Abstract: A locking mechanism for a shaft provides secure frictional engagement to the shaft while manually operable to be removed from the shaft. There is a first cylinder allowable to slide freely on the shaft. One or more holes retaining one or more balls allow a projection of the balls into an interior of the first cylinder. A tensioning ring (second cylinder) partially overlaps the first cylinder, retains the balls within the holes, and has at least a portion of the inside diameter increasing in diameter. A biasing mechanism acts against the second cylinder to urge the balls into the first cylinder interior to frictionally engage the shaft. Two release mechanisms movable with the biasing mechanism manually actuated against the bias move the second cylinder to allow the balls to freely move within the holes and the locking mechanism to be slid onto and removed from the shaft.

Abstract: A motorcycle foot peg (10) constructed to help isolate a rider from vibration and impact forces normally transmitted through a solid foot peg. The isolating foot peg is applicable for on and off road use where prolonged vibration or discrete impacts may cause injury. The foot peg has an adaptable rigid mounting platform (11) from which a rigid foot peg supporting shaft (19) projects outward in a cantilevered fashion. The supporting shaft is inserted through an internal aperture (34) and secured to an internal rigid tube (29) of a bushing (27). The bushing filled with a vibration isolating material (32) externally is secured to a receiver (23), which is incorporated into a foot peg platform (22). The foot peg platform (22) is thereby isolated from the supporting shaft (19) and motorcycle frame (12) by vibration damping material (32) with in the bushing (27). This relationship allows for reduction of vibratory forces that would normally be transmitted to the rider through a conventional solid Foot peg platform.

Abstract: A method for protecting page-level metadata in a storage system is provided. The method includes providing in a page table first protection data, receiving a command to read data from a page of the storage system corresponding to the page table, and comparing first protection data to second protection data. If the first protection data is different than the second protection data, then the method includes identifying third protection data in the storage system and comparing the third protection data to the first protection data. If the third protection data is different than the first protection data, then the method includes determining that the page-level metadata is inconsistent.

Abstract: There is described herein methods and peptides for detecting autoantibodies to NOG and/or SOST in a patient sample in order to diagnose of prognosticate Ankylosing Spondylitis in the patient.

Abstract: The present invention relates to a combination comprising AZD5363, or a pharmaceutically acceptable salt thereof, and at least one androgen receptor signalling modulator selected from MDV-3100 (also known as enzalutamide), AZD3514, abiraterone (or an ester prodrug thereof: e.g. abiraterone acetate), and bicalutamide; or a pharmaceutically acceptable salt thereof. Each of these combinations may be useful in the treatment of cancer. The invention also relates to pharmaceutical compositions comprising such combinations, and further relates to methods of treatment comprising the simultaneous, sequential or separate administration of AZD5363, or a pharmaceutically acceptable salt thereof, with at least one androgen receptor signalling modulator as described above, to warm-blooded animal, such as a human for the treatment of cancer. The invention also relates to a kit comprising such combinations.

Abstract: A relay fault detection and correction system includes a signal detector structured to measure primary and secondary signals, and generates a fault output signal if the signals appear to be unterminated due to a relay not connecting the signals to the loads. A cycle circuit is structured to cause a relay controller to cycle a potentially under-performing relay between its states a number of times after the signal detector generates the fault output.

Abstract: A locking mechanism for a shaft provides secure frictional engagement to the shaft while manually operable to be removed from the shaft. There is a first cylinder allowable to slide freely on the shaft. One or more holes retaining one or more balls allow a projection of the balls into an interior of the first cylinder. A tensioning ring (second cylinder) partially overlaps the first cylinder, retains the balls within the holes, and has at least a portion of the inside diameter increasing in diameter. A biasing mechanism acts against the second cylinder to urge the balls into the first cylinder interior to frictionally engage the shaft. Two release mechanisms movable with the biasing mechanism manually actuated against the bias move the second cylinder to allow the balls to freely move within the holes and the locking mechanism to be slid onto and removed from the shaft.

