Abstract: Described herein are devices and methods comprising a system for tissue reinforcement, such as stabilization of fascial structures of the pelvic floor in vaginal wall prolapse. The surgical treatment can provide a mechanical support or bridging material for a fascial defect. An implant with four arms, for example two proximal arms and two distal arms, can provide post-surgical adjustability of the graft position, enabling tension free placement of the implant. In addition, a four-point fixation of the implant with apical support can ensure a suitable anatomical repair. Furthermore, instrumentation is disclosed herein, including an introducer device capable of fixing a wide variety of materials, such as mesh arms and suture, to tissue.

Abstract: The present invention relates to a mammalian cell based expression and secretion system and the expression and secretion of recombinant proteins by using secretory signal peptides. The present invention also relates to an expression cassette useful for the secretion of a heterologous gene from a mammalian cell, in particular a CHO cell. The present invention is also directed to a method of secreting a heterologous protein from mammalian cells such as CHO cells.

Abstract: Systems and methods for protecting a series capacitor bank are provided. According to one exemplary embodiment of the invention, there is disclosed a capacitor protection circuit. The capacitor protection circuit may include a capacitor bank, a pilot circuit and a main commutation gap. The pilot circuit and the main commutation gap may be provided in parallel electrical communication with the capacitor bank. Additionally, one or more plasma injectors may be provided in series electrical communication with the pilot circuit. The plasma injectors may be operable to provide partially or completely ionized plasma across the main commutation gap to make conductive the main commutation gap.

Abstract: A resonant radiofrequency (RF) detector assembly comprising a substrate, a coil formed on a front surface of the substrate, and two capacitors, each capacitor having a front plate which is formed on the front surface of the substrate and a rear plate formed on a rear surface of the substrate, the two front plates each being electrically connected to a different end of the coil, and the two rear plates being electrically connected to each other.

Abstract: A medical article 100 is used to repair prolapses of various pelvic organs including vaginal vault prolapse. The medical article 100 can include a first flap 105 comprising a dual density mesh formed of a first and second filament, a second flap 101 comprising a single density mesh formed of the first filament, and a third flap 103 comprising a single density mesh formed of the second filament. The first 105, second 101, and third flap 103 can share a common intersection 107 that can form an arc. The medical article 100 can be formed by knitting a uniform piece of mesh and the arc 107 can be configured to conform to a surface of a pelvic organ. Methods of manufacturing and methods of using the medical article are also disclosed.

Abstract: A computing system with an adaptive input mechanism that facilitates intuitive and powerful user/computer interaction is disclosed. One example embodiment includes a logic subsystem, a display link configured to connect a display subsystem to the logic subsystem, and an adaptive device link configured to operatively couple an adaptive device to the logic subsystem. The embodiment further includes an active desktop to host an active application and present the active application on the display subsystem, the active application having active focus. An active-desktop director may pass non-adaptive-device input to the active application having active focus. The embodiment further includes a hidden desktop to host a hidden application having hidden focus specific to the adaptive device while the active application has active focus on the active desktop. A hidden-desktop director may route adaptive-device input to the hidden application having hidden focus.

Abstract: In the field of canine humeral osteotomy, an osteotomy plate including a proximal plate portion lying substantially in a first plane for application to the humerus. The proximal plate portion has a bottom surface adapted for application to the surface of the humerus, and the proximal plate portion has at least one overlapping hole formed therein. The osteotomy plate also includes a distal plate portion lying substantially in a second plane for application to the humerus. The distal plate portion has a bottom surface adapted for application to the surface of the humerus, and the distal plate portion has at least one overlapping hole formed therein. The osteotomy plate also includes a transition region connecting the proximal plate portion to the distal plate portion.

Abstract: Apparatus for heating a fluid being injected in an injection molding system, the apparatus comprising a mold having a cavity, a fluid flow distribution manifold, a fluid flow channel body, a coiled heater tube comprised of a thermally conductive wall, a heater device disposed within the coiled tube; the coiled tube having an upstream, downstream and intermediate coiled portions, the upstream and downstream coiled portions of the coiled tube being selectively movable away from each other along the coil axis to cause the intermediate coiled portion of the coiled tube to stretch or extend in coil axial length.

Abstract: Platforms for laptop computers can include one or more cooling features. In some arrangements, a platform includes a support body that has upper and lower panels that at least partially define an interior cavity. A ventilation plate can be disposed in the upper surface of the support body, and can have a plurality of ventilation holes that are in fluid communication with the interior cavity. In some arrangements, the upper panel is angled relative to the lower panel.

Abstract: Apparatus for heating a fluid being injected in an injection molding system, the apparatus comprising a mold having a cavity, a fluid flow distribution manifold, a fluid flow channel body, a coiled heater tube comprised of a thermally conductive wall, a heater device disposed within the coiled tube; the coiled tube having an upstream, downstream and intermediate coiled portions, the upstream and downstream coiled portions of the coiled tube being selectively movable away from each other along the coil axis to cause the intermediate coiled portion of the coiled tube to stretch or extend in coil axial length.

