Abstract: An example hydraulic tool includes: a fluid reservoir; a pump; an electric motor; a cylinder; a piston; a first trigger button; a second trigger button; and a controller configured to perform operations comprising: receiving a first signal when the first trigger button is triggered, responsively, causing the electric motor to rotate in a first rotational direction, thereby: (i) causing the pump to provide fluid to the cylinder, and (ii) causing the piston to move in a first linear direction, thereafter, receiving a second signal when the second trigger button is triggered, and responsively to the second signal, causing the electric motor to rotate in a second rotational direction opposite the first rotational direction, thereby: (i) opening a fluid path from the cylinder to the fluid reservoir, and (ii) causing the piston to move in a second linear direction opposite the first linear direction.

Abstract: A wellbore anchoring device having an adjustable injection valve is disclosed. The anchoring device can include the adjustable injection valve and a spring. The spring can be positioned adjacent to the adjustable injection valve. The spring can include an initial pressure setting that is adjustable prior to the anchoring device being positioned in a wellbore to adjust a cracking pressure of the adjustable injection valve.

Abstract: Methods of assessing, monitoring and/or predicting clinical disease activity, treatment response, disease progression, and/or active repair for chronic inflammatory disease such as axial spondyloarthritis are provided based on the level and/or pattern of LCN2, LCN2-MMP9 and/or OSM.

Abstract: The present invention relates to formulations comprising dolutegravir or a pharmaceutically acceptable salt thereof, processes for making such formulations, and the use of such formulations in the treatment of HIV infection, in particular in the treatment of HIV infection in pediatric patients.

Abstract: A lock mechanism which can be placed on a shaft, such as a bar or pole, in either a first direction or second direction, is secured to the shaft using two sets of balls which project out of apertures in an inner cylinder to frictionally engage the shaft. The balls are selectively retractable from their projecting position to allow the inner cylinder to slide on and/or be removed from the shaft. Biasing members, such as wavy springs, bias the two sides of the lock mechanism towards one another. In the locked configuration, the balls are forced by inclined surfaces within the two sides to project outwardly from the inner hollow cylinder. The inclined surfaces are aligned with two rows of apertures in the inner hollow cylinder, and they are inclined in opposite directions. Thus, either way the lock mechanism is installed or placed on the shaft, the balls will project out of the apertures in the inner hollow cylinder and will securely engage the shaft.

Abstract: The present invention relates to formulations comprising dolutegravir or a pharmaceutically acceptable salt thereof, abacavir or a pharmaceutically acceptable salt thereof and lamivudine, processes for making such formulations, and the use of such formulations in the treatment of HIV infection, in particular in the treatment of HIV infection in pediatric patients.

Abstract: Methods and systems are provided for an engine housing assembly. In one example, an engine housing assembly comprises an engine housing component, the housing component at least partially defining a first bore for receiving a first shaft and at least partially defining a second bore for receiving a second shaft; and a reinforcement member cast into the housing, the reinforcement member having a lower coefficient of thermal expansion than the housing component, wherein the reinforcement member at least partially surrounds the first and second bores. A method of manufacturing the engine housing assembly is also provided.

Abstract: A lock mechanism which can be placed on a shaft, such as a bar or pole, in either a first direction or second direction, is secured to the shaft using two sets of balls which project out of apertures in an inner cylinder to frictionally engage the shaft. The balls are selectively retractable from their projecting position to allow the inner cylinder to slide on and/or be removed from the shaft. Biasing members, such as wavy springs, bias the two sides of the lock mechanism towards one another. In the locked configuration, the balls are forced by inclined surfaces within the two sides to project outwardly from the inner hollow cylinder. The inclined surfaces are aligned with two rows of apertures in the inner hollow cylinder, and they are inclined in opposite directions. Thus, either way the lock mechanism is installed or placed on the shaft, the balls will project out of the apertures in the inner hollow cylinder and will securely engage the shaft.

Abstract: A lock mechanism which can be placed on a shaft, such as a bar or pole, in either a first direction or second direction, is secured to the shaft using two sets of balls which project out of apertures in an inner cylinder to frictionally engage the shaft. The balls are selectively retractable from their projecting position to allow the inner cylinder to slide on and/or be removed from the shaft. Biasing members, such as wavy springs, bias the two sides of the lock mechanism towards one another. In the locked configuration, the balls are forced by inclined surfaces within the two sides to project outwardly from the inner hollow cylinder. The inclined surfaces are aligned with two rows of apertures in the inner hollow cylinder, and they are inclined in opposite directions. Thus, either way the lock mechanism is installed or placed on the shaft, the balls will project out of the apertures in the inner hollow cylinder and will securely engage the shaft.

