Patents by Inventor Roger Smith

Roger Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • OMEGA CARBOXYARYL SUBSTITUTED DIPHENYL UREAS AS RAF KINASE INHIBITORS
    Publication number: 20120040986
    Abstract: This invention relates to the use of a group of aryl ureas in treating raf mediated diseases, and pharmaceutical compositions for use in such therapy.
    Type: Application
    Filed: August 11, 2011
    Publication date: February 16, 2012
    Inventors: Bernd RIEDL, Jacques DUMAS, Uday KHIRE, Timothy B. LOWINGER, William J. SCOTT, Roger A. SMITH, Jill E. WOOD, Mary-Katherine MONAHAN, Reina NATERO, Joel RENICK, Robert N. SIBLEY
  • Hydroxy methyl phenyl pyrazolyl urea compounds useful in the treatment of cancer
    Patent number: 8101773
    Abstract: The compound 4-{4-[({3-tert-Butyl-1-[3-(hydroxymethyl)phenyl]-1H-pyrazol-5-yl}carbamoyl)amino]-3-fluorophenoxy}-N-methylpyridine-2-carboxamide and alternative forms thereof (e.g., salts, solvates, hydrates, prodrugs, polymorphs and metabolites); pharmaceutical compositions which contain them; and methods for treating cancer using them.
    Type: Grant
    Filed: December 20, 2007
    Date of Patent: January 24, 2012
    Assignee: Bayer Healthcare LLC
    Inventors: Roger Smith, Dhanapalan Nagarathnam
  • Bicyclic urea derivatives useful in the treatment of cancer and other disorders
    Patent number: 8076488
    Abstract: This invention relates to novel diaryl ureas, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for treating hyper-proliferative and angiogenesis disorders, as a sole agent or in combination with cytotoxic therapies.
    Type: Grant
    Filed: March 1, 2004
    Date of Patent: December 13, 2011
    Assignee: Bayer Healthcare LLC
    Inventors: Jacques Dumas, Stephen Boyer, Sharad Verma, Lila Adnane, Yuanwei Chen, Wendy Lee, Barton Phillips, Roger A. Smith, William J. Scott, Jennifer Burke, Jianqing Chen, Zhi Chen, Jianmei Fan, Karl Miranda, Brian Raudenbush, Aniko Redman, Jianxing Shao, Ning Su, Gan Wang, Lin Yi, Qingming Zhu
  • Power distribution monitoring system and method
    Patent number: 8065099
    Abstract: A power distribution monitoring system includes a number of power line mounted monitors. Each monitor can acquire data regarding the delivery of electrical power in the power line, wirelessly transmit and receive messages, and electromagnetically acquire and store operating electrical power from electrical current flowing in the power line. The system also includes an aggregator that can wirelessly transmit and receive messages and wirelessly output beacon messages. In response to beacon signals wirelessly output by the aggregator, each monitor co-acts with the aggregator to dynamically build a wireless communication network for the wireless communication of the data acquired by the monitor regarding the delivery of electrical power in the power line to the aggregator.
    Type: Grant
    Filed: December 22, 2008
    Date of Patent: November 22, 2011
    Assignee: Tollgrade Communications, Inc.
    Inventors: Jeffrey A. Gibala, Regis J. Nero, Steven P. Day, Matthew G. Cimbala, Roger A. Smith
  • Device, system and method for assembling food orders
    Publication number: 20110253482
    Abstract: A device for assembling orders of food from prepared food items having multiple sides on different sides of the device is disclosed. Also disclosed is a system including the device and a method of assembling orders of food. Each side has a plurality of side receptacles accessible to a worker at the side. Adjacent to the sides is a holding area for holding prepared food items. Preferably the heated holding area has a central portion that is heated.
    Type: Application
    Filed: April 16, 2010
    Publication date: October 20, 2011
    Inventors: James C. Purgatorio, Peter Rivera-Pierola, Roger Smith, Roger Carroll, Henry T. Ewald, Thomas Tapper, Edward P. Bridgman, Paul G. Simmons
  • Methods and Kits for Predicting the Onset of Labour
    Publication number: 20110223622
    Abstract: The present invention relates to methods and kits useful for predicting the time of onset of labour in a pregnant subject. In particular, the invention relates to methods and kits for predicting the time of onset of labour wherein the levels of at least two hormones, selected from estriol, estradiol and progesterone, are determined and a ratio of said levels is calculated, and wherein the time of onset of labour is predicted by comparison of said ratio with a predetermined ratio. The invention further contemplates methods for preventing preterm delivery of an infant/offspring.
    Type: Application
    Filed: July 24, 2009
    Publication date: September 15, 2011
    Inventor: Roger Smith
  • Preparation and use of aryl alkyl acid derivatives for the treatment of obesity
    Patent number: 8013166
    Abstract: This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
    Type: Grant
    Filed: September 5, 2008
    Date of Patent: September 6, 2011
    Assignee: Bayer Healthcare LLC
    Inventors: Roger A. Smith, Ann-Marie Campbell, Philip Coish, Miao Dai, Susan Jenkins, Derek Lowe, Stephen J. O'Connor, Ning Su, Gan Wang, Mingbao Zhang, Lei Zhu
  • UREA COMPOUNDS USEFUL IN THE TREATMENT OF CANCER
    Publication number: 20110195110
    Abstract: Pyrazole urea compounds, pharmaceutical compositions which contain them and methods for treating cancer using them.
    Type: Application
    Filed: December 1, 2006
    Publication date: August 11, 2011
    Inventors: Roger Smith, Holia N. Hatoum-Mokdad, Louis David Cantin, Donald E. Bierer, Wenlang Fu, Dhanapalan Nagarathnam, Gaetan Ladouceur, Yamin Wang, Herbert Ogutu, Scot Wilhelm, Ian Taylor, Sanjeeva Reddy, Richard Gedrich, Christopher Carter, Aaron Schmitt, Xiaomei Zhang
  • NOVEL HETEROCYCLES
    Publication number: 20110172224
    Abstract: The invention relates to novel heterocycles of formula (I) processes for their preparation and their use for preparing medicaments for the treatment or prophylaxis of disorders, especially of hyperproliferative disorders.
    Type: Application
    Filed: August 19, 2005
    Publication date: July 14, 2011
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: Chengzhi Zhang, Jacques Dumas, Qingming Zhu, Roger Smith, Qingjie Liu, Sharad Verma, Jason Duquette, Qian Zhao, Dongping Fan, Georgiy Bondar, Philip Coish
  • Preparation and use of aryl alkyl acid derivatives for the treatment of obesity
    Patent number: 7968576
    Abstract: This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
    Type: Grant
    Filed: September 8, 2008
    Date of Patent: June 28, 2011
    Inventors: Roger A. Smith, Ann-Marie Campbell, Philip Coish, Miao Dai, Susan Jenkins, Derek Lowe, Stephen J. O'Connor, Ning Su, Gan Wang, Mingbao Zhang, Lei Zhu
  • Substituted Pyrazolyl Urea Derivatives