Patents by Inventor Ping Lu

Ping Lu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12362902
    Abstract: A phase-interpolator (PI) circuit generates an interpolated clock to capture data in a capture circuit at a target phase in a phase range between two reference clocks based on an interpolation code within a range of interpolation codes is described. A clamping circuit coupled to the PI circuit provides an interpolation code within a reduced range, where the integral non-linearity (INL) of the interpolated clocks is below a threshold, such that data capture based on the interpolated clock has a lower bit error rate (BER). As a result, the interpolated clock is generated within a reduced phase range corresponding to the reduced range of interpolation codes. When a target phase for an interpolated clock is outside the reduced phase range, the clamping circuit may adjust the target phase clock relative to a reference clock to adjust the target phase to be within the reduced phase range for improved BER.
    Type: Grant
    Filed: November 3, 2023
    Date of Patent: July 15, 2025
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: Ping Lu, Minhan Chen
  • Patent number: 12340152
    Abstract: A large-scale underground shield docking model test platform and a test method using the same are provided. The test platform includes a test soil tank, a partition wall, a shield docking model, and a freezing system. The test soil tank is of an underground foundation pit structure, the partition wall is disposed in the test soil tank to separate the test soil tank into a filling area and a non-filling area. The shield docking model is disposed in the filling area and is a reduced-scale test model. The shield docking model is provided with the freezing system, including a refrigeration system, a coolant circulation system, and freezing pipes. The freezing pipes are arranged on the shield docking model and are connected to the refrigeration system through the coolant circulation system. The refrigeration system is placed on a laminate in the non-filling area of the test soil tank.
    Type: Grant
    Filed: September 30, 2024
    Date of Patent: June 24, 2025
    Assignee: CCCC TUNNEL ENGINEERING CO., LTD.
    Inventors: Zhanhu Yao, Yazhou Zhang, Ping Lu, Yisheng Wang, Hui Li, Lei Zhang, Chi Wei, Xiao Yan, Yuqiang Liang, Yahui Li, Chao Zhang
  • Publication number: 20250182226
    Abstract: The present invention provides a trademark risk management system and method, which is implemented by providing a user-operated electronic device, wherein the electronic device comprises a processor and a network interface controller, a server comprises an application, and the processor connects to the server through the network interface controller to execute the application for the purpose of category recommendation and risk management, especially for the regeneration of text or graphics.
    Type: Application
    Filed: January 17, 2024
    Publication date: June 5, 2025
    Inventors: PENG-CHUN WU, EN-PING LU, VINCENT CHEN
  • Publication number: 20250184623
    Abstract: A machine vision system and method use lensless near-contact imaging with coherent illumination, or incoherent illumination, and high pixel count large format sensors (e.g., equivalent to at least 20 to 65 mega-pixels) to produce diffraction patterns of the micro-objects or the gray scale images of the micro-objects over a large overall field-of-view of the machine vision system. The machine vision system provides feedback to a microassembler system to position, orient, and assemble microscale devices like micro-LEDs over large working areas. The effective resolution of the machine vision system can be further improved through the use of gray scale and super-resolution image processing techniques.
    Type: Application
    Filed: December 5, 2023
    Publication date: June 5, 2025
    Inventors: Patrick Yasuo MAEDA, Jeng PING LU, Eugene CHOW
  • Publication number: 20250182243
    Abstract: A machine vision system and method uses high resolution telecentric, or non-telecentric, machine vision macro lenses with high pixel count large format sensors (e.g., equivalent to at least 20 to 65 mega-pixels) at magnifications that increase the native resolution of the machine vision system, while allowing the overall field-of-view (FOV) of the vision system to be large enough relative to the optics and cameras to enable side-by-side, feathered or staggered stitching of images from individual optical camera modules, which can produce an overall system working FOV image greater than or equal to 12 inches in width. The effective resolution of the machine vision system can be further improved through the use of microlens arrays, gray scale imaging, super-resolution imaging, and pixel shifting.
