Abstract: A class of polycyclic compounds of general formula (I), of general formula (I?), or of general formula (I?), wherein Base1, Base2, Y, Ya, Xa, Xa1, Xb, Xb1, Xc, Xc1, Xd, Xd1, R1, R1a, R2, R2a, R3, R4, R4a, R5, R6, R6a, R7, R7a, R8, and R8a are defined herein, that may be useful as inductors of type I interferon production, specifically as STING active agents, are provided. Also provided are processes for the synthesis and use of compounds.

Abstract: Computer-implemented systems and methods for processing a document package are disclosed. A method for processing a document may include analyzing one or more documents to determine potential signer information, determining on such information, a respective set of signers, and sending electronic notifications to the signers. The notifications may include selectable links configured to provide access to the electronic documents associated with the signers. Upon selection of a link, an interactive user interface may be provided including access to the electronic documents. Signature data from a signer may be received via the interactive user interface. Based on the signature data, the system may determine whether completion criteria associated with the one or more documents is satisfied; in response to the completion criteria being satisfied, further electronic notifications to at least the signers may be sent out.

Abstract: Methods and systems for compact presentation of automatically summarized information according to rule-based graphically represented information. One of the methods includes obtaining, via a user accessible user interface, a request for uploaded textual information to be analyzed. Ontology information is accessed based on an indicated type associated with the textual information, and ontology information for the type. The ontology information specifies nodes, with the nodes causing the server system to extract values for textual expressions defined by the nodes, and relational information between the nodes, with the relational information indicating links between textual expressions. The textual information is parsed based on the ontology information. The parsing causes traversal of the nodes and extraction of values from associated textual expressions based on the textual information. Values are obtained based on the parsing, with the values being utilized as summary information.

Abstract: A bushing assembly for use in a vehicle suspension system includes an outer sleeve, with an elastomeric element at least partially positioned within the outer sleeve. An inner sleeve is at least partially positioned within the elastomeric element, while a bar pin having a central section is at least partially positioned within the inner sleeve. A retaining ring is positioned at or adjacent to a first end of the central section of the bar pin and at least partially within the outer sleeve. The retaining ring is positioned between the inner sleeve and at least one radially enlarged section at the first end of the central section of the bar pin and/or at least one radially inwardly directed section at a first end of the outer sleeve.

Abstract: A class of polycyclic compounds of general formula (II), of general formula (II?), or of general formula (II?), wherein Base1, Base2, Y, Ya, Xa, Xa1, Xb, Xb1, Xc, Xc1, Xd, Xd1, R1, R1a, R2, R2a, R3a, R4, R4a, R5, R6, R6a, R7, R7a, R8, and R8a are defined herein, that may be useful as inductors of type I interferon production, specifically as STING active agents, are provided. Also provided are processes for the synthesis and use of compounds.

Abstract: The field of the invention is oil sands processing. A solvent treatment system and process for treating a bitumen-containing stream include contacting that stream with a solvent-containing stream to produce an in-line flow of solvent diluted material; supplying the solvent diluted material into a separation vessel with axi-symmetric phase and velocity distribution and/or particular mixing and conditioning features. The solvent addition, mixing and conditioning may be performed with particular Co V, Camp number, co-annular pipeline reactor, pipe wall contact of low viscosity fluid, flow diffusing and/or flow straightening. The processes enable improved performance of downstream unit operations such as separation of high diluted bitumen from solvent diluted tailings.

Abstract: A parallel diagnostic/software installation system includes a computing device, a server device storing computing device software, and a software staging device that is coupled to the server device through a first connection that provides a first maximum transmission rate, and that is coupled to the computing device through a second connection that provides a second maximum transmission rate that is faster than the first transmission maximum rate. The software staging device receives a manifest of computing device software for installation on the computing device and then retrieves, from the server device through the first connection, at least a portion of the computing device software while the computing device is performing a diagnostic test on a first hardware configuration of the computing device. The software staging devices determines that the diagnostic test has completed and, in response, provides, to the computing device through the second connection, the computing device software.

Abstract: The present application is directed to a system and method for allocating a Track in a 6T1SCH network. The method includes the step of receiving a Track computation request in PCEP from a first PCE proxy on a first Backbone router. The method also includes the step of calculating an optimal Track between a source LLN device and a destination LLN device. Further, the method includes the step of sending a Track assignment message to one or more LLN devices in the optimal Track. The present application also is directed to a system and method for reporting TSCH schedule information to a PCE. Further, the present application is directed to a LLN device.

Abstract: In various examples there is a telecommunications network access point of a telecommunications network in which the control plane is implemented using a data center comprising a plurality of interconnected computation nodes. The access point comprises a memory holding a log of encapsulated control messages the control messages being messages of a control protocol of the telecommunications network. The access point has a processor configured, for a control message to be sent by the access point to a node in the data center, to: generate a message identifier; encapsulate the control message in a packet of a communications protocol of the data center, add the message identifier to a header of the encapsulated control message; send the encapsulated control message to the node of the data center; and store a record of the encapsulated control message and node of the control plane in the log.

