Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for generating compressed representations of synthetic images. One of the methods is a method of generating a synthetic image using a generative neural network, and includes: generating, using the generative neural network, a plurality of coefficients that represent the synthetic image after the synthetic image has been encoded using a lossy compression algorithm; and decoding the synthetic image by applying the lossy compression algorithm to the plurality of coefficients.

Abstract: Embodiments of a recombinant human Parainfluenza Virus (hPIV) F ectodomain trimer stabilized in a prefusion conformation are provided. Also disclosed are nucleic acids encoding the hPIV F ectodomain trimer and methods of producing the hPIV F ectodomain trimer. Methods for inducing an immune response in a subject are also disclosed. In some embodiments, the method can be a method for treating or inhibiting a hPIV infection in a subject by administering a effective amount of the recombinant hPIV F ectodomain trimer to the subject.

Abstract: An input regarding security characteristics of a project is received. For example, a security characteristic of a project may be insecure storage of data related to confidentiality. The project is scanned for one or more security requirements based on the received security characteristics. A list of security requirements is built for the project based on the received first input. A machine learning process is used to identify addition of one or more security requirements and/or removal of one or more security requirements from the list of security requirements. A first security vulnerability scan is run using the list of security requirements with the one or more additional security requirements and/or the removed one or more security requirements. Results for the first security vulnerability scan are generated and displayed to a user.

Abstract: The present invention relates to compounds of formula (I) that function as inhibitors of METTL3 (N6-adenosine-methyltransferase 70 kDa subunit) enzyme activity: W—X—Y—Z (I) wherein X, Y and Z are each as defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, and autoimmune diseases, as well as other diseases or conditions in which METTL3 activity is implicated.

Abstract: Provided is a system (300) for determining a sweat rate per gland and measuring biomarker concentration. The system comprises an apparatus and a sensor (166). The apparatus receives sweat from the skin and transports the sweat as discrete sweat droplets to the sensor. The sensor senses each of the counted sweat droplets. The system further comprises a processor which counts the number of sensed sweat droplets during a time period. The processor also determines time intervals between consecutive sensed sweat droplets, and receives a measure of the volume of each of the counted sweat droplets. The time intervals and the measure of the volume are then used by the processor to identify sweat burst and rest periods of the sweat gland or glands producing the sweat. This identification process necessarily involves assigning the sweat burst and rest periods to the sweat gland or glands, such that the processor is permitted to determine the number of sweat glands involved in producing the sweat.

Abstract: Apparatuses, systems, and methods for open path laser spectroscopy with mobile platforms. An example system may include a first mobile platform and a second mobile platform, each of which supports a payload. A light beam directed from one payload to another may define a measurement path, which may be at a particular height above the ground. The payloads may determine a gas concentration along the measurement path. Wind information at the measurement height may be used to determine a gas flux. One or both of the mobile platforms may then move to a new location, and take a measurement along a new measurement path. By combining the measurement paths, gas flux through a flux surface may be determined.

Abstract: Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.

Abstract: Rotary positive displacement machines based on trochoidal geometry and including a helical rotor that undergoes planetary motion relative to a helical stator can be designed and configured so that the axial load or rotor pressure force is positive, negative, or neutral. In some embodiments, a change in axial load, caused by a change in differential pressure across the machine, can be used to trigger a change in a mechanical configuration of the machine.

Abstract: A system and method is disclosed for performing diagnostics on patient devices (720). The patient devices (720) may include respiratory therapy devices that operate in accordance with instruction sets, such as software or firmware. A server (710) may maintain a database of diagnostic data (718) indicating faults in one or more of a plurality of patient devices (720). The server (710) may transmit this diagnostic data (718) to one or more computing devices (760), including identification of faults that have occurred. The server (710) may also transmit service data to the plurality of patient devices (720) in order to address the identified faults.

Abstract: Disclosed are systems and methods for generating graphical displays of analyte data and/or health information. In some implementations, the graphical displays are generating based on a self-referential dataset that are modifiable based on identified portions of the data. The modified graphical displays can indicate features in the analyte data of a host.

Abstract: An example method includes (a) generating a request to obtain log data descriptive of operation of an autonomous vehicle control system in a subject scenario, the log data indexed by an indexing parameter; (b) submitting the request to a log repository service, the log repository service configured to receive the request and serve, responsive to the request, log metadata; (c) loading, based on the log metadata and an index value of the indexing parameter, a log data sketch associated with the index value; and (d) loading, based on the log metadata and the index value, and responsive to an inspection indicator, detailed log data associated with the index value.

