Abstract: A tripod includes: a hub defining a set of leg mounts; a set of legs configured to telescopically extend from the hub and couple to the set of leg mounts; a center column including a spherical end; and a head pivotably coupled to the spherical end. The head further includes: a base section; a camera platform arranged over the base section; a set of flanges extending below the base section and extending around the spherical end; a hat arranged over the spherical end; a pivot control ring arranged about the base section, configured to drive the hat into the spherical end to fix the head on the spherical end responsive to rotation in a first direction about the base section, and configured to retract the hat from the spherical end to unlock the head from the spherical end responsive to rotation in a second direction about the base section.

Abstract: Disclosed are systems and methods that automatically classify, segment, and parse content data using artificial intelligence and natural language processing technology, and generate graphical user interfaces that allow end users to dynamically filter content data for display. The systems processes volumes of content data to identify interrogative data, content sources that generated the interrogative data, and subject identifiers relating to the content data. The system generates graphical user interfaces that allow end users to effectively filter the data by choosing between layouts that display one or more of the various categories of data, including the interrogative data, content source identifiers, and/or subject identifiers.

Abstract: The present disclosure relates generally to compounds that bind to and act as degraders of an IKAROS Family Zinc Finger (IKZF) protein, such as IKZF2 (Helios) and/or IKZF4 (Eos). The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding and degradation of an IKZF protein, such as IKZF2 and/or IKZF4, including cancer.

Abstract: A system for managing advertisements in an in-flight entertainment (“IFE”) system operating on an airplane can include an inventory processing device and a non-transitory computer readable medium. The non-transitory computer readable medium can be communicatively coupled to the inventory processing device to cause the inventory processing device to perform operations. The operations can include determining an inventory of targeted advertisements for future flights. The operations can further include receiving a request to use a portion of the inventory for advertisements associated with an advertiser. The operations can further include transmitting instructions to an IFE controller on-board the airplane to cause the IFE controller to provide the advertisements during targeted advertisement opportunities during a flight.

Abstract: A retrofit mining haul truck includes a hybrid hydrogen fuel cell/battery-based powerplant in place of a carbon fuel-based powerplant. The retrofit mining haul truck includes a frame, a tray coupled to the frame, and a deck coupled to the frame forward of at least a portion of the tray. A battery system is mounted to the deck of the retrofit mining haul truck. A hydrogen storage system (HSS) is installed in an engine bay volume of the retrofit mining haul truck. The engine bay was configured to contain a combustion engine (e.g., a diesel engine) prior to retrofitting the retrofit mining haul truck. At least a portion of a fuel cell system is installed in a wheel pocket of the retrofit mining haul truck. The wheel pocket was configured to contain a diesel tank prior to retrofitting the retrofit mining haul truck.

Abstract: Disclosed are systems and methods for generating graphical displays of analyte data and/or health information. In some implementations, the graphical displays are generating based on a self-referential dataset that are modifiable based on identified portions of the data. The modified graphical displays can indicate features in the analyte data of a host.

Abstract: A sensor pod system includes one or more sensor pods with a plurality of sensors configured to collect data from an environment. A sensor pod may have an effective field of view created by individual sensors with overlapping fields of view. The sensor pod system may include sensors of different types and modalities. Sensor pods of the sensor pod system may be modularly installed on a vehicle, for example, an autonomous vehicle and collect and provide data of the environment during operation of the vehicle.

Abstract: A humidification system can include a heater base, a humidification chamber, and a breathing circuit. A cartridge can be removably coupled to the heater base. The cartridge can include various sensors, probes, sensor wire connectors, heater wire connectors, and/or other features. The cartridge can include features configured to mate with corresponding features on the humidification chamber and the heater base. The cartridge includes a memory, such as an EEPROM, or other suitable storage device. When the cartridge is installed on the heater base, the memory is electrically connected to a processor and/or memory of the heater base. Various models of cartridges can be produced for use with different humidification chambers, breathing circuits, and/or therapies. A connector can be configured to couple an inspiratory conduit to an outlet port of the humidification chamber. The connector can provide a pneumatic connection to the outlet port and an electrical connection to the cartridge.

Abstract: A uniform enclave interface is provided for creating and operating enclaves across multiple different types of backends and system configurations. For instance, an enclave manager may be created in an untrusted environment of a host computing device. The enclave manager may include instructions for creating one or more enclaves. An enclave may be generated in memory of the host computing device using the enclave manager. One or more enclave clients of the enclave may be generated by the enclave manager such that the enclave clients configured to provide one or more entry points into the enclave. One or more trusted application instances may be created in the enclave.