    Type: Application
    Filed: December 5, 2023
    Publication date: June 5, 2025
    Inventors: Patrick Yasuo MAEDA, Jeng PING LU
  • Patent number: 12313540
    Abstract: One or more embodiments relates to a system for simultaneously detecting vibration and the presence of a target gas having a tunable fiber ring laser in electronic and optical communication with a vibration sensor and a gas detection sensor. One or more embodiments relate to a method for simultaneously measuring vibration and detecting the presence of a target gas in an environment having the steps of providing a system for simultaneously measuring vibration and detecting a target gas into an environment; sending an optical signal to a vibration sensor and gas detection sensor; and collecting and analyzing modified signals from the vibration sensor and gas detection sensor.
    Type: Grant
    Filed: October 17, 2022
    Date of Patent: May 27, 2025
    Assignee: United States Department of Energy
    Inventors: Nageswara Rao Lalam, Michael P. Buric, Ping Lu, Fei Lu, Tao Hong, Ruishu Feng Wright
  • Publication number: 20250150253
    Abstract: A phase-interpolator (PI) circuit generates an interpolated clock to capture data in a capture circuit at a target phase in a phase range between two reference clocks based on an interpolation code within a range of interpolation codes is described. A clamping circuit coupled to the PI circuit provides an interpolation code within a reduced range, where the integral non-linearity (INL) of the interpolated clocks is below a threshold, such that data capture based on the interpolated clock has a lower bit error rate (BER). As a result, the interpolated clock is generated within a reduced phase range corresponding to the reduced range of interpolation codes. When a target phase for an interpolated clock is outside the reduced phase range, the clamping circuit may adjust the target phase clock relative to a reference clock to adjust the target phase to be within the reduced phase range for improved BER.
    Type: Application
    Filed: November 3, 2023
    Publication date: May 8, 2025
    Inventors: Ping LU, Minhan CHEN
  • Publication number: 20250147468
    Abstract: A time-to-digital converter (TDC) circuit generates a digital output indicating a time, known as a phase difference, from a phase of the generated signal to a corresponding phase of a reference signal. The digital output is used by the digitally controlled oscillator (DCO) to correct for the phase/frequency difference to synchronize the generated signal with the reference signal. In an aspect, an adaptive TDC circuit generates a first digital indication in a coarse mode when the offset time is above a threshold and generates a second digital indication in a fine mode when the offset time is below the threshold. The first digital indication and the second digital indication each comprise a same number of bits, and the first digital indication is normalized to the second digital indication for the digital output of the adaptive TDC circuit. A fractional bit may be employed to compensate for a quantization error.
    Type: Application
    Filed: January 13, 2025
    Publication date: May 8, 2025
    Inventors: Ping LU, Minhan CHEN
  • Publication number: 20250141456
    Abstract: In a calibrated digital phase-locked-loop (DPLL) circuit, during a normal operating mode, a control value provided to a digitally controlled oscillator (DCO) is updated by a feedback circuit to keep an output clock generated by the DCO synchronized with a reference clock. The feedback circuit includes a time-to-digital converter (TDC) circuit to measure a phase difference as a time interval. In a calibration operating mode of the calibrated DPLL circuit, calibration of a resolution of a time measurement of the time interval measured by the TDC is performed in the feedback circuit while the control value provided to the DCO is kept constant. Calibrating the TDCs in each of the DPLLs in an integrated circuit (IC) to a nominal resolution in this manner improves synchronization of the clock domains. In some examples, the TDC circuit is a Vernier type circuit and calibration sets a delay difference to a nominal resolution.
    Type: Application
    Filed: October 31, 2023
    Publication date: May 1, 2025
    Inventors: Ping LU, Minhan CHEN, Shaishav A. DESAI
  • Publication number: 20250127783
    Abstract: Disclosed are methods of treating diseases or disorders mediated by dysregulated CDK4/6 and/or Pin 1 activity comprising co-administering a therapeutically effective amount of one or more CDK4/6 inhibitors, and a therapeutically effective amount of one or more Pin1 inhibitors, or a pharmaceutically acceptable salt or salts thereof
    Type: Application
    Filed: September 23, 2022
    Publication date: April 24, 2025
    Applicants: DANA-FARBER CANCER INSTITUTE, INC., BETH ISRAEL DEACONESS MEDICAL CENTER, INC., YEDA RESEARCH AND DEVELOPMENT CO. LTD.