Abstract: A system including a motion adaptive de-interlacer, a film mode detector, and a combiner. The motion adaptive de-interlacer is configured to determine a first output by de-interlacing a plurality of interlaced frames based on at least a first motion indicator indicating motion between fields of the plurality of interlaced frames. The film mode detector is configured to determine a second output based on a film mode detected based on at least a second motion indicator indicating motion between fields of the plurality of interlaced frames. The film mode detector is further configured to output a control signal based on the second motion indicator and the film mode. The combiner is configured to combine the first output and the second output based on the control signal.

Abstract: Disclosed herein are system, method, and computer program product embodiments for identity-based internet protocol networking. An embodiment operates by receiving a packet from a device of a secured network. A strength of authentication of the device is determined based on how a user account associated with the device is authenticated. A policy corresponding to the strength of authentication is determined. The packet is transmitted based upon the policy.

Abstract: A method and apparatus for performing an assembly operation. A tool may be macro-positioned relative to an exterior of a fuselage assembly. The tool may be micro-positioned relative to a particular location on the exterior of the fuselage assembly. An end effector is removably associated with an external robotic device associated with an external mobile platform. The tool is removably associated with the end effector. An assembly operation may be performed at the particular location on the panel using the tool.

Abstract: The present invention relates to purified and isolated DNA sequences having protein production increasing activity and more specifically to the use of matrix attachment regions (MARs) for increasing protein production activity in a eukaryotic cell. Also disclosed is a method for the identification of said active regions, in particular MAR nucleotide sequences, and the use of these characterized active MAR sequences in a new multiple transfection method.

Abstract: A cloud-based DNS-SD architecture may link together separate LANs to form a virtual discovery zone from a service discovery perspective that includes a cloud based DNS-SD server separate from regular Internet DNS, and asleep node handling, among other things. In an example, a cloud based DNS-SD server is separate from the regular Internet DNS servers. This cloud DNS-SD server may run as a private Infrastructure as a Service (IaaS) specifically for service discovery in the virtual discovery zone.

Abstract: An approach is provided in which an emergency electrical distribution system detects an environmental alert invoked by an environmental sensor located in a particular location of building structure. The emergency electrical distribution system selects specific electrical source connections in proximity to the environmental sensor and, in turn, terminates electrical power to selected specific electrical source connections.

Abstract: A switching device is disclosed. The switching device includes a spin-orbit coupling (SOC) layer, a pure spin conductor (PSC) layer disposed atop the SOC layer, a ferromagnetic (FM) layer disposed atop the PSC layer, and a normal metal (NM) layer sandwiched between the PSC layer and the FM layer. The PSC layer is a ferromagnetic insulator (FMI) is configured to funnel spins from the SOC layer onto the NM layer and to further provide a charge insulation so as to substantially eliminate current shunting from the SOC layer while allowing spins to pass through. The NM layer is configured to funnel spins from the PSC layer into the FM layer.

Abstract: Embodiments concern a dynamic authorization framework. Security Classification Process (SCP) is the process of classifying raw data, information extracted from raw data, content or code from security-value perspective. Security Achievability Determination Process (SADP) is a process based on a SV/SC that has been assigned, the RHE may determine the Security Requirements and how the security requirements may be achieved. During the Security Achievability Listing Process (SALP), the RHE uploads onto the Resource Listing Entity (RLE) the URI of the resource, the SAM associated with the resource and optionally a digital certificate associated with the resource. During the SAM Assessment Process (SAMAP) process, a Client evaluates the security mechanisms that must be carried out in order to meet the SAM that was provided as part of the Discovery Process (DP). Based on the SAM obtained from the RLE, the Client may initiate a Security Achievability Enabling Process (SAEP).

Abstract: Methods and procedures allow devices interwork with various types of service layers by updating the device to support the protocol of the M2M/IoT service layer that is being communicated with. Devices can coordinate/initiate download of a service layer API that is compatible with the service layer the device is attempting to use. A service layer can coordinate the autonomous update of a device with the proper service layer API which allows the device to then communicate and use services supported by the service layer component to the device. A service layer can detect a device or application lacking proper service layer functionality and can trigger a management entity to update the device or application with the service layer API required such that the device can then register to the service layer and use its services. A device or application can be customized or optimized to the service layer that it is registered to and using.

Abstract: A vascular remodeling device is provided. The device has an anchor portion, sized for deployment in a blood vessel, that is radially expandable from a collapsed state to an expanded state. The device also includes a distal portion sized for deployment in a blood vessel. The distal portion is radially expandable from a collapsed state to an expanded state and has a distal face that is sufficiently occlusive in the distal-to-proximal direction to perform a therapeutic blocking function in an aneurysm neck. The device also has an intermediate portion that interconnects a distal end of the anchor portion and a proximal end of the distal portion. In some embodiments, the anchor portion and/or distal portion has a plurality of interconnected struts.