Abstract: An electronic throttle, including: a throttle housing and, located inside the throttle housing: an electric machine; a torque transfer means; a throttle shaft and a butterfly valve. The throttle shaft passes through a throttle throat, and is supported by being inserted into a first mounting hole and a second mounting hole in the throttle housing, wherein the first mounting hole and the second mounting hole are located in the throttle housing on two sides of the throttle throat respectively, the second mounting hole being located on that side which is closer to the torque transfer means, and the first mounting hole and second mounting hole having inner diameters of the same size. The throttle according to the present device has the advantages of simple component structure, low costs and ease of processing.

Abstract: An image sensor includes a plurality of photodiodes and a floating diffusion disposed in a semiconductor material. The image sensor also includes a plurality of transfer gates coupled between the plurality of photodiodes and the floating diffusion to transfer the image charge generated in the plurality of photodiodes into the floating diffusion. Peripheral circuitry is disposed proximate to the plurality of photodiodes and coupled to receive the image charge from the plurality of photodiodes. A shallow trench isolation structure is laterally disposed, at least in part, between the plurality of photodiodes and the peripheral circuitry to prevent electrical crosstalk between the plurality of photodiodes and the peripheral circuitry. The peripheral circuitry includes one or more transistors including a source electrode and a drain electrode that are raised above a surface of the semiconductor material.

Abstract: An image sensor includes an array of split dual photodiode (DPD) pairs. First groupings of the array of split DPD pairs consist entirely of either first-dimension split DPD pairs or entirely of second-dimension split DPD pairs. Each first grouping of the array of split DPD pairs consisting of the first-dimension split DPD pairs is adjacent to an other first grouping of the array of split DPD pairs consisting of the second-dimension split DPD pairs. The first-dimension is orthogonal to the second-dimension. A plurality of floating diffusion (FD) regions is arranged in each first grouping of the split DPD pairs. Each one of a plurality of transfer transistors is coupled to a respective photodiode of a respective split DPD pair, and is coupled between the respective photodiode and a respective one of the plurality of FD regions.

Abstract: The invention discloses a brake cylinder dust cover and a waterproof brake cylinder using such dust cover. The brake cylinder comprises a brake cylinder body and a front cover. A waterproof dust cover assembly is arranged on the front cover. The waterproof dust cover assembly comprises a dust cover fixedly connected to the front cover, and a filter felt support and a filter felt pad which are arranged in the dust cover. The filter felt support is connected with the dust cover, and the filter felt pad is fixed on the filter felt support. An outwards extending skirt is arranged at the edge of the dust cover in the axial direction thereof.

Abstract: The disclosure relates to a pharmaceutical combination of a mdm2/4 inhibitor, namely (S)-1-(4-Chloro-phenyl)-7-isopropoxy-6-methoxy-2-(4-{methyl-[4-(4-methyl-3-oxo-piperazin-1-yl)-trans-cyclohexylmethyl]-amino}-phenyl)-1,4-dihydro-2H-isoquinolin-3-one or (S)-5-(5-Chloro-1-methyl-2-oxo-1,2-dihydro-pyridin-3-yl)-6-(4-chloro-phenyl)-2-(2,4-dimethoxy-pyrimidin-5-yl)-1-isopropyl-5,6-dihydro-1H-pyrrolo[3,4-d]imidazol-4-one, and a cyclin dependent kinase 4/6 (CDK4/6) inhibitor 7-Cyclopentyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid dimethylamide. In addition, the disclosure relates to a pharmaceutical combination product. The disclosure also relates to corresponding pharmaceutical formulations, uses and treatment methods comprising said mdm2/4 inhibitor or a cyclin dependent kinase 4/6 (CDK4/6) inhibitor.

Abstract: A real-time, on-line method and analytical system for determining halohydrocarbons in water which operate by (1) extracting on-line samples; (2) purging volatile halohydrocarbons from the water (e.g., with air or nitrogen); (3) carrying the purge gas containing the analytes of interest over a porous surface where the analytes are adsorbed; (4) recovering the analytes from the porous surface with heat (thermal desorption) or solvent (solvent elution) to drive the analytes into an organic chemical mixture; (5) generating an optical change (e.g., color change) in dependence upon a reaction involving the analytes and a pyridine derivative; and (6) measuring optical characteristics associated with the reaction to quantify the volatile halogenated hydrocarbon concentration.

