Abstract: The present disclosure relates to a class of pyrimidine compounds, their stereoisomers, tautomers, pharmaceutically acceptable salts, stereoisomers, solvates, and hydrates thereof. The present disclosure also relates to a process of preparation of these pyrimidine compounds, pharmaceutical compositions containing them, and medicinal applications thereof.

Abstract: Techniques are described for classification-based data security management. The classification-based data security management can include utilizing device and/or data attributes to identify security modes for communication of data stored in a source device. The security modes can be identified based on a hybrid-encryption negotiation. The attributes can include a device resource availability value, an access trust score, a data confidentiality score, a geo-coordinates value, and/or a date/time value. The security modes can include a hybrid-encryption mode. The source device can utilize the hybrid-encryption mode to transmit the data, via one or more network nodes, such as an edge node, to one or more service nodes.

Abstract: The present disclosure provides compounds and methods useful for inhibiting SARM1 and/or treating and/or preventing axonal degeneration.

Abstract: In a distributed ledger (DLT) network, a transaction, related to movement of a monitored entity from a first party's location to a second party's location, is monitored. The transaction is associated with a respective real-time status and with at least a first predetermined milestone. Sensor outputs from an IoT enabled sensor that is operably coupled to the monitored entity, are received while the monitored entity is located remotely from the first and second parties during its movement from the first location to the second location. Updates to a real-time status of the monitored entity, relating to progress towards a milestone, are determined based on the received sensor outputs. The transaction is updated, in real time, on the DLT network when the milestone is reached. Information is communicated relating to the update of the transaction and the first predetermined milestone, in real-time, to the first party and the second party.

Abstract: A method includes: generating a transition probability matrix defining a set of transition probabilities for a set of techniques, each transition probability representing a probability of transitioning from a technique i to a technique j; defining a set of emission probability vectors corresponding to the set of techniques, each emission probability vector representing a probability of detecting a technique i and a probability of preventing a technique i; defining an initial technique vector representing an initial probability distribution of techniques; generating a hidden Markov model correlating a target sequence of observations with a hidden state sequence of techniques based on the transition probability matrix, the set of emission probability vectors, and the initial technique vector; and calculating a sequence of techniques, based on the hidden Markov model, exhibiting greatest probability to yield, for each technique in the sequence of techniques, absence of detection or prevention of the technique.

Abstract: Edge service deployment with network slice invocation is provided, which includes obtaining one or more service-related parameters for network slice invocation to support an edge service instance, and requesting a network slice from a network based on the obtained one or more service-related parameters. The requesting from the network is via a collaboration platform. Further, the edge service deployment and network slice invocation includes receiving from the network, based on requesting of the network slice, network slice invocation codes, and initiating activating of the edge service instance over the network slice of the network using the network slice invocation codes.

Abstract: The semiconductor cooling arrangement comprises one or more semiconductor assemblies, a housing, and one or more baffles. Each semiconductor assembly comprises a heatsink, a semiconductor die, an encapsulant, and electrical connections. The semiconductor die is bonded to the heatsink and contains a semiconductor power device. The encapsulant covers the semiconductor die. The side of the heatsink to which the semiconductor die is bonded extends beyond the encapsulant. The electrical connections pass through the encapsulant and to the semiconductor die. The housing has a chamber for housing the one or more assemblies. Each baffle comprises through-holes arranged such that fluid flows through the through-holes to a region of a respective semiconductor assembly to which the semiconductor power device is mounted, or to a region of the heatsink of the semiconductor assembly opposite a location to which the semiconductor power device is mounted.

Abstract: Methods and apparatus relating to data streaming accelerators are described. In an embodiment, a hardware accelerator such as a Data Streaming Accelerator (DSA) logic circuitry performs data movement and/or data transformation for data to be transferred between a processor (having one or more processor cores) and a storage device. Other embodiments are also disclosed and claimed.

Abstract: Updating user-specific instances of a second application for individual users of a group based on a data file for the second application being shared via a collaboration object that corresponds to the group within a first application. The instances of the second application present each individual user with their own custom user experience that is configured to provide access to specific content based on object permissions data. An application extension is executable, by the first application, to extend content editing functionalities of the second application into the collaboration object. Responsive to specific content being associated with the collaboration object via the application extension, each of the instances of the second application may be automatically updated to provide direct access to the specific content. Thus, each user within the group defined for collaboration object can access the data file via the collaboration object and their own instance of the second application.

Abstract: The present technology is directed to providing fault management with dynamic restricted access in a tenant network. The tenant network can be a private 5G cellular network or other wireless communication network. The present technology can identify a fault event within the tenant network based on received telemetry data, associate the fault event with a vendor component included in the tenant network, and generate a vendor fault context. The vendor fault context can be generated to include only the portion of telemetry data that is determined to be related to the fault event or the vendor component. The present technology can further use the vendor fault context to create a time-bound user account for remotely accessing the tenant network for fault triage and management. The time-bound user account can be associated to a static role-based access control (RBAC) scheme configured with access restrictions determined based on the vendor fault context.

