Abstract: The invention relates to an implant for supporting a vertebral column, including at least one attachment element (300) and a connecting rod. Such an attachment element (300) includes an anchoring member (13) in a vertebral body, as well as a head (14) in which a passage opening (15) is provided that is conducive to receiving a connecting rod (12), the attachment element (300) being remarkable in that it comprises a means (316) for centering said rod, said rod-centering means being mounted on a spring-back means (317) placed in said head (14), said centering means (316) and said head (14) being movable relative to each other. A connecting rod (12) capable of being inserted into a passage opening (15) of an attachment element (300) includes at least one second centering surface (19). The attachment element (300) and the connecting rod (12) engage to form an implant in which said rod is rotatably and/or translatably movable relative to the anchoring member (13).

Abstract: The invention relates to an actuator having an (auto)synchronous rotary electric motor and a reversible speed-reducing gearbox coupled to the motor to be driven in rotation thereby An outlet shaft is coupled to the speed-reducing gearbox to be driven in rotation thereby A first angular position sensor and a control circuit are connected to the motor. The circuit delivers a motor power supply signal that varies as a function of a position setpoint signal applied to the control circuit and as a function of signals delivered by the angular position sensor. The gearbox has a plurality of speed-reducing each having a pair of gears mounted to rotate about two parallel axes of rotation.

Abstract: A casing (1) is dedicated to housing a heat exchanger (3) in a heating, ventilation and/or air conditioning installation, for example of a motor vehicle. The heat exchanger (3) comprises an air inlet face (12), an air outlet face (13), a rear end face (15), a front end face (14), and at least one side face (16, 17) capped with a radiator tank (4, 5). The casing (1) comprises side walls (18, 19) defining at least one housing to receive at least one part of the radiator tank (4, 5).

Abstract: A driver alert system for the steering wheel of a motor vehicle. The system comprises an electric motor, an eccentric mass connected to the electric motor, and a control circuit for providing electric supply to the electric motor in response to an alert activation signal The motor is controlled by the control circuit to an operation level of voltage during a portion of a vibration period with a non-vibration period following the vibration period, and the motor is over or under-controlled with respect to the operation range at the beginning or end of said vibration period.

Abstract: A casing (1) is dedicated to housing a heat exchanger (3) in a heating, ventilation and/or air conditioning installation, for example of a motor vehicle. The heat exchanger (3) comprises an air inlet face (12), an air outlet face (13), a rear end face (15), a front end face (14), and at least one side face (16, 17) capped with a radiator tank (4, 5). The casing (1) comprises side walls (18, 19) defining at least one housing to receive at least one part of the radiator tank (4, 5).

Abstract: The present invention relates to an immunogenic composition comprising S. pneumoniae capsular saccharide conjugates from serotypes 19A and 19F wherein 19A is conjugated to a first bacterial toxoid and 19F is conjugated to a second bacterial toxoid. Methods of making and uses thereof are also described.

Abstract: The present invention is in the field of pneumococcal capsular saccharide conjugate vaccines. Specifically, a multivalent Streptococcus pneumoniae immunogenic composition is provided with various conjugated capsular saccharides from different S. pneumoniae serotypes conjugated to 2 or more different carrier proteins, where the composition comprises serotype 19F capsular saccharide conjugated to diphtheria toxoid. Methods of making and uses thereof are also described.

Abstract: The present invention is in the field of pneumococcal capsular saccharide conjugate vaccines. Specifically, an immunogenic composition is provided comprising a multivalent Streptococcus pneumoniae vaccine comprising 13 Streptococcus pneumoniae capsular saccharide conjugates. Methods of making and uses thereof are also described.

Abstract: This intervertebral implant (17) for the human or animal body, suitable for an anterior or posterior location, comprising two relatively rigid pillars (19, 20) connected to each other only by at least two bearing portions (21, 22) able to interact with respective vertebral endplates (7) of the spine, at least one of said bearing portions (21, 22) comprising at least one relatively flexible zone allowing this bearing portion to at least partially conform to the shape of the associated vertebral endplate (7) when said implant (17) is positioned between said two endplates.

Abstract: The present invention is in the field of pneumococcal capsular saccharide conjugate vaccines. Specifically, a multivalent Streptococcus pneumoniae immunogenic composition is provided with various conjugated capsular saccharides from different S. pneumoniae serotypes conjugated to 2 or more different carrier proteins, where the composition comprises serotype 19F capsular saccharide conjugated to diphtheria toxoid (DT) or CRM197, optionally wherein 19F is the only saccharide in the composition conjugated to diphtheria toxoid (DT) or CRM197.

