Abstract: Devices and methods for the treatment of heart conditions, and other medical purposes, include cardiac pacing systems. For example, this document describes temporary transvenous endocardial pacemaker systems and devices for deploying such systems without the need for conventional imaging procedures.

Abstract: A portable, single-fixation, magnetic derailment mitigation device may be fixed on a rail track for measuring the deflection of the rail track. The magnetically fixing device is used for measuring vertical track deflection (sleeper voids), horizontal track deflection, ambient and rail temperature, rail angle, vibration, displacement, and location. The derailment mitigation device sends digital notifications and/or alarms during the live train and/or freight operations to help prevent derailments, rail buckles, breaks, and pull apart. The measured data and/or all events obtained from the derailment mitigation device is stored in the data storage such as cloud storage and viewed from any smart devices.

Abstract: An endoscopic system for sensing one or more characteristics at an environment of a worksite comprises a shaft comprising a proximal end portion and a distal end portion; an electrically active sensor system comprising a sensor positioned to sense at least one characteristic of an environment in which the distal end portion of the shaft is located; an electrical power transmission line electrically coupled to the sensor and extending along the shaft, the electrical power transmission line configured to transmit power to the sensor; and a floating ground element electrically isolated from an earth ground and operably coupled to the electrically active sensor system. An overall capacitance between the electrical power transmission line and the floating ground element is greater than an overall capacitance between the floating ground element and earth ground.

Abstract: Systems, devices and methods are provided for inserting at least a portion of an in vivo analyte sensor for sensing an analyte level in a bodily fluid of a subject. In particular, disclosed herein are various embodiments of sensor control devices, and components thereof, designed to reduce the size and the number of internal components of the sensor control device. Further, the embodiments of the sensor control device and related sensor features disclosed herein are designed to increase comfort and convenience for the subject.

Abstract: This disclosure provides an enhanced operating table and room, an insulated conductor, and a filtration system. The table includes an attachment, controlling parameters during surgery, a control, and a console. The attachment is moveable relative to at least one reference point. The console allows monitoring parameters during surgery. The room includes sensors integrated throughout and a data module in communication with the sensors. The data module receives data from the plurality of sensors, stores the received data in memory, and analyzes and processes the stored data. The insulated conductor includes an electrical conductor and an insulator. The insulator partially electrically or thermally insulates the electrical conductor. The filtration system removes particles within a fluid A transducer generates a pressure gradient to promote the particles to flow. Alternatively, the filtration system can include a robotic system. The robotic system charges particles such that the particles within the fluid adhere.

Abstract: The present disclosure generally relates to a rail warning system using wireless portable transmitters/receivers. The rail warning system uses a chirp spread spectrum modulation scheme, and alerts personnel in work zones on or near train tracks as well as optionally, on track equipment and train operators, of approaching trains or on track equipment. Portable wayside devices may also be positioned on the rail web, optionally magnetically, to alert work personnel, allowing for secure placement but also portability to other locations on the same track or adjacent tracks.

Abstract: The present invention provides a method for stabilizing a fractured bone. The method includes positioning an elongate rod in the medullary canal of the fractured bone and forming a passageway through the cortex of the bone. The passageway extends from the exterior surface of the bone to the medullary canal of the bone. The method also includes creating a bonding region on the elongate rod. The bonding region is generally aligned with the passageway of the cortex. Furthermore, the method includes positioning a fastener in the passageway of the cortex and on the bonding region of the elongate rod and thermally bonding the fastener to the bonding region of the elongate rod while the fastener is positioned in the passageway of the cortex.

Abstract: An aspect of the disclosure provides a decoupling wearable article for body piercings including a post, a front portion, and a back portion. The post has opposite longitudinal ends and extends longitudinally through a body piercing. The front and back portions releasably couple to opposite longitudinal ends of the post such that at least one of the front and back portions decouples from the post when a predetermined force is applied. An aspect of the disclosure provides a removable protector for a wearable article including a first protector portion configured to be removably coupled to and externally covers at least portion of the wearable article. Another aspect of the disclosure provides a conformable earpiece for acoustic transmission including an earpiece received an ear canal with conformable section of the earpiece conforming to the ear canal. The conformable earpiece including a speaker received within the conformable section of the earpiece.

Abstract: Surgical systems and methods to facilitate surgical navigation involve a scanner to produce a scan of a vessel on a bone and a camera configured to detect markers coupled to the bone. Controller(s) track the bone based on detection of the markers by the camera and determine, based on the scan, one or more characteristics of the vessel on the bone. The controller(s) obtain imaging data of the bone and register the imaging data and the one or more characteristics of the vessel to the bone.

