Abstract: Methods of treating a Streptococcus pneumoniae infection are described herein.

Abstract: The invention mainly relates to a part for uncoupling a motor and the mounting thereof, which is characterized in that it comprises a rigid connecting part (8) that is to be coaxially placed in the central portion (3) of the core of the stator (2) and includes a central ring (11) for receiving the rotatable shaft of the rotor of the motor (1), from which at least two arms (12) extend, the free ends of which are intended to abut against the inner wall (13) of the core of the stator (2) and form at least two spaces for placing a flexible uncoupling pad (9) that radially extends from the outer surface of the central ring (11) of the rigid connecting part (8), against which the uncoupling pad (9) abuts, to a rigid assembly tab (10) that is to axially extend into the central portion (3) of the core of the stator (2), near the inner surface (13) of said core of the stator (2), while being rigidly connected to the motor mounting (4).

Abstract: When multiple regional data clusters are used to store data in a system, maintaining cache consistency across different regions is important for providing a desirable user experience. In one embodiment, there is a master data cluster where all data writes are performed, and the writes are replicated to each of the slave data clusters in the other regions. Appended to the replication statements are invalidations for cache values for the keys whose values have been changed in the master data cluster. An apparatus in the master data cluster logs replication statements sent to the slave databases. When a slave database fails, the apparatus extracts the invalidations intended for the failed database and publishes the invalidations to a subscriber in the region of the failed database. The subscriber sends the invalidations to the local caches to cause stale data for those keys to be deleted from the caches.

Abstract: A multi-shard database system receives a transaction including multiple actions directed to different shards of the database system. The database system creates a transaction record including a transaction identifier and a transaction status for the transaction in a transaction database. The database system then executes, in parallel, the multiple actions on the different shards by associating with each data item involved in the transaction a data structure that includes the transaction identifier and new data to be applied to the data item. The database system then updates the transaction status in the transaction record for the transaction from pending to completed when each of the multiple actions is successfully executed on the corresponding shard. Consistency is eventually implemented when the data structures associated with the data items involved in the transaction are evaluated. The evaluation of a data structure can be triggered by a read request or other events.

Abstract: Device (3) for the air-cooling of a blower for a heating, ventilation and/or air-conditioning apparatus comprising at least one cooling duct (4) comprising at least one cooling-air inlet (5) and defining a cooling-air-stream flow path (4?) that the cooling-air-stream is at least partially supposed to travel, the duct (4) being delimited by at least one wall, the cooling device (3) being characterized in that the cooling duct (4) comprises at least one cooling-air-stream distribution element (6) arranged in the flow path (4?) of the duct (4).

Abstract: The present invention is in the field of pneumococcal capsular saccharide conjugate vaccines. Specifically, a multivalent Streptococcus pneumoniae immunogenic composition is provided with various conjugated capsular saccharides from different S. pneumoniae serotypes conjugated to 2 or more different carrier proteins, where the composition comprises serotype 19F capsular saccharide conjugated to diphtheria toxoid (DT) or CRM197, optionally wherein 19F is the only saccharide in the composition conjugated to diphtheria toxoid (DT) or CRM197.

Abstract: The present invention is in the field of pneumococcal capsular saccharide conjugate vaccines. Specifically, a multivalent Streptococcus pneumoniae immunogenic composition is provided with various conjugated capsular saccharides from different S. pneumoniae serotypes conjugated to 2 or more different carrier proteins, where the composition comprises serotype 19F capsular saccharide conjugated to diphtheria toxoid (DT) or CRM197, optionally wherein 19F is the only saccharide in the composition conjugated to diphtheria toxoid (DT) or CRM197.

Abstract: The present invention is in the field of pneumococcal capsular saccharide conjugate vaccines. Specifically, an immunogenic composition for infants is provided comprising a multivalent Streptococcus pneumoniae vaccine comprising 2 or more capsular saccharide conjugates from different serotypes, wherein the composition comprises a serotype 22F saccharide conjugate. Such a vaccine may be used in infant populations to reduce the incidence of elderly pneumococcal disease such as exacerbations of COPD and/or IPD.

Abstract: Disclosed is a technology for publishing subscriptions in a publish-subscribe system in accordance with subscription groups. The technology may include (i) determining a consumption characteristic by which each of multiple subscribers in a publish-subscribe system consumes a subscription published by a publisher; (ii) identifying the subscribers whose consumption characteristics satisfy a specified similarity criterion; (iii) defining multiple subscription groups, each of which includes subscriptions of those of the subscribers whose consumption characteristics satisfy the specified similarity criterion; (iv) storing the subscriptions in multiple logical partitions of a storage system where each of the logical partitions contains a separate non-overlapping subset of the subscriptions; and (v) transmitting the subscriptions to the subscribers in accordance with the subscription groups.