Abstract: Methods and systems for producing prescribed unit size poly(3-hydroxyalkanoate) (PHA) polymers and copolymers are provided. The methods and systems can employ recombinant bacteria that are not native producers of PHA or lack enzymes to degrade PHA once synthesized, metabolize short to long chain fatty acids without induction, and express an (R)-specific enoyl-CoA hydratase and a PHA synthase, the (R)-specific enoyl-CoA hydratase and PHA synthase having wide substrate specificities. The recombinant bacteria are fed at least one fatty acid substrate that is equal in carbon length to the prescribed or desired unit size of the PHA polymer to be produced. The prescribed unit size PHA that is produced is then isolated and/or purified.

Abstract: A pharmaceutical combination comprising (a) an ALK inhibitor, or a pharmaceutically acceptable salt thereof, and (b) at least one HDMA-2/p53 receptor inhibitor or a pharmaceutically acceptable salt, or at least one BRaf inhibitor or a pharmaceutically acceptable salt, and optionally a pharmaceutically acceptable carrier, for simultaneous, separate or sequential administration; the uses of such combination in the treatment of cancer; and methods of treating a subject suffering from a proliferative disease comprising administering a therapeutically effective amount of such combination.

Abstract: An image sensor includes a semiconductor material including a plurality of photodiodes disposed in the semiconductor material. The image sensor also includes a first insulating material disposed proximate to a frontside of the semiconductor material, and an interconnect disposed in the first insulating material proximate to the frontside of the semiconductor material. A metal pad extends from a backside of the semiconductor material through the first insulating material and contacts the interconnect. A metal grid is disposed proximate to the backside of the semiconductor material, and the semiconductor material is disposed between the metal grid and the first insulating material disposed proximate to the frontside.

Abstract: A speaker assembly comprises two separate and symmetrical speakers combining together in a reversed manner. Each speaker includes a base surface for seating said speaker and a sound emission surface provided at one front side thereof for an emission of sound derived from the speaker. Wherein each speaker defines a mating surface which the sound emission surface is located at and said two speakers can be secured to each other snugly into an integral unit by jointing two mating surfaces thereof via a magnetic force.

Abstract: An image sensor includes a substrate, a plurality of light sensitive pixels, a first plurality of color filters, a plurality of reflective sidewalls, and a second plurality of color filters. The light sensitive pixels are formed on said substrate. The first plurality of color filters is disposed over a first group of the light sensitive pixels. The reflective sidewalls are formed on each side of each of the first plurality of color filters. The second plurality of color filters are disposed over a second group of light sensitive pixels and each color filter of the second plurality of color filters is separated from each adjacent filter of said first plurality of color filters by one of the reflective sidewalls. In a particular embodiment an etch-resistant layer is disposed over the first plurality of color filters and the second group of light sensitive pixels.

Abstract: An image sensor includes a semiconductor material including a plurality of photodiodes disposed in the semiconductor material. The image sensor also includes a first insulating material disposed proximate to a frontside of the semiconductor material, and an interconnect disposed in the first insulating material proximate to the frontside of the semiconductor material. A metal pad extends from a backside of the semiconductor material through the first insulating material and contacts the interconnect. A metal grid is disposed proximate to the backside of the semiconductor material, and the semiconductor material is disposed between the metal grid and the first insulating material disposed proximate to the frontside.

Abstract: A camera system has a lens focusing incoming light through a deflector system having at least one deflector plate onto a photosensor array. An image processor captures at least a first image with the deflector system in a first position and a second image with the deflector system in a second position to provide a focal point offset in a first axis on the photosensor array, and the firmware is configured to prepare an enhanced image from at least the first and second images. A method of imaging includes focusing incoming light through a deflector system having at least one deflector plate onto a photosensor array; receiving at least a first image with the deflector system in a first position; receiving a second image with the deflector system configured providing a focal point offset on the photosensor array; and preparing an enhanced image from the first and second images.

