Abstract: A system and method for distribution of multimedia content over a computer communications network using a portable web widget, the web widget adapted for viral distribution and execution in a web browser on a client device, the client device having a processor and a memory and the web widget having at least an active operational mode and an inactive operational mode. The web widget includes a content retrieval component communicatively coupled to an application server over the computer communications network, a content retrieval component configured to retrieve a multimedia content file and associated metadata from a storage resource to the memory of the client device after the web widget enters the active operational mode, a content preview component configured by the client device processor to execute a portion of the retrieved multimedia content file, and a transaction processing component operative to initiate a commercial transaction pertaining to the multimedia content file.

Abstract: Embodiments of this invention provide novel peptidomimetics that contain a macrocycle, an embodiment of which is 2S,9?S,12?S)-2-{[(1?,4?-Diaza-2?-oxobicyclo[7.3.0]dodecyl)-12?-carbonyl]amino}-1,5-pentanedioic acid trifluoroacetate. Such compounds are neuroprotective and have utility as therapeutic agents for treatment of diseases, injuries and other conditions characterized by neuronal degeneration and/or neuronal cell death caused by in embodiments, toxicity or hypoxia. Compounds are also useful for manufacture of medicaments useful for treatment of such conditions.

Abstract: Embodiments of the present invention provide indexing, organizing, storing and/or retrieving of environmental information regarding a proposed environment-modifying project, including information about an environment-modifying natural event or construction project (“project”); a natural, constructed or socioeconomic feature in the area of the project (“setting”); a change to the setting brought about by the project (“impact”); or a feature designed to ameliorate a potential environmental impact of the project (“mitigation”). The environmental information is indexed with metadata that may be hierarchically organized and made available to a reviewer in a controlled vocabulary or a user-defined vocabulary.

Abstract: Embodiments of this invention include synthetic compounds (NRP analogues) of peptides termed neural regeneration peptides (NRPs). NRP analogues are made by substituting amino acids in the native peptide sequence, modifying amino acids chemically, by replacing amino acids with synthetic moieties, by stabilizing ?-turns, acetylation of terminal glycine residues or by cyclization. NRP analogues can be used to treat a variety of conditions involving degeneration of neural cells, and includes treating disorders of the nervous system, including peripheral neuropathy, multiple sclerosis, diabetic peripheral neuropathy, neurotoxin-induced neurodegeneration, and amyotrophic lateral sclerosis.

Abstract: A method of delivering advertising in an online environment includes determining a context of a user operating a client computer to interact with an e-commerce website, where the determined context representing an intent of the user to locate a product for purchase, defining a relation between one or more of a plurality of advertisements and the product based on at least one of a plurality of relevance types, and displaying, to the user, at least one of the advertisements having the relation to the product.

Abstract: A method of delivering advertising in an online environment includes determining an intent of a user interacting with an e-commerce website and determining a hurdle rate, based at least on the intent of the user, that identifies a threshold amount to be bid by an advertiser in order to display an advertisement to the user interacting with the e-commerce website. The method may further include selecting, from a plurality of advertisements, one or more optimal advertisements having a combined advertiser bid that exceeds the determined hurdle rate. The method may further include providing one or more controls in a user interface of a client computer system, each of the controls being associated with a respective advertisement of the one or more optimal advertisements and adapted to enable the user to select one or more of the controls, and providing an element, responsive to an input of the user, that is adapted to display, to the user, the respective advertisements selected by the user.

Abstract: Embodiments of this invention provide novel peptidomimetics that contain a macrocycle. Such compounds are neuroprotective and have utility as therapeutic agents for treatment of diseases, injuries and other conditions characterised by neuronal degeneration and/or death. Compounds are also useful for manufacture of medicaments useful for treatment of such conditions.

Abstract: A method of delivering advertising in an online environment includes determining an intent of a user interacting with an e-commerce website, and determining a hurdle rate that is based at least on the user intent and which identifies a threshold amount to be bid by an advertiser in order to display an advertisement to the user. The method further includes selecting, from a plurality of advertisements, an optimal advertisement having an advertiser bid that exceeds the hurdle rate, and displaying the optimal advertisement to the user in an interface of a client computer system.

Abstract: Embodiments of this invention include novel analogs of Glycyl-Prolyl-Glutamate (GPE) and compositions containing such analogs of GPE. Of these, certain analogs have modified proline residues. Other embodiments of this invention include uses of analogs of GPE to protect neural cells from degeneration and/or death in response to injury or disease. Disorders treatable with compounds and compositions of this invention include hypoxia/ischemia, toxic injury, and chronic neurodegenerative disorders including Parkinson's disease.

Abstract: An ink jet printer comprising a printing fluid cartridge receiving portion arranged to receive a printing fluid cartridge (2) and to allow passage of printing fluid from a received printing fluid cartridge to printing fluid conduits of the ink jet printer; a data reader arranged to read data indicating a quantity of fluid within a received cartridge from an electronic data storage device associated with the received printing fluid cartridge; and a controller arranged to generate update data usable to modify data stored on said electronic data storage device and to modify data stored on said electronic storage device based upon said update data such that data stored on said electronic data storage device indicates an updated quantity of fluid in said printing fluid cartridge.

Abstract: A method and device for the quantitative determination of an ion in a fluid which comprises subjecting the fluid to voltammetry using a sensing electrode which comprises an electrically conducting support having a surface which is coated with a support matrix, the support matrix containing an electroactive species capable of being oxidised or reduced to form a charged species, and an ionophore.