Abstract: A casing houses a heat exchanger in a vehicle HVAC system. The heat exchanger includes air inlet and air outlet faces, rear end and front end faces, and first and second side faces. The side faces are each capped with a radiator tank comprising a front end. Each radiator tank defines an orifice for connection to a heat transfer fluid supply circuit. The casing includes a front end wall defining an opening opposite the front end face of the heat-exchanger. The casing also includes a cover defining at least two passages adapted to suit the orifices of the radiator tanks and fixedly attached to the front end wall. The cover also includes seals for limiting the outlet of air via the opening and/or the passages.

Abstract: The present invention relates to a method and an apparatus for fabricating a preform (1,10,100) that can be used for drawing an active optical fiber (8). The present invention further relates to an active optical fiber (8), designed for amplification or attenuation purposes, drawn from said preform (1,10,100) and to an optical amplifier (600, 601) using a laser active optical fiber.

Abstract: An assisted control system for controlling the attitude of a rotorcraft comprises a flight control device; at least one control member configured to act on an aerodynamic element of the rotorcraft; a mechanical connection connecting the flight control device to the at least one control member, the mechanical connection including at least one connecting rod moveable in translation, a crank device pivotably disposed about a stationary support shaft passing through the crank device, and a motor including a drive rotor and a stator configured to facilitate a pivoting movement of the crank device about the stationary support; a motor control device configured to control a rotation of the drive rotor relative to the stator; and at least one sensor configured to measure information representative of an operation performed by the flight control device under pilot control and to deliver a signal to the motor control device.

Abstract: A breakable coupling device for coupling together first and second main transmission shafts stationary in translation along a longitudinal axis of rotation of the device comprises a blocking device having a discontinuous first housing and a continuous second housing forming a closed loop; a compression device; at least one drive device connecting the blocking device and the compression device together in rotation about the longitudinal axis below a predetermined torque, wherein the discontinuous first housing is configured to receive the at least one drive device below the predetermined torque; and a shifting device configured to shift the at least one drive device non-reversibly from the discontinuous first housing towards the continuous second housing when the torque exerted on the at least one drive device is greater than the predetermined torque.

Abstract: The invention relates to a support device (1) of a motor of a blower. The support device (1) comprises a base (2), a ring (3) which extends according to an axis (A) and which is able to house the motor. The support device (1) also comprises at least a decoupling means (4) which connects the base (2) and the ring (3). The base (2) comprises a first face (11) extending according to the axis (A) and the ring (3) comprises a second face (12) extending according to the axis (A). The decoupling means (4) is interposed between the first (11) and the second (12) face. The decoupling means has an “H” specific shape in order to absorb the vibrations caused by the motor.

Abstract: A driver alert system for the steering wheel of a motor vehicle. The system comprises an electric motor, an eccentric mass connected to the electric motor, and a control circuit for providing electric supply to the electric motor in response to an alert activation signal The motor is controlled by the control circuit to an operation level of voltage during a portion of a vibration period with a non-vibration period following the vibration period, and the motor is over or under-controlled with respect to the operation range at the beginning or end of said vibration period.

Abstract: The invention relates to an actuator (10) comprising: an (auto)synchronous rotary electric motor (11); a reversible speed-reducing gearbox (13) coupled to the motor to be driven in rotation thereby; an outlet shaft (16) coupled to the speed-reducing gearbox to be driven in rotation thereby; a first angular position sensor responsive to the angular position of the outlet shaft; and a control circuit connected to the angular position sensor and to the motor, said the circuit delivering a motor power supply signal that varies as a function of a position setpoint signal applied to the control circuit and as a function of signals delivered by the angular position sensor. The gearbox comprises a plurality of speed-reducing modules or stages (131 to 134), each comprising a pair of gears mounted to rotate about two parallel axes of rotation (17, 160).

Abstract: The present invention is in the field of pneumococcal capsular saccharide conjugate vaccines. Specifically, an immunogenic composition for infants is provided comprising a multivalent Streptococcus pneumoniae vaccine comprising 2 or more capsular saccharide conjugates from different serotypes, wherein the composition comprises a serotype 22F saccharide conjugate. Such a vaccine may be used in infant populations to reduce the incidence of elderly pneumococcal disease such as exacerbations of COPD and/or IPD.

Abstract: The present invention discloses an immunogenic composition comprising S. pneumoniae capsular saccharide conjugates from serotypes 19A and 19F wherein 19A is conjugated to a first bacterial toxoid and 19F is conjugated to a second bacterial toxoid. Vaccines, methods of making vaccines and uses of the vaccines are also described.

Abstract: The present invention is in the field of pneumococcal capsular saccharide conjugate vaccines. Specifically, a multivalent Streptococcus pneumoniae immunogenic composition is provided with various conjugated capsular saccharides from different S. pneumoniae serotypes conjugated to 2 or more different carrier proteins, where the composition comprises serotype 19F capsular saccharide conjugated to diphtheria toxoid (DT) or CRM197, optionally wherein 19F is the only saccharide in the composition conjugated to diphtheria toxoid (DT) or CRM197.