Abstract: A locking mechanism for a shaft provides secure frictional engagement to the shaft while manually operable to be removed from the shaft. There is a first cylinder allowable to slide freely on the shaft. One or more holes retaining one or more balls allow a projection of the balls into an interior of the first cylinder. A tensioning ring (second cylinder) partially overlaps the first cylinder, retains the balls within the holes, and has at least a portion of the inside diameter increasing in diameter. A biasing mechanism acts against the second cylinder to urge the balls into the first cylinder interior to frictionally engage the shaft. Two release mechanisms movable with the biasing mechanism manually actuated against the bias move the second cylinder to allow the balls to freely move within the holes and the locking mechanism to be slid onto and removed from the shaft.

Abstract: There is described herein methods and peptides for detecting autoantibodies to NOG and/or SOST in a patient sample in order to diagnose of prognosticate Ankylosing Spondylitis in the patient.

Abstract: The present invention relates to a combination comprising (5)-4-amino-N-(1-(4-chlorophenyl)-3-hydroxypropyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide, or a pharmaceutically acceptable salt thereof, hereafter “Compound (I)”, and a taxane. Taxanes include established cancer drugs such as docetaxel (Taxotere™) and paclitaxel (Taxol™). Such combinations may be useful in the treatment or prophylaxis of cancer. The invention also relates to a pharmaceutical composition comprising such Compound (I) and a taxane. The invention further relates to a method of treatment comprising the simultaneous, sequential or separate administration of Compound (I) and a taxane, to warm-blooded animal, such as man. The invention also relates to a kit comprising Compound (I) and a taxane, optionally with instructions for use.

Abstract: A method for protecting page-level metadata in a storage system is provided. The method includes providing in a page table first protection data, receiving a command to read data from a page of the storage system corresponding to the page table, and comparing first protection data to second protection data. If the first protection data is different than the second protection data, then the method includes identifying third protection data in the storage system and comparing the third protection data to the first protection data. If the third protection data is different than the first protection data, then the method includes determining that the page-level metadata is inconsistent.

Abstract: A closure assembly to be installed in an opening for a building, said closure assembly comprising a frame for supporting a moveable closure member therewithin, said frame including top, bottom and side members, one of the members including a hollow pocket within the interior of said member and for receiving a spring biased roller assembly upon which a flexible material is accumulated, said flexible material being selected from a blind, a bug screen, a solar screen, or the like, the flexible material being movable between a fully retracted first position whereat the material is contained within the pocket to a fully extended second position whereat the material covers some or all of the opening of the building.

Abstract: A method, apparatus, and point cloud generation system for managing a point cloud. Vertices for a model of an object are identified. The object comprises a plurality of parts. Identifiers for the plurality of parts are associated with points in the point cloud using the vertices for the model of the object.

Abstract: This invention describes novel pyrazole compounds of formula IV: wherein Ring D is a 5-7 membered monocyclic ring or 8-10 membered bicyclic ring selected from aryl, heteroaryl, heterocyclyl or carbocyclyl; Rx and Ry are independently selected from T-R3, or taken together with their intervening atoms to form a fused, unsaturated or partially unsaturated, 5-8 membered ring having 1-3 ring heteroatoms selected from oxygen, sulfur, or nitrogen; and R2, R2?, T, and R3 are as described in the specification. The compounds are useful as protein kinase inhibitors, especially as inhibitors of aurora-2 and GSK-3, for treating diseases such as cancer, diabetes and Alzheimer's disease.

Abstract: A method installing a femtocell device in a radio-telecommunications network, wherein the femto-cell device receives from a mobile tele-communication device a set of parameters for connecting the femtocell device to a network access device that provides an access to an Internet Protocol network and connects to a management unit of the radiotelecommunications network, through the Internet Protocol network access, in order to be integrated to the radiotelecommunications network under control of the said first management unit.