Abstract: A wireless musical instrument network (400, 500) may comprise one or more wireless link modules (100, 200, 300). In some embodiments a first wireless link module may be adapted to receive a first input audio signal and transmit a first wireless signal having a modulation component based on the first input audio signal. A second wireless link module may be adapted to receive the first wireless signal and a second input audio signal. The second wireless link module may be further adapted to demodulate the first wireless signal to provide a first received audio signal, and combine the first received audio signal and the second input audio signal to provide a combined audio signal.

Abstract: The present invention provides an MHC class II antigen presentation enhancing hybrid polypeptide. The hybrid has an N-terminus comprising the mammalian Ii-key peptide LRMKLPKPPKPVSKMR (SEQ ID NO: 1) and modifications thereof which retain antigen presentation enhancing activity, a C-terminus comprising an antigenic epitope in the form of a polypeptide or peptidomimetic structure which binds to the antigenic peptide binding site of an MHC class II molecule, and an intervening chemical structure covalently linking the N-terminal and C-terminal components. In a particular embodiment, the hybrid peptides of the present invention comprise influenza MHC class II epitopes identified herein as being effective in generating an immune response and provide immunity to the individual.

Abstract: Disclosed is a nucleic acid molecule comprising a first expressible sequence encoding a protein of interest or polypeptide of interest which contains an MHC Class II-presented epitope, or said encoded protein or peptide. In addition, the nucleic acid molecule comprises a second expressible nucleic acid sequence encoding an antigen presentation enhancing hybrid polypeptide, or said encoded protein or peptide.

Abstract: Provided are methods and compositions for treating cancer in humans, the cancer being characterized by expression of Her-2/neu. The methods involve vaccinating a patient with an Ii-Key/MHC class II hybrid construct and thereby stimulating an immune response to the native Her-2/neu protein. The construct may be in the form of an Ii-Key hybrid peptide or a nucleic acid encoding an Ii-Key hybrid peptide. Methods are described wherein the cancer being treated is breast cancer. Also claimed is a pharmaceutical composition comprising an Ii-Key/MHC class II hybrid construct with and without an adjuvant. The adjuvant can include GM-CSF. The Ii-Key hybrid construct includes the LRMK [SEQ ID NO.: 2] residues of Ii-Key protein and an MHC Class II epitope of a protein or portion thereof which is used in the vaccine or a DNA encoding the same hybrid peptide.

Abstract: A payment card processing system and method is provided that allows an account holder to upgrade a private label card to a dual card. The dual card may be used for both private label transactions and bankcard transactions. Methods for upgrading to the dual card account include selecting a private label account having associated monetary and non-monetary data and maintained on a first processing platform for upgrade to a dual card account, creating the dual card account on a second processing platform, transferring the non-monetary data associated with the private label account from the first processing platform to the second processing platform for association with the dual card account, and initiating a trailing activity process to identify monetary and non-monetary activity associated with the private label account and update a cross reference table to associate the trailing activity with the dual card account.

Abstract: The present invention relates to a digital offset phase-locked loop (DOPLL), which may have advantages of size, simplicity, performance, design portability, or any combination thereof, compared to analog-based phase-locked loops (PLLs). The DOPLL may include a digital controlled oscillator (DCO), which provides a controllable frequency output signal based on a digital control signal, a radio frequency (RF) mixer circuit, which provides a reduced-frequency feedback signal based on the controllable frequency output signal without reducing loop gain, a time-to-digital converter (TDC), which provides a digital feedback signal that is a time representation of the reduced-frequency feedback signal, and digital PLL circuitry, which provides the digital control signal based on the digital feedback signal and a digital setpoint signal.

Abstract: Provided are methods and compositions for treating cancer in humans, the cancer being characterized by expression of Her-2/neu. The methods involve vaccinating a patient with an Ii-Key/MHC class II hybrid construct and thereby stimulating an immune response to the native Her-2/neu protein. The construct may be in the form of an Ii-Key hybrid peptide or a nucleic acid encoding an Ii-Key hybrid peptide. Methods are described wherein the cancer being treated is breast cancer. Also claimed is a pharmaceutical composition comprising an Ii-Key/MHC class II hybrid construct with and without an adjuvant. The adjuvant can include GM-CSF. The Ii-Key hybrid construct includes the LRMK residues of Ii-Key protein and an MHC Class II epitope of a protein or portion thereof which is used in the vaccine or a DNA encoding the same hybrid peptide.

Abstract: A fractional-N based Automatic Frequency Control (AFC) system for a mobile terminal is provided. In general, automatic frequency control is implemented in a frequency synthesizer to correct or compensate for a frequency error of an associated reference oscillator. The frequency synthesizer includes a first fractional-N phase-locked loop (FN-PLL) generating a baseband clock signal used by a baseband processor of the mobile terminal, a second FN-PLL generating a receiver local oscillator signal used by a receiver of the mobile terminal to downconvert a received radio frequency signal to a desired frequency, and a translational PLL generating a transmitter local oscillator signal used by a transmitter of the mobile terminal to provide a radio frequency transmit signal. The automatic frequency control is performed by applying a digital correction value, which is preferably multiplicative, to fractional-N dividers of the first and second FN-PLLs.

Abstract: A method, apparatus and computer program product for providing extensible code visualization are presented. Program code is received. A model is generated relating to the program code. The model is mapped to a user interface (UI) to produce a UI reflecting the program code. Changes made to the program code are reflected in the UI and changes made to the UI are reflected in the program code via the model.