Abstract: Provided is an apparatus (100) for transporting sweat droplets (112) to a sensor. The apparatus comprises a chamber (102) for filling with sweat. The chamber has an inlet (104) lying adjacent the surface of the skin (106), which inlet permits sweat to enter and fill the chamber. The chamber has an outlet (114) from which a sweat droplet protrudes once the chamber has been filled. The apparatus further comprises a fluid transport assembly which is designed to enable the sweat droplet protruding from the outlet to become detached from the outlet of the chamber. The sweat droplet is subsequently transported by the fluid transport assembly to the sensor. Once the protruding droplet has been released from the outlet, the outlet is made available for a subsequent sweat droplet to protrude therefrom upon further filling of the chamber.

Abstract: The present invention relates to compounds of formula (I) that function as inhibitors of METTL3 (N6-adenosine-methyltransferase 70 kDa subunit) enzyme activity: W—X—Y—Z (I) wherein X, Y and Z are each as defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, and autoimmune diseases, as well as other diseases or conditions in which METTL3 activity is implicated.

Abstract: An input regarding security characteristics of a project is received. For example, a security characteristic of a project may be insecure storage of data related to confidentiality. The project is scanned for one or more security requirements based on the received security characteristics. A list of security requirements is built for the project based on the received first input. A machine learning process is used to identify addition of one or more security requirements and/or removal of one or more security requirements from the list of security requirements. A first security vulnerability scan is run using the list of security requirements with the one or more additional security requirements and/or the removed one or more security requirements. Results for the first security vulnerability scan are generated and displayed to a user.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for generating compressed representations of synthetic images. One of the methods is a method of generating a synthetic image using a generative neural network, and includes: generating, using the generative neural network, a plurality of coefficients that represent the synthetic image after the synthetic image has been encoded using a lossy compression algorithm; and decoding the synthetic image by applying the lossy compression algorithm to the plurality of coefficients.

Abstract: Provided is a system (300) for determining a sweat rate per gland and measuring biomarker concentration. The system comprises an apparatus and a sensor (166). The apparatus receives sweat from the skin and transports the sweat as discrete sweat droplets to the sensor. The sensor senses each of the counted sweat droplets. The system further comprises a processor which counts the number of sensed sweat droplets during a time period. The processor also determines time intervals between consecutive sensed sweat droplets, and receives a measure of the volume of each of the counted sweat droplets. The time intervals and the measure of the volume are then used by the processor to identify sweat burst and rest periods of the sweat gland or glands producing the sweat. This identification process necessarily involves assigning the sweat burst and rest periods to the sweat gland or glands, such that the processor is permitted to determine the number of sweat glands involved in producing the sweat.

Abstract: Embodiments of a recombinant human Parainfluenza Virus (hPIV) F ectodomain trimer stabilized in a prefusion conformation are provided. Also disclosed are nucleic acids encoding the hPIV F ectodomain trimer and methods of producing the hPIV F ectodomain trimer. Methods for inducing an immune response in a subject are also disclosed. In some embodiments, the method can be a method for treating or inhibiting a hPIV infection in a subject by administering a effective amount of the recombinant hPIV F ectodomain trimer to the subject.

Abstract: Apparatuses, systems, and methods for open path laser spectroscopy with mobile platforms. An example system may include a first mobile platform and a second mobile platform, each of which supports a payload. A light beam directed from one payload to another may define a measurement path, which may be at a particular height above the ground. The payloads may determine a gas concentration along the measurement path. Wind information at the measurement height may be used to determine a gas flux. One or both of the mobile platforms may then move to a new location, and take a measurement along a new measurement path. By combining the measurement paths, gas flux through a flux surface may be determined.

Abstract: Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.

Abstract: A thermally tempered glass element is provided made of glass with two opposite faces that are under compressive stress of at least 40 MPa. The glass has a working point at which the glass has a viscosity of 104 dPa·s of at most 1350° C. The glass has a viscosity versus temperature profile and a coefficient of thermal expansion versus temperature profile of the glass are such that a variable (750° C.-T13)/(CTELiq-CTEsSol) has a value of at most 5*106 K2. The CTELiq is a coefficient of linear thermal expansion of the glass above a glass transition temperature Tg, the CTESol is a coefficient of linear thermal expansion of the glass in a temperature range from 20° C. to 300° C., and the T13 is a temperature at which the glass has a viscosity of 1013 dPa·s.