Abstract: A vehicle, Lidar system and method of detecting an object is disclosed. The Lidar system includes a photonic chip, and a laser integrated into the photonic chip. The laser has a front facet located at a first aperture of the photonic chip to direct a transmitted light beam into free space. A reflected light beam that is a reflection of the transmitted light beam is received at the photonic chip and a parameter of the object is determined from a comparison of the transmitted light beam and the reflected light beam. A navigation system operates the vehicle with respect to the object based on a parameter of the object.

Abstract: A vehicle, Lidar system and method of detecting an object is disclosed. The Lidar system includes a photonic chip having an aperture, one or more photodetectors and a circulator. A transmitted light beam generated within the photonic chip exits the photonic chip via the aperture and a reflected light beam enters the photonic chip via the aperture, the reflected light beam being a reflection of the transmitted light beam from the object. The one or more photodetectors measure the parameter of the object from at least the reflected light beam. The circulator integrated into the photonic chip directs the transmitted light beam toward the aperture and directs the reflected light beam from the aperture to the one or more photodetectors. A navigation system navigates the vehicle with respect to the object based on the parameter of the object.

Abstract: Devices and methods for treatment of a patient's vasculature are described. Embodiments may include a permeable implant having a radially constrained state configured for delivery within a catheter lumen, an expanded state, and a plurality of elongate filaments that are woven together. The permeable implant may include a stiffer proximal portion that is configured to sit at the neck of an aneurysm. The stiffer proximal portion may include coils, stiffening elements, or reinforcement elements disposed about or associated with the filaments or woven together with the filaments.

Abstract: A method of bonding a double-ended cable to a multi-tier substrate (such as a multi-tier printed circuit board) includes picking up the double-ended cable, and imaging alignment markers on a first head of the double-ended cable, a second substrate of the multi-tier substrate, a second head of the double-ended cable, and a first substrate of the multi-tier substrate. The method also includes aligning the alignment marker on the first head of the cable to the alignment marker on the second substrate of the multi-tier substrate, coupling the first head of the cable to the second substrate, and releasing the first head of the cable. The method further includes aligning the alignment marker on the second head of the cable to the alignment marker on the first substrate of the multi-tier substrate, coupling the second head of the cable to the first substrate, and releasing the second head of the cable.

Abstract: Devices and methods for treatment of a patient's vasculature are described. Embodiments may include a permeable implant having a radially constrained state configured for delivery within a catheter lumen, an expanded state, and a plurality of elongate filaments that are woven together. The implant may include first and second permeable shells. The first permeable shell having a proximal end with a concave or recessed section and a second permeable shell having a convex section that mates with the concave or recessed section. The implant also includes a flexible, articulating joint between the first and second permeable shells.

Abstract: Devices and methods for treatment of a patient's vasculature are described. Embodiments may include a permeable implant such as a permeable shell or mesh having a radially constrained state configured for delivery within a catheter lumen, an expanded state, and a plurality of elongate filaments that are woven together. The permeable implant may include a stiffer proximal portion that is configured to sit at the neck of an aneurysm. The stiffer proximal portion may include additional mesh layers on either the inside or the outside of a first permeable shell. The distal portion of the device may be softer and deformable.

Abstract: Provided is a voice assistance system with proactive routines that couples a remote server and respective user voice interactive devices to deliver a complete experience to the end user of the device. The voice assistance system can also provide a platform to connect remote users to customize commands (e.g., proactive or reactive) to improve day-to-day operation across groups of devices and/or users. For example, routines can be built for an organization and made available to voice interactive devices distributed by or on behalf of the organization. Administrators can select features for the device and pre-configure voice assistance devices with groups of pre-selected routines to deliver a device that is ready to go out of the box. Updates to a device or routines can be based on such groups. Additionally, primary routine instances can be linked to groups where changes to the primary instance are propagated to any linked users.

Abstract: Provided is a voice assistance system with proactive routines that couples a remote server and respective user voice interactive devices to deliver a complete experience to the end user of the device. The user devices can be managed by groups and/or associated entities who manage voice services for their users. For example, the entities can provide pre-configured voice routines that perform actions on behalf of their users. The voice assistance system can also allow users to customize these routines to improve day to day operation. In addition, external services and/or providers can be linked to the system and allowed to define routines that have external system dependencies. Avoiding and managing conflicts in this environment becomes quite challenging. Some approaches use execution queues and priority, others invoke time slices and limitations on assignment of routines to time slices to resolve these issues, among other examples.

