Abstract: An example of a method includes providing a substrate with an exposed surface comprising a first chemical group, wherein the providing optionally comprises modifying the exposed surface of the substrate to incorporate the first chemical group; reacting the first chemical group with a first reactive group of a functionalized polymer molecule to form a functionalized polymer coating layer covalently bound to the exposed surface of the substrate; grafting a primer to the functionalized polymer coating layer by reacting the primer with a second reactive group of the functionalized polymer coating layer; and forming a water-soluble protective coating on the primer and the functionalized polymer coating layer. Examples of flow cells incorporating examples of the water-soluble protective coating are also disclosed herein.

Abstract: Described herein are flexible implantable occluding devices that can, for example, navigate the tortuous vessels of the neurovasculature. The occluding devices can also conform to the shape of the tortuous vessels of the vasculature. In some embodiments, the occluding devices can direct blood flow within a vessel away from an aneurysm or limit blood flow to the aneurysm. Some embodiments describe methods and apparatus for adjusting, along a length of the device, the porosity of the occluding device. In some embodiments, the occluding devices allows adequate blood flow to be provided to adjacent structures such that those structures, whether they are branch vessels or oxygen-demanding tissues, are not deprived of the necessary blood flow.

Abstract: A vascular remodeling device has a plurality of sections, sized for deployment in a blood vessel, that is radially expandable from a collapsed state to an expanded state. Each section has a plurality of interconnected struts that define a waist, a proximal face, and a distal face. Each face comprises (i) a plurality of distal strut portions extending proximally from a distal side of the face, (ii) a plurality of proximal strut portions extending distally from a proximal side of the face, and (iii) a plurality of sub-struts, wherein, from each proximal strut portion, two of the sub-struts each extend to a different one of the distal strut portions.

Abstract: Systems and methods for conducting designated reactions utilizing a base instrument and a removable cartridge. The removable cartridge includes a fluidic network that receives and fluidically directs a biological sample to conduct the designated reactions. The removable cartridge also includes a flow-control valve that is operably coupled to the fluidic network and is movable relative to the fluidic network to control flow of the biological sample therethrough. The removable cartridge is configured to separably engage a base instrument. The base instrument includes a valve actuator that engages the flow-control valve of the removable cartridge. A detection assembly held by at least one of the removable cartridge or the base instrument may be used to detect the designated reactions.

Abstract: A method of predicting an output of oil and gas production in a hydrocarbon reservoir of a current and future producing well using a neural network model, includes receiving a data set comprising a plurality of parameters of the hydrocarbon reservoir at a wellsite. The method also includes using the data set to generate a plurality of simulation curves of the hydrocarbon reservoir, each parameter of the plurality of parameters has a range, and the range is adjustable, and the wellsite includes a wellbore penetrating a subterranean formation to extract reserves from the hydrocarbon reservoir. The method also includes performing a simulation, based on the range of each said parameter of the plurality of parameters, of the hydrocarbon reservoir. The method also includes downloading the plurality of simulation curves into a local server to prepare training data for training the neural network model.

Abstract: Systems and methods for conducting designated reactions utilizing a base instrument and a removable cartridge. The removable cartridge includes a fluidic network that receives and fluidically directs a biological sample to conduct the designated reactions. The removable cartridge also includes a flow-control valve that is operably coupled to the fluidic network and is movable relative to the fluidic network to control flow of the biological sample therethrough. The removable cartridge is configured to separably engage a base instrument. The base instrument includes a valve actuator that engages the flow-control valve of the removable cartridge. A detection assembly held by at least one of the removable cartridge or the base instrument may be used to detect the designated reactions.

Abstract: The present invention is an improved lithium-ion battery core system for use within an electric vehicle. The present invention has a battery receiver and a battery charger. The battery receiver has a battery adaptor and a receiver lock. The battery adaptor allows the present invention to insert standardized lithium-ion cores that are managed at a specified voltage level suitable for the electric vehicle. The lithium-ion core includes a removable and rechargeable lithium-ion core, that can be charged by the battery charger. The battery charger has a plurality of cores, a plurality of lights, and an ejection button. The ejection button removes a battery from the battery charger. All of these various components allow for the present invention to provide users with a system for keeping electric vehicles properly charged for long distance travel.

Abstract: A method of reducing blood flow within an aneurysm includes: injecting a contrast agent into a blood vessel including an aneurysm; expanding a stent, from a delivery device, across the aneurysm; and confirming that a stagnated area forms in the aneurysm. The stagnated area can form a crescent shape, a mushroom shape, a hemispherical shape, and/or a flat side. Upon confirming that the stagnated area forms in the aneurysm, the delivery device can be withdrawn from the blood vessel. The stagnated area can include the contrast agent. If the stagnated area does not form in the aneurysm, a second occluding device may be deployed. After withdrawing the delivery device, substantially all of the aneurysm progressively thromboses.

Abstract: A semiconductor package includes an interposer, a number of a first integrated circuit (IC) dies, one or more second IC dies, and one or more dummy dies. The first IC dies, the second IC dies and the dummy dies are implemented on the interposer. The dummy dies are configured to enable routing of pins of the first IC dies to selected circuits of the second IC dies while conforming to predefined routing rules.

Abstract: A catheter or shaft, such as a distal access support or aspiration catheter, is provided that is configured to be advanced at least partially within a patient. The catheter or shaft may include a flexible and hollow shaft including a proximal end and a distal end. The flexible and hollow shaft may include a slotted portion with a plurality of slotted openings, the slotted portion including a first segment with a first pattern of slotted openings and a second segment extending proximally relative the first segment with a second pattern of slotted openings different from the first pattern.

