Abstract: According to one aspect, a tissue fastening device may include a first body including a proximal end, a distal end, and defining a longitudinal axis; and a fastening device coupled to the distal end of the first body. The fastening device may include a longitudinal body comprising a cartridge; the cartridge configured to hold one or more fasteners; an anvil rotatable relative to the cartridge of the longitudinal body; a fastener actuator configured to move relative to the cartridge to deploy the one or more fasteners from the cartridge; and an actuation wire coupled to the fastener actuator, extending through the first body, and positioned at least partially exterior to the longitudinal body, the cartridge, or the anvil.

Abstract: The present disclosure is directed to a medical instrument. The medical instrument may include a delivery device and a retraction mechanism including a target tissue anchor and a first stabilizing anchor, wherein the target tissue anchor attaches to target tissue and connects to the delivery device.

Abstract: A multi-stringed musical instrument, such as a guitar, having a neck with a partially hollow interior containing a number of linear actuators, each connected to a fret which projects proud of the neck and is in contact with a taught string, wherein the linear actuators are controlled by means of a user-selected input signal via functional communication with a small control panel, tablet, smartphone, computer or laptop.

Abstract: The described technology is generally directed towards session mapping in multi-access communication networks. A main session can be established between a mobile edge computing device (MEC) and a core network. The MEC can also establish multiple respective virtual sessions with multiple respective access network computing devices, and the MEC can map the main session to the multiple respective virtual sessions. A user equipment (UE) can connect to any of the respective access network computing devices, thereby communicating via any of the respective virtual sessions.

Abstract: A multi-spool turbomachine having an electric machine that can be controlled to input power to one of the spools of the turbomachine is provided. In one aspect, the multi-spool turbomachine can be a hybrid electric gas turbine engine for an aircraft. The hybrid electric gas turbine engine can include a first spool, a second spool, and an electric machine operatively coupled with the first spool. In response to an increase in thrust demand, the electric motor receives electrical power from an electrical power source. In turn, the electric machine applies a torque to the first spool, causing the first spool to increase in rotational speed. In this manner, the electric machine can electrically assist the turbomachine to meet the increase in thrust demand.

Abstract: Facilitating mobility as a service in advanced networks (e.g., 5G, 6G, and beyond) is provided herein. Operations of a method can comprise evaluating, by a system comprising a processor, a group of characteristics of a device. The method also can comprise enabling, by the system, a mobility management function as a mobility microservice. Further, the method can comprise activating, by the system, microservices of a group of microservices, comprising the mobility microservice, based on the group of characteristics of the device.

Abstract: The present disclosure relates to the field of tissue dissection. Specifically, the present disclosure relates to medical devices which lift and retract tissue during a dissection procedure to improve visualization of the target tissue and mitigate obstruction of dissection tools. In particular, the present disclosure relates to a tissue retraction device which moves from a constrained to relaxed configuration to immobilize and retract the dissected portion of target tissue during a dissection procedure.

Abstract: A device includes a capsule extending longitudinally from a proximal end to a distal end and including a channel extending therethrough. The capsule is releasably coupled to a proximal portion of the device. Device also includes a first arm rigidly fixed to the distal end of the capsule to extend distally therefrom. In addition, Device includes a second arm, a proximal end of which is slidably received within the capsule so that the second arm is movable between an open configuration, in which the second arm is moved laterally away from the first arm and a distal end of the second arm is moved distally past the distal end of the first arm, and a closed configuration, in which the second arm is moved toward the first arm and the distal end of the second arm is moved proximally toward the distal end of the first arm.

Abstract: Automatic neighbor relationships (ANR) can be implemented within a radio access network intelligent controller (RIC), which receives load information from network nodes and user equipment measurements from user equipment. The RIC can create and maintain real-time load information and leverage slicing knowledge of neighbor cells during mobility to direct the user equipment to various network slices. Thus, an enhanced radio access network (RAN) neighbor relationship that utilizes slicing information can provide slice level RAN neighbor visibility on top of physical ANR relationships to enable enhancements for mobility management optimization.

