Abstract: This application relates generally to the production of polypeptides having specific antigen-binding properties of Fv domains, for example, insertable variable fragments of antibodies, and modified ?1-?2 domains of NKG2D ligands.

Abstract: In one embodiment, a processing device receives a first digital fingerprint of a media item along with a first content management rule. The processing device separately receives a second digital fingerprint of the media item along with a second content management rule. The processing device determines that the received digital fingerprints are for the same media item based upon a match between the first digital fingerprint and the second digital fingerprint. The processing device determines that all rights to the media item have been accounted for, and then determines a set of actions to be performed for hosted media items comprising the media item based at least in part upon the first content management rule and the second content management rule. Processing logic may also perform a conflict resolution process for conflicting rights claims to the media item.

Abstract: A processing system for processing a flexographic printing plate can include a processing path for processing the flexographic printing plate. A hollow tube can be positioned to be extended across the processing path. A pressurized processing liquid supply system is provided. A plurality of pressure-compensating emitters are coupled to the hollow tube Each pressure-compensating emitter can include a casing having a fluidic flow path that is fluidly coupled with the hollow tube and having an outlet. Also, each emitter can include a resilient planar member in the casing and positioned to form at least one resilient surface of the fluidic flow path. Each pressure-compensating emitter is configured to control flow rate of the pressurized processing liquid to produce processing liquid drips from the outlet. The resilient planar member can be positioned to provide a variable outlet cross-sectional profile to the outlet in response to pressure inside the casing.

Abstract: Disclosed herein are methods for treating or prophylactically treating age-related cognitive decline associated with dementia by administering recombinant viral vectors designed to deliver TERT and/or KL (Klotho) genes to the patient. The TERT and/or KL genes are packaged within one or more AAV viral vectors and administered to the CNS of the patient via intranasal and/or intrathecal injection. The therapy can provide improvements in cognitive function as evidenced by improved Folstein/MMSE scores over time.

Abstract: An expandable cargo bed system for a vehicle includes a front shell having a front shell first sidewall. The front shell first sidewall includes at least one cargo bed access passage extending between a first side of the front shell first sidewall and a second side of the front shell first sidewall opposite the first side. A rear shell is operably coupled to the front shell so as to be movable with respect to the front shell between a retracted position and an extended position so as to vary a length of the cargo bed. The rear shell has a rear shell first sidewall. The rear shell first sidewall is structured to cover the at least one cargo bed access passage when the rear shell is in the retracted position. The rear shell first sidewall is also structured so that the at least one cargo bed access passage is exposed when the rear shell is in the extended position.

Abstract: A bone fusion device includes: a shaft including a porous section and a threaded proximal section configured for facilitating a compression.

Abstract: A system has fiber amplifiers that amplify a seed signal into a high power signal. Control circuity drives the fiber amplifiers. An auxiliary broad-linewidth signal can be selectively introduced to mitigate the onset of Stimulated Brillouin Scattering (SBS) when the primary input seed source does not meet the requirements of power and/or linewidth. To determine whether to mitigate SBS, an input photodiode can detect the seed signal, and the control circuity can detect an operational parameter associated with a detected signal indicative of an onset of SBS on the optical path. In response to the detection, the control circuitry introduces an auxiliary broad-linewidth signal from a broad-linewidth source, which can mitigate the onset of SBS on the optical path.

Abstract: A wrist joint, such as for a surgical instrument, may include a first disc, a second disc adjacent the first disc, a drive tendon connecting the first disc and the second disc. The first disc and the second disc may include respective opposing gear features that intermesh with one another. The first disc and the second disc may further include opposing load bearing surfaces. In response to tensioning the drive tendon, the first and second discs rotate relative to each other. The first and second discs may have a maximum rotational range of motion greater than about +/?45 degrees relative to each other.

Abstract: A food locker includes a housing, a food support member, a first door, a second door, and a lock. The housing includes a front wall a front wall, a rear wall, and a chamber. The front wall includes a first opening in communication with the chamber. The rear wall includes a second opening in communication with the chamber. The food support member is disposed within the chamber. The first door is supported by the housing and is movable between a closed position and an open position. The food support member is accessible through the first opening when the first door is in the open position. The second door is supported by the housing and is movable between a closed position and an open position. The food support member is accessible through the second opening when the second door is in the open position. The lock is operatively coupled to at least one of the housing and the first door and is actuatable between a locked configuration and an unlocked configuration.

