Abstract: An all in the head surface cleaning apparatus includes a surface cleaning head having a lower surface having a dirty air inlet. The surface cleaning head may include a brush motor drivingly connected to a movable brushing member having a brush motor axis. The surface cleaning head may include a cyclone comprising a cyclone chamber having a longitudinal cyclone axis. The surface cleaning head may include a suction motor having a first end, a second end and a suction motor axis extending between the first and second ends. The surface cleaning head may include a bleed valve having an inlet end, an outlet end and a body extending between the inlet and outlet ends. The body may have a bleed valve axis. The bleed valve axis may be generally parallel to at least one of the cyclone chamber axis, the suction motor axis and the brush motor axis.

Abstract: A lead anchor includes a body defining a lead lumen having a first opening and a second opening through which a lead can pass. The body further defines a transverse lumen that intersects the lead lumen. An exterior member is disposed around at least a portion of the body. The exterior member is formed of a biocompatible material. A fastener anchors the lead to the body through the transverse lumen by deforming a portion of the lead. The transverse lumen is configured and arranged to receive the fastener. At least at least two suture tabs extend from the exterior member and are configured and arranged for receiving a suture to suture the lead anchor to patient tissue.

Abstract: A biochip for molecular detection and sensing is disclosed. The biochip includes a substrate. The biochip includes a plurality of discrete sites formed on the substrate having a density of greater than five hundred wells per square millimeter. Each discrete site includes sidewalls disposed on the substrate to form a well. Each discrete site includes an electrode disposed at the bottom of the well. In some embodiments, the wells are formed such that cross-talk between the wells is reduced. In some embodiments, the electrodes disposed at the bottom of the wells are organized into groups of electrodes, wherein each group of electrodes shares a common counter electrode. In some embodiments, the electrode disposed at the bottom of the well has a dedicated counter electrode. In some embodiments, surfaces of the sidewalls are silanized such that the surfaces facilitate the forming of a membrane in or adjacent to the well.

Abstract: A motor vehicle airbag system comprises a dual chambered combined head, torso, and knee airbag having a head and torso chamber and a lower extremities chamber in fluid communication with the head and torso chamber. A multidirectional inflator substantially simultaneously inflates both of the head and torso chamber and the lower extremities chamber. The head and torso chamber in the inflated condition acts against a head and a torso of the motor vehicle occupant to generate a restraining force against the occupant to mitigate contact of the occupant head and torso with the upper portion of the instrument panel during the impact event. The lower extremities chamber in the inflated condition acts against the pair of knees of the occupant to mitigate contact of the knees of the occupant with the lower portion of the panel during the impact event.

Abstract: A device for brain stimulation includes a lead body having a longitudinal surface and a distal end. The device further includes at least one ring array. The at least one ring array includes a plurality of split ring electrodes disposed on the distal end of the lead body. Each of the plurality of split ring electrodes includes a stimulating portion and a base portion coupled to the stimulating portion. The split ring electrodes of the at least one ring array are arranged about the circumference of the lead body. At least a portion of the base portion of at least one of the plurality of split ring electrodes is disposed below, and insulated from, at least a portion of the stimulating portion of another of the plurality of split electrodes.

Abstract: This disclosure provides systems and methods for attaching nanopore-detectable tags to nucleotides. The disclosure also provides methods for sequencing nucleic acids using the disclosed tagged nucleotides.

Abstract: The present disclosure provides biochips and methods for making biochips. A biochip can comprise a nanopore in a membrane (e.g., lipid bilayer) adjacent or in proximity to an electrode. Methods are described for forming the membrane and inserting the nanopore into the membrane. The biochips and methods can be used for nucleic acid (e.g., DNA) sequencing. The present disclosure also describes methods for detecting, sorting, and binning molecules (e.g., proteins) using biochips.

Abstract: A device for brain stimulation includes a lead having a longitudinal surface and a distal end. The lead includes a longitudinal rail disposed within the distal end of the lead. The longitudinal rail includes at least two prongs, each prong being configured and arranged to receive at least one segmented electrode. The lead further includes a plurality of segmented electrodes disposed along the longitudinal surface of the lead near the distal end of the lead. Each of the plurality of segmented electrodes is coupled to one of the at least two prongs of the rail.

Abstract: A system for regulating a temperature of a measurement array is disclosed. The system includes a measurement array including a plurality of sensors, wherein the plurality of sensors are integrated onto an integrated circuit die. The system includes a thermal sensor integrated onto the integrated circuit die, wherein the thermal sensor senses a temperature associated with the plurality of sensors. The system further includes a heat pump coupled to the integrated circuit die, wherein the heat pump is controlled by a feedback control circuit including the thermal sensor.

Abstract: Monolithically integrated optical resonators are disclosed. An optical resonator may be a nanopillar optical resonator that is formed directly on a substrate and promotes a helically-propagating cavity mode. The helically-propagating cavity mode may result in significant reflection or, total internal reflection at an interface of the nanopillar optical resonator and the substrate even if refractive indices of the nanopillar optical resonator and the substrate are the same or similar. As a result, strong optical feedback, and thus strong resonance, may be provided in the nanopillar optical resonator.

