Abstract: A micro-optical bench includes a substrate having a multi-layer trench and a micro-lens aligned by and mounted to the substrate in the multi-layer trench.

Abstract: Devices and methods for treatment of a patient's vasculature are described. Embodiments may include a permeable implant having a radially constrained state configured for delivery within a catheter lumen, an expanded state, and a plurality of elongate filaments that are woven together. The implant may include first and second permeable shells. The first permeable shell having a proximal end with a concave or recessed section and a second permeable shell having a convex section that mates with the concave or recessed section. The implant also includes a flexible, articulating joint between the first and second permeable shells.

Abstract: Described herein is an aircraft. The aircraft includes a peripheral assembly, such as a sensor probe. The aircraft further includes a release assembly connecting the peripheral assembly to a portion of the aircraft. The release assembly is configured to separate the peripheral assembly and the portion upon receipt of a threshold force. The release assembly may be configured to allow for the quick release, such as via a snap-fit connection, between the peripheral assembly and the portion of the aircraft.

Abstract: Described herein are durable coatings, i.e. for medical devices, and methods of forming the coatings.

Abstract: The present invention relates to pyrrolidine sulfonamide analogs, pharmaceutical compositions containing them and their use as TRPV4 antagonists.

Abstract: A chip-scale coherent lidar system includes a master oscillator integrated on a chip to simultaneously provide a signal for transmission and a local oscillator (LO) signal. The system also includes a beam steering device to direct an output signal obtained from the signal for transmission out of the system, and a combiner on the chip to combine the LO signal and a return signal resulting from a reflection of the output signal by a target. One or more photodetectors obtain a result of interference between the LO signal and the return signal to determine information about the target.

Abstract: An acoustic detection system of an aircraft receives a first signal, where the first signal is a multichannel audio signal. The multichannel audio signal is determined to be associated with at least one intruding aircraft based on the multichannel audio signal. An avoidance maneuver is commanded for the aircraft based on a track of the intruding aircraft generated based on the multichannel audio signal and a second signal providing additional information about the intruding aircraft.

Abstract: Devices and methods for treatment of a patient's vasculature are described. Embodiments may include a permeable implant connected to an expandable stent through a plurality of wires. The permeable shell is configured for placement in an aneurysm and the expandable stent is configured for placement in a parent vessel proximal, near, or adjacent the aneurysm.

Abstract: Devices and methods for treatment of a patient's vasculature are described. Embodiments may include a device that includes a plurality of permeable shells connected by a plurality of coils, each coil connecting at least one pair of permeable shells. The plurality of coils may include an inert hydrogel core that absorbs water.

Abstract: Devices and methods for treatment of a patient's vasculature are described. The device includes a self-expanding resilient permeable shell having a radially constrained state and an expanded state with a globular, axially shortened configuration. The permeable shell may be a single layer of braided elongate filaments having first and second ends that are secured at the proximal end of the permeable shell. The devices may also include permeable shells made of woven braided mesh having a variable mesh density, i.e., the average size of pores in one region are a different than the average size of pores in another region. Methods of using the device to treat a cerebral aneurysm are also described. Methods of forming a tubular braid are also described. Methods of forming a tubular braid with variable braid densities are described. Methods of forming a tubular braid using a castellated mandrel are also described.

Abstract: A chip-scale LIDAR (light detection and ranging) system, optical package and LIDAR platform. The system includes a photonic chip, a laser associated with the photonic chip, an optical circulator, and a MEMS scanner. The laser, the optical circulator and the MEMS scanner are collinear. The photonic chip includes an edge coupler. The optical package includes a housing having an aperture, and a platform within the housing. The platform includes the laser, an optical circulator, and MEMS scanner.

Abstract: An occlusion device including a tubular braided member having a first end and a second end and extending along a longitudinal axis, the tubular braided member having a repeating pattern of larger diameter portions and smaller diameter portions arrayed along the longitudinal axis, and at least one metallic coil member extending coaxially along at least a portion of the braided member, the at least one metallic coil member having an outer diameter and an inner diameter, wherein the smaller diameter portions of the tubular braided member have an outer diameter and an inner diameter, and wherein at least one of the outer diameter and inner diameter of the tubular braided member is configured to closely match a directly opposing diameter of the metallic coil member.