Abstract: A reflective wire grid polarizer (WGP) can include an array of wires 12 on a face of a substrate 11, with channels 15 between adjacent wires 12. The wires 12 can have certain characteristics for WGP performance, such as index of refraction, alternating high/low index continuous thin films, thickness of layer(s), duty cycle, reflective rib shape, a curved side of transparent ribs 21 or 32, aspect ratio, or combinations thereof.

Abstract: A dental water jet is provided. The dental water jet may include a base unit, a reservoir supported by the base unit, a handle supported by the base unit, and a container covering an opening of the reservoir. The container may include a base supported by the reservoir and a lid movable relative to the base. The container may be configured to store one or more tips for use with the handle.

Abstract: A surface treatment robot includes a chassis having forward and rear ends and a drive system carried by the chassis. The drive system includes right and left driven wheels and is configured to maneuver the robot over a cleaning surface. The robot includes a vacuum assembly, a collection volume, a supply volume, an applicator, and a wetting element, each carried by the chassis. The wetting element engages the cleaning surface to distribute a cleaning liquid applied to the surface by the applicator. The wetting element distributes the cleaning liquid along at least a portion of the cleaning surface when the robot is driven in a forward direction. The wetting element is arranged substantially forward of a transverse axis defined by the right and left driven wheels, and the wetting element slidably supports at least about ten percent of the mass of the robot above the cleaning surface.

Abstract: A bone fusion method, system and device for insertion between bones that are to be fused together and/or in place of one or more of the bones, such as, for example, the vertebrae of a spinal column. The bone fusion device comprises one or more extendable tabs having a central rib. The bone fusion device includes one or more support channels configured to receive an insertion instrument that is then secured to the bone fusion device via a coupling mechanism. As a result, the coupled device is able to be securely positioned between vertebrae using the insertion instrument with minimal risk of slippage.

Abstract: A wire grid polarizer (WGP) can include an array of support-ribs on a substrate. Sides of the support-ribs can be inclined to one side. A wire can be applied on an upper-side and distal end of each support-rib, each wire being separate from wires on adjacent support-ribs. The WGP can be made with reduced or no etching.

Abstract: In some aspects, isomyosmine or a pharmaceutically acceptable salt thereof may be administered to an individual for the treatment of diseases of the visual system.

Abstract: In an embodiment, a system may support programmable hashing of address bits at a plurality of levels of granularity to map memory addresses to memory controllers and ultimately at least to memory devices. The hashing may be programmed to distribute pages of memory across the memory controllers, and consecutive blocks of the page may be mapped to physically distant memory controllers. In an embodiment, address bits may be dropped from each level of granularity, forming a compacted pipe address to save power within the memory controller. In an embodiment, a memory folding scheme may be employed to reduce the number of active memory devices and/or memory controllers in the system when the full complement of memory is not needed.

Abstract: A bone fusion method, system and device for insertion between bones that are to be fused together and/or in place of one or more of the bones, such as, for example, the vertebrae of a spinal column. The bone fusion device comprises one or more extendable tabs having a central rib. The bone fusion device includes one or more support channels configured to receive an insertion instrument that is then secured to the bone fusion device via a coupling mechanism. As a result, the coupled device is able to be securely positioned between vertebrae using the insertion instrument with minimal risk of slippage.

Abstract: The invention provides method for making high coercivity magnetic materials based on FeNi alloys having a L10 phase structure, tetratenite, and provides a system for accelerating production of these materials. The FeNi alloy is made by preparing a melt comprising Fe, Ni, and optionally one or more elements selected from the group consisting of Ti, V, Al, B, C, Mo, Ir, and Nb; cooling the melt and applying extensional stress and a magnetic field. This is followed by heating and cooling to form the L10 structure.

Abstract: Some embodiments include a metering system including a base housing configured to be coupled to a supply of a consumable, and including a plurality of meter slots, wherein each meter slot is configured to couple with a removeable meter module. Further, the metering system includes a removeable cover housing configured to removably couple to the base housing, and a meter module that includes at least one meter core and at least one data transfer functionality or assembly. The meter module can independently meter at least a portion of the consumable consumed by at least one consumer. A metering assembly with a removeable meter module and an associated meter slot can independently meter at least a portion of a consumable consumed by at least one consumer, and metering of the consumable to a consumer from one meter slot is independent of metering of the consumable from another meter slot.