Abstract: The present invention relates to a medium for inducing differentiation of dedifferentiated stem cells into mesenchymal stem cells, a method for preparing mesenchymal stem cells from dedifferentiated stem cells by using the same, and mesenchymal stem cells prepared by using the same. The mesenchymal stem cells prepared using the above medium and method can be differentiated into various target cells, and thus can be useful as a cell therapeutic agent for congenital and acquired musculoskeletal diseases and injuries.

Abstract: An image sensor structure including: a substrate, having a first conductive type; a first well region and a second well region disposed in the substrate and spaced apart; an isolation region disposed in the first well region; a gate disposed on the substrate and between the first well region and the second well region; and a pinned photodiode disposed in the substrate and between the first well region and the second well region is provided. The pinned photodiode includes: a first doping region disposed in the substrate and having a first doping concentration and the first conductive type; and a second doping region disposed on the first doping region and having a second doping concentration opposite to the first conductive type. One or both of the first doping region and the second doping region is non-uniform and the first doping concentration is greater than the second doping concentration.

Abstract: An image-sensing device is provided. The image-sensing device includes a substrate, a light-sensing element, a first dielectric layer, a light-guiding structure, and a patterned conductive layer. The light-sensing element is disposed in the substrate. The first dielectric layer is disposed on the first side of the substrate. The light-guiding structure is disposed in the first dielectric layer. The patterned conductive layer is disposed between the light-sensing element and the light-guiding structure. In addition, the patterned conductive layer includes a subwavelength structure. An image-sensing system including the above image-sensing device is also provided.

Abstract: An image sensor includes a semiconductor substrate, a first annular doped area, a second annular doped area, an annular isolation area, a photoelectric conversion area, a voltage conversion area, and a gate structure. The first annular doped area is disposed in the semiconductor substrate and includes a first type dopant. The second annular doped area is disposed in the semiconductor substrate, and over the first annular doped area, the second annular doped region includes a second type dopant. The annular isolation area is disposed in the semiconductor substrate and over the second annular doped area. The photoelectric conversion area is disposed in the semiconductor substrate surrounded by the annular isolation area. The voltage conversion area is disposed in the semiconductor substrate surrounded by the annular isolation area. The gate structure is disposed on the semiconductor substrate.

Abstract: A global shutter CMOS image sensor includes a photodiode, a floating diffusion region, and a storage diode disposed in the upper portion of the substrate. The storage diode is disposed between the photodiode and the floating diffusion region. A first transfer gate is disposed on the substrate between the photodiode and the storage node. A second transfer gate is disposed on the substrate between the storage diode and the floating diffusion region. A first dielectric layer is disposed on the substrate and covers the first transfer gate and the second transfer gate. A light-shielding layer is disposed on the first dielectric layer. A light pipe is disposed through the light-shielding layer and a portion of the first dielectric layer, and is correspondingly disposed above the photodiode. The light pipe has a higher refractive index than the first dielectric layer.

Abstract: A three-dimensional cell culture method on the basis of a biodegradable synthetic hydrogel is provided. The method may include culturing cells in a cell culture dish in a non-contact manner using a porous membrane and a biodegradable synthetic hydrogel in the culture of stem cells and primary cells.

Abstract: A global shutter CMOS image sensor includes a photodiode, a floating diffusion region, and a storage diode disposed in the upper portion of the substrate. The storage diode is disposed between the photodiode and the floating diffusion region. A first transfer gate is disposed on the substrate between the photodiode and the storage node. A second transfer gate is disposed on the substrate between the storage diode and the floating diffusion region. A first dielectric layer is disposed on the substrate and covers the first transfer gate and the second transfer gate. A light-shielding layer is disposed on the first dielectric layer. A light pipe is disposed through the light-shielding layer and a portion of the first dielectric layer, and is correspondingly disposed above the photodiode. The light pipe has a higher refractive index than the first dielectric layer.

Abstract: The present invention relates to a method for inducing osteogenic differentiation of mesenchymal stem cells and, more particularly, to a short-time osteogenic differentiation method of culturing cells using a porous membrane and a biodegradable synthetic biogel, whereby the cells do not contact a cell culture container. The present invention can significantly shorten the induction period of osteogenic differentiation, compared to the conventional osteogenic differentiation method, and has an effect of the cells being easily separable after differentiation as well.

Abstract: A method comprising receiving physiologic information at a social-networking system from a body-associated personal communicator is disclosed. A social-networking system configured to receive physiological information from a body-associated personal communicator and a body-associated personal communicator configured to receive physiologic information and communicate the physiologic information to a social-networking system also are disclosed.

Abstract: A method comprising receiving physiologic information at a social-networking system from a body-associated personal communicator is disclosed. A social-networking system configured to receive physiological information from a body-associated personal communicator and a body-associated personal communicator configured to receive physiologic information and communicate the physiologic information to a social-networking system also are disclosed.

Abstract: Methods and systems for dynamically updating a virtual keyboard implemented by an application running on a mobile device are provided. A first configuration file can be loaded that can have a default configuration of the virtual keyboard that displays design assets. A second configuration file can then be loaded with an updated configuration of the virtual keyboard with updated design assets.

Abstract: The present invention relates to a method for inducing osteogenic differentiation of mesenchymal stem cells and, more particularly, to a short-time osteogenic differentiation method of culturing cells using a porous membrane and a biodegradable synthetic biogel, whereby the cells do not contact a cell culture container. The present invention can significantly shorten the induction period of osteogenic differentiation, compared to the conventional osteogenic differentiation method, and has an effect of the cells being easily separable after differentiation as well.

Abstract: The present invention relates to a composition for preserving cells and a cell preservation method and, more specifically: to a composition for preserving cells, containing, as active ingredients, a plant-derived recombinant human serum albumin and a plant peptide, which maintain a high cell survival rate while maintaining animal-free and xeno-free properties and are stable without changes in cell morphology or a surface expression factor during the short term preservation of cells such as stem cells or primary cultured cells; and a cell preservation method using the same.

Abstract: An image-sensing device includes a semiconductor substrate including an image-sensing region and a peripheral circuit region surrounding the image-sensing region. The image-sensing device further includes an image-sensing element disposed in the semiconductor substrate in the image-sensing region, and an imaging processing element disposed in the semiconductor substrate in the peripheral circuit region. The image-sensing device further includes a first isolation element disposed in the semiconductor substrate in the peripheral circuit region and adjacent to the image-sensing element in the image-sensing region. The first isolation element includes a metal portion having a coefficient of heat conduction greater than 149 W/m·K, and an imaginary part of a permittivity (Im(?)) of the metal portion under a light wavelength of 1100 nm is greater than 0.004.

Abstract: The present invention relates to a composition for preserving cells and a method for preserving cells and, more specifically, to: a composition for preserving cells, containing, as active ingredients, plant-derived recombinant human serum albumin and plant peptides, wherein the composition maintains a high cellular survival rate while maintaining animal-free and xeno-free properties and is stable without changes in cellular morphology or surface expression factors in the short-term preservation of cells such as stem cells or primary cultured cells; and a method for preserving cells by using the same.