Patents by Inventor Robert A. Turner

Robert A. Turner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzodioxane inhibitors of leukotriene production
    Patent number: 8946203
    Abstract: The present invention relates to compounds of formula (I): wherein R1 to R3, A, X and n are as defined herein. The compounds of formula (I) are useful as inhibitors of leukotriene A4 hydrolase (LTA4H) and treating LTA4H related disorder. The present invention also relates to pharmaceutical compositions comprising the compounds of formula (I), methods of using these compounds in the treatment of various diseases and disorders, and processes for preparing these compounds.
    Type: Grant
    Filed: March 5, 2013
    Date of Patent: February 3, 2015
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Asitha Abeywardane, Steven Richard Brunette, Michael J. Burke, Suresh R. Kapadia, Thomas Martin Kirrane, Matthew Russell Netherton, Hossein Razavi, Sonia Rodriguez, Anjan Saha, Robert Sibley, Lana Louise Smith-Keenan, Hidenori Takahashi, Michael Robert Turner, Jiang-Ping Wu, Erick Richard Roush Young, Qiang Zhang, Qing Zhang, Renee M. Zindell
  • Method for Multi-Mode, Multi-Load, and Multi-Domain Optimization of a Multi-Channel Near-Field RF Transmitter
    Publication number: 20150028869
    Abstract: The invention relates to a method for optimization of a performance of a multi-channel transmitter including several transmit elements, particularly in a magnetic resonance imaging device.
    Type: Application
    Filed: March 14, 2012
    Publication date: January 29, 2015
    Applicant: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
    Inventors: Mikhail Kozlov, Robert Turner
  • Nucleic acid sample preparation
    Patent number: 8932815
    Abstract: The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples.
    Type: Grant
    Filed: June 20, 2014
    Date of Patent: January 13, 2015
    Assignee: Biological Dynamics, Inc.
    Inventors: Rajaram Krishnan, David J. Charlot, Eugene Tu, James McCanna, Lucas Kumosa, Paul D. Swanson, Robert Turner, Kai Yang, Irina Dobrovolskaya, David Liu, Juan Pablo Hinestrosa Salazar, Juscilene Menezes
  • NUCLEIC ACID SAMPLE PREPARATION
    Publication number: 20150001082
    Abstract: The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples.
    Type: Application
    Filed: September 4, 2014
    Publication date: January 1, 2015
    Inventors: Rajaram KRISHNAN, David CHARLOT, Eugene TU, James MCCANNA, Lucas KUMOSA, Paul D. SWANSON, Robert TURNER, Kai YANG, Irina DOBROVOLSKAYA, David LlU
  • RHO KINASE INHIBITORS
    Publication number: 20140357652
    Abstract: Disclosed are novel substituted 2H-isoquinolin-1-one and 3H-quinazolin-4-one derivatives useful as inhibitors of Rho kinase and for treating a variety of diseases and disorders that are mediated or sustained through the activity of Rho kinase, including cardiovascular diseases, pharmaceutical compositions comprising such compounds, methods for using such compounds and processes for making such compounds.
    Type: Application
    Filed: August 18, 2014
    Publication date: December 4, 2014
    Inventors: Todd Bosanac, John David Ginn, Eugene Richard Hickey, Thomas Martin Kirrane, JR., Weimin Liu, Anthony S. Prokopowicz, Sabine K. Schlyer, Cheng-Kon Shih, Roger John Snow, Michael Robert Turner, Frank Wu, Erick Richard Young
  • NUCLEIC ACID SAMPLE PREPARATION
    Publication number: 20140356877
    Abstract: The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples.
    Type: Application
    Filed: June 20, 2014
    Publication date: December 4, 2014
    Inventors: Rajaram KRISHNAN, David J. CHARLOT, Eugene TU, James MCCANNA, Lucas KUMOSA, Paul D. SWANSON, Robert TURNER, Kai YANG, Irina DOBROVOLSKAYA, David LIU, Juan Pablo HINESTROSA SALAZAR, Juscilene MENEZES
  • Nucleic acid sample preparation
    Patent number: 8877470
    Abstract: The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples.
    Type: Grant
    Filed: March 7, 2014
    Date of Patent: November 4, 2014
    Assignee: Biological Dynamics, Inc.
