Abstract: Systems and methods for controlling thrust of an engine for an aircraft are described herein. A position of a thrust lever for controlling the engine is obtained from one or more sensors. Air data is obtained from one or more air data inputs. An air temperature data input is detected as compromised from the air data. In response to detecting the air temperature data input is compromised, a target engine rotational speed is determined based on the position of the thrust lever and at least one of altitude data and Mach number data from the air data. A rotational speed of the engine is adjusted to the target engine rotational speed to control thrust of the engine.

Abstract: Aspects of the invention described herein include a hydrogel prodrug and methods of making a hydrogel prodrug for drug delivery. Also contemplated are methods of treating, inhibiting, ameliorating or inhibiting a disease or disorder. Without being limiting, the methods for treatment can be directed to a cancer, HIV, a virus, pain, a bacterial infection, a neurological disorder, hemorrhaging, multiple sclerosis, diabetes, high blood pressure, Alzheimer's, or inhibiting a fungal growth in a subject in need.

Abstract: Aspects of the invention described herein include a hydrogel prodrug and methods of making a hydrogel prodrug for drug delivery. Also contemplated are methods of treating, inhibiting, ameliorating or inhibiting a disease or disorder. Without being limiting, the methods for treatment can be directed to a cancer, HIV, a virus, pain, a bacterial infection, a neurological disorder, hemorrhaging, multiple sclerosis, diabetes, high blood pressure, Alzheimer's, or inhibiting a fungal growth in a subject in need.

Abstract: Genetic constructs comprising reporter genes operably linked to cancer specific or cancer selective promoters (such as the progression elevated gene-3 (PEG-3) promoter and astrocyte elevated gene 1 (AEG-1) promoter) are provided, as are methods for their use in cancer imaging, cancer treatment, and combined imaging and treatment protocols, e.g. for imaging and/or treating spontaneous metastasis. Transgenic animals in which a reporter gene is linked to a cancer specific or cancer selective promoter, and which may be further genetically engineered, bred or selected to have a predisposition to develop cancer, are also provided.

Abstract: A tropism modified cancer terminator virus (Ad.5/3-CTV; Ad.5/3-CTV-M7) has been found to have infectivity that is Coxsackie Adenoviral Receptor (CAR) independent. The Ad.5/3-CTV (Ad.5/3-CTV-M7) may be used alone or in combination with other therapeutic agents such as agents that augment reactive oxygen (ROS) production, HDAC inhibitors, MCL-1 inhibitors and Bcl-2 inhibitors to treat a variety of cancers particularly including malignant glioma (GBM), renal cancer, prostate cancer, and colorectal cancer.

Abstract: The present invention relates to an injectable system combining a hydrogel, a bioceramic and a degradable matrix that provides for sustained drug delivery and structural support to recovering tissue, such as bone and the periodontium.

Abstract: A method and device for electroporating adipocytes in the adipose layer of tissue, where the device includes a frame, a first electrode coupled to the frame having a first contact surface, a second electrode coupled to the frame having a second contact surface, and where the first contact surf ace and the second contact surface define a treatment zone therebetween. The method including positioning a fold of tissue between the first and second electrodes such that the treatment zone formed between the two electrodes includes an adipose layer of tissue and no skeletal muscle.

Abstract: A tropism modified cancer terminator virus (Ad.5/3-CTV; Ad.5/3-CTV-M7) has been found to have infectivity that is Coxsackie Adenoviral Receptor (CAR) independent. The Ad.5/3-CTV (Ad.5/3-CTV-M7) may be used alone or in combination with other therapeutic agents such as agents that augment reactive oxygen (ROS) production, HDAC inhibitors, MCL-1 inhibitors and Bcl-2 inhibitors to treat a variety of cancers particularly including malignant glioma (GBM), renal cancer, prostate cancer, and colorectal cancer.

Abstract: Aspects of the invention described herein include a hydrogel prodrug and methods of making a hydrogel prodrug for drug deliver}?. Also contemplated are methods of treating, inhibiting, ameliorating or inhibiting a disease or disorder. Without being limiting, the methods for treatment can be directed to a cancer, HIV, a virus, pain, a bacterial infection, a neurological disorder, hemorrhaging, multiple sclerosis, diabetes, high blood pressure, Alzheimer's, or inhibiting a fungal growth in a subject in need.

Abstract: Aspects of the invention described herein include a hydrogel prodrug and methods of making a hydrogel prodrug for drug delivery. Also contemplated are methods of treating, inhibiting, ameliorating or inhibiting a disease or disorder. Without being limiting, the methods for treatment can be directed to a cancer, HIV, a virus, pain, a bacterial infection, a neurological disorder, hemorrhaging, multiple sclerosis, diabetes, high blood pressure, Alzheimer's, or inhibiting a fungal growth in a subject in need.

Abstract: Systems and methods for controlling thrust of an engine for an aircraft are described herein. A position of a thrust lever for controlling the engine is obtained from one or more sensors. Air data is obtained from one or more air data inputs. An air temperature data input is detected as compromised from the air data. In response to detecting the air temperature data input is compromised, a target engine rotational speed is determined based on the position of the thrust lever and at least one of altitude data and Mach number data from the air data. A rotational speed of the engine is adjusted to the target engine rotational speed to control thrust of the engine.