Abstract: An electrical surge protection device (12) confers protection to an output node (13) from electrical surges on a data or power line (10) incident on an input node (11). A transistorized surge protection device (18) is located in a current path between the input node (11) and the output node (13) and is configured to assume an isolating state in response to an over-current therethrough. A voltage-triggered protective circuit comprising a diac (16) in series with a bi-directional zener diode (14) is connected between the output side of the transistorized surge protection device (18) and a surge sinking node (15). The voltage-triggered circuit assumes a low-impedance state in response to an electrical surge at output terminal 13. Consequently a surge current is passed through zener diode (14) and surge diac (16) to the surge sinking node. In response to the surge current the transistorized surge protection device (18) assumes a high impedance configuration thereby isolating output node (13) from input node (11).

Abstract: An apparatus and method for high-voltage transient blocking employing a transient blocking unit (TBU) that has at least one depletion mode n-channel device interconnected with at least one depletion mode p-channel device such that a transient alters a bias voltage Vp of the p-channel device and a bias voltage Vn of the n-channel device in concert. Specifically, the bias voltages are altered such that the p-channel device and n-channel device mutually switch off to block the transient. The depletion mode n-channel device employs a set of cascaded low-voltage depletion mode field effect transistors (FETs) such as metal-oxide-silicon field effect transistors (MOSFETs) connected source-to-drain to achieve the desired high-voltage operation of the TBU.

Abstract: A transient blocking unit (TBU) includes at least two depletion mode transistors connected to each other such that they can rapidly switch from a normal low-impedance state to a high-impedance current blocking state in response to an over-voltage or over-current condition. This behavior makes TBUs useful for protecting electrical devices and circuit from harmful electrical transients. Some kinds of transistors can exhibit a phenomenon known as current collapse, where channel conductance is temporarily reduced after exposure to high voltage. Although current collapse is undesirable, transistors exhibiting current collapse can have otherwise favorable properties for TBU applications. According to the present invention, a TBU is provided where a diode is placed in parallel with a TBU transistor that can exhibit current collapse. The diode prevents high power dissipation in a current collapsed transistor, thereby reducing the vulnerability of the TBU to permanent damage or destruction in service.

Abstract: The present invention provides compounds of formula (I) wherein A is (1), (2), (3), (4), (5), (6) or (7) and wherein R1, R7, y and Ar1 are defined herein. The compounds are inhibitors of the uptake of one or more monoamines selected from serotonin, norepinephrine and dopamine and, as such, may be useful in the treatment of disorders of the central and/or peripheral nervous system.

Abstract: A method and apparatus for transient blocking relying on a transient blocking device and a sampling circuit. The transient blocking device has at least one depletion mode n-channel device interconnected with at least one depletion mode p-channel device such that a transient alters a bias voltage Vp of the depletion mode p-channel device and a bias voltage Vn of the depletion mode n-channel device in such a manner that the depletion mode devices mutually switch off to block the transient. The sampling circuit is interconnected with the depletion mode p-channel device and the depletion mode n-channel device to determine whether the transient persists. In the event of a persistent transient, the sampling circuit uses a disconnect element for permanently blocking the transient blocking device.

Abstract: An animal detection and deterrent system enabling an out of doors area to be protected from intruding animals. A primary laser beam FIG. 1 (1.14) is produced from master laser/sensor (1.10), and precisely forwarded around an area of any configuration and topography via forwarders (1.11), (1.12), (1.13) or FIG. 10 (10.39), (10.40) and (10.41). Master laser/sensor (1.10) and all forwarders, contain mechanisms to accurately adjust the direction of laser beams and position of light sensors. Light sensors contain filters to block ambient light and admit only laser light to allow operation in bright sunlight or darkness. When the system is in a stable “on condition”, the laser beam ultimately strikes light sensor (6.65) in the master sensor (1.20). An animal interrupting the laser beam, at any point in the periphery, prevents laser light to strike light sensor (6.65) in master sensor (1.20). This causes light sensor (6.65) to initiate an electronic signal to an electronic circuit, FIG. 14, and microprocessor (14.

Abstract: A transient blocking unit (TBU) having reduced series impedance is provided. A TBU includes two or more depletion mode transistors arranged to provide a low series impedance in normal operation and a high series impedance when the input current exceeds a predetermined threshold. A nonlinear impedance element is included in the TBU that acts as a current limiter having a substantially constant saturation current over a range of applied voltages. This saturation current is selected to be the threshold current of the TBU. When the threshold is exceeded, the voltage developed across the nonlinear impedance element tends to drive the TBU into its high impedance state. When the operating current is below threshold, the TBU series resistance is relatively low because the nonlinear impedance element is in its low-resistance state. The nonlinear impedance element can be a separate circuit element, or it can be integrated with one or more of the TBU transistors.

Abstract: Embodiments of this invention provide novel peptidomimetics that contain a macrocycle. Such compounds are neuroprotective and have utility as therapeutic agents for treatment of diseases, injuries and other conditions characterised by neuronal degeneration and/or death. Compounds are also useful for manufacture of medicaments useful for treatment of such conditions.

Abstract: A transient blocking unit (TBU) is a transistor circuit that is normally on, but rapidly and automatically switches to a high-resistance current blocking state when a current threshold is exceeded, thereby protecting a series connected load from over-voltage or over-current conditions. Process variation of transistor threshold voltage and on-resistance can cause undesirable variation of the TBU threshold current and/or of TBU resistance. Control of TBU threshold current and/or resistance is improved by providing for trimming the TBU during its fabrication to provide a one-time adjustment of the threshold current or resistance. Such trimming can be done with a resistive trimming circuit placed in series with the on-resistance of the relevant TBU transistor. Alternatively, a segmented TBU transistor having an on-resistance that is adjustable by way of wire bonding during fabrication can be employed.