Abstract: The present disclosure provides a system for injecting a drug eluting construct in a patient. The construct includes multiple cellular based microcaspules, wherein the multiple cellular based microcapsules create at least one of a plurality of layers or sections of microcapsules joined together to comprise an implant. There is a medicinal agent within the microcapsules. A syringe and needle inject the implant constructed of microcapsules into the patient at least one of during and after a surgical procedure. The medicinal agent controllably releases into the patient both immediately and at a delayed time.

Abstract: The invention relates generally to expression vectors and pharmaceutical compositions comprising a first, second, and/or third modified tRNA and the use of expression vectors and pharmaceutical compositions to express in a mammalian cell a functional gene product encoded by a gene containing a premature termination codon and/or to treat a disorder mediated by a premature termination codon, e.g., Dravet syndrome.

Abstract: Provided herein are conformation-specific antibodies which bind to protein aggregates, such as amyloid fibrils, including aggregates of glucagon and liraglutide. Also provided are methods of using the antibodies to detect protein aggregates in samples, and methods for identifying aggregate-binding antibodies.

Abstract: A linear transfer system for a collaborative robot includes a linear bearing extending along a linear axis. A carriage on the linear bearing moves along the linear axis and supports a collaborative robot. One or more load cells are supported on either axial end of the carriage. A motor causes movement of the carriage along the linear axis under the control of a motor control circuit. The circuit receives input signals indicative of forces applied to the load cells. During a programming mode for the system, the circuit may generate control signals for the motor causing movement of the carriage along the linear axis corresponding to the forces applied to the load cells. During an operating mode of the system, the circuit may detect collisions by comparing the forces to a threshold and generating control signals to halt movement of the carriage if a predetermined condition is met.

Abstract: A method and apparatus for processing documents are provided. The apparatus includes a feeder for receiving a packet of a plurality of documents and separating the documents to serially feed the documents to a scanner. A drop feeder conveys the document packets to the feeder. A sensor provides information related to the thickness of the document packets and the drop feeder is controlled in response to the information related to the thickness of a packet in the feeder. The method includes the control of the drop feeder in response to information related to the thickness of a document packet at the feeder.

Abstract: A tissue fixation system is provided for dynamic and rigid fixation of tissue. A fastener connected with an elongate fastening member, such as a cable, wire, suture, rod, or tube, is moved through a passage between opposite sides of tissue. A medical device is used to secure the fastener to the elongate fastening member. The medical device includes a tensioning mechanism for tensioning the elongate fastening member. As crimping mechanism is used to secure the fastener to the elongated member, where a cutting mechanism cut the excess portion of the elongated member.

Abstract: An ankle stretch orthosis includes a foot assembly having a ball support assembly adjustably mounted on a foot plate. The foot assembly includes an adjustment mechanism for selectively adjusting a position of ball support assembly relative to the foot plate to align the ball support assembly with a ball portion of a foot that is one of supinated and pronated.

Abstract: A portable, single-fixation, magnetic derailment mitigation device may be fixed on a rail track for measuring the deflection of the rail track. The magnetically fixing device is used for measuring vertical track deflection (sleeper voids), horizontal track deflection, ambient and rail temperature, rail angle, vibration, displacement, and location. The derailment mitigation device sends digital notifications and/or alarms during the live train and/or freight operations to help prevent derailments, rail buckles, breaks, and pull apart. The measured data and/or all events obtained from the derailment mitigation device is stored in the data storage such as cloud storage and viewed from any smart devices.

Abstract: An assembly for delivering an analyte sensor comprising a sensor control device. The sensor control device comprises an electronics housing with a shell having a first aperture and a first interface, and a mount having a second aperture and second interface, wherein the housing has an interior space. The two interfaces define a first sterile barrier. The housing also comprises a first mating member, a circuit board, and an analyte sensor. The assembly also comprises an applicator to deliver the sensor, and comprising a housing and a cap removably coupled to the housing to seal the applicator's interior, a sharp hub, and a second mating member extending within the first or second aperture, which mates with the first mating member to define a second sterile barrier. The sensor control device also comprises a collimator, a third sterile barrier, and a fourth sterile barrier which define a sterilization zone.

Abstract: An adapter couples an ultraviolet (UV) disinfecting device to a container suitable for holding liquid. The adapter may be a lid adapter that also functions as a lid for the container. The adapter includes a body and a coupler. The body couples to the UV disinfecting device, and the coupler couples to the container. In this way, the UV disinfecting device is in communication with the interior of the container.

Abstract: A method for printing a 3D part includes decreasing a temperature of a build material in a nozzle of a 3D printer below a melting point of the build material, which causes the build material in the nozzle to transition from a liquid state to a solid state. The method also includes increasing the temperature of the build material in the nozzle above the melting point of the build material, which causes the build material in the nozzle to transition from the solid state to a sludgy state. An occlusion and the build material in the sludgy state are ejected from the nozzle.