Patents by Inventor Robert M. Moriarty

Robert M. Moriarty has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYNTHETIC BILE ACID COMPOSITIONS AND METHODS
    Publication number: 20160137688
    Abstract: Bile acids and related compositions and methods of synthesis and use. More specifically, deoxycholic acid and related compositions, said compositions being free of all moieties of animal origin and free of pyro-genic moieties.
    Type: Application
    Filed: August 20, 2015
    Publication date: May 19, 2016
    Applicant: KYTHERA BIOPHARMACEUTICALS, INC.
    Inventors: Robert M. Moriarty, Nathaniel E. David, Nadir Ahmeduddin Mahmood
  • PHOSPHATE ESTERS OF NORIBOGAINE
    Publication number: 20160115185
    Abstract: Disclosed herein are phosphate esters of noribogaine and dihydronoribogaine, and esters and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising such compounds, and the methods of their use, including in the treatment of addiction and/or pain.
    Type: Application
    Filed: May 29, 2015
    Publication date: April 28, 2016
    Applicant: DEMERX, INC.
    Inventors: Richard D. Gless, JR., Robert M. Moriarty
  • INDOLE AND BENZOFURAN FUSED ISOQUINUCLIDENE DERIVATIVES AND PROCESSES FOR PREPARING THEM
    Publication number: 20160024075
    Abstract: Provided herein are indole and benzofuran fused isoquinuclidene derivatives. Also provided herein are processes, preferably enantioselective processes, for preparing such derivatives including processes for preparing (?) and (+) noribogaine or a salt thereof, in substantially enantiomerically pure forms.
    Type: Application
    Filed: October 2, 2015
    Publication date: January 28, 2016
    Inventor: Robert M. Moriarty
  • SYNTHETIC BILE ACID COMPOSITIONS AND METHODS
    Publication number: 20160022700
    Abstract: Bile acids and related compositions and methods of synthesis and use. More specifically, deoxycholic acid and related compositions, said compositions being free of all moieties of animal origin and free of pyrogenic moieties.
    Type: Application
    Filed: June 5, 2015
    Publication date: January 28, 2016
    Applicant: KYTHERA BIOPHARMACEUTICALS, INC.
    Inventors: Robert M. Moriarty, Nathaniel E. David, Nadir Ahmeduddin Mahmood
  • HALOGENATED INDOLE AND BENZOFURAN DERIVATIVES OF ISOQUINUCLIDENE AND PROCESSES FOR PREPARING THEM
    Publication number: 20150368255
    Abstract: Provided herein are halogenated indole and benzofuran derivatives of isoquinuclidene and intermediates thereto, and processes, preferably enantioselective processes, for preparing such derivatives including processes for preparing (?) and (+) noribogaine, in substantially enantiomerically pure forms.
    Type: Application
    Filed: June 16, 2015
    Publication date: December 24, 2015
    Inventors: Robert M. Moriarty, Mark Kinch
  • SUBSTITUTED NORIBOGAINE
    Publication number: 20150361080
    Abstract: This invention relates noribogaine derivatives, compositions and methods of use thereof.
    Type: Application
    Filed: May 21, 2015
    Publication date: December 17, 2015
    Applicant: DemeRx, Inc.
    Inventors: Deborah C. Mash, Richard D. Gless, JR., Robert M. Moriarty
  • SUBSTITUTED NORIBOGAINE
    Publication number: 20150329536
    Abstract: This invention relates noribogaine derivatives, compositions and methods of use thereof.
    Type: Application
    Filed: December 20, 2012
    Publication date: November 19, 2015
    Inventors: Deborah C. Mash, Richard D. Gless, Robert M. Moriarty
  • PREPARATION OF BILE ACIDS AND INTERMEDIATES THEREOF
    Publication number: 20150299245
    Abstract: Synthetic methods for preparing deoxycholic acid and intermediates thereof are provided.
    Type: Application
    Filed: April 24, 2015
    Publication date: October 22, 2015
    Applicant: KYTHERA BIOPHARMACEUTICALS, INC.
    Inventors: Achampeta Rathan Prasad, Roy A. Swaringen,, JR., John Gregory Reid, Robert M. Moriarty, Akhila Kumar Sahoo
  • Preparation of bile acids and intermediates thereof
    Patent number: 9150607
    Abstract: Synthetic methods for preparing deoxycholic acid and intermediates thereof are provided.
    Type: Grant
    Filed: December 28, 2012
    Date of Patent: October 6, 2015
    Assignee: KYTHERA BIOPHARMACEUTICALS, INC.
    Inventors: Achampeta Rathan Prasad, Roy A. Swaringen, Jr., John Gregory Reid, Robert M. Moriarty, Akhila Kumar Sahoo
  • Indole and benzofuran fused isoquinuclidene derivatives and processes for preparing them
    Patent number: 9150584
    Abstract: Provided herein are indole and benzofuran fused isoquinuclidene derivatives. Also provided herein are processes, preferably enantioselective processes, for preparing such derivatives including processes for preparing (?) and (+) noribogaine or a salt thereof, in substantially enantiomerically pure forms.