    Inventors: Rajaram Krishnan, David Charlot, Eugene Tu, James McCanna, Lucas Kumosa, Paul Swanson, Robert Turner, Kai Yang, Irina Dobrovolskaya, David Liu
  • Nucleic acid sample preparation
    Patent number: 8871481
    Abstract: The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples.
    Type: Grant
    Filed: May 6, 2014
    Date of Patent: October 28, 2014
    Assignee: Biological Dynamics, Inc.
    Inventors: Rajaram Krishnan, David Charlot, Eugene Tu, James McCanna, Lucas Kumosa, Paul Swanson, Robert Turner, Kai Yang, Irina Dobrovolskaya, David Liu
  • Medical device and method
    Patent number: 8834478
    Abstract: A device (1) for connecting to an implant (16), comprising: at least two protrusions (8, 9) connectable, in use, to at least one indentation (20) in the implant; and a mechanism for moving the protrusions between a connected and a disconnected position. An implant (16) comprising a body (17) having at least one indentation (20) disposed within the body, wherein, in use, the at least one indentation receives at least two protrusions (8, 9) of a device (1) for connecting to the implant (16) such that the implant is clamped by the device. A method of connecting an implant (16) to a device (1).
    Type: Grant
    Filed: February 9, 2009
    Date of Patent: September 16, 2014
    Assignee: T. J. Smith & Nephew Limited
    Inventors: Nicholas Robert Turner, Matthew Cannell
  • NUCLEIC ACID SAMPLE PREPARATION
    Publication number: 20140248627
    Abstract: The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples.
    Type: Application
    Filed: February 28, 2014
    Publication date: September 4, 2014
    Applicant: Biological Dynamics, Inc.
    Inventors: Rajaram KRISHNAN, David CHARLOT, Eugene TU, James MCCANNA, Lucas KUMOSA, Paul SWANSON, Robert TURNER, Kai YANG, Irina DOBROVOLSKAYA, David Liu
  • NUCLEIC ACID SAMPLE PREPARATION
    Publication number: 20140238860
    Abstract: The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples.
    Type: Application
    Filed: May 6, 2014
    Publication date: August 28, 2014
    Applicant: Biological Dynamics, Inc.
    Inventors: Rajaram KRISHNAN, David Charlot, Eugene Tu, James McCanna, Lucas Kumosa, Paul Swanson, Robert Turner, Kai Yang, Irina Dobrovolskaya, David Liu
  • Nucleic acid sample preparation
    Patent number: 8815555
    Abstract: The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples.
    Type: Grant
    Filed: March 7, 2014
    Date of Patent: August 26, 2014
    Assignee: Biological Dynamics, Inc.
    Inventors: Rajaram Krishnan, David Charlot, Eugene Tu, James McCanna, Lucas Kumosa, Paul Swanson, Robert Turner, Kai Yang, Irina Dobrovolskaya, David Liu
  • Nucleic acid sample preparation
    Patent number: 8815554
    Abstract: The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples.
    Type: Grant
    Filed: February 28, 2014
    Date of Patent: August 26, 2014
    Assignee: Biological Dynamics, Inc.
    Inventors: Rajaram Krishnan, David Charlot, Eugene Tu, James McCanna, Lucas Kumosa, Paul Swanson, Robert Turner, Kai Yang, Irina Dobrovolskaya, David Liu
  • Isoquinolinone Rho kinase inhibitors
    Patent number: 8809326
    Abstract: Disclosed are novel substituted 2H-isoquinolin-1-one and 3H-quinazolin-4-one derivatives useful as inhibitors of Rho kinase and for treating a variety of diseases and disorders that are mediated or sustained through the activity of Rho kinase, including cardiovascular diseases, pharmaceutical compositions comprising such compounds, methods for using such compounds and processes for making such compounds.
    Type: Grant
    Filed: September 18, 2007
    Date of Patent: August 19, 2014
    Assignee: Aerie Pharmaceuticals, Inc.
    Inventors: Todd Bosanac, John David Ginn, Eugene Richard Hickey, Thomas Martin Kirrane, Jr., Weimin Liu, Anthony S. Prokopowicz, Sabine K. Schlyer, Cheng-Kon Shih, Roger John Snow, Michael Robert Turner, Frank Wu, Erick Richard Young
  • NUCLEIC ACID SAMPLE PREPARATION
    Publication number: 20140183042
    Abstract: The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples.