Abstract: The present invention relates to a method and a system for wireless communication. A method and a system according to the present invention is implemented by a node, a gateway, and a server. The nodes and the gateway communicating with each other via an improved LoRaWAN protocol for extending further functions of the gateway, such as data processing or the same, result in computing requirements decreasing at the server, reducing in time and several communicating procedures among network components, thus enhancing the efficiency for using network resources.

Abstract: The present invention relates to a gateway for use in wireless communication. The gateway according to the present invention is to wireless communicate with nodes and a server. The nodes and the gateway communicating with each other via an improved LoRaWAN protocol for extending further functions for the gateway, such as data processing or the same, result in computing requirements decreased at the server, reducing in time and several communicating procedures among network components, thus enhancing the efficiency for using network resources.

Abstract: A semiconductor package includes an interposer, a number of a first integrated circuit (IC) dies, one or more second IC dies, and one or more dummy dies. The first IC dies, the second IC dies and the dummy dies are implemented on the interposer. The dummy dies are configured to enable routing of pins of the first IC dies to selected circuits of the second IC dies while conforming to predefined routing rules.

Abstract: The invention relates generally to methods and systems for capturing, filtering, or retrieving obstructions or other particulates from a patient's vasculature. It may relate to integrated thrombectomy and filtering devices and methods of use. The methods and systems may be configured to remove obstructions such as clots or foreign body objects from a neurovascular vessel or other vasculature and/or provide protection from distal emboli. In one aspect, device for retrieving an obstruction from a patient is provided that includes an outer delivery shaft and an expandable basket movable between a collapsed configuration and an expanded configuration. The basket is configured to be in the collapsed configuration during delivery and in the expanded configuration during engagement and retrieval of the obstruction. A proximal end of the basket is configured to be centrally and pivotally coupled to the outer delivery shaft.

Abstract: An interposer for a flow cell comprises a base layer having a first surface and a second surface opposite the first surface. The base layer comprises black polyethylene terephthalate (PET). A first adhesive layer is disposed on the first surface of the base layer. The first adhesive layer comprises methyl acrylic adhesive. A second adhesive layer is disposed on the second surface of the base layer. The second adhesive layer comprises methyl acrylic adhesive. A plurality of microfluidic channels extends through each of the base layer, the first adhesive layer, and the second adhesive layer.

Abstract: The invention relates generally to methods and systems for capturing, filtering, or retrieving obstructions or other particulates from a patient's vasculature. In one aspect, a device for retrieving an obstruction from a patient is provided that includes an outer delivery shaft and an expandable basket movable between a collapsed configuration and an expanded configuration. The basket is configured to be in the collapsed configuration during delivery and in the expanded configuration during engagement and retrieval of the obstruction. A proximal end of the basket is configured to be centrally and pivotally coupled to the outer delivery shaft. The proximal end and/or a distal end of the basket is movable relative to each other such that a proximal portion of the expandable basket is invertible toward a distal portion of the basket to form a proximally oriented cavity in the expanded configuration to engage and retrieve the obstruction.

Abstract: A catheter or shaft, such as a distal access support or aspiration catheter, is provided that is configured to be advanced at least partially within a patient. The catheter or shaft may include a flexible and hollow shaft including a proximal end and a distal end. The flexible and hollow shaft may include a slotted portion with a plurality of slotted openings, the slotted portion including a first segment with a first pattern of slotted openings and a second segment extending proximally relative the first segment with a second pattern of slotted openings different from the first pattern.

Abstract: A method of calibrating an Advanced Driver Assistance System (ADAS) sensor on a vehicle includes receiving a signal at a handheld vehicle diagnostic tool from an onboard vehicle computer, with the signal including a list of ADAS sensors located on the vehicle. The list is displayed on the diagnostic tool and user input is received on the diagnostic tool identifying a selected ADAS sensor from the list. Calibration instructions associated with the selected ADAS sensor are displayed in response to receiving the user input. An image is projected onto a projection surface adjacent the vehicle, with the projected image being associated with calibrating the selected ADAS sensor. Computer executable instructions are executed on the diagnostic tool to autonomously calibrate the selected ADAS sensor using the projected image in response to receipt of the user input and projecting the image onto the projection surface.

Abstract: An IC assembly including an exposed pad integrated circuit (“IC”) package having a thermal pad with a top surface and a bottom surface and with at least one peripheral surface portion extending transversely of and continuous with the bottom surface. The bottom surface and the at least one peripheral surface are exposed through a layer of mold compound. Also, methods of making an exposed pad integrated circuit (“IC”) package assembly. One method includes optically inspecting a solder bond bonding a thermal pad of an exposed pad IC package to a printed circuit board. Another method includes wave soldering an exposed pad of an IC package to a printed circuit board.

Abstract: An IC assembly including an exposed pad integrated circuit (“IC”) package having a thermal pad with a top surface and a bottom surface and with at least one peripheral surface portion extending transversely of and continuous with the bottom surface. The bottom surface and the at least one peripheral surface are exposed through a layer of mold compound. Also, methods of making an exposed pad integrated circuit (“IC”) package assembly. One method includes optically inspecting a solder bond bonding a thermal pad of an exposed pad IC package to a printed circuit board. Another method includes wave soldering an exposed pad of an IC package to a printed circuit board.