    Type: Grant
    Filed: January 24, 2013
    Date of Patent: October 6, 2015
    Assignee: DEMERX, INC.
    Inventor: Robert M. Moriarty
  • Synthetic bile acid compositions and methods
    Patent number: 9127036
    Abstract: Bile acids and related compositions and methods of synthesis and use. More specifically, deoxycholic acid and related compositions, said compositions being free of all moieties of animal origin and free of pyrogenic moieties.
    Type: Grant
    Filed: August 12, 2010
    Date of Patent: September 8, 2015
    Assignee: KYTHERA BIOPHARMACEUTICALS, INC.
    Inventors: Robert M. Moriarty, Nathaniel E. David, Nadir Ahmeduddin Mahmood
  • Synthetic bile acid compositions and methods
    Patent number: 9050349
    Abstract: Bile acids and related compositions and methods of synthesis and use. More specifically, deoxycholic acid and related compositions, said compositions being free of all moieties of animal origin and free of pyrogenic moieties.
    Type: Grant
    Filed: June 10, 2013
    Date of Patent: June 9, 2015
    Assignee: KYTHERA BIOPHARMACEUTICALS, INC.
    Inventors: Robert M. Moriarty, Nathaniel E. David, Nadir Ahmeduddin Mahmood
  • Phosphate esters of noribogaine
    Patent number: 9051343
    Abstract: Disclosed herein are phosphate esters of noribogaine and dihydronoribogaine, and esters and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising such compounds, and the methods of their use, including in the treatment of addiction and/or pain.
    Type: Grant
    Filed: December 7, 2012
    Date of Patent: June 9, 2015
    Assignee: DEMERX, INC.
    Inventors: Richard D. Gless, Jr., Robert M. Moriarty
  • Substituted noribogaine
    Patent number: 9045481
    Abstract: This invention relates noribogaine derivatives, compositions and methods of use thereof.
    Type: Grant
    Filed: January 29, 2013
    Date of Patent: June 2, 2015
    Assignee: DEMERX, INC.
    Inventors: Deborah C. Mash, Richard D. Gless, Jr., Robert M. Moriarty
  • METHODS FOR THE PURIFICATION OF DEOXYCHOLIC ACID
    Publication number: 20150141679
    Abstract: Synthetic methods for preparing deoxycholic acid and intermediates thereof, high purity synthetic deoxycholic acid, compositions and methods of use are provided. Also, provided are processes for the synthesis of 12-keto or 12-?-hydroxysteroids from ?-9,11-ene, 11-keto or 11-hydroxy-?-steroids. This inversion is also directed to novel compounds prepared during the synthesis. This invention is also directed to the synthesis of deoxycholic acid starting from hydrocortisone.
    Type: Application
    Filed: November 4, 2014
    Publication date: May 21, 2015
    Applicant: Kythera Biopharmaceuticals, Inc.
    Inventors: Robert M. Moriarty, Achampeta Rathan Prasad, John Gregory Reid, Roy A. Swaringen, JR.
  • METHODS AND COMPOSITIONS FOR PREPARING NORIBOGAINE FROM VOACANGINE
    Publication number: 20150133655
    Abstract: Disclosed are methods and compositions for preparing and purifying the non-addictive alkaloid noribogaine.
    Type: Application
    Filed: October 14, 2014
    Publication date: May 14, 2015
    Applicant: DEMERX, INC.
    Inventors: Deborah C. Mash, Robert M. Moriarty, Richard D. Gless, JR.
  • SYNTHETIC BILE ACID COMPOSITIONS AND METHODS
    Publication number: 20150094261
    Abstract: Bile acids and related compositions and methods of synthesis and use. More specifically, deoxycholic acid and related compositions, said compositions being free of all moieties of animal origin and free of pyrogenic moieties.
    Type: Application
    Filed: September 30, 2014
    Publication date: April 2, 2015
    Inventors: Robert M. Moriarty, Nathaniel E. David, Nadir Ahmeduddin Mahmood
  • SYNTHETIC VOACANGINE
    Publication number: 20150094466
    Abstract: Synthetic voacangine, including in substantially enantiomerically enriched forms, and derivatives thereof are provided.
    Type: Application
    Filed: October 3, 2014
    Publication date: April 2, 2015
    Applicant: DemeRx, Inc.
    Inventor: Robert M. Moriarty
  • INFECTION INDICATING MEDICAL DEVICES
    Publication number: 20150037258
    Abstract: Provided herein is an implantable medical device capable of self-reporting microbial growth adjacent the site of the implanted device.
    Type: Application
    Filed: June 23, 2014
    Publication date: February 5, 2015
    Inventors: Gerald F. Swiss, Robert M. Moriarty, Ram W. Sabnis
  • Substituted noribogaine
    Patent number: 8940728
    Abstract: This invention relates noribogaine derivatives, compositions and methods of use thereof.
    Type: Grant
    Filed: January 2, 2013
    Date of Patent: January 27, 2015
    Assignee: DemeRx, Inc.
    Inventors: Deborah C. Mash, Richard D. Gless, Jr., Robert M. Moriarty