Abstract: A parachute assembly for decelerating an occupant of an ejection seat may comprise a left shoulder riser configured to be located over a left shoulder of the occupant upon deployment of the parachute assembly. A right shoulder riser may be configured to be located over a right shoulder of the occupant upon deployment of the parachute assembly. A head restraint, configured to be behind a head of the occupant upon deployment of the parachute assembly, may be located between the left and right shoulder risers.

Abstract: An inflatable head restraint system for a parachute assembly may comprise an inflatable volume configured to inflate in response to a deployment of the parachute assembly. The inflatable volume may be located between a left shoulder riser and a right shoulder riser of the parachute assembly. A conduit may be fluidly coupled to the inflatable volume.

Abstract: A system for translating a head restraint of a parachute assembly away from a head of an occupant supported by the parachute assembly may comprise a chord coupled to the head restraint and at least one of a control line configured to manipulate a canopy of the parachute assembly or a handle coupled to the control line.

Abstract: A parachute assembly for an ejection seat may comprise a canopy and a first suspension line coupled to the canopy. A first riser may be coupled to the first suspension line. A seat cushion may be coupled to the first riser. The seat cushion may be configured detach from the ejection seat and restrict rearward translation of a head of an occupant of the ejection seat upon deployment of the parachute assembly.

Abstract: A Lidar system, photonic chip and method of detecting an object is disclosed. The Lidar system includes the photonic chip. The photonic chip includes a laser and a local oscillator waveguide. The laser is integrated into the photonic chip and generates a leakage energy at a back facet of the laser for use as a local oscillator beam for the photonic chip. The local oscillator waveguide receives the leakage energy as the local oscillator beam. The laser further generates a transmitted light beam through a front facet of the photonic chip, combining the leakage energy with a reflection of the transmitted light beam form an object, and detects a combination of the reflected light beam and the leakage energy to determine a parameter of the object.

Abstract: A vehicle, Lidar system and method of detecting an object is disclosed. The Lidar system includes a photonic chip, and a laser integrated into the photonic chip. The laser has a front facet located at a first aperture of the photonic chip to direct a transmitted light beam into free space. A reflected light beam that is a reflection of the transmitted light beam is received at the photonic chip and a parameter of the object is determined from a comparison of the transmitted light beam and the reflected light beam. A navigation system operates the vehicle with respect to the object based on a parameter of the object.

Abstract: A vehicle, Lidar system and method of detecting an object is disclosed. The Lidar system includes a photonic chip having an aperture, one or more photodetectors and a circulator. A transmitted light beam generated within the photonic chip exits the photonic chip via the aperture and a reflected light beam enters the photonic chip via the aperture, the reflected light beam being a reflection of the transmitted light beam from the object. The one or more photodetectors measure the parameter of the object from at least the reflected light beam. The circulator integrated into the photonic chip directs the transmitted light beam toward the aperture and directs the reflected light beam from the aperture to the one or more photodetectors. A navigation system navigates the vehicle with respect to the object based on the parameter of the object.

Abstract: The present invention relates to pyrrolidine sulfonamide analogs, pharmaceutical compositions containing them and their use as TRPV4 antagonists.

Abstract: A chip-scale LIDAR (light detection and ranging) system, optical package and LIDAR platform. The system includes a photonic chip, a laser associated with the photonic chip, an optical circulator, and a MEMS scanner. The laser, the optical circulator and the MEMS scanner are collinear. The photonic chip includes an edge coupler. The optical package includes a housing having an aperture, and a platform within the housing. The platform includes the laser, an optical circulator, and MEMS scanner.

Abstract: Mechanisms are provided for caching patient information in a variable list and using the variable list to evaluate patient rules. The mechanisms generate a patient registry comprising a plurality of patient registry records, each patient registry record being associated with a corresponding patient and comprising personal and medical information about the corresponding patient. The mechanisms compile at least one variable list for an input variable of one or more clinical rules. The variable list comprises a plurality of instances of personal and medical information from the plurality of sources that are associated with the variable. The mechanisms also process at least one clinical rule in the one or more clinical rules that references the variable as a criteria for evaluating the at least one clinical rule, based on the variable list associated with the variable to determine if the criteria is satisfied by one or more instances.

Abstract: Mechanisms are provided for communicating with a patient. The mechanisms generate a patient registry comprising a plurality of patient registry records, each patient registry record being associated with a corresponding patient and comprising personal and medical information about the corresponding patient. The mechanisms collect, for each patient registry record, first data regarding treatment of the corresponding patient and second data regarding communications made with the corresponding patient. The mechanisms determine, based on analysis of the first data and second data associated with each of the patient registry records, a mode of communication that is most likely to result in a successful treatment of patients. The mechanisms initiate a communication with a patient of interest using the determined mode of communication based on the results of the determination.

