Abstract: Provided is a new-type cis-replicon construct for efficiently expressing a target protein, which comprises an RNA polymerase coding unit and a target protein coding unit. The replicon construct can drive the replication of the target protein coding unit and reduce or avoid the replication and expression of the RNA polymerase, thereby effectively improving the expression of the target protein and reducing the expression of the non-target protein.

Abstract: Implementations of the present disclosure relate to resource unit (RU) assignment to combat frequency selective fading. A method comprises determining, at an access point (AP), a plurality of channel qualities of a plurality of resource units (RUs) for a client. The plurality of RUs are configured to be available for communications with a plurality of clients comprising the client. The method further comprises determining, from the plurality of RUs, a target RU for the client based at least in part on the plurality of channel qualities. The target RU is to be used by the client for a following transmission with the AP. A target RU with good channel quality will be assigned to the client, thus the transmission and overall system performance will be enhanced.

Abstract: A method for evaluating a downhole working condition of a PDC bit includes: performing an indoor test, including performing a drilling test in different full-sized cores by using the PDC bit with different degrees of abrasion and balling under condition of given WOB and rotational speed, to acquire change characteristics of a WOB, a rotational speed, a torque, a ROP and a bit vibration of the PDC bit in different time domains; improving and perfecting an existing prediction model and evaluation method for the downhole working condition through data obtained by the test to obtain the method; reading parameters of the WOB, the rotational speed, the torque and the ROP in real time during drilling; determining the downhole working condition of the PDC bit by using the method in the improving and perfecting.

Abstract: A Pickering particle dry powder and a preparation method are used in food processing. The preparation method includes stirring peanut protein isolate and water as raw materials to obtain peanut protein isolate dispersion, subjecting the peanut protein isolate dispersion to ultrasonic treatment, subjecting the resultant to cross-linking reaction with transglutaminase to obtain a monolithic geld, shearing and homogenizing the monolithic gel to obtain a microgel particle dispersion, spray drying the microgel particle dispersion to obtain the Pickering particle dry powder. The Pickering particle dry powder prepared by the ultrasonic-assisted enzyme method is still in nanometer level after rehydration, which is beneficial to preparing Pickering emulsion with strong stability. The preparation method has the advantages of simple operation and low cost, which is beneficial to actual production in the food industry.

Abstract: Avatar animation systems disclosed herein provide high quality, real-time avatar animation that is based on the varying countenance of a human face. In some example embodiments, the real-time provision of high quality avatar animation is enabled, at least in part, by a multi-frame regressor that is configured to map information descriptive of facial expressions depicted in two or more images to information descriptive of a single avatar blend shape. The two or more images may be temporally sequential images. This multi-frame regressor implements a machine learning component that generates the high quality avatar animation from information descriptive of a subject's face and/or information descriptive of avatar animation frames previously generated by the multi-frame regressor.

Abstract: The present disclosure provides a bispecific antibody including a binding domain that binds to CD112R and a binding domain that binds to TIGIT, and the binding domain that binds to CD112R includes: HCDR1, HCDR2 and HCDR3 of the amino acid sequence set forth in SEQ ID NO: 1, and/or LCDR1, LCDR2 and LCDR3 of the amino acid sequence set forth in SEQ ID NO: 2; and the HCDR1, HCDR2, HCDR3, LCDR1, LCDR2 and LCDR3 are defined according to the Kabat, IMGT, Chothia, AbM or Contact numbering system. The present disclosure further provides a polynucleotide encoding the antibody, an expression vector, a host cell and a method for expressing and purifying the antibody, a pharmaceutical composition including the antibody of the present disclosure, and use of the bispecific antibody for treating cancer.

Abstract: An electric vehicle thermal management system and method based on a self-circulating gas-liquid phase change cold plate are disclosed. A top cover, a first heat exchanger, a battery case partition and a battery case bottom plate are arranged in sequence from top to bottom, a top heat exchanging chamber is formed between an upper heat exchanging surface of the first heat exchanger and the top cover; the battery case partition is of a square wave-like structure, a working medium chamber is formed between a top of the battery case partition and a lower heat exchanging surface of the first heat exchanger, the working medium chamber is filled with a gas-liquid phase change working medium, and a plurality of battery chambers are formed between the bottom of the battery case partition and the battery case bottom plate.

Abstract: A transmission system allowing a window to be opened in three directions includes a door hinge assembly, a guide wheel assembly, a lock assembly, a handle, a first transmission lever, a second transmission lever, an angle converter, a first gear tooth combination, a second gear tooth combination a and a second gear tooth combination b. The angle converter is connected at a position of the first transmission lever and a position of the second transmission lever located at corners of a window sash. The first gear tooth combination is arranged in the handle. The second gear tooth combination a and the second gear tooth combination b are connected to the top and the bottom of the window sash respectively. The lock assemblies are symmetrically provided at two sides of the second gear tooth combination a and the second gear tooth combination b.

Abstract: A solid acid catalyst has a macropore specific volume of about 0.30-0.50 ml/g, a ratio of macropore specific volume to specific length of catalyst particles of about 1.0-2.5 ml/(g·mm), and a ratio of specific surface area to length of catalyst particles of about 3.40-4.50 m2/mm. The macropore refers to pores having a diameter of more than 50 nm. An alkylation catalyst is based on the solid acid catalyst and can be used in alkylation reactions. The solid acid catalyst and alkylation catalyst show an improved catalyst service life and/or trimethylpentane selectivity when used in the alkylation of isoparaffins with olefins.