Abstract: A lock mechanism which can be placed on a shaft, such as a bar or pole, in either a first direction or second direction, is secured to the shaft using two sets of balls which project out of apertures in an inner cylinder to frictionally engage the shaft. The balls are selectively retractable from their projecting position to allow the inner cylinder to slide on and/or be removed from the shaft. Biasing members, such as wavy springs, bias the two sides of the lock mechanism towards one another. In the locked configuration, the balls are forced by inclined surfaces within the two sides to project outwardly from the inner hollow cylinder. The inclined surfaces are aligned with two rows of apertures in the inner hollow cylinder, and they are inclined in opposite directions. Thus, either way the lock mechanism is installed or placed on the shaft, the balls will project out of the apertures in the inner hollow cylinder and will securely engage the shaft.

Abstract: Method and apparatus for managing data in a distributed data storage system, such as but not limited to a cloud computing environment. In some embodiments, snapshots of a data set are uploaded from a source storage subsystem to a cloud store, along with intervening difference information volumes (DIVs). The DIVs are data structures that identify a set of updated data blocks that have been changed by the source storage subsystem between each successive pair of the snapshots. A reader subsystem requests and uses the latest DIV to request the latest set of changed data blocks from the cloud store, and uses the latest set of changed data blocks to update a previous snapshot to generate a copy of the most recent snapshot. The source and reader subsystems can comprise Internet of Things (IoT) devices, client devices, edge computing devices, etc. from different vendors and which utilize different protocols.

Abstract: An inventory management and purchase order system that provides flexible calculation of reorder quantities, based on bounded time interval sales trends, in which multiple such intervals may be configured (compounded) on a per-SKU basis.

Abstract: Systems and methods for generating a graphical representation for and displaying order performance metrics for one or more user orders of one or more market instruments. A graphical representation of the order performance metrics can be aligned with a graphical representation of market data relating to prices and volume of user orders, market orders, user order executions, and market trades. The order performance metrics can be displayed as one or more performance bars or ribbons divided into segments, which can be assigned a color based on a user order's performance with respect to a market benchmark. The graphical representations can be displayed using a display device.

Abstract: A method of aligning reference frames for an augmented reality display is provided. The method comprises receiving three or more target images positioned at predefined physical reference points in a specified physical space, wherein the physical reference points are part of a reference frame of the physical space. Distances between the physical reference points of the target images are calculated and compared with distances between virtual reference points comprising a reference frame of a three-dimensional virtual model to create a number of distance comparisons. The physical reference points are correlated with virtual reference points according to the distance comparisons. The reference frame of the physical space is then aligned with the reference frame of the three-dimensional virtual model according to the correlation of the physical reference points and virtual reference points.

Abstract: Method and apparatus for managing data in a distributed data storage system, such as but not limited to a cloud computing environment. In some embodiments, snapshots of a data set are uploaded from a source storage subsystem to a cloud store, along with intervening difference information volumes (DIVs). The DIVs are data structures that identify a set of updated data blocks that have been changed by the source storage subsystem between each successive pair of the snapshots. A reader subsystem requests and uses the latest DIV to request the latest set of changed data blocks from the cloud store, and uses the latest set of changed data blocks to update a previous snapshot to generate a copy of the most recent snapshot. The source and reader subsystems can comprise Internet of Things (IoT) devices, client devices, edge computing devices, etc. from different vendors and which utilize different protocols.

Abstract: A vehicle includes a front modular assembly having at least one front wheel, a steering assembly, a throttle, and a power source. The vehicle may include a rear modular assembly removably couplable to the front modular assembly and having at least one rear wheel, a brake selectively coupled to the at least one rear wheel, and at least one rear light configured to emit light while receiving a power signal, the at least one rear light and the brake being in electrical communication with the power source via a shared electrical connection while the rear modular assembly is coupled to the front modular assembly. The vehicle may include a controller in electrical communication with the power source, the controller being configured to selectively provide the power signal to the brake and the rear light via the shared electrical connection.

Abstract: A method includes identifying, using a controller, a first data error at a first data block stored in page metadata, the first data block having a first block logical ID. The method also includes identifying a second data block having the first block logical ID. The method also includes copying the second data block to the first data block based on the identified second data block.

Abstract: Methods and systems are provided for an engine housing assembly. In one example, an engine housing assembly comprises an engine housing component, the housing component at least partially defining a first bore for receiving a first shaft and at least partially defining a second bore for receiving a second shaft; and a reinforcement member cast into the housing, the reinforcement member having a lower coefficient of thermal expansion than the housing component, wherein the reinforcement member at least partially surrounds the first and second bores. A method of manufacturing the engine housing assembly is also provided.

Abstract: A method includes identifying, using a controller, a first data error at a first data block stored in page metadata, the first data block having a first block logical ID. The method also includes identifying a second data block having the first block logical ID. The method also includes copying the second data block to the first data block based on the identified second data block.

Abstract: Systems and methods for generating a graphical representation for and displaying order performance metrics for one or more user orders of one or more market instruments. A graphical representation of the order performance metrics can be aligned with a graphical representation of market data relating to prices and volume of user orders, market orders, user order executions, and market trades. The order performance metrics can be displayed as one or more performance bars or ribbons divided into segments, which can be assigned a color based on a user order's performance with respect to a market benchmark. The graphical representations can be displayed using a display device.