Abstract: The present disclosure is directed to a power tool including a motor housing and an electric motor situated within the motor housing. The electric motor is configured to provide rotational energy to rotate an output device of the power tool about an output axis. The power tool also includes a cover configured to cover at least a portion of a surface of the motor housing that faces the output device. The power tool further includes a first lighting device located within the cover and a second lighting device located within the cover. The first lighting device and the second lighting device are located around the output axis and are separated from each other by at least 130 degrees about the output axis. The power tool also includes first power wires configured to provide power to the first lighting device from a power source of the power tool.

Abstract: Provided herein are antibodies and methods of use thereof. The antibodies as disclosed herein bind to CD163+ on cells, such as on macrophages. These antibodies can be used in methods of treatment, such as methods of treating cancer.

Abstract: A portable electroplating system with components integrated into a complete system, rather than separated and disjointed. A single electroplating system can be self-contained to include all necessary rectifiers, tanks, cleaning functionalities, and other helpful or necessary items. By using smaller components than conventional electroplating systems, the system can allow for more economical use of chemicals, solutions, and energy and can be utilized more efficiently towards a unique shape or size of object to be plated. The system can also include wheels to make the system portable. A rack management system can be employed to move objects from one location to another within the system.

Abstract: A hypodermic interface assembly is disclosed. The hypodermic interface assembly includes a hub, a cannula, and a cannula carrier. The cannula carrier is non-removably-connected to the cannula. The cannula carrier is controllably separable from the hub.

Abstract: A leadless cardiac pacemaker is provided which can include any number of features. In one embodiment, the pacemaker can include a tip electrode, pacing electronics disposed on a p-type substrate in an electronics housing, the pacing electronics being electrically connected to the tip electrode, an energy source disposed in a cell housing, the energy source comprising a negative terminal electrically connected to the cell housing and a positive terminal electrically connected to the pacing electronics, wherein the pacing electronics are configured to drive the tip electrode negative with respect to the cell housing during a stimulation pulse. The pacemaker advantageously allows p-type pacing electronics to drive a tip electrode negative with respect to the can electrode when the can electrode is directly connected to a negative terminal of the cell. Methods of use are also provided.

Abstract: A structural connector system for providing an electrical connection between electronic componentry is disclosed. The structural connector system includes a structural member, including an electrically insulating matrix, an electrically conducting path, a first end surface, a second end surface, and a first component engaging surface. The first component engaging surface includes a first mechanical coupler configured to mechanically couple a first electronic component or a first chassis component to the structural member and a first electrical coupler configured to electrically couple the first electronic component or the first chassis component to a first end of the electrically conducting path.

Abstract: Provided is a wall grommet, which can be installed through the surfaces of walls to route wiring in the walls' interior spaces. In particular, the wall grommet is configured for running power cords inside walls and presenting the electrical connectors of a power cord in a manner such that power cords are hidden from view. The grommet may comprise a housing, which defines an interior space that is adapted to hold either the female connector or male connector of a power cord. The housing may be configured to enclose and secure the electrical connector of the power cord in the housing.

Abstract: The present invention relates to efficient synthetic processes useful in the preparation of antiviral nucleosides, particularly uridine 4-oxime 5?-(2-methylpropanoate) {(2R,3S,4R,5R)-3,4-dihydroxy-5-[4-(hydroxyimino)-2-oxo-3,4-dihydropyrimidin-1(2H)-yl]oxolan-2-yl}methyl 2-methylpropanoate and pharmaceutically acceptable salts, derivatives, tautomers, isomers, and prodrugs of, which may be active as antiviral agents, as well as compositions and methods thereof. The present invention also encompasses intermediates useful in the disclosed synthetic processes and the methods of their preparation.

Abstract: A continuous (multi-)analyte sensor device is provided, comprising a (multi-)analyte sensor operably coupled to a signal transducer, the (multi-)analyte sensor comprising at least one membrane, the least one membrane comprising a least one first transducing element, and at least one of a mediator and/or a regenerative cofactor.

Abstract: Provided herein are drug delivery devices, comprising a scaffold comprising one or more biocompatible materials, one or more chambers containing a plurality of cells, one or more membranes, and one or more nutrient supplementation systems. Also provided are methods of treating or preventing diseases and disorders in a subject in need thereof, comprising administering to the subject the drug delivery devices disclosed herein, and methods of making the drug delivery devices disclosed herein.

