Abstract: Systems and methods for low-cost HAGL measurement and terrain database updates are provided. In one example, a system includes an image capturing device configured to capture first and second images and a navigation system configured to generate pose data. The system further includes processor(s) communicatively coupled to the image capturing device and the navigation system and a non-transitory, computer-readable medium communicatively coupled to the processor(s) that stores instruction(s) which, when executed by the processor(s), cause the processor(s) to: estimate optical flow between the first and second images; determine rigid flow per image for each depth bin of a group of depth bins based on the pose data, wherein each depth bin corresponds to a particular depth range; and generate a dense depth map by determining a depth bin, for each pixel, that minimizes a difference between the estimated optical flow and the determined rigid flow for the respective pixel.

Abstract: The present application relates to antibodies specifically binding to the V-domain immunoglobulin-containing suppressor of T-cell activation (VISTA) at acidic pH and their use in cancer treatment. In some embodiments, the antibodies bind specifically to human VISTA at acidic pH, but do not significantly bind to human VISTA at neutral or physiological pH.

Abstract: A system may smartly edit the context of a conversation to be input into a chatbot LLM by using a conversation compression algorithm to prune and compress redundant elements. The system evaluates the conversation context compression algorithm using both a chatbot LLM and an adversarial LLM. The system retrieves a logged conversation and generates a compressed conversation context from the logged conversation. The system generates a synthetic user response by applying the adversarial LLM and generates a test conversation by replacing a user response in the conversation with the synthetic user response. The system generates a compressed context of the test conversation. The system generates a test chatbot LLM response by prompting the chatbot LLM with the compressed context of the test conversation. The system evaluates the conversation context compression algorithm by comparing the test chatbot response with a benchmark chatbot response.

Abstract: Fluid connectors assemblies that provide neutral fluid displacement without overlapping connectors are disclosed. A fluid connector assembly may include a housing and a pair of connectors (e.g., luers) coupled with the housing. A compressible member is located within the housing. The first connector and the second connector each include a post with an opening. The compressible member can seal off the opening of the first connector from fluid entry. However, when the post of the second connector is inserted into the housing, the post of the second connector displaces the compressible member, causing the compressible member to create a fluid path, thereby allowing fluid to flow through the internal volume of the housing. Further, the compressible member seals the housing until each of the first connector and the second connector are coupled therewith forming a fluid path through the posts.

Abstract: A cable hanger includes: a base panel having opposed ends; a pair of arms, each of the arms attached to a respective end of the base panel and having a free end; a pair of locking projections, each of the locking projections attached to a respective free end of the arms; and a pair of gripping members, each gripping member attached to a respective arm, each gripping member having opposed ends, wherein one of the ends of each gripping member is fixed to the arms and the other of the ends of each gripping member is fixed to the arm or to the base panel. The arms and locking projections are configured to spread apart to enable insertion of a cable between the arms, wherein the gripping projections engage and grip the cable, and wherein the locking projections are configured to be inserted into the aperture of the supporting structure.

Abstract: A system described herein may monitor a set of local Key Performance Indicators (“KPIs”) associated with an edge computing device. The local KPIs may not be provided to a central orchestrator that is communicatively coupled to multiple edge computing devices. The system may monitor application KPIs associated applications implemented by the edge computing device, which may be provided to the central orchestrator. The orchestration models may include conditions associated with the set of local KPIs, and orchestration actions to perform with respect to the particular edge computing based on the conditions. The system may perform orchestration actions on the particular edge computing device based on the monitored local KPIs and application KPIs. The central orchestrator may identify that the application KPIs are below a threshold and perform a second set of orchestration actions with respect to the edge computing device, or one or more other edge computing devices.

Abstract: An insert for mounting multiple cables in a cable hanger includes: a gripping portion configured to engage multiple cables; and a wrapping portion attached to the gripping portion and configured to wrap around the gripping portion as it receives cables.

Abstract: A data management system may support a configuration backup of a first backup system that manages backup procedures for data of a host environment that is separate from the first backup system. The data management system may transmit, to the first backup system, a request to generate the configuration backup that includes information for the one or more backup procedures managed by the first backup system. The data management system may cause the configuration backup to be stored in a separate storage location. In response to first backup system failure, the data management system may transmit, to a second backup system, a request to apply one or more configurations for the first backup system to the second backup system based on the stored configuration backup for the first backup system.

Abstract: Systems, apparatus, articles of manufacture, and methods are disclosed to generate and monitor security infrastructure. An example apparatus comprises programmable circuitry to at least one of instantiate or execute the machine readable instructions to: provision the security infrastructure based on a security infrastructure generation request; detect a global infrastructure template based on the security infrastructure generation request; and generate the security infrastructure based on the provisioned security infrastructure, the global infrastructure template, and an identified security infrastructure generation authorization, the security infrastructure generation authorization to indicate whether the generation of the security infrastructure is permitted.

