Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for generating long textual works using language model neural networks. For example, the textual works can be generated hierarchically by performing a hierarchy of generation steps using the same language model neural network.

Abstract: The present invention relates to certain 2-(2,4,5-substituted-anilino)pyrimidine compounds and pharmaceutically acceptable salts thereof which may be useful in the treatment or prevention of a disease or medical condition mediated through certain mutated forms of epidermal growth factor receptor (for example the L858R activating mutant, the Exon19 deletion activating mutant and the T790M resistance mutant). Such compounds and salts thereof may be useful in the treatment or prevention of a number of different cancers. The invention also relates to pharmaceutical compositions comprising said compounds and salts thereof, especially useful polymorphic forms of these compounds and salts, intermediates useful in the manufacture of said compounds and to methods of treatment of diseases mediated by various different forms of EGFR using said compounds and salts thereof.

Abstract: Vibration absorbers comprising torsional viscous damper of the tube-type are tuned using one or more elastic members to improve the ability of the vibration absorbers to reduce problematic torsional vibrations. The torsional stiffness of the vibration absorbers is designed to meet a requirement between the frequency to be removed and the polar moment of inertia of the tube-type damper.

Abstract: The present disclosure relates to plant-based protein compositions that when used in a beverage, create a beverage product with a superior mouthfeel.

Abstract: The present invention is directed to a new fluoro-pyridinone hydroxamic acid phosphates and boronates of Formulae I, II and III wherein Q is selected from the group consisting of —P(O)(OH)2, —P(O)(OH)(O?M+), —P(O)(O?M+)2 and —P(O)(O?)2M2+; M+ at each occurrence is a pharmaceutically acceptable monovalent cation; and M2+ is a pharmaceutically acceptable divalent cation and their use as LpxC inhibitors and, more specifically, their use to treat bacterial infections.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for predicting a structure of a protein that comprises a plurality of amino acid chains.

Abstract: In particular embodiments, a computing system may capture a first image of a scene using a first camera of an artificial reality device. The system may capture a second image of the scene using a second camera and one or more optical elements of the artificial reality device. The second image may include an overlapping portion of multiple shifted copies of the scene. The system may generate an upsampled first image by applying a particular sampling technique to the first image. The system may generate a tiled image comprising a plurality of repeated second images by applying a tiling process to the second image. The system may generate an initial output image by processing the upsampled first image and the tiled image using a machine learning model. The system may generate a final output image by normalizing the initial output image using the upsampled first image.

Abstract: In one embodiment, a method includes accessing a map of a building floor plan with locations of access points within the floor plan, the access points being capable of performing wireless communications with wireless devices. Determining a pose of a wireless device within the map using images captured by one or more cameras of the wireless device. Selecting a preferred access point based on the pose of the wireless device, the floor plan, and the locations of the plurality of access points within the floor plan. Configuring wireless communication settings of the wireless device to communicate with the preferred access point based on the pose of the wireless device and the location of the preferred access point within the floor plan.

Abstract: A distributed imaging system for augmented reality devices is disclosed. The system includes a computing module in communication with a plurality of spatially distributed sensing devices. The computing module is configured to process input images from the sensing devices based on performing a local feature matching computation to generate corresponding first output images. The computing module is further configured to process the input images based on performing an optical flow correspondence computation to generate corresponding second output images. The computing module is further configured to computationally combine first and second output images to generate third output images.

Abstract: A system and apparatus assists pilots and flight crews in determining the best course of action at any particular point inflight for any category of emergency. The system monitors a plurality of static and dynamic flight parameters including atmospheric conditions along the flight path, ground conditions and terrain, conditions aboard the aircraft, and pilot/crew data. Based on these parameters, the system may provide continually updated information to the pilot or crew about the best available landing sites or recommend solutions to aircraft configuration errors. In case of emergency, the system may provide the pilot with procedure sets associated with a hierarchy of available emergency landing sites (or execute these procedure sets via the autopilot system) depending on the specific nature of the emergency.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for selecting actions from large discrete action sets. One of the methods includes receiving a particular observation representing a particular state of an environment; and selecting an action from a discrete set of actions to be performed by an agent interacting with the environment, comprising: processing the particular observation using an actor policy network to generate an ideal point; determining, from the points that represent actions in the set, the k nearest points to the ideal point; for each nearest point of the k nearest points: processing the nearest point and the particular observation using a Q network to generate a respective Q value for the action represented by the nearest point; and selecting the action to be performed by the agent from the k actions represented by the k nearest points based on the Q values.

