Abstract: A method of displaying. The method includes using a system including three-dimensional stereoscopic projection equipment to project an image onto a complex surface of a physical object disposed in an area. The complex surface includes at least one curve or angle. The system also includes a device worn by a user or disposed on a mobile device. The method further includes warping the image based on a geometry of the complex surface, tracking a position and orientation of the user or the mobile device, and further warping the image based on the position and orientation.

Abstract: The present invention relates to a combination comprising (S)-4-amino-N-(1-(4-chlorophenyl)-3-hydroxypropyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide, or a pharmaceutically acceptable salt thereof, hereafter “Compound (I)”, and a taxane. Taxanes include established cancer drugs such as docetaxel (Taxotere™) and paclitaxel (Taxol™). Such combinations may be useful in the treatment or prophylaxis of cancer. The invention also relates to a pharmaceutical composition comprising such Compound (I) and a taxane. The invention further relates to a method of treatment comprising the simultaneous, sequential or separate administration of Compound (I) and a taxane, to warm-blooded animal, such as man. The invention also relates to a kit comprising Compound (I) and a taxane, optionally with instructions for use.

Abstract: Methods and systems are provided for an oil pump mounting structure that provides accessibility and removal of the oil pump without removing a balancer shaft. While periodically servicing or replacing the oil pump may be necessary throughout the lifetime of an engine, it is desirable to allow for easy removal of the oil pump without removing and reassembling other engine components. To provide alignment and a rigid connection between the oil pump and engine frame while allowing for removal of the oil pump without removing other components, dowel bolts with unthreaded, threaded, and dowel portions are used to mount the oil pump to the engine frame.

Abstract: The present invention relates to a combination comprising (5)-4-amino-N-(1-(4-chlorophenyl)-3-hydroxypropyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide, or a pharmaceutically acceptable salt thereof, hereafter “Compound (I)”, and a taxane. Taxanes include established cancer drugs such as docetaxel (Taxotere™) and paclitaxel (Taxol™). Such combinations may be useful in the treatment or prophylaxis of cancer. The invention also relates to a pharmaceutical composition comprising such Compound (I) and a taxane. The invention further relates to a method of treatment comprising the simultaneous, sequential or separate administration of Compound (I) and a taxane, to warm-blooded animal, such as man. The invention also relates to a kit comprising Compound (I) and a taxane, optionally with instructions for use.

Abstract: There is provided herein a method for categorizing a patient having inflammatory bowel disease as being at risk for developing ankylosing spondylitis. The method comprises the use of a patient level of auto-antibodies directed against noggin (NOG) and/or sclerostin (SOST) to determine a risk for the patient developing ankylosing spondylitis. There is also provided methods of monitoring ankylosing spondylitis treatment using these auto-antibodies.

Abstract: Methods, devices, and systems are used for three-dimensional models for three-dimensional makers to indicate engineering requirements. In an example, operations may be effectuated that include displaying a graphical user interface including an object in a three-dimensional (3D) space and receiving first data that includes a link between a flag and a component of the object. The flag may be indicative of an engineering requirement associated with the component of the object. The flag in the 3D space approximate to the component of the object may be displayed based on the received data.

Abstract: The present invention relates to a combination comprising AZD5363, or a pharmaceutically acceptable salt thereof, and at least one androgen receptor signalling modulator selected from MDV-3100 (also known as enzalutamide), AZD3514, abiraterone (or an ester prodrug thereof: e.g. abiraterone acetate), and bicalutamide; or a pharmaceutically acceptable salt thereof. Each of these combinations may be useful in the treatment of cancer. The invention also relates to pharmaceutical compositions comprising such combinations, and further relates to methods of treatment comprising the simultaneous, sequential or separate administration of AZD5363, or a pharmaceutically acceptable salt thereof, with at least one androgen receptor signalling modulator as described above, to warm-blooded animal, such as a human for the treatment of cancer. The invention also relates to a kit comprising such combinations.

Abstract: There is provided herein a method for categorizing a patient having inflammatory bowel disease as being at risk for developing ankylosing spondylitis. The method comprises the use of a patient level of auto-antibodies directed against noggin (NOG) and/or sclerostin (SOST) to determine a risk for the patient developing ankylosing spondylitis. There is also provided methods of monitoring ankylosing spondylitis treatment using these auto-antibodies.

Abstract: The present invention relates to the use of combinations comprising 8-[(1R)-1-(3,5-difluorophenylamino)ethyl]-N,N-dimethyl-2-morpholino-4-oxo-4H-chromene-6-carboxamide or a pharmaceutically acceptable salt thereof and a taxane in the treatment or prophylaxis of cancer; pharmaceutical compositions comprising Compound [I] (or a pharmaceutically acceptable salt thereof) and a taxane; kits comprising Compound [I] or a pharmaceutically acceptable salt thereof and a taxane, optionally with instructions for use; and methods of treatment comprising the simultaneous, sequential or separate administration of Compound [I] or a pharmaceutically acceptable salt thereof and a taxane to warm-blooded animal, such as man.