Abstract: A speaker assembly comprises two separate and symmetrical speakers combining together in a reversed manner. Each speaker includes a base surface for seating said speaker and a sound emission surface provided at one front side thereof for an emission of sound derived from the speaker. Wherein each speaker defines a mating surface which the sound emission surface is located at and said two speakers can be secured to each other snugly into an integral unit by jointing two mating surfaces thereof via a magnetic force.

Abstract: The disclosure relates to a pharmaceutical combination of a mdm2/4 inhibitor, namely (S)-1-(4-Chloro-phenyl)-7-isopropoxy-6-methoxy-2-(4-{methyl-[4-(4-methyl-3-oxo-piperazin-1-yl)-trans-cyclohexylmethyl]-amino}-phenyl)-1,4-dihydro-2H-isoquinolin-3-one or (S)-5-(5-Chloro-1-methyl-2-oxo-1,2-dihydro-pyridin-3-yl)-6-(4-chloro-phenyl)-2-(2,4-dimethoxy-pyrimidin-5-yl)-1-isopropyl-5,6-dihydro-1H-pyrrolo[3,4-d]imidazol-4-one, and a cyclin dependent kinase 4/6 (CDK4/6) inhibitor 7-Cyclopentyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid dimethylamide. In addition, the disclosure relates to a pharmaceutical combination product. The disclosure also relates to corresponding pharmaceutical formulations, uses and treatment methods comprising said mdm2/4 inhibitor or a cyclin dependent kinase 4/6 (CDK4/6) inhibitor.

Abstract: Methods and systems for producing prescribed unit size poly(3-hydroxyalkanoate) (PHA) polymers and copolymers are provided. The methods and systems can employ recombinant bacteria that are not native producers of PHA or lack enzymes to degrade PHA once synthesized, metabolize short to long chain fatty acids without induction, and express an (R)-specific enoyl-CoA hydratase and a PHA synthase, the (R)-specific enoyl-CoA hydratase and PHA synthase having wide substrate specificities. The recombinant bacteria are fed at least one fatty acid substrate that is equal in carbon length to the prescribed or desired unit size of the PHA polymer to be produced. The prescribed unit size PHA that is produced is then isolated and/or purified.

Abstract: A vehicle position detecting method comprises: continuously detecting a detection region and generating a sensing signal by a sensor (S100); continuously determining whether a sudden change exists in the sensing signal, and starting timing when the sensing signal suddenly changes (S200); terminating timing after a preset time, if the sensing signal received at an end of timing does not restore to the sensing signal prior to the sudden change, confirming a vehicle is or is not in the detection region (S300); the sudden change is defined as a variation of the sensing signal per unit time exceeding a preset range. A vehicle position detecting system is also provided.

Abstract: The present invention discloses a method for preparing a catalyst, comprising the following steps: (1) taking a noble metal salt solution A, adding a modified alumina support material, stirring until uniform and standing; (2) drying the material obtained in step (1) in a vacuum, and calcining at 500° C.-600° C. for 1-4 hours to obtain a powder material containing the noble metal; (3) mixing the noble metal powder material, an adhesive and other components to be added, and ball-milling to obtain a uniform slurry; (4) preparing a noble metal solution B and adjusting pH to 0.5-1; and (5) mixing the slurry of the step (3) with the noble metal solution B, coating the mixture on a support, drying, and calcining at 500° C.-600° C. for 1-2 hours to obtain the target product. The method for preparing the catalyst of the present invention is simple, the conditions of the preparation process are easy to control and the preparation method has strong practicality.

Abstract: An air-tight door system and a control method therefor. The air-tight door comprises a first door (M1), a second door (M2), a first door detection module (S1, S2, P1), a second door detection module (S3, S4, P2) and a controller (K). The air-tight door control method comprises: the first and second detection modules (S1, S2, P1, S3, S4, P2) detect whether the first door (M1) and the second door (M2) are completely closed; and the controller (K) controls opening and closing of the first door (M1) and the second door (M2) according to whether the first and second doors (M1, M2) are completely closed. The air-tight door system and the control method therefor ensure that at least one door is in the closed state at any time, thereby further improving air-tightness and device safety.

Abstract: This invention relates to oral care compositions comprising a basic amino acid or salt thereof, and a small particle fraction: and to methods of using and of making these compositions.