Abstract: A tropism modified cancer terminator virus (Ad.5/3-CTV; Ad.5/3-CTV-M7) has been found to have infectivity that is Coxsackie Adenoviral Receptor (CAR) independent. The Ad.5/3-CTV (Ad.5/3-CTV-M7) may be used alone or in combination with other therapeutic agents such as agents that augment reactive oxygen (ROS) production, HDAC inhibitors, MCL-1 inhibitors and Bcl-2 inhibitors to treat a variety of cancers particularly including malignant glioma (GBM), renal cancer, prostate cancer, and colorectal cancer.

Abstract: Aspects of the invention described herein include a hydrogel prodrug and methods of making a hydrogel prodrug for drug deliver}?. Also contemplated are methods of treating, inhibiting, ameliorating or inhibiting a disease or disorder. Without being limiting, the methods for treatment can be directed to a cancer, HIV, a virus, pain, a bacterial infection, a neurological disorder, hemorrhaging, multiple sclerosis, diabetes, high blood pressure, Alzheimer's, or inhibiting a fungal growth in a subject in need.

Abstract: Aspects of the invention described herein include a hydrogel prodrug and methods of making a hydrogel prodrug for drug delivery. Also contemplated are methods of treating, inhibiting, ameliorating or inhibiting a disease or disorder. Without being limiting, the methods for treatment can be directed to a cancer, HIV, a virus, pain, a bacterial infection, a neurological disorder, hemorrhaging, multiple sclerosis, diabetes, high blood pressure, Alzheimer's, or inhibiting a fungal growth in a subject in need.

Abstract: A remote art jurying system in which art jurors independently evaluate works of art at different locations, times and places. A central database presents information about each work of art and/or the artist to an individual juror. The database provides images of the artwork along with relevant information. Each juror can access the database independent of other jurors in terms of location, or time. The system provides enhanced voting methods. The juror can review or change their votes at any time prior to final submission. They can review all works of art, by categories of art, or by scores. The juror reviews artwork thumbnail images, which can be used to select high resolution images with extended information. Selected categories of art can be enhanced by eliminating the lowest scores to balance artwork finalists across multiple categories of art.

Abstract: A tropism modified cancer terminator virus (Ad.5/3-CTV; Ad.5/3-CTV-M7) has been found to have infectivity that is Coxsackie Adenoviral Receptor (CAR) independent. The Ad.5/3-CTV (Ad.5/3-CTV-M7) may be used alone or in combination with other therapeutic agents such as agents that augment reactive oxygen (ROS) production, HDAC inhibitors, MCL-1 inhibitors and Bcl-2 inhibitors to treat a variety of cancers particularly including malignant glioma (GBM), renal cancer, prostate cancer, and colorectal cancer.

Abstract: A diagnostic system and method for an electric power steering system are provided. The diagnostic system includes a first microprocessor that determines a first relative position value indicating the relative rotational position of the rotatable shaft at the first time based on the signals from first and second position sensors. A second microprocessor determines a second relative position value indicating the relative rotational position of the rotatable shaft at the first time based on the signals from third and fourth position sensors. The first microprocessor determines whether the first relative position value is an acceptable value based on a difference between the first relative position value and the second relative position value.

Abstract: A remote art jurying system in which art jurors independently evaluate works of art at different locations, times and places. A central database presents information about each work of art and/or the artist to an individual juror. The database provides images of the artwork along with relevant information. Each juror can access the database independent of other jurors in terms of location, or time. The system provides enhanced voting methods. The juror can review or change their votes at any time prior to final submission. They can review all works of art, by categories of art, or by scores. The juror reviews artwork thumbnail images, which can be used to select high resolution images with extended information. Selected categories of art can be enhanced by eliminating the lowest scores to balance artwork finalists across multiple categories of art.

Abstract: A system and a method for determining an absolute position of a motor shaft in an electric power steering system during an ignition off state are provided. The system includes a microprocessor that energizes first and second position sensors to generate first and second signals, respectively, at a first time, and third and fourth signals, respectively, at a second time. The microprocessor determines a first relative position value based on the first and second signals, and a second relative position value based on the third and fourth signals. The microprocessor determines an amount of relative rotation of the shaft during the ignition off state based on the first and second relative position values, and determines a current absolute position value based on a previously stored absolute position value and the amount of relative rotation of the rotatable shaft.

Abstract: Genetic constructs comprising reporter genes operably linked to cancer specific or cancer selective promoters (such as the progression elevated gene-3 (PEG-3) promoter and astrocyte elevated gene 1 (AEG-1) promoter) are provided, as are methods for their use in cancer imaging, cancer treatment, and combined imaging and treatment protocols, e.g. for imaging and/or treating spontaneous metastasis. Transgenic animals in which a reporter gene is linked to a cancer specific or cancer selective promoter, and which may be further genetically engineered, bred or selected to have a predisposition to develop cancer, are also provided.