Abstract: A motor vehicle airbag system comprises a dual chambered combined head, torso, and knee airbag having a head and torso chamber and a lower extremities chamber in fluid communication with the head and torso chamber. A multidirectional inflator substantially simultaneously inflates both of the head and torso chamber and the lower extremities chamber. The head and torso chamber in the inflated condition acts against a head and a torso of the motor vehicle occupant to generate a restraining force against the occupant to mitigate contact of the occupant head and torso with the upper portion of the instrument panel during the impact event. The lower extremities chamber in the inflated condition acts against the pair of knees of the occupant to mitigate contact of the knees of the occupant with the lower portion of the panel during the impact event.

Abstract: An optoelectronic device is disclosed. The optoelectronic device may be employed as a single or multi-channel opto-coupler that electrically isolates one circuit from another circuit. The opto-coupler may include one or more folded leads that establish an enhanced isolation gap. The enhanced isolation gap increases the creepage distance of the opto-coupler and increases operational voltages that can be accommodated by the opto-coupler.

Abstract: This disclosure provides systems and methods for sequencing nucleic acids using nucleotide analogues and translocation of tags from incorporated nucleotide analogues through a nanopore. In aspects, this disclosure is related to composition, method, and system for sequencing a nucleic acid using tag molecules and detection of translocation through a nanopore of tags released from incorporation of the molecule.

Abstract: A device for brain stimulation includes a lead having a longitudinal surface and a distal end. The lead includes a longitudinal rail disposed within the distal end of the lead. The longitudinal rail includes at least two prongs, each prong being configured and arranged to receive at least one segmented electrode. The lead further includes a plurality of segmented electrodes disposed along the longitudinal surface of the lead near the distal end of the lead. Each of the plurality of segmented electrodes is coupled to one of the at least two prongs of the rail.

Abstract: A system for detecting electrical properties of a molecular complex is disclosed. The system includes an electrode electrically coupled to a molecular complex that outputs an electrical signal affected by an electrical property of the molecular complex, wherein the effect of the electrical property of the molecular complex on the electrical signal is characterized by an expected bandwidth. The system further includes an integrating amplifier circuit configured to:receive the electrical signal from the electrode. The integrating amplifier circuit is further configured to selectively amplify and integrate a portion of the electrical signal over time within a predetermined bandwidth, wherein the predetermined bandwidth is selected at least in part based on the expected bandwidth.

Abstract: A device for brain stimulation includes a lead body having a longitudinal surface and a distal end. The device further includes at least one ring array. The at least one ring array includes a plurality of split ring electrodes disposed on the distal end of the lead body. Each of the plurality of split ring electrodes includes a stimulating portion and a base portion coupled to the stimulating portion. The split ring electrodes of the at least one ring array are arranged about the circumference of the lead body. At least a portion of the base portion of at least one of the plurality of split ring electrodes is disposed below, and insulated from, at least a portion of the stimulating portion of another of the plurality of split electrodes.

Abstract: The present disclosure relates generally to connectors such as audio and data connectors and in particular to low profile audio connectors that can be used in place of standard audio and data connectors currently used. The plug connector has a reduced plug length and thickness, an intuitive insertion orientation and a smooth, consistent feel when inserted and extracted from its corresponding receptacle connector. The plug connector may be characterized by a flat tip portion at its distal end, a base portion near its proximal end, a shell coupled at the base portion and a plurality of external contacts.

Abstract: Embodiments of a monolithically integrated optical resonator are disclosed. In one embodiment, the optical resonator is a nanopillar optical resonator that is formed directly on a substrate and promotes a helically-propagating cavity mode. The helically-propagating cavity mode results in significant reflection or, in some embodiments, total internal reflection at an interface of the nanopillar optical resonator and the substrate even if refractive indices of the nanopillar optical resonator and the substrate are the same or similar. As a result, strong optical feedback, and thus strong resonance, is provided in the nanopillar optical resonator.

Abstract: A bone powder filling tool includes a handle connectable to a rotary dental instrument, and a bone powder propelling bit located one end of the handle. The bone powder propelling bit has opposing top end portion and bottom end portion, bone powder transferring grooves spirally extending around the periphery thereof from the top end portion to the bottom end portion, and bone powder propelling threads extending around the periphery thereof at different elevations for rapidly and uniformly propelling bone powder into the space between the sinus floor and the cortical bone to increase the thickness of the cortical bone in favor of the process of the subsequent tooth implanting, helping the doctor in charge of the operation save operating time and physical strength.

Abstract: A device for brain stimulation includes a lead body having a longitudinal surface and a distal end. The device further includes at least one ring array. The at least one ring array includes a plurality of split ring electrodes disposed on the distal end of the lead body. Each of the plurality of split ring electrodes includes a stimulating portion and a base portion coupled to the stimulating portion. The split ring electrodes of the at least one ring array are arranged about the circumference of the lead body. At least a portion of the base portion of at least one of the plurality of split ring electrodes is disposed below, and insulated from, at least a portion of the stimulating portion of another of the plurality of split electrodes.