Abstract: Acrylic pressure-sensitive adhesive (“PSA”) compositions crosslinked with a small-molecule crosslinker containing a single, thermally reversible moiety represented by the structure (I) (Formula I)). wherein each R1 is independently —H or —CH3, each X is independently C2-C6 alkyl, and each R2 is independently a C1-C6 alkyl group or an aromatic group. Under high temperature conditions the crosslinks may be broken, thus allowing for good coating and dispensing of the PSA. Upon cooling, the crosslinks reform to create a gelled PSA network without need of additional post-processing curing steps.

Abstract: A method of treating a disease or pathology caused by an increase in levels of inflammatory cytokines comprising providing the subject with a compound of Formula I, (I) wherein, R1 is a C1-C20 branched or unbranched hydrocarbon; R3 is (II); or R4 is H or a pharmaceutically acceptable cation; R5 is a C1-C10 branched or unbranched hydrocarbon or optionally substituted with one or more groups; R6 is a C1-C10 branched or unbranched hydrocarbon or optionally substituted; R7 is a C0-C20 branched or unbranched hydrocarbon; R8 is H or a C0-C20 branched or unbranched hydrocarbon; X is a direct linkage, CH2, O or NH; Y is a direct linkage, CH2, O or NH; and, each stereogenic center is independently R, S or racemic.

Abstract: A computer system displays a first view of a user interface of a first application with a first size at a first position corresponding to a location of at least a portion of a palm that is currently facing a viewpoint corresponding to a view of a three-dimensional environment provided via a display generation component. While displaying the first view, the computer system detects a first input that corresponds to a request to transfer display of the first application from the palm to a first surface that is within a first proximity of the viewpoint. In response to detecting the first input, the computer system displays a second view of the user interface of the first application with a second size and an orientation that corresponds to the first surface at a second position defined by the first surface.

Abstract: A panel of a structure includes an outer layer and an inner layer that is positioned closer to an interior surface of the structure than the outer layer. An intermediate layer is positioned between the outer layer and the inner layer, and a mask layer is positioned between the outer layer and the intermediate layer. The mask layer includes an outer portion and an inner portion, where the outer portion is positioned between the outer layer and the intermediate layer, and the inner portion is positioned between the outer portion and the intermediate layer. The outer portion and the inner portion include different visual attributes.

Abstract: The present invention relates to methods, devices and systems for associating consumable data with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system adjusts one or more steps of an assay protocol based on consumable data specific for that consumable. Various types of consumable data are described, as well as methods of using such data in the conduct of an assay by an assay system. The present invention also relates to consumables (e.g., kits and reagent containers), software, data deployable bundles, computer-readable media, loading carts, instruments, systems, and methods, for performing automated biological assays.

Abstract: Provided are neutral Pt or Pd organometallic compounds comprising a tetradentate ligand, wherein the organometallic compound comprises at least one Pt—C or Pd—C bond. Also provided are formulations comprising these organometallic compounds. Further provided are organic light emitting devices (OLEDs) as well as related consumer products that utilize these organometallic compounds.

Abstract: Disclosed are embodiments directed to security methods applied to connections between components in a distributed (networked) system including medical and non-medical devices, providing secure authentication, authorization, patient and device data transfer, and patient data association and privacy for components of the system.

Abstract: A seeding system includes a commodity tank configured to store a commodity, the commodity tank having an outlet. A meter has a meter inlet at the outlet of the commodity tank, a meter outlet, and a metering device between the meter inlet and the meter outlet. A manifold has a commodity inlet at the meter outlet, a first shoot having a first air inlet and a first manifold outlet, and a second shoot having a second air inlet and a second manifold outlet. A valve is positioned upstream of the first and second air inlets and configured to selectively direct an airflow to the first air inlet and to selectively direct the airflow to the second air inlet. Each of the first shoot and the second shoot are in selective communication with the commodity inlet to receive the commodity therefrom.

Abstract: Disclosed are systems and methods for generating graphical displays of analyte data and/or health information. In some implementations, the graphical displays are generating based on a self-referential dataset that are modifiable based on identified portions of the data. The modified graphical displays can indicate features in the analyte data of a host.

Abstract: Wax-based compositions for making barrier layers used in oral treatment devices are thermally stable when formed into a flat sheet or three-dimensional article to a temperature of at least 45° C. and are plastically deformable at room temperature (25° C.). The wax-based compositions include a wax fraction homogeneously blended with a polymer fraction. The wax fraction includes at least one wax and the polymer fraction includes at least one polymer selected such that, when the at least one wax and at least one polymer are homogeneously blended together, they yield a wax-based composition having the desired properties of thermal stability and plastic deformability. Barrier layers and oral treatment devices made from such wax-based compositions are dimensionally stable to a temperature of at least 40° C. without external support and can be plastically deformed in a user's mouth to become at least partially customized to the size and shape of user's unique dentition.