Abstract: Devices and methods for treatment of a patient's vasculature are described. Embodiments may include a permeable implant such as a permeable shell or mesh having a radially constrained state configured for delivery within a catheter lumen, an expanded state, and a plurality of elongate filaments that are woven together. The permeable implant may include a stiffer proximal portion that is configured to sit at the neck of an aneurysm. The stiffer proximal portion may include additional mesh layers on either the inside or the outside of a first permeable shell. The distal portion of the device may be softer and deformable.

Abstract: A micro-optical bench includes a substrate having a multi-layer trench and a micro-lens aligned by and mounted to the substrate in the multi-layer trench.

Abstract: Devices and methods for treatment of a patient's vasculature are described. Embodiments may include a permeable implant having a radially constrained state configured for delivery within a catheter lumen, an expanded state, and a plurality of elongate filaments that are woven together. The implant may include first and second permeable shells. The first permeable shell having a proximal end with a concave or recessed section and a second permeable shell having a convex section that mates with the concave or recessed section. The implant also includes a flexible, articulating joint between the first and second permeable shells.

Abstract: Described herein is an aircraft. The aircraft includes a peripheral assembly, such as a sensor probe. The aircraft further includes a release assembly connecting the peripheral assembly to a portion of the aircraft. The release assembly is configured to separate the peripheral assembly and the portion upon receipt of a threshold force. The release assembly may be configured to allow for the quick release, such as via a snap-fit connection, between the peripheral assembly and the portion of the aircraft.

Abstract: Described herein are durable coatings, i.e. for medical devices, and methods of forming the coatings.

Abstract: The present invention relates to pyrrolidine sulfonamide analogs, pharmaceutical compositions containing them and their use as TRPV4 antagonists.

Abstract: A chip-scale coherent lidar system includes a master oscillator integrated on a chip to simultaneously provide a signal for transmission and a local oscillator (LO) signal. The system also includes a beam steering device to direct an output signal obtained from the signal for transmission out of the system, and a combiner on the chip to combine the LO signal and a return signal resulting from a reflection of the output signal by a target. One or more photodetectors obtain a result of interference between the LO signal and the return signal to determine information about the target.

Abstract: An acoustic detection system of an aircraft receives a first signal, where the first signal is a multichannel audio signal. The multichannel audio signal is determined to be associated with at least one intruding aircraft based on the multichannel audio signal. An avoidance maneuver is commanded for the aircraft based on a track of the intruding aircraft generated based on the multichannel audio signal and a second signal providing additional information about the intruding aircraft.

Abstract: Devices and methods for treatment of a patient's vasculature are described. Embodiments may include a permeable implant connected to an expandable stent through a plurality of wires. The permeable shell is configured for placement in an aneurysm and the expandable stent is configured for placement in a parent vessel proximal, near, or adjacent the aneurysm.

Abstract: Devices and methods for treatment of a patient's vasculature are described. Embodiments may include a device that includes a plurality of permeable shells connected by a plurality of coils, each coil connecting at least one pair of permeable shells. The plurality of coils may include an inert hydrogel core that absorbs water.

Abstract: Devices and methods for treatment of a patient's vasculature are described. The device includes a self-expanding resilient permeable shell having a radially constrained state and an expanded state with a globular, axially shortened configuration. The permeable shell may be a single layer of braided elongate filaments having first and second ends that are secured at the proximal end of the permeable shell. The devices may also include permeable shells made of woven braided mesh having a variable mesh density, i.e., the average size of pores in one region are a different than the average size of pores in another region. Methods of using the device to treat a cerebral aneurysm are also described. Methods of forming a tubular braid are also described. Methods of forming a tubular braid with variable braid densities are described. Methods of forming a tubular braid using a castellated mandrel are also described.

Abstract: A chip-scale LIDAR (light detection and ranging) system, optical package and LIDAR platform. The system includes a photonic chip, a laser associated with the photonic chip, an optical circulator, and a MEMS scanner. The laser, the optical circulator and the MEMS scanner are collinear. The photonic chip includes an edge coupler. The optical package includes a housing having an aperture, and a platform within the housing. The platform includes the laser, an optical circulator, and MEMS scanner.