Abstract: Apparatuses, methods and systems comprising integrated motorized conveyor rollers are provided. The example integrated motorized conveyor roller comprises: a housing; a motor assembly and a drive assembly at least partially disposed within the housing that are configured to cause rotation of at least a portion of the integrated motorized conveyor roller; at least one sensing element operatively coupled to the integrated motorized conveyor roller; and a controller component in electronic communication with the at least one sensing element, the motor assembly and the drive assembly, wherein the controller component is configured to obtain operational data via the at least one sensing element.

Abstract: The present invention provides compounds useful as inhibitors of PAD4, compositions thereof, and methods of treating PAD4-related disorders.

Abstract: A system on a chip (SoC) includes a first domain comprising a first processor configured to boot the SoC, and a first debug subsystem, a second domain comprising a second processor, the second domain configurable as either a safety domain or a general-purpose processing domain, and isolation circuitry between the first domain and the second domain. During boot-up of the SoC, the first processor provides code to the second domain which, when executed by the second processor, configures the second domain as either a safety domain or as a general-purpose processing domain.

Abstract: A vehicle door includes a belt structure and a rigid handle having a rigid base and a rigid outer grip portion. The rigid outer grip portion includes a portion that is spaced apart from the base to form a gap. The base of the handle is rigidly connected to the belt structure whereby the outer grip portion of the handle does not move relative to the belt structure. The vehicle door may include a powered door opening mechanism that moves a portion of the door away from a vehicle body when actuated.

Abstract: An electronic device and method for providing a user interface for a cognitive search in content is provided. The electronic device controls a display device to render an application interface that includes UI elements. The UI elements include a UI element to select media items, a UI element to select input data to be used for search inside content of each media item, and interactive UI elements to configure parameters that control the search inside the content or a metasearch within results of the search. The electronic device receives an input via the UI elements and transmits a search request to a search engine system. The electronic device receives a search result that identifies, from within the content or associated metadata, content elements that match the input data and satisfy the parameters. The display device is controlled to render the search result onto the application interface.

Abstract: Embodiments provide methods, and server systems connecting with a customer service representative/agent for a financial transaction. A method includes sending, by a server system, a message related to a financial transaction to a user device using a messaging protocol. The message includes at least one option to receive a response of the message from the user device for connecting with an agent. The method includes receiving the response of the message from the user device. The response includes an authentication data. The method includes verifying the authentication data. Upon successful verification, the method includes electronically extracting at least one context of the message from the response. The method includes sending the at least one context to a Customer Service Centre (CSC) server. The CSC server is configured to assign the agent to the user based on the at least one context for an upcoming conversation about the message.

Abstract: Various embodiments of a hermetically-sealed package and a method of forming such package are disclosed. The package includes a housing that extends along a housing axis between a first end and a second end, where the housing includes first and second opaque portions and a transparent portion disposed between the first and second opaque portions. The first opaque portion is hermetically sealed to a first end of the transparent portion and the second opaque portion is hermetically sealed to a second end of the transparent portion. At least one of the first and second opaque portions is hermetically sealed to the transparent portion by a weld ring. The package further includes a power source disposed within the housing, and an inductive coil disposed at least partially within the transparent portion of the housing and electrically connected to the power source.

Abstract: In a general aspect, a vapor cell includes a body defined by a stack of layers that includes electrically conductive layers and electrically insulating layers. The stack of layers are bonded to each other and have first and second end layers at respective opposite ends of the body. The stack of layers also has intermediate layers between the first and second end layers that define an internal cavity of the body. The internal cavity extends through the body between the first and second end layers and includes a vapor or a source of the vapor disposed therein. Adjacent electrically conductive layers are separated by at least one electrically insulating layer. Moreover, each electrically conductive layer defines an electrode of the vapor cell and includes a contact surface on an exterior side of the body. The contact surface defines an electrical contact of the electrode.

Abstract: A device may receive project management data associated with development of a software product and may process a first portion of the project management data, with first models, to generate timeliness scores and an overall timeliness score for the software product. The device may process a second portion of the project management data, with second models, to generate quality scores and an overall quality score for the software product and may process a third portion of the project management data, with third models, to generate product readiness scores and an overall product readiness score for the software product. The device may utilize a fourth machine learning model, with the overall timeliness score, the overall quality score, and the overall product readiness score, to generate a success probability for the software product and may perform one or more actions based on the success probability for the software product.

Abstract: This disclosure relates to techniques for providing a framework for supporting custom signaling between a wireless device and a cellular network. A wireless device and a cellular base station may establish a wireless link. The wireless device and the cellular base station may perform custom signaling in accordance with the custom signaling framework.