Abstract: An engine includes a cylinder block, a cylinder head, and a piston. The cylinder head is connected to the cylinder block. The piston is movably connected to the cylinder block. The cylinder block, the cylinder head, and the piston form a combustion chamber. The cylinder head includes an intake valve hole and an exhaust valve hole. An intake valve is disposed at the intake valve hole and an exhaust valve is disposed at the exhaust valve hole. A barrier protrusion is protruded at the edge of the intake valve hole away from the exhaust valve hole. The included angle between a first connecting line connecting a first end of the barrier protrusion and a center of the intake valve hole and a second connecting line connecting a second end of the barrier protrusion and the center of the intake valve hole is greater than 120 degrees and less than or equal to 180 degrees.

Abstract: The present application discloses a display panel and a preparation method thereof, and a display device. The display panel includes a base substrate, and has a display area, a peripheral area surrounding the display area, a hole area located at the display area, and an isolation area located between the hole area and the display area. The display area includes an electroluminescent device located on the base substrate, and a packaging structure for sealing the electroluminescent device, the packaging structure includes an inorganic packaging layer and an organic packaging layer alternately stacked, and the inorganic packaging layer extends to the hole area. The isolation area includes an organic layer located on the inorganic packaging layer.

Abstract: Disclosed are a device and method for detecting defects of a high-voltage cable cross-bonded grounding system. The method comprises: selecting a protective grounding box of a cross-bonded grounding system, respectively connecting a signal excitation coupler to A-phase, B-phase and C-phase coaxial cables of the protective grounding box, selecting a stable signal with a frequency different from a power frequency or a field interference frequency, and testing effective current values and phases responded by the A-phase, B-phase and C-phase coaxial cables when the stable signal with the frequency F1 is injected into the A-phase, B-phase and C-phase coaxial cables of the protective grounding box in a coupled manner; and obtaining resistances and inductances of branch circuits of the cable cross-bonded grounding system by calculation according to measurement data, and determining if the cable cross-bonded grounding system has a connection defect.

Abstract: A system and related method identify a weakness of a workflow in a complex system. The method collects runtime data about the complex system. The complex system comprises a plurality of subcomponents, and the method identifies an abnormal operation in the complex system. The method constructs a multi-dimensional cause-and-effect relation matrix among the plurality of subcomponents, and filters one or more related operations using the multi-dimensional cause-and-effect relation matrix.

Abstract: Disclosed is an express tricycle target object, falling within the field of intelligent connected vehicle (ICV) test equipment. A base plate, vehicle body support plates, two lateral support plates, a vehicle head support plate, several locking mechanisms and skins are included. The vehicle body support plates, the lateral support plates and the vehicle head support plate are assembled into the shape of the express tricycle target object via the locking mechanisms, and different parts of the skins are arranged with wave-absorbing sponges to reduce a radar cross section or with metal substances to enhance a radar cross section, to solve the problem of the insufficient coverage of traffic accident scenes in current tests of the active safety performance of ICVs.

Abstract: Disclosed are an autonomous mobile device and a warehousing logistics system. The autonomous mobile device comprises a sensing assembly, a processor and a driving assembly. The sensing assembly is configured to sense information of an object. The processor is configured to determine whether the object is a movable object according to the information, and to generate a control signal according to a determination result, wherein the control signal is used for indicating an obstacle avoidance distance of the autonomous mobile device. The driving assembly is configured to drive the autonomous mobile device to move, wherein when the object is located on an advancing path of the autonomous mobile device, the driving assembly drives the autonomous mobile device to perform obstacle avoidance by the obstacle avoidance distance at least. The warehousing logistics system comprises a plurality of autonomous mobile devices and a scheduling server.

Abstract: Various aspects of the present disclosure generally relate to wireless communication. In some aspects, a user equipment (UE) may determine that one or more threshold criteria are satisfied, wherein the one or more threshold criteria include at least one of a first value for an uplink grant rate, a second value for a buffer size, or a third value for a packet data convergence protocol discard rate, wherein the one or more threshold criteria relate to a network condition with less than a reference uplink throughput and greater than a reference downlink throughput. The UE may transmit information identifying one or more adjusted measurement values based at least in part on the determination of the one or more threshold criteria. Numerous other aspects are described.

Abstract: Various aspects of the present disclosure generally relate to wireless communication. In some aspects, a user equipment may determine a transmission frequency for an uplink transmission based at least in part on a reference point for the uplink transmission, the reference point being associated with one of: a satellite that provides a cell covering the user equipment, the satellite being associated with a non-terrestrial network, or a gateway associated with the satellite; and transmit the uplink transmission based at least in part on the transmission frequency. Numerous other aspects are provided.

Abstract: Some aspects relate to apparatuses and methods for calculating an uplink pathloss in a wireless communication system. A user equipment (UE) can be configured to perform operations for calculating the uplink pathloss. The operations can include determining a transmission power of a physical uplink shared channel (PUSCH) transmission for a UE, TxpPUSCH, where the PUSCH transmission is from the UE to a base station. The operations can further include determining a receiving power of a sounding reference signal (SRS) by the base station, Rxpsrs; and further calculating the uplink pathloss based on the transmission power of the PUSCH transmission TxpPUSCH and the receiving power of the SRS Rxpsrs.