Abstract: A glass substrate comprises: a first position, wherein a tensile stress of the glass substrate is insufficient to cause fragmentation of the glass substrate into small pieces upon fracture of the glass substrate; and a second position, wherein the glass substrate is bent relative to the first position, and wherein the tensile stress of the glass substrate is sufficient to cause fragmentation of the glass substrate into small pieces upon fracture of the glass substrate. The glass substrate can include a first surface and a second surface. In the first position, the first surface and the second surface of the glass substrate can be planar. In the second position, the first surface and the second surface of the glass substrate can be planar. The small pieces can be generally cubic. In the second position, the glass substrate can be bent uniaxially along a bend axis of the glass substrate.

Abstract: A system for maintaining a meta-database including meta-data representing decentralized data from source databases, which cause inefficient selection of modeling data and/or variables. Each of source and meta-data interfaces communicate with the respective database(s). A key variable repository module operably couples the databases and includes an AI program with a scanner algorithm and a profiler algorithm. The scanner algorithm receives the source data from the source interface, compresses the data, and synchronizes the data with the meta-data using the meta-database interface. The profiler algorithm receives the meta-data from the meta-database interface, generates granular data types for the meta-data, determines variables indicative of the meta-data, generates variable probability distributions, produces variable associations, and modifies the meta-database to include the probability distributions and associations using the meta-data interface.

Abstract: A thermal enclosure for a computer having a processor and a display is disclosed and may include an inner case. The thermal enclosure may further include a heat sink attached to the inner case and thermally connected to the processor. The heat sink may have an outer heat dissipation channel. The thermal enclosure may also include an outer housing that at least partially the envelops the inner case. The outer housing may have a rear housing portion and a front housing portion. The rear housing portion, the front housing portion, and the outer heat dissipation channel may define a heat dissipation opening that may have an overall width, W, and an overall depth, D, the outer heat dissipation channel may be recessed within the heat dissipation opening and W and D may be adapted to prevent a human finger from coming into contact with the outer heat dissipation channel.

Abstract: An anti-polish ring for an internal combustion engine is provided. The anti-polish ring includes an axially extending ring portion that is configured to scrape a top portion of a piston in a cylinder liner. The anti-polish ring is configured to accommodate passage of an intake or exhaust valve thereby. The anti-polish ring may include an alignment feature so that the anti-polish ring is inserted in a predetermined orientation in the cylinder. The anti-polish ring may include a heat shield and/or a seating member.

Abstract: A system and a method for traffic management on a network. The method including: determining a desired intent for a network operator's traffic; determining a set of classes for a traffic flow through a link; determining a minimum and target bandwidth for each class in the set of class based on the desired intent; measure user score and bandwidth use for each class; allocate a bandwidth per class based on the minimum and target bandwidth and measured user score; and shape the traffic flow to the allocated bandwidth.

Abstract: Devices, methods for analog-to-digital converters (ADCs) that perform high-dynamic range measurements based on optical techniques are disclosed. In one example aspect, an optical encoder includes a polarization rotator configured to receive a train of optical pulses, and an electro-optic (EO) modulator coupled to an output of the polarization rotator. The EO modulator is configured to receive a radio frequency (RF) signal and to produce a phase modulated signal in accordance with the RF signal. The optical encoder also includes a polarizing beam splitter coupled to the output of the EO modulator; and an optical hybrid configured to receive two optical signals from the polarizing beam splitter and to produce four optical outputs that are each phase shifted with respect to one another.

Abstract: Embodiments of the disclosure are drawn to apparatuses and methods for a rotating optical reflector. Optical systems may have a limited field of view, and so in order to expand the area that the optical system collects data from, the field of view of the optical system may be scanned across a target area. The present disclosure is directed to a rotating optical reflector, which includes a transmissive layer which refracts light onto a reflective layer, which has a normal which is not parallel to the axis about which the optical reflector is rotated. The optical reflector may be both statically and dynamically balanced, which may allow an increased size of the optical reflector, which in turn may increase the aperture of an optical system (e.g., a lidar system) using the rotating optical reflector.

Abstract: A joist assembly system that is structured for dynamic retrieval of components, dynamic and precise positioning and location of retrieved components, assembly of the components to form a joist, and delivery of the assembled joist. The joist assembly system has a plurality of material handling systems, a plurality of welding systems, and a rigging table system. The material handling systems are structured to load and position the components such as chords and webs onto the rigging table. The rigging table in turn supports the chords or webs. Subsequently, the plurality of welding systems weld the webs to the chords to form the joist.

Abstract: A compressed unit dose toilet cleaning tablet for use with a wand. The composition contains an anionic surfactant, a carbonate or bicarbonate salt, an organic acid, and about 10% to about 40% by weight polyethylene glycol having molecular weight greater than 3,350. A unit dose of the composition is compressed into a tablet or puck that dissolves in toilet water after cleaning.