Abstract: Disclosed is a wheeled vehicle. The wheeled vehicle includes various features for operation by a rider, such as a throttle actuation assembly and various components for operation and manipulation of the vehicle.

Abstract: The present invention relates to certain anti-M(H)DM2/4 antibodies or antigen-binding fragments thereof, pharmaceutical compositions comprising anti-M(H)DM2/4 antibodies or antigen-binding fragments thereof, antibody-drug conjugates comprising anti-M(H)DM2/4 antibodies or antigen-binding fragments thereof bound to a cytotoxic drug, and the use of such antibodies, fragments, compositions and conjugates for treating cancer and/or for preventing metastases. In particular, described herein are certain antibodies or antigen-binding fragments thereof that specifically bind to extracellularly accessible epitopes of M(H)DM2/4 and inhibit tumor growth in vivo, pharmaceutical compositions comprising such antibodies or fragments, antibody-drug conjugates comprising such antibodies or fragments, and the use of such antibodies, fragments, compositions and conjugates for treating cancer or for preventing metastasis.

Abstract: A hydraulic system for controlling an implement on a work machine may include a hydraulic reservoir, a hydraulic pump in fluid communication with the reservoir, a central valve in fluid communication with the pump and configured for controlling the implement, a load sense pressure relief system, and a controller. The controller may be configured for controlling the central valve and the load sense pressure relief system and selecting between operating the hydraulic system at a first pressure and a second pressure based on a factor relating to implement position.

Abstract: A transparent device for use in optical applications, and methods for using and manufacturing the device are disclosed. The device generally requires several layers, including (i) a first layer comprising a transparent conductive oxide (such as indium tin oxide (ITO)), (ii) a second layer comprising a transparent semiconductor (e.g., a pn-heterojunction or a pn-homojunction), the second layer having a surface facing the first layer, (iii) a third layer comprising a liquid crystal (such as E7), the third layer having a surface facing the second layer, and (iv) a fourth layer comprising either a second transparent conductive oxide or a second transparent semiconductor, the fourth layer having a surface facing the third layer. When light illuminates a surface of the transparent metal oxide pn-heterojunction or transparent metal oxide pn-homojunction, it induces photoconductivity, modifying the surface charges.

Abstract: The present invention relates to certain anti-M(H)DM2/4 antibodies or antigen-binding fragments thereof, pharmaceutical compositions comprising anti-M(H)DM2/4 antibodies or antigen-binding fragments thereof, antibody-drug conjugates comprising anti-M(H)DM2/4 antibodies or antigen-binding fragments thereof bound to a cytotoxic drug, and the use of such antibodies, fragments, compositions and conjugates for treating cancer and/or for preventing metastases. In particular, described herein are certain antibodies or antigen-binding fragments thereof that specifically bind to extracellularly accessible epitopes of M(H)DM2/4 and inhibit tumor growth in vivo, pharmaceutical compositions comprising such antibodies or fragments, antibody-drug conjugates comprising such antibodies or fragments, and the use of such antibodies, fragments, compositions and conjugates for treating cancer or for preventing metastasis.

Abstract: An adjustable sub-base mounting assembly for installing a pump onto a concrete base includes a track assembly having at least one upper track member, wherein one or more cradles supporting the pump are mounted to a portion of the upper track member. The track assembly includes at least one lower track member disposed in sliding engagement with the upper track member(s) to allow the pump to be movable via the track assembly. A sub-base assembly has a sub-base and at least one track support member, the lower track member(s) secured to the track support member. The adjustable sub-base mounting assembly includes one or more one jacking bolts to adjustably secure the track support member(s) to the sub-base, allowing for adjustable positioning of the track support member(s) relative to the sub-base, thereby permitting precise alignment of the rotating unit with the volute of the pump.

Abstract: A stage tool used in a wellbore has a housing consisting of two sub-housings that couple together. A first sleeve is movably disposed in the housing bore and is held closed with a temporary connection relative to a side port of the housing. The first sleeve has a first seat of millable material. A second sleeve is also movably disposed in the housing bore and is held opened with a temporary connection relative to the side port. The second sleeve has a second seat of millable material. An opening plug is landed on the first seat so pressure can break the connection and shift the first sleeve open relative to the side port. After pumping cement out of the tool, a closing plug is pumped to the second seat so pressure can break the connection and shift the second sleeve closed relative to the side port. The first sleeve includes a bypass that allows for fluid to pass beyond the seated plug.

Abstract: The present invention relates to a herbicidal composition comprising specific pigment synthesis inhibitors selected from beflubutamide, flurtamone and clomazone. The invention also relates to methods and uses for controlling undesirable vegetation, in particular in crops.

Abstract: A transparent device for use in optical applications, and methods for using and manufacturing the device are disclosed. The device generally requires several layers, including (i) a first layer comprising a transparent conductive oxide (such as indium tin oxide (ITO)), (ii) a second layer comprising a transparent semiconductor (e.g., a pn-heterojunction or a pn-homojunction), the second layer having a surface facing the first layer, (iii) a third layer comprising a liquid crystal (such as E7), the third layer having a surface facing the second layer, and (iv) a fourth layer comprising either a second transparent conductive oxide or a second transparent semiconductor, the fourth layer having a surface facing the third layer. When light illuminates a surface of the transparent metal oxide pn-heterojunction or transparent metal oxide pn-homojunction, it induces photoconductivity, modifying the surface charges.