Abstract: Provided are methods and compositions for treating cancer in humans, the cancer being characterized by expression of Her-2/neu. The methods involve vaccinating a patient with an Ii-Key/MHC class II hybrid construct and thereby stimulating an immune response to the native Her-2/neu protein. The construct may be in the form of an Ii-Key hybrid peptide or a nucleic acid encoding an Ii-Key hybrid peptide. Methods are described wherein the cancer being treated is breast cancer. Also claimed is a pharmaceutical composition comprising an Ii-Key/MHC class II hybrid construct with and without an adjuvant. The adjuvant can include GM-CSF. The Ii-Key hybrid construct includes the LRMK (SEQ ID NO: 2) residues of Ii-Key protein and an MHC Class II epitope of a protein or portion thereof which is used in the vaccine or a DNA encoding the same hybrid peptide.

Abstract: A polar transmitter that is configurable as either a closed loop polar transmitter or an open loop polar transmitter is provided. In general, the polar transmitter is configured as an open loop polar transmitter when operating at an output power level less than a predetermined threshold and as a closed loop polar transmitter when operating at an output power greater than the predetermined threshold.

Abstract: A linearization system is provided for a Fractional-N Offset Phase Locked Loop (FN-OPLL) in a frequency or phase modulation system. In general, the linearization system processes a modulation signal to provide a linearized modulation signal to a fractional-N divider in a reference path of the FN-OPLL such that a frequency or phase modulation component at the output of the FN-OPLL is substantially linear with respect to the modulation signal.

Abstract: A system and method are provided for switching from one phase-locked loop feedback source to another in a radio frequency (RF) transmitter. The RF transmitter includes a phase-locked loop (PLL) that provides a phase-modulated RF input signal and power amplifier circuitry that amplifies the RF input signal to provide an RF output signal. The PLL includes switching circuitry that couples a feedback path of the PLL to an output of the PLL for open loop operation and couples the feedback path of the PLL to an output of the power amplifier circuitry for closed loop operation. Prior to switching the feedback path from the output of the PLL to the output of the power amplifier circuitry, time alignment circuitry operates to time-align feedback signals from the outputs of the PLL and the power amplifier circuitry such that switching from open loop operation to closed loop operation causes minimal phase disturbance.

Abstract: Disclosed is a method for increasing vaccine potency whereby a subject's immune system is first primed with an Ii-Key hybrid peptide construct before the subject subsequently receives a vaccine for a pathogen of interest. The vaccine may be comprised of a protein or portion thereof that is encoded by the genome of the pathogen. The vaccine may also be a DNA vaccine comprised of DNA encoding a protein of the pathogen. The Ii-Key hybrid peptide construct includes the LRMK residues of Ii-Key protein and an MHC Class II epitope of the protein or portion thereof which is used in the vaccine. The Ii-Key construct may be administered in the form of a nucleic acid construct encoding the Ii-Key hybrid peptide. Priming with Ii-Key peptides enhances the immunogenicity of rHA protein and HA and HIV DNA vaccines. Methods are described relating to the use of Ii-Key hybrid constructs in vaccine protocols wherein the pathogen is HIV or Influenza A, including H5N1.

Abstract: An electrical power generation system for providing electrical power to a load is provided. The system includes a plurality of microturbine units, each microturbine unit having a combustion microturbine engine coupled to an electrical generator. The electrical generator includes a means for converting the rotational movement of the turbine engine into electrical power. A single power module electrically is connected to the load and physically separated from the plurality of generators. The power module has a number of components including an enclosure and a plurality of batteries within said enclosure. A plurality of generator controls is located within the enclosure where each of the generator controls is coupled to one of the plurality of generators. The enclosure also includes a plurality of AC power converters with each AC power converters coupled to one of the electrical generators.

Abstract: A system providing a phase or frequency modulated signal is provided. In general, the system includes a phase locked loop (PLL) having a fractional-N divider in a reference path of the PLL operating to divide a reference frequency based on a pre-distorted modulation signal. Pre-distortion circuitry operates to provide the pre-distorted modulation signal by pre-distorting a modulation signal such that a convolution, or cascade, of the pre-distortion and a transfer function of the PLL results in a substantially flat frequency response for a range of modulation rates greater than a bandwidth of the PLL.

Abstract: The training aid of this invention is a comprehensive golf practice aid, designed to be used by any golfer, using any club, at indoor or outdoor practice venues, with or without the aid of an instructor, to learn and improve most aspects of the golf swing. The invention comprises an aiming arm that serves as a reference for learning and correcting player position relative to ball and target. The invention uses a plurality of break-beam type sensors to detect club movement. The device gives sensory cues to assist the user in adjusting and perfecting swing tempo. The device also measures club speed between fixed points, and assists the user in adjusting and perfecting swing speed by providing a visual representation of changes in speed from swing to swing. During the swing, the training aid can produce a high intensity ultra short duration burst of ultraviolet (UV) energy, invisible to the naked eye, which is focused on the hitting area. The UV burst can be selectively triggered by any of the break-beams.

Abstract: UV curable compositions, polymeric photoinitiators and precursors therefor are described.

Abstract: The present invention provides an MHC class II antigen presentation enhancing hybrid polypeptide. The hybrid has an N-terminus comprising the mammalian Ii key peptide LRMKLPKPPKPVSKMR (SEQ ID NO: 1) and modifications thereof which retain antigen presentation enhancing activity, a C-terminus comprising an antigenic epitope in the form of a polypeptide or peptidomimetic structure which binds to the antigenic peptide binding site of an MHC class II molecule, and an intervening chemical structure covalently linking the N-terminal and C-terminal components.

Abstract: UV curable compositions, polymeric photoinitiators and precursors therefor are described.