    Type: Application
    Filed: March 7, 2014
    Publication date: July 3, 2014
    Applicant: Biological Dynamics, Inc.
    Inventors: Rajaram KRISHNAN, David CHARLOT, Eugene TU, James MCCANNA, Lucas KUMOSA, Paul SWANSON, Robert TURNER, Kai YANG, Irina DOBROVOLSKAYA, David LIU
  • NUCLEIC ACID SAMPLE PREPARATION
    Publication number: 20140183043
    Abstract: The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples.
    Type: Application
    Filed: March 7, 2014
    Publication date: July 3, 2014
    Applicant: Biological Dynamics, Inc.
    Inventors: Rajaram KRISHNAN, David CHARLOT, Eugene TU, James MCCANNA, Lucas KUMOSA, Paul SWANSON, Robert TURNER, Kai YANG, Irina DOBROVOLSKAYA, David LIU
  • NUCLEIC ACID SAMPLE PREPARATION
    Publication number: 20140174931
    Abstract: The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples.
    Type: Application
    Filed: February 28, 2014
    Publication date: June 26, 2014
    Applicant: Biological Dynamics, Inc.
    Inventors: Rajaram KRISHNAN, David CHARLOT, Eugene TU, James MCCANNA, Lucas KUMOSA, Paul SWANSON, Robert TURNER, Kai YANG, Irina DOBROVOLSKAYA
  • METHODS OF PREPARING AND OPERATING AN MRI MULTI-CHANNEL COIL
    Publication number: 20140152309
    Abstract: A method of preparing a multi-channel coil, in particular for magnetic resonance imaging (MRI) or for a medical treatment device, wherein the multi-channel coil comprises at least two coil rows being axially arranged along a longitudinal direction (z), wherein each of the at least two coil rows comprises a plurality of coil elements being azimuthally distributed relative to the longitudinal direction (z), comprises the steps of a) electro-magnetic decoupling of the coil rows relative to each other, and b) minimizing a reflected power (Pref—row) individually of each of the coil rows. Furthermore, a method of operating a multi-channel coil, in particular for magnetic resonance imaging (MRI) or for a medical treatment device, and a multi-channel coil, which is prepared using to the above method are described.
    Type: Application
    Filed: August 1, 2011
    Publication date: June 5, 2014
    Applicant: Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
    Inventors: Mikhail Kozlov, Robert Turner
  • NUCLEIC ACID SAMPLE PREPARATION
    Publication number: 20140127697
    Abstract: The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples.
    Type: Application
    Filed: October 30, 2013
    Publication date: May 8, 2014
    Applicant: Biological Dynamics, Inc.
    Inventors: Rajaram KRISHNAN, David CHARLOT, Eugene TU, James MCCANNA, Lucas KUMOSA, Paul SWANSON, Robert TURNER, Kai YANG, Irina DOBROVOLSKAYA, David LIU
  • INHIBITORS OF LEUKOTRIENE PRODUCTION
    Publication number: 20140031339
    Abstract: The present invention relates to compounds of formula (I): or a pharmaceutically acceptable salt thereof, wherein A1, A2, L1 and B are as defined herein. The compounds of formula (I) are useful as inhibitors of leukotriene A4 hydrolase (LTA4H) and treating LTA4H related disorders. The present invention also relates to pharmaceutical compositions comprising the compounds of formula (I), methods of using these compounds in the treatment of various diseases and disorders, and processes for preparing these compounds.
    Type: Application
    Filed: July 16, 2013
    Publication date: January 30, 2014
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Asitha ABEYWARDANE, Steven Richard BRUNETTE, Michael Jason BURKE, Thomas Martin KIRRANE, JR., Chuk Chui MAN, Daniel Richard MARSHALL, Anil Kumar PADYANA, Hossein RAZAVI, Robert SIBLEY, Lana Louise SMITH KEENAN, Roger John SNOW, Ronald John SORCEK, Hidenori TAKAHASHI, Steven John TAYLOR, Michael Robert TURNER, Erick Richard Roush YOUNG, Qiang ZHANG, Yunlong ZHANG, Renee M. ZINDELL