Patents by Inventor Robert M. Moriarty

Robert M. Moriarty has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190262351
    Abstract: Disclosed are noribogaine compositions comprising a very high level of the 2(R), 4(S), 5(S), 6(S) and 18(R) enantiomer and not more than 0.5 wt % of ibogaine relative to the total amount of noribogaine.
    Type: Application
    Filed: June 3, 2016
    Publication date: August 29, 2019
    Applicant: DemeRx, Inc.
    Inventors: Robert M. Moriarty, Deborah C. Mash
  • Publication number: 20190135855
    Abstract: Synthetic methods for preparing deoxycholic acid and intermediates thereof, high purity synthetic deoxycholic acid, compositions and methods of use are provided. Also, provided are processes for the synthesis of 12-keto or 12-?-hydroxysteroids from ?-9,11-ene, 11-keto or 11-hydroxy-?-steroids. This invention is also directed to novel compounds prepared during the synthesis. This invention is also directed to the synthesis of deoxycholic acid starting from hydrocortisone.
    Type: Application
    Filed: May 25, 2018
    Publication date: May 9, 2019
    Applicant: Kythera Biopharmaceuticals, Inc.
    Inventors: Robert M. Moriarty, Achampeta Rathan Prasad, John Gregory Reid, Roy A. Swaringen, JR.
  • Publication number: 20190127415
    Abstract: Bile acids and related compositions and methods of synthesis and use. More specifically, deoxycholic acid and related compositions, said compositions being free of all moieties of animal origin and free of pyrogenic moieties.
    Type: Application
    Filed: November 6, 2018
    Publication date: May 2, 2019
    Applicant: Kythera Biopharmaceuticals, Inc.
    Inventors: Robert M. Moriarty, Nathaniel E. David, Nadir Ahmeduddin Mahmood
  • Publication number: 20190107543
    Abstract: Disclosed methods for detecting remnant cancer cells in a tissue sample.
    Type: Application
    Filed: October 3, 2018
    Publication date: April 11, 2019
    Applicant: INDICATOR SYSTEMS INTERNATIONAL, INC.
    Inventors: Robert M. MORIARTY, Richard J. PARIZA, David M. WHITE, Gerald F. Swiss
  • Patent number: 10239891
    Abstract: Disclosed are compounds, compositions and methods for detecting remnant cancer cells in a tissue sample.
    Type: Grant
    Filed: May 15, 2017
    Date of Patent: March 26, 2019
    Assignee: Indicator Systems International, Inc.
    Inventors: Gerald F. Swiss, Richard J. Pariza, Robert M. Moriarty
  • Publication number: 20190048037
    Abstract: Synthetic methods for preparing deoxycholic acid and intermediates thereof are provided.
    Type: Application
    Filed: July 31, 2018
    Publication date: February 14, 2019
    Applicant: Kythera Biopharmaceuticals, Inc.
    Inventors: Achampeta Rathan Prasad, Roy A. Swaringen, JR., John Gregory Reid, Robert M. Moriarty, Akhila Kumar Sahoo
  • Patent number: 10144757
    Abstract: Bile acids and related compositions and methods of synthesis and use. More specifically, deoxycholic acid and related compositions, said compositions being free of all moieties of animal origin and free of pyrogenic moieties.
    Type: Grant
    Filed: June 8, 2017
    Date of Patent: December 4, 2018
    Assignee: Kythera Biopharmaceuticals, Inc.
    Inventors: Robert M. Moriarty, Nathaniel E. David, Nadir Ahmeduddin Mahmood
  • Publication number: 20180338987
    Abstract: Bile acids and related compositions and methods of synthesis and use. More specifically, deoxycholic acid and related compositions, said compositions being free of all moieties of animal origin and free of pyrogenic moieties.
    Type: Application
    Filed: May 23, 2018
    Publication date: November 29, 2018
    Applicant: KYTHERA BIOPHARMACEUTICALS, INC.
    Inventors: Robert M. Moriarty, Nathaniel E. David, Nadir Ahmeduddin Mahmood
  • Publication number: 20180327424
    Abstract: Disclosed are compounds, compositions and methods for detecting remnant cancer cells in a tissue sample.
    Type: Application
    Filed: May 15, 2017
    Publication date: November 15, 2018
    Inventors: Gerald F. SWISS, Richard J. PARIZA, Robert M. MORIARTY
  • Publication number: 20180319800
    Abstract: This invention provides novel (1R,4R) 7-oxo-2-azabicyclo[2.2.2]oct-5-ene and derivatives thereof, preferably in substantially enantiomerically enriched forms, intermediates thereto, and processes of their synthesis.
    Type: Application
    Filed: November 13, 2017
    Publication date: November 8, 2018
    Applicant: DemeRx, Inc.
    Inventor: Robert M. Moriarty
  • Patent number: 10053486
    Abstract: Synthetic methods for preparing deoxycholic acid and intermediates thereof are provided.
    Type: Grant
    Filed: April 24, 2015
    Date of Patent: August 21, 2018
    Assignee: Kythera Biopharmaceuticals, Inc.