Abstract: Threaded sacro-iliac joint stabilization (e.g., fusion, fixation) implants and methods of implantation and manufacture. Some implants include a threaded distal region, an optionally threaded central region, and an optionally threaded proximal region. The distal, central, and proximal regions have lengths such that when the implant is laterally implanted across a SI joint, the distal region can be positioned in a sacrum, the central region can be positioned across an SI-joint, and the proximal region can be positioned in an ilium.

Abstract: The present application relates to antibodies specifically binding to the V-domain immunoglobulin-containing suppressor of T-cell activation (VISTA) at acidic pH and their use in cancer treatment. In some embodiments, the antibodies bind specifically to human VISTA at acidic pH, but do not significantly bind to human VISTA at neutral or physiological pH.

Abstract: The present application relates to antibodies specifically binding to the V-domain immunoglobulin-containing suppressor of T-cell activation (VISTA) at acidic pH and their use in cancer treatment. In some embodiments, the antibodies bind specifically to human VISTA at acidic pH, but do not significantly bind to human VISTA at neutral or physiological pH.

Abstract: A data management system may support a configuration backup of a first backup system that manages backup procedures for data of a host environment that is separate from the first backup system. The data management system may transmit, to the first backup system, a request to generate the configuration backup that includes information for the one or more backup procedures managed by the first backup system. The data management system may cause the configuration backup to be stored in a separate storage location. In response to first backup system failure, the data management system may transmit, to a second backup system, a request to apply one or more configurations for the first backup system to the second backup system based on the stored configuration backup for the first backup system.

Abstract: A system described herein may monitor a set of local Key Performance Indicators (“KPIs”) associated with an edge computing device. The local KPIs may not be provided to a central orchestrator that is communicatively coupled to multiple edge computing devices. The system may monitor application KPIs associated applications implemented by the edge computing device, which may be provided to the central orchestrator. The orchestration models may include conditions associated with the set of local KPIs, and orchestration actions to perform with respect to the particular edge computing based on the conditions. The system may perform orchestration actions on the particular edge computing device based on the monitored local KPIs and application KPIs. The central orchestrator may identify that the application KPIs are below a threshold and perform a second set of orchestration actions with respect to the edge computing device, or one or more other edge computing devices.

Abstract: A method for analyzing whether, and to what extent, a transformation has occurred in the partner molecule component of an antibody-drug conjugate.

Abstract: The invention relates to an inhibitory chimeric antigen receptor (N-CAR) comprising an extracellular domain comprising an antigen binding domain, a transmembrane domain and, an intracellular domain wherein the intracellular domain comprises an Immunoreceptor Tyrosine-based Switch Motif ITSM, wherein said ITSM is a sequence of amino acid TX1YX2X3X4, wherein X1 is an amino acid X2 is an amino acid X3 is an amino acid and X4 is V or I.

Abstract: A search engine server includes a communication interface through which to receive a multi-modal query from a browser of a client device, the multi-modal query including at least a first image of an item. A processing device, coupled to the communication interface, is to: execute a neural network (NN) regressor model on the first image to identify a plurality of second items that are similar to and compatible with the item depicted in the first image, wherein a set of images correspond to the plurality of second items; generate structured text that explains, within one of a phrase or a sentence, why the set of images are relevant to the item; and return, to the browser of the client device via the communication interface, a set of search results comprising the set of images and the structured text.

Abstract: Disclosed are methods and systems for displaying content. In an aspect, a plurality of content items can be displayed on one user device according to user preference. An example method can comprise positioning a first set of pixels associated with a user device so that first content displayed via the first set of pixels can be viewable in a first viewing location. A second set of pixels associated with the user device can be positioned so that second content displayed via the second set of pixels can be viewable in a second viewing location. The second content can be different from the first content.

Abstract: The present application relates to antibodies specifically binding to the V-domain immunoglobulin-containing suppressor of T-cell activation (VISTA) at acidic pH and their use in cancer treatment. In some embodiments, the antibodies bind specifically to human VISTA at acidic pH, but do not significantly bind to human VISTA at neutral or physiological pH.

Abstract: A computer-based system, and a computer-implemented method, mentors students, particularly women and ethnic and racial minorities, intending to enter healthcare professions. The system uses a gamified mobile-enabled web application (App) that serves as a visual and interactive dashboard populated with checklists, career support resources, strategies, tips, and a mentoring platform to educate, encourage, empower, and facilitate the entry of students into the healthcare professions.