Abstract: A method of identifying a particular mask for a patient for use in delivering a flow of breathing gas to the patient includes capturing with a visual presentation and interaction component a plurality of images of the patient; receiving with the visual presentation and interaction component a number of responses from the patient to questions presented to the patient, eliminating one or more masks from a pool of potential masks for the patent based on at least one of the responses, utilizing at least some images of the plurality of images to determine the particular mask for the patient from the pool of potential masks, and identifying the particular mask to the patient.

Abstract: Various embodiments of the present invention generally relate to identity authentication and/or recognition. Some embodiments provide a method for determining when a user may engage in a restricted activity, including engaging in an initial contact with a user via a medium for exchange, receiving a request to engage in an activity, determining an activity trust threshold required for the activity, determining an initial identity trust score for the user, and comparing the initial identity trust score with the activity trust threshold. Based on the comparison, the user is either allowed to engage in the activity, rejected from engaging in the activity, or additional identifying information is collected.

Abstract: A method and device for accurately monitoring, displaying, and remote reporting of turbulent material flow streams in confined channels and pipes is provided. The device can have multiple cams coupled to an obstruction, and a spring. The multiple cams can have a cam profile, and the cam profile and the spring may be selected to linearize a rotation of the obstruction over a range of fluid flow velocities. The obstruction can include have multiple obstructions each in a different area of a cross-section of a pipe, improving the accuracy of the device.

Abstract: A media-isolated pressure and force sensor is provided utilizing a deformable solid as a coupling mechanism for transmitting a received external pressure to the surface of a pressure sensing diaphragm. An example media-isolated pressure and force sensor may include a pressure sensing diaphragm that is coupled to a substrate of the media-isolated pressure sensor and a deformable solid. The deformable solid may be configured to deform so as to substantially cover a sensing surface of the pressure sensing diaphragm to create a barrier between the pressure sensing diaphragm and a measured media. In addition, the deformable solid may fluidly couple the measured media to the pressure sensing diaphragm such that in an instance in which a force is applied to the deformable solid by the measured media the force is transmitted to the pressure sensing diaphragm.

Abstract: Defined herein are immunomodulating Formula (1) compounds wherein R, R0, R1, R2, R3 and W are as defined herein, stereoisomers thereof, and pharmaceutically acceptable salts thereof; and compositions comprising said compounds. The invention also includes methods for treating an inflammatory and/or immunological disease or disorder in an animal by administering a therapeutically effective amount of a Formula (1) compound, stereoisomer thereof, and a pharmaceutically acceptable salt thereof; or use of said compound of Formula (1) to prepare a medicament for treating an inflammatory and/or immunological disease or disorder in an animal.

Abstract: An improved sensor system is provided that monitors and controls a dendritic fluid system. A dendritic fluid system can include artificial components and/or natural components that carry fluid from a source to a destination through a series of paths. The sensor system can include magnetic field sensors, acoustic sensors, encapsulated sensor systems, pressure regulators, and valve controllers to monitor and control the dendritic fluid system. For example, magnetic field sensors, acoustic sensors, and/or pressure regulators can be used to measure the flow of fluid within a dendritic fluid subsystem and/or to detect potential leaks. The encapsulated sensor systems and/or valve controllers can be used to detect fluid levels in a contained system and control valves to adjust the fluid levels in the contained system to a desired level.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for improving operational efficiency within a data center by modeling data center performance and predicting power usage efficiency. An example method receives a state input characterizing a current state of a data center. For each data center setting slate, the state input and the data center setting slate are processed through an ensemble of machine learning models. Each machine learning model is configured to receive and process the state input and the data center setting slate to generate an efficiency score that characterizes a predicted resource efficiency of the data center if the data center settings defined by the data center setting slate are adopted t. The method selects, based on the efficiency scores for the data center setting slates, new values for the data center settings.

Abstract: A system may include a wearable apparatus dimensioned to be worn by a user about an axial region of the user’s body such that, when the wearable apparatus is worn by the user, the user’s field of view into a local environment is substantially free of a view of the wearable apparatus. The system may also include a machine-perception subsystem that is coupled to the wearable apparatus and that gathers information about the local environment by observing the local environment. Additionally, the system may include an experience-analysis subsystem that infers, based on the information about the local environment and information about the user, contextual information about an experience of the user in the local environment. Furthermore, the system may include a non-visual communication subsystem that outputs the contextual information about the experience of the user. Various other apparatuses, systems, and methods are also disclosed.