”). The disclosed systems and methods allow for anonymous transactions, centralized clearing, efficient settlement and the provision of risk management/credit screening mechanisms to lower risk, reduce transaction costs and improve the liquidity in the FX market place. In particular, the disclosed embodiments increase speed of execution facilitating growing demand for algorithmic trading, increased price transparency, lower cost of trading, customer to customer trading, and automated asset allocations, recurring trades as well as clearing and settlement efficiencies.

Abstract: Dual channel wireless communication system for monitoring and/or control of a machine (112), such as a press brake, by a remote interface device (10,12) that communicates data with a machine controller (18) over two channels CH1, CH2 in parallel. Also, a system and method to determine whether a remote interface device (10, 12) is within a range or zone of a machine (112) that the remote interface device wirelessly monitors and/or controls, uses an ultrasound transmitter-receiver arrangement (100, 102) and an electromagnetic (EM) transmitter-receiver arrangement (104, 106, 108, 110) to determine difference in ultrasound and EM time of flight and therefore whether or not the remote interface device is permitted to monitor and/or control the machine or is within range to monitor and/or control the machine.

Abstract: Systems and methods are disclosed to implement a self-learning machine assessment system that automatically tunes what data is collected from remote machines. In embodiments, agents are deployed on remote machines to collect machine characteristics data according to collection rule sets, and to report the collected data to the machine assessment system. The machine assessment system assesses the remote machines using the collected data, and automatically determines, based on what data was or was not needed during the assessment, whether an agent's collection rule set should be changed. Any determined changes are sent back to the agent, causing the agent to update its scope of collection. The auto-tuning process may continue over multiple iterations until the agent's collection scope is stabilized. In embodiments, the assessment process may be used to analyze the remote machine to determine security vulnerabilities, and recommend possible actions to take to mitigate the vulnerabilities.

Abstract: Embodiments are provided for replacing media items in a queue of a playback device. An example implementation involves receiving, at the playback device, first data indicating an addition of a first media item to a queue. The playback device determines that the first media item is no longer accessible to the playback device at a later second time. The playback device initiates a query for a media item similar to the first media item and receives second data indicating that a second media item has replaced the first media item in the queue, the second media item being similar to the first media item. In response, the playback device initiates playback of the second media item on the playback device.

Abstract: This disclosure pertains to the use of black liquors from kraft pulp mills as a source of catalysts for the thermochemical conversion of organic matter feedstocks to bio oils.

Abstract: An example implementation involves a playback device receiving a request to add continuous automated streaming audio content to a playback queue, the request indicating a playback start time, and the playback queue indicating a plurality of audio content. The implementation further involves the playback device adding the continuous automated streaming audio content to the playback queue. The example implementation also involves the playback device determining that a duration until the playback start time is less than a duration of the given audio content before playing a given audio content in the playback queue. The example implementation involves the playback device responsively, playing the continuous automated streaming audio content.