    Inventors: Shizhong KE, Gerburg WULF, Xiao Zhen ZHOU, Nir LONDON, Wenyi WEI, Kun Ping LU, Nathanael S. GRAY, Behnam NABET
  • Patent number: 12264133
    Abstract: Certain substituted urea derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
    Type: Grant
    Filed: October 22, 2021
    Date of Patent: April 1, 2025
    Assignee: CYTOKINETICS, INCORPORATED
    Inventors: Bradley Paul Morgan, Alex Muci, Pu-Ping Lu, Todd Tochimoto, David J. Morgans, Jr., Erica Anne Kraynack
  • Patent number: 12259296
    Abstract: An apparatus, method and system are set forth for detection of fluids using Bragg grating sensors, wherein the Bragg grating sensing element comprises an optical fiber having a Bragg grating inscribed therein characterized by optical properties that are dependent upon the periodicity and effective refractive index of the grating, and a package for subjecting the Bragg grating to a change in strain when contacted by a fluid such that periodicity and effective refractive index of the grating changes, whereby when interrogated with laser light any such change in periodicity and effective refractive index may be detected.
    Type: Grant
    Filed: January 10, 2020
    Date of Patent: March 25, 2025
    Assignee: NATIONAL RESEARCH COUNCIL OF CANADA
    Inventors: Cyril Hnatovsky, Dan Grobnic, Stephen Mihailov, Ping Lu, Kasthuri De Silva, Huimin Ding, David Coulas, Robert Walker
  • Patent number: 12216434
    Abstract: A time-to-digital converter (TDC) circuit generates a digital output indicating a time, known as a phase difference, from a phase of the generated signal to a corresponding phase of a reference signal. The digital output is used by the digitally controlled oscillator (DCO) to correct for the phase/frequency difference to synchronize the generated signal with the reference signal. In an aspect, an adaptive TDC circuit generates a first digital indication in a coarse mode when the offset time is above a threshold and generates a second digital indication in a fine mode when the offset time is below the threshold. The first digital indication and the second digital indication each comprise a same number of bits, and the first digital indication is normalized to the second digital indication for the digital output of the adaptive TDC circuit. A fractional bit may be employed to compensate for a quantization error.
    Type: Grant
    Filed: May 31, 2022
    Date of Patent: February 4, 2025
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: Ping Lu, Minhan Chen
  • Patent number: 12212327
    Abstract: In a calibrated phase-locked loop (PLL), a time-to-digital (TDC) converter circuit can be calibrated to a nominal gain by a calibration circuit to achieve a desired jitter response in the PLL. The TDC circuit in the PLL measures a time difference between the reference clock and a feedback signal as a number of time increments, and the calibration circuit adjusts a resolution of the measurement by adjusting the length of the time increments (i.e., resolution). In a Vernier method employed to measure the time difference, the length of a time increment is determined by a delay difference between a first delay of a first delay circuit in a first series of first delay circuits and a second delay of a second delay circuit in a second series of second delay circuits. Adjusting the resolution of the TDC circuit includes adjusting the delay difference between the first delay and the second delay.
    Type: Grant
    Filed: February 27, 2023
    Date of Patent: January 28, 2025
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: Ping Lu, Bupesh Pandita, Minhan Chen
  • Patent number: 12164144
    Abstract: A method and apparatus for inscribing a Bragg grating in an optical waveguide, comprising: providing electromagnetic radiation from an ultrashort pulse duration laser, wherein the electromagnetic radiation has a pulse duration of less than or equal to 5 picoseconds, and wherein the wavelength of the electromagnetic radiation has a characteristic wavelength in the wavelength range from 150 nanometers (nm) to 2.0 microns (?m): providing cylindrical focusing optics corrected for spherical aberration: providing a diffractive optical element that when exposed to the focused ultrashort laser pulse, creates an interference pattern on the optical waveguide, wherein the irradiation step comprises irradiating a surface of the diffractive optical element with the focused electromagnetic radiation, the electromagnetic radiation incident on the optical waveguide, from the diffractive optical element, being sufficiently intense to cause the permanent change in the index of refraction in the core of the optical waveguide.