Abstract: The invention relates to temperature control equipment (3) for a vehicle, in particular an electric vehicle, enabling an aerothermic adjustment of an airflow to be distributed in a passenger compartment (H) of the vehicle, including at least one heat treatment module (8), capable of heat-treating the airflow, and a distribution module (9), capable of distributing the airflow to the passenger compartment (H). The heat treatment module (8) comprises a single means (21) for heating the airflow to be distributed in the passenger compartment (H), which consists of an electric radiator (21).

Abstract: The invention proposes a device for attaching an actuator (2) to a housing (4), in particular for an automotive vehicle, the actuator being provided for driving a movable equipment (41) disposed within the housing. The device comprises attaching means for attaching the actuator on the housing. The mounting means comprise two conjugated connection flanges (20, 40), respectively mounted on a connexion face (28) of the actuator (28) and on a connection face (48) of the housing. The connexion flanges are adapted to be assembled according to a male/female type connection at the outside of the housing.

Abstract: The invention proposes a device for attaching an actuator (2) to a housing (4), in particular for an automotive vehicle, the actuator being provided for driving a movable equipment (41) disposed within the housing. The device comprises attaching means for attaching the actuator on the housing. The mounting means comprise two conjugated connection flanges (20, 40), respectively mounted on a connexion face (28) of the actuator (28) and on a connection face (48) of the housing. The connexion flanges are adapted to be assembled according to a male/female type connection at the outside of the housing.

Abstract: Methods of treating a Streptococcus pneumoniae infection are described herein.

Abstract: The invention relates to a mount 2 in which is housed an electric motor 3 which has a shaft 10 extending along a longitudinal axis 13, said motor having a mass equilibrium line 22 transverse to the longitudinal axis 13 and passing through a centre of gravity 40 of the electric motor, said mount 2 being connected to the motor 3 by a plurality of decoupling means 20 distributed around the periphery of the motor, characterized in that the longitudinal position D2 with respect to the mount 2 of at least one decoupling means 20 and a dimension D3 of this decoupling means 20 along the longitudinal axis 13 are determined with respect to the mass equilibrium line 22.

Abstract: The present invention relates to a method and an apparatus for fabricating a preform (1,10,100) that can be used for drawing an active optical fiber (8). The present invention further relates to an active optical fiber (8), designed for amplification or attenuation purposes, drawn from said preform (1,10,100) and to an optical amplifier (600, 601) using a laser active optical fiber.

Abstract: The invention relates to a support device (1) of a motor of a blower. The support device (1) comprises a base (2), a ring (3) which extends according to an axis and which is able to house the motor. The support device (1) also comprises at least a decoupling means (4) which connects the base (2) and the ring (3). The ring (3) comprises a first face (5) extending according to the axis and the base (2) comprises a second face (10) extending according to the axis. The decoupling means (4) is interposed between the first (5) and the second (10) faces. The decoupling means may have an “H” shape in order to absorb the vibrations caused by the motor.

Abstract: A breakable coupling device for coupling together first and second main transmission shafts stationary in translation along a longitudinal axis of rotation of the device comprises a blocking device having a discontinuous first housing and a continuous second housing forming a closed loop; a compression device; at least one drive device connecting the blocking device and the compression device together in rotation about the longitudinal axis below a predetermined torque, wherein the discontinuous first housing is configured to receive the at least one drive device below the predetermined torque; and a shifting device configured to shift the at least one drive device non-reversibly from the discontinuous first housing towards the continuous second housing when the torque exerted on the at least one drive device is greater than the predetermined torque.

Abstract: Immunogenic compositions and methods of treating a Streptococcus pneumoniae infection are described herein.

Abstract: A casing (1) is dedicated to housing a heat exchanger (3) in a heating, ventilation and/or air conditioning installation, for example of a motor vehicle. The heat exchanger (3) comprises an air inlet face (12), an air outlet face (13), a rear end face (15), a front end face (14), and at least one side face (16, 17) capped with a radiator tank (4, 5). The casing (1) comprises side walls (18, 19) defining at least one housing to receive at least one part of the radiator tank (4, 5).

Abstract: An assisted control system for controlling the attitude of a rotorcraft comprises a flight control device; at least one control member configured to act on an aerodynamic element of the rotorcraft; a mechanical connection connecting the flight control device to the at least one control member, the mechanical connection including at least one connecting rod moveable in translation, a crank device pivotably disposed about a stationary support shaft passing through the crank device, and a motor including a drive rotor and a stator configured to facilitate a pivoting movement of the crank device about the stationary support; a motor control device configured to control a rotation of the drive rotor relative to the stator; and at least one sensor configured to measure information representative of an operation performed by the flight control device under pilot control and to deliver a signal to the motor control device.