    Inventors: Achampeta Rathan Prasad, Roy A. Swaringen, Jr., John Gregory Reid, Robert M. Moriarty, Akhila Kumar Sahoo
  • Publication number: 20180221391
    Abstract: Bile acids and related compositions and methods of synthesis and use. More specifically, deoxycholic acid and related compositions, said compositions being free of all moieties of animal origin and free of pyrogenic moieties.
    Type: Application
    Filed: March 29, 2018
    Publication date: August 9, 2018
    Applicant: Kythera Biopharmaceuticals, Inc.
    Inventors: Robert M. Moriarty, Nathaniel E. David, Nadir Ahmeduddin Mahmood
  • Publication number: 20180209986
    Abstract: This invention is directed to methods for the facile and accurate identification of cancer cells in a tissue sample, such as a surgical field. In particular, the compositions and methods employ conjugates comprising pro-fluorescent fluorescein based moieties bound to folic or pteroic acid targeting moiety optionally through a linker. The pro-fluorescent fluorescein based moieties are non-fluorescent but capable of being rendered fluorescent by intracellular processes. The conjugates are employed to detect cancer cells that overexpress folic acid receptors thereby providing for differential accumulation of these conjugates in these cells.
    Type: Application
    Filed: August 31, 2017
    Publication date: July 26, 2018
    Applicant: ISI Life Sciences, Inc.
    Inventors: John FANTE, Theodore HESSLER, III, Robert M. MORIARTY, Richard PARIZA, Gerald F. SWISS, David WHITE, Craig Keshishian
  • Patent number: 10005813
    Abstract: Synthetic methods for preparing deoxycholic acid and intermediates thereof, high purity synthetic deoxycholic acid, compositions and methods of use are provided. Also, provided are processes for the synthesis of 12-keto or 12-?-hydroxysteroids from ?-9,11-ene, 11-keto or 11-hydroxy-?-steroids. This invention is also directed to novel compounds prepared during the synthesis. This invention is also directed to the synthesis of deoxycholic acid starting from hydrocortisone.
    Type: Grant
    Filed: May 23, 2017
    Date of Patent: June 26, 2018
    Assignee: Kythera Biopharmaceuticals, Inc.
    Inventors: Robert M. Moriarty, Achampeta Rathan Prasad, John Gregory Reid, Roy A. Swaringen, Jr.
  • Patent number: 9987291
    Abstract: Bile acids and related compositions and methods of synthesis and use. More specifically, deoxycholic acid and related compositions, said compositions being free of all moieties of animal origin and free of pyrogenic moieties.
    Type: Grant
    Filed: March 28, 2017
    Date of Patent: June 5, 2018
    Assignee: Kythera Biopharmaceuticals, Inc.
    Inventors: Robert M. Moriarty, Nathaniel E. David, Nadir Ahmeduddin Mahmood
  • Publication number: 20180113128
    Abstract: Disclosed are compositions, methods, and kits that are directed to detection of urease expressing bacterial urinary tract infections and, in particular, those associated with the use of urinary catheters.
    Type: Application
    Filed: October 20, 2017
    Publication date: April 26, 2018
    Applicant: ISI Life Sciences, Inc.
    Inventors: Gerald F. SWISS, Robert M. MORIARTY, Richard PARIZA, David WHITE
  • Patent number: 9949986
    Abstract: Bile acids and related compositions and methods of synthesis and use. More specifically, deoxycholic acid and related compositions, said compositions being free of all moieties of animal origin and free of pyrogenic moieties.
    Type: Grant
    Filed: November 11, 2016
    Date of Patent: April 24, 2018
    Assignee: Kythera Biopharmaceuticals, Inc.
    Inventors: Robert M. Moriarty, Nathaniel E. David, Nadir Ahmeduddin Mahmood
  • Patent number: 9926334
    Abstract: Disclosed are compounds, compositions and methods for detecting remnant cancer cells in a tissue sample.
    Type: Grant
    Filed: May 15, 2017
    Date of Patent: March 27, 2018
    Assignee: Indicator Systems International, Inc.
    Inventors: Gerald F. Swiss, Richard J. Pariza, Robert M. Moriarty
  • Publication number: 20180030065
    Abstract: This technology relates to fluorescein conjugates including fluorescein conjugates of polymers.
    Type: Application
    Filed: January 27, 2016
    Publication date: February 1, 2018
    Applicant: ISI Life Sciences, Inc.
    Inventors: Gerald F. Swiss, Richard Willency, Craig Keshishian, Richard Pariza, Robert M. Moriarty
  • Publication number: 20180015105
    Abstract: The present application is directed to an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid, wherein the composition is maintained at a pH from about 8.1 to about 8.5 such that the composition is stabilized against precipitation. Also disclosed herein, are methods for stabilizing an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid against precipitation, said method comprising maintaining pH of the solution from about 8.1 to about 8.5.
    Type: Application
    Filed: July 28, 2017
    Publication date: January 18, 2018
    Applicant: Kythera Biopharmaceuticals, Inc.
    Inventors: Robert Emil Hodge, Jeffrey Douglas Webster, Robert M. Moriarty