    Type: Grant
    Filed: May 13, 2020
    Date of Patent: December 10, 2024
    Assignee: NATIONAL RESEARCH COUNCIL OF CANADA
    Inventors: Cyril Hnatovsky, Nurmemet Abdukerim, Dan Grobnic, Stephen Mihailov, Rune Lausten, Ping Lu, Huimin Ding, David Coulas, Kasthuri De Silva
  • Publication number: 20240382486
    Abstract: Provided are novel pyrimidine dione compounds and pharmaceutically acceptable salts thereof, that are useful for the treatment of hypertrophic cardiomyopathy (HCM) and conditions associated with left ventricular hypertrophy or diastolic dysfunction. The synthesis and characterization of the compounds and pharmaceutically acceptable salts thereof, are described, as well as methods for treating HCM and other forms of heart disease.
    Type: Application
    Filed: February 22, 2024
    Publication date: November 21, 2024
    Inventors: Johan Oslob, Robert Lee Anderson, Danielle L. Aubele, Marc Evanchik, Jonathan Charles Fox, Brian Edmund Kane, Pu-Ping LU, Robert McDowell, Hector Rodriguez, Yonghong Song, Arvinder Sran
  • Publication number: 20240382596
    Abstract: The present invention relates to the technical field of medicine, and in particular, relates to a composition of vancomycin aqueous solution. The pharmaceutical composition contains vancomycin or a pharmaceutically acceptable salt thereof, N-methylalanine, and water. The stability of vancomycin in the state of an aqueous solution can be improved by using N-methylalanine.
    Type: Application
    Filed: June 21, 2022
    Publication date: November 21, 2024
    Applicants: HAINAN POLY PHARM. CO., LTD., ZHEJIANG POLY PHARMACEUTICAL CO., LTD.
    Inventors: Yifan ZHU, Minhua FAN, Ping LU, Zhenkun ZHAO, Cangsu XU, Hui SHI, Le SHEN
  • Patent number: 12141972
    Abstract: A medicine image recognition method applied to an electronic device is provided. The method includes obtaining target images by inputting medicine images into a position detection network. Character feature matrices are generated according to the target images and a character recognition network. Image feature matrices are generated by inputting the target images into a category recognition network. Reference matrices are generated according to the image feature matrices and corresponding character feature matrices. Once a matrix to be tested is generated by processing an image to be tested, and a recognition result of the image to be tested is generated according to a similarity between the matrix to be tested and each of the reference matrices.
    Type: Grant
    Filed: June 20, 2022
    Date of Patent: November 12, 2024
    Assignee: Fulian Precision Electronics (Tianjin) Co., LTD.
    Inventors: Yu-Jen Wang, Meng-Ping Lu
  • Publication number: 20240368091
    Abstract: Provided herein are compounds of formula (I): or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt of any of the foregoing, wherein X1, X2, Ry, Rz, R1, R2, R3, and R4 are as defined herein. Also provided herein is a pharmaceutically acceptable composition comprising a compound of formula (I), or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt of any of the foregoing. Also provided herein are methods of using a compound of formula (I), or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt of any of the foregoing, to treat various diseases, disorders, and conditions responsive to the modulation of the contractility of the skeletal sarcomere.
    Type: Application
    Filed: April 1, 2024
    Publication date: November 7, 2024
    Inventors: Bradley P. MORGAN, Chris EVANS, Pu-Ping LU, Makoto YAMASAKI, Wenyue WANG, Scott COLLIBEE, Takuya MAKINO, Kazuyuki TSUCHIYA, Toshio KUROSAKI, Susumu YAMAKI, Eriko HONJO, Yuka KOIZUMI, Naoto KATOH, Ryuichi SEKIOKA, Ikumi KURIWAKI
  • Publication number: 20240361729
    Abstract: Time-to-digital converters (TDC) employing a single-stage delay pair for a wide input range and reduced quantization noise in a phase-locked loop (PLL) and related fabrication methods are disclosed. Aspects disclosed in the detailed description include a single-stage Vernier time-to-digital converter (TDC) which mitigates the device mismatch impact and therefore avoids possible spurious tones in a fractional-N PLL application. Combined with a delta-sigma noise shaping stage and a ring-oscillator based coarse TDC, the invention achieves a good trade-off between resolution, detection range and PLL locking speed.
    Type: Application
    Filed: April 28, 2023
    Publication date: October 31, 2024
    Inventors: Ping LU, Minhan CHEN