Abstract: A cable termination system and method of assembly is provided that clamps strength members of the cable after they have been wrapped around a winding member. The clamping force required is therefore reduced by the capstan effect of the winding member. The winding member is preferably a torus that encircles the cable, and the system may comprise a number of progressively larger tori arranged in sequence along the cable to provide sufficient room for wrapping all of the strength members around them.

Abstract: A computer program that can be installed on a web server to assemble web pages that can be accessed over the Internet by password to prepare financial planning reports for a client. The program takes gross income, subtracts income taxes, subtracts all money put into savings programs, and whatever is left is what the client spends in a given year or month. It further itemizes and subtracts the monthly payments for debt service since these items will be fully amortized or paid off at some point in the future and should not be included in baseline living expenses that will continue through a person's lifetime. The balance left after these calculations are completed represents the individual's current annual living expenses or standard of living that needs to be sustained throughout their lifetime with adjustments for inflation.

Abstract: A computer program that can be installed on a web server to assemble web pages that can be accessed over the Internet by password to prepare financial planning reports for a client. The program takes gross income, subtracts income taxes, subtracts all money put into savings programs, and whatever is left is what the client spends in a given year or month. It further itemizes and subtracts the monthly payments for debt service since these items will be fully amortized or paid off at some point in the future and should not be included in baseline living expenses that will continue through a person's lifetime. The balance left after these calculations are completed represents the individual's current annual living expenses or standard of living that needs to be sustained throughout their lifetime with adjustments for inflation.

Abstract: A TPO bone plate with an offset longitudinal axis has a bone-contacting bottom side and a top side. Sets of overlapping holes communicate through the plate from the top to the bottom side. The overlapping holes have multifaceted surfaces such as a threaded surface or a coaxial series of annular grooves. The sets of overlapping holes are adapted to receive a bone screw with a head and a bone-engaging thread.

Abstract: Methods, computer programs, and apparatus for applying a layer of cushion gum to a tire casing in preparation for the retreading of the tire casing, the steps of the methods including selecting one of a plurality recipes for applying cushion gum based on one of a size, model and shape of the tire casing; pressurizing the tire casing to a predetermined pressure based on the recipe; crushing the tire casing by an extruder head a predetermined percentage of the tire casing radius or a predetermined distance, the predetermined percentage based on the recipe; and extruding the cushion gum from the extruder head. The extruder head may be translatable by way of a screw drive.

Abstract: According to one embodiment, a quantum information system includes a source of time dependent entangled photons and an indicating unit. The indicating unit indicates the entangled state of the entangled photons based on the emission time of one or more of the entangled photons.

Abstract: Methods, apparatus and computer programs for correcting a buff of tread from a crown of a tire, the steps of the method including measuring the distance between the tire crown surface and the belt at each of the plurality of locations; calculating a projected distance between the crown surface and the belt at each of the plurality of transverse locations across the crown using proposed buff radii, choosing a new position of the buffing radius origin from the one or more proposed origin positions; and buffing the tread from the tire crown along the arc described by the buff radius having the buffing radius origin at the new position.

Abstract: Methods, apparatus and computer programs for correcting a buff of tread from a crown of a tire, the steps of the method including measuring the distance between the tire crown surface and the belt at each of the plurality of locations; calculating a projected distance between the crown surface and the belt at each of the plurality of transverse locations across the crown using proposed buff radii, choosing a new position of the buffing radius origin from the one or more proposed origin positions on the centerline of the tire; and buffing the tread from the tire crown along the arc described by the buff radius having the buffing radius origin at the new position.

Abstract: Improved apparatus and methods for collecting debris generated during a tire buffing operation on a tire buffing machine, the tire buffing machine having a cutting head cutting surface rotatable about a cutting head axis. The system includes a rotatable shroud being rotatable about a shroud axis, the shroud comprising a side member surrounding a majority of the cutting head cutting surface, a cutting head access window to expose the cutting head for buffing the tire casing, and a vacuum suction port that is adjacent to the cutting head access window. The system may further include a driver to rotate the shroud during buffing, wherein rotating the shroud during buffing aligns the vacuum suction port with the projected path of debris being discharged from the cutting head cutting surface.

Abstract: A securement device, system, and method for use with a medical article. The securement device, system, or method may include a body that has a top surface and a bottom surface. The bottom surface has an adhesive compound thereon. A resilient retainer formed from a soft, tacky elastomeric gel or foam is supported by the bottom surface of the body. The resilient retainer receives and secures a medical device. The medical device is secured to the skin of a patient upon affixing the bottom surface to the patient via the adhesive compound.