Abstract: A transistor having an emitter, a base, and a collector, the transistor includes a substrate, a collector contact, a metallic sub-collector coupled to the collector contact, and the metallic sub-collector electrically and thermally coupled to the collector, and an adhesive layer between the substrate and the metallic sub-collector, the adhesive layer bonded to the substrate and in direct contact with the substrate and bonded to the metallic sub-collector and in direct contact with the metallic sub-collector, wherein the adhesive layer comprises an electrically conductive material.

Abstract: Catalytic systems and methods for treating process streams are disclosed. Catalytic wet oxidation and hydrolysis techniques may be used to treat one or more undesirable constituents. Methane may be produced in connection with at least some embodiments.

Abstract: Systems and methods for providing an electrical interface to a body are provided. In one embodiment, an implantable module is disclosed, comprising: an implantable electrode array, implantable within a body and capable of providing a plurality of communication channels for communicating electrical signals detected in a body; an amplifier circuit for processing electrical signals received from the electrode array; a wireless transceiver for sending and receiving telemetry data between the amplifier circuit and a wireless receiver located outside of the body; and a sealed enclosure that houses the amplifier circuit and the wireless transmitter and is biocompatible with surrounding tissue, the enclosure having a window that is transparent to a wireless medium used by the wireless transceiver.

Abstract: A connection is established between a pin connector and a box connector defined on a pair of tubular members such as casing segments in the field of oil and gas recovery. The pin connector and box connector include features for the protection of metallic-sealing surfaces during assembly, disassembly, transport and handling of the tubular members. The pin connector includes a stabbing flank with an inwardly tapered annular flank surface thereon, and an alignment protrusion extending outward with respect to the pin-side metallic sealing surface in a direction normal to a cone angle defined by the inwardly tapered annular flank surface. The alignment protrusion engages internal surfaces of the box connector to concentrically align the pin connector with the box connector, and thereby protects the metallic sealing surfaces from damage that might otherwise result from collisions between the pin connector and the box connector.

Abstract: The present invention provides novel T type calcium channel inhibitors of formula (I), the use thereof in the treatment of a disease or condition in a mammal associated with influx of extracellular calcium via T type calcium channels, wherein R1 is C1-C4 alkyl, hydroxy, or C1-C4 alkoxy; Z is NH, NCH3, O, S, or CH2; Y is NH, O, or CH2 with the proviso that Y and Z are not the same; R2 is H, halo, NH2, C1-C4 alkyl, hydroxy, or C1-C4 alkoxy; m and n are independently selected from integers ranging from 1-5 with the proviso that m+n=an integer ranging from 2-9; and R3 is H, halo, NH2, C1-C4 alkyl, hydroxy, or C1-C4 alkoxy.

Abstract: A method of manufacturing an optical waveguide includes: aligning a silicon on insulator wafer and a target substrate, the target substrate including a benzocyclobutene layer; bonding a silicon layer of the silicon on insulator wafer with the benzocyclobutene layer of the target substrate by using heat and pressure; and removing the silicon on insulator wafer such that the silicon layer remains on the benzocyclobutene layer.

Abstract: Methods and devices for treating a cerebral aneurysm are described. The device may include a self-expanding resilient permeable shell made from elongate resilient filaments. At least some of the filaments have a distal region that extends beyond the distal end of the permeable shell and form an extension having a generally circular shape when expanded. The permeable shell has a radially constrained elongated state configured for delivery within a microcatheter and has an expanded state with a globular, axially shortened configuration. The permeable shell has a plurality of openings formed between the braided filaments. The distal regions of the plurality of filaments that form the extension may be braided, partially braided, or unraveled. Once deployed within the cerebral aneurysm, the extension is positioned near a dome of the cerebral aneurysm.

Abstract: The present invention relates to pyrrolidine sulfonamide analogs, pharmaceutical compositions containing them and their use as TRPV4 antagonists.

Abstract: Devices and methods for treatment of a patient's vasculature are described. Embodiments may include a resilient self-expanding permeable implant having a radially constrained elongated state configured for delivery within a catheter lumen and an expanded state with a longitudinally shortened configuration, and a plurality of elongate filaments which are woven together. Each of the plurality of elongate filaments may have a diameter between about 0.0005 and about 0.005 inches. The implant includes at least some filaments consisting of nitinol and at least some composite filaments that are drawn filled tube wires comprising an external nitinol tube and a highly radiopaque material concentrically disposed within the external tube. The implant has at least about 40% composite filaments relative to a total number of filaments, and wherein a total number of filaments is about 10 to about 300.