Abstract: The present invention relates to a herbicidal composition which comprises: a) at least one herbicide A selected from glyphosate, glufosinate and their salts, and b) a herbicide B which is 3-[5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)pyrazol-4-ylmethylsulfonyl]-4,5-dihydro-5,5-dimethyl-1,2-oxazole [common name: pyroxasulfone]. The present invention relates in particular to a herbicidal composition comprising: a) at least one herbicide A selected from glyphosate, glufosinate and their salts, b) a herbicide B which is 3-[5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)pyrazol-4-ylmethylsulfonyl]-4,5-dihydro-5,5-dimethyl-1,2-oxazole [common name: pyroxasulfone], and c) at least one further herbicide C, which is selected from the herbicide groups C.1 to C.8: C.1 herbicides of the group of acetolactate synthase inhibitors (ALS inhibitors), C.2 herbicides of the group of protoporphyrinogen oxidase inhibitors (PPO inhibitors), C.3 herbicides of the group of auxines, C.

Abstract: The present disclosure provides an aerogel composition which is durable and easy to handle, which has favorable performance in aqueous environments, and which also has favorable combustion and self-heating properties. Also provided is a method of preparing an aerogel composition which is durable and easy to handle, which has favorable performance in aqueous environments, and which has favorable combustion and self-heating properties. Further provided is a method of improving the hydrophobicity, the liquid water uptake, the heat of combustion, or the onset of thermal decomposition temperature of an aerogel composition.

Abstract: An earth-boring tool may include a tool body and a coupling region configured to couple the earth-boring tool to an adjacent portion of a drill string. The earth-boring tool may also include one or more sensors disposed on the tool body. The earth-boring tool may further include a connector disposed in the coupling region electrically connected to the one or more sensors. The connector may be configured to enable a removable connection from an external device to the one or more sensors.

Abstract: Aerogel materials, aerogel composites and the like may be improved by enhancing their smoke suppression, combustion reduction properties. It is additionally useful to provide aerogel based composites compatible with environments conducive to combustion. Such aerogel materials and methods of manufacturing the same are described.

Abstract: The present invention relates to uracilpyridines of formula (I) or their agriculturally acceptable salts or derivatives, wherein the variables are defined according to the description, processes and intermediates for preparing the uracilpyryidines of the formula (I), compositions comprising them and their use as herbicides, i.e. for controlling harmful plants, and also a method for controlling unwanted vegetation which comprises allowing a herbicidal effective amount of at least one urycilpyridine of the formula (I) to act on plants, their seed and/or their habitat.

Abstract: A downhole sensor apparatus may include a structure securing a circuit board. The structure may be configured to be inserted into a recess in a tool on a drill string. The downhole sensor apparatus may include one or more sensors coupled to the circuit board and a cap over the structure. The downhole sensor apparatus may further include a data port electrically coupled to the circuit board and configured to transmit data from the sensors to an external device. The downhole sensor apparatus may include a threaded element configured to thread into complementary threads in the recess in the tool. The downhole sensor apparatus may be configured to operate in an idle condition. The downhole sensor apparatus may compare readings from at least two sensors to threshold downhole conditions and begin normal operation when the readings from the at least two sensors meet or exceed the threshold downhole conditions.

Abstract: A downhole sensor system may include at least two accelerometers having at least two axes of measurement. The at least two accelerometers may include a first accelerometer in a first position and a second accelerometer in a second position. A first axis of the second accelerometer may be substantially coaxial with a first axis of the first accelerometer and a second axis of the second accelerometer may be parallel to and offset from a second corresponding axis of the first accelerometer. The downhole sensor system may further include at least one processor, and at least one non-transitory computer-readable storage medium storing instructions thereon that when executed by the at least one processor may cause the processor to measure a first acceleration from the first accelerometer and measure a second acceleration from the second accelerometer.

Abstract: A high speed tabletop and industrial printer is disclosed with integrated high speed RFID encoding and verification at the same time. The industrial printer simultaneously prints on and electronically encodes/verifies RFID labels, tags, and/or stickers attached to a continuous web. The industrial printer comprises a lighted sensor array for indexing the printing to the RFID tags; and a cutter powered from the industrial printer for cutting the web that the RFID tags are disposed on. The industrial printer comprises two RFID reader/writers that are individually controlled. Specifically, one of the RFID reader/writers comprises the ability to electronically encode the RFID tags while the web is moving; and the second RFID reader/writer uses an additional RFID module and antenna on the printer for verifying the data encoded to the RFID tags.

Abstract: The present invention relates to a herbicidal composition comprising specific inhibitors of protoporphyrinogen oxidase (PPO inhibitors) selected from flumioxazin and sulfentrazone. The invention also relates to methods and uses for controlling undesirable vegetation, in particular in crops.

Abstract: The present invention relates to a herbicidal composition comprising imazamox, any of its individual isomers or agriculturally acceptable salts, esters or amides thereof. The invention also relates to methods and uses for controlling undesirable vegetation, in particular in crops.

Abstract: The present invention describes various methods for manufacturing gel composite sheets using segmented fiber or foam reinforcements and gel precursors. Additionally, rigid panels manufactured from the resulting gel composites are also described. The gel composites are relatively flexible enough to be wound and when unwound, can be stretched flat and made into rigid panels using adhesives.