Abstract: A photonic edge coupler includes a slab waveguide and a ridge waveguide. The ridge waveguide includes a silicon wire waveguide, which includes a tapered portion. A first end of the slab waveguide is joined to the ridge waveguide at a junction, and a second end of the slab waveguide forms a first facet. The ridge waveguide defines a longitudinal axis that is associated with a direction of a light signal therein. The first facet is angled at less than 90 degrees relative to the longitudinal axis associated with the direction of the light signal therein. The first facet is disposed opposite to a laser facet associated with a laser waveguide. The longitudinal axis of the ridge waveguide defines a first center point, and the laser facet and the associated laser waveguide define a second center point. The second center point is laterally offset from the first center point.

Abstract: A lidar system includes a photonic chip including a light source and a transmit beam coupler to provide an output signal for transmission. The output signal is a frequency modulated continuous wave (FMCW) signal. A transmit beam steering device transmits the output signal from the transmit beam coupler of the photonic chip. A receive beam steering device obtains a reflection of the output signal by a target and provides the reflection as a received signal to a receive beam coupler of the photonic chip. The photonic chip, the transmit beam steering device, and the receive beam steering device are heterogeneously integrated into an optical engine.

Abstract: An inflatable head restraint system for a parachute assembly may comprise an inflatable volume configured to inflate in response to a deployment of the parachute assembly. The inflatable volume may be located between a left shoulder riser and a right shoulder riser of the parachute assembly. A conduit may be fluidly coupled to the inflatable volume.

Abstract: A blade positioning system and method are provided to dynamically measure blade position during flight of a rotorcraft. In the context of a method, a blade of the rotorcraft is repeatedly illuminated by a light source during flight of the rotorcraft while the blade is rotating. The method also includes detecting radiation scattered from the blade in response to illumination of the blade. The method further includes determining at least one of a blade pitch angle, a blade flap angle, a blade leading position or a blade lagging position based upon the radiation that is scattered from the blade and detected.

Abstract: A parachute assembly for decelerating an occupant of an ejection seat may comprise a left shoulder riser configured to be located over a left shoulder of the occupant upon deployment of the parachute assembly. A right shoulder riser may be configured to be located over a right shoulder of the occupant upon deployment of the parachute assembly. A head restraint, configured to be behind a head of the occupant upon deployment of the parachute assembly, may be located between the left and right shoulder risers.

Abstract: A parachute assembly for an ejection seat may comprise a canopy and a first suspension line coupled to the canopy. A first riser may be coupled to the first suspension line. A seat cushion may be coupled to the first riser. The seat cushion may be configured detach from the ejection seat and restrict rearward translation of a head of an occupant of the ejection seat upon deployment of the parachute assembly.

Abstract: A system for delivering an implant device to a vascular site in a patient a delivery pusher apparatus, an implant device detachably connected to the delivery pusher apparatus by a tether having a distal end connected to a proximal end of the implant device, wherein the tether is substantially non-tensioned when connecting the implant device to the delivery pusher, and an electrical heating element configured coaxially around at least a portion of the tether, wherein heat generated by the heating element severs the tether at a point near the proximal end of the implant device.

Abstract: A LIDAR system, LIDAR chip and method of manufacturing a LIDAR chip. The LIDAR system includes a photonic chip configured to transmit a transmitted light beam and to receive a reflected light beam, a scanner for directing the transmitted light beam towards a direction in space and receiving the reflected light beam from the selected direction, and a fiber-based optical coupler. The photonic chip and the scanner are placed on a semiconductor integrated platform (SIP). The fiber-based optical coupler is placed on top of the photonic chip to optically couple to the photonic chip for directing the a transmitted light beam from the photonic chip to the scanner and for directing a reflected light beam from the scanner to the photonic chip.