Abstract: Methods and systems are provided for an oil pump mounting structure that provides accessibility and removal of the oil pump without removing a balancer shaft. While periodically servicing or replacing the oil pump may be necessary throughout the lifetime of an engine, it is desirable to allow for easy removal of the oil pump without removing and reassembling other engine components. To provide alignment and a rigid connection between the oil pump and engine frame while allowing for removal of the oil pump without removing other components, dowel bolts with unthreaded, threaded, and dowel portions are used to mount the oil pump to the engine frame.

Abstract: A relay fault detection and correction system includes a signal detector structured to measure primary and secondary signals, and generates a fault output signal if the signals appear to be unterminated due to a relay not connecting the signals to the loads. A cycle circuit is structured to cause a relay controller to cycle a potentially under-performing relay between its states a number of times after the signal detector generates the fault output.

Abstract: Systems and methods for generating a graphical representation for and displaying order performance metrics for one or more user orders of one or more market instruments. A graphical representation of the order performance metrics can be aligned with a graphical representation of market data relating to prices and volume of user orders, market orders, user order executions, and market trades. The order performance metrics can be displayed as one or more performance bars or ribbons divided into segments, which can be assigned a color based on a user order's performance with respect to a market benchmark. The graphical representations can be displayed using a display device.

Abstract: A network storage appliance is disclosed. The storage appliance includes a port combiner that provides data communication between at least first, second, and third I/O ports; a storage controller that controls storage devices and includes the first I/O port; a server having the second I/O port; and an I/O connector for networking the third I/O port to the port combiner. A single chassis encloses the port combiner, storage controller, and server, and the I/O connector is affixed on the storage appliance. The third I/O port is external to the chassis and is not enclosed therein. In various embodiments, the port combiner comprises a FiberChannel hub comprising a series of loop resiliency circuits, or a FiberChannel, Ethernet, or Infiniband switch. In one embodiment, the port combiner, I/O ports, and server are all comprised in a single blade module for plugging into a backplane of the chassis.

Abstract: A method of displaying. The method includes using a system including three-dimensional stereoscopic projection equipment to project an image onto a complex surface of a physical object disposed in an area. The complex surface includes at least one curve or angle. The system also includes a device worn by a user or disposed on a mobile device. The method further includes warping the image based on a geometry of the complex surface, tracking a position and orientation of the user or the mobile device, and further warping the image based on the position and orientation.

Abstract: A method installing a femtocell device in a radiotelecommunications network, wherein the femtocell device receives from a mobile telecommunication device a set of parameters for connecting the femtocell device to a network access device that provides an access to an Internet Protocol network and connects to a management unit of the radiotelecommunications network, through the Internet Protocol network access, in order to be integrated to the radiotelecommunications network under control of the said first management unit.

Abstract: A motorcycle foot peg (10) constructed to help isolate a rider from vibration and impact forces normally transmitted through a solid foot peg. The isolating foot peg is applicable for on and off road use where prolonged vibration or discrete impacts may cause injury. The foot peg has an adaptable rigid mounting platform (11) from which a rigid foot peg supporting shaft (19) projects outward in a cantilevered fashion. The supporting shaft is inserted through an internal aperture (34) and secured to an internal rigid tube (29) of a bushing (27). The bushing filled with a vibration isolating material (32) externally is secured to a receiver (23), which is incorporated into a foot peg platform (22). The foot peg platform (22) is thereby isolated from the supporting shaft (19) and motorcycle frame (12) by vibration damping material (32) with in the bushing (27). This relationship allows for reduction of vibratory forces that would normally be transmitted to the rider through a conventional solid Foot peg platform.

Abstract: A locking mechanism for a shaft provides secure frictional engagement to the shaft while manually operable to be removed from the shaft. There is a first cylinder allowable to slide freely on the shaft. One or more holes retaining one or more balls allow a projection of the balls into an interior of the first cylinder. A tensioning ring (second cylinder) partially overlaps the first cylinder, retains the balls within the holes, and has at least a portion of the inside diameter increasing in diameter. A biasing mechanism acts against the second cylinder to urge the balls into the first cylinder interior to frictionally engage the shaft. Two release mechanisms movable with the biasing mechanism manually actuated against the bias move the second cylinder to allow the balls to freely move within the holes and the locking mechanism to be slid onto and removed from the shaft.

Abstract: A locking mechanism for a shaft provides secure frictional engagement to the shaft while manually operable to be removed from the shaft. There is a first cylinder allowable to slide freely on the shaft. One or more holes retaining one or more balls allow a projection of the balls into an interior of the first cylinder. A tensioning ring (second cylinder) partially overlaps the first cylinder, retains the balls within the holes, and has at least a portion of the inside diameter increasing in diameter. A biasing mechanism acts against the second cylinder to urge the balls into the first cylinder interior to frictionally engage the shaft. Two release mechanisms movable with the biasing mechanism manually actuated against the bias move the second cylinder to allow the balls to freely move within the holes and the locking mechanism to be slid onto and removed from the shaft.