Abstract: A system for metal detection comprises a single aperture comprising two or more sets of detection coils that surround the perimeter of the aperture. A flow path of materials passes through the aperture. Each set of detection coils comprises a transmitter and two receiver coils, with the transmitter coil located between the two receiver coils. Each set of detection coils is at a different angle relative to the flow path.

Abstract: A process utilizes electron beam generated ionizing radiation or low energy electron irradiation to effect cure of polymerizable stain compositions applied to wood planking. The electron beam ionization process generates sufficient energy to break bonds and generate new cross-links within the polymeric stain composition thus bonding the stain strongly within the pores and surface of the wood planks further creating a durable treatment. The electron beam ionization process simplifies the curing process by eliminating or reducing the need for expensive photoinitiators. Pre-stained wood planking is suitable for exterior decking materials and building panels requiring a combination of color affected and durable finishes, thereby eliminating the need for field installation of pretreatments, stains, coatings and the like. These electron beam cured wood planks take on an assortment of appearances including clear, natural, translucent, and solid hues.

Abstract: The present application provides methods of treating hidradenitis suppurativa in a patient in need thereof, comprising administering to the patient a therapeutically effective amount of a compound which inhibits JAK1 and/or JAK2, or a pharmaceutically acceptable salt thereof.

Abstract: An anthraquinone compound of formula I (such as the compounds of formulae II to X) and processes for making the same are provided. Pharmaceutical compositions for use in the treatment of cancer, optionally in combination with an agent capable of reducing the level of oxygenation of a tumour, are also provided. Additionally, an option for combination with chemotherapeutic and radiotherapeutic modalities to enhance overall tumour cell kill is provided. Methods for the detection of cellular hypoxia, both in vivo and in vitro, are additionally provided.

Abstract: A method of facilitating a match between an employer with at least one job opening and job seekers is provided. The employer has a set of position preferences related to the job opening. The job seekers have suitability data, resumes, etc., that are provided to the employer. The suitability data includes normalized assessment data. The method includes the steps of: determining a position quotient based on the position preferences; deriving a performance quotient for each job seeker; comparing each the performance quotient to the position quotient; and ranking each the job seeker based on the comparison of the performance quotient to the position quotient.

Abstract: The present application provides combination therapies comprising a JAK inhibitor and a ROCK inhibitor, and methods of using the same to treat disorders such as graft versus host disease (GVHD), restrictive allograft syndrome (RAS), chronic lung allograft dysfunction (CLAD), and systemic sclerosis (scleroderma).

Abstract: A microporous substrate for detection of surface bound target analyte molecules includes a microporous substrate material having opposed surfaces and tapered micropores extending through the substrate with the micropores having wider openings on one side of the substrate compared to the other side. The micropores have bound therein analyte specific receptors complementary to the target molecules. When a liquid sample containing the target analyte molecules with optical probes attached to the target molecules is flowed through the substrate, they bind to their complementary analyte specific receptors and emit light. This substrate structure gives an increase in the collection efficiency of light emitted from optical probes when the light is detected by a light detector spaced from the side of the substrate facing the larger micropores openings compared to a light collection efficiency of light emitted from the optical probes when the micropores are straight and not tapered.

Abstract: A turbine engine includes a compressor section, a combustion section, a turbine section, and an exhaust section in serial flow order and together defining a core air flowpath; a fuel delivery system for providing a flow of fuel to the combustion section; and a waste heat recovery system. The waste heat recovery system includes a heat source exchanger in thermal communication with the turbine section, the exhaust section, or both; a heat sink exchanger in thermal communication with the fuel delivery system, the core air flowpath, or both; a thermal transfer bus including a thermal transfer fluid and extending from the heat source exchanger to the heat sink exchanger; and a pump in fluid communication with the thermal transfer bus downstream of the heat source exchanger and upstream of the heat sink exchanger for increasing a temperature and a pressure of the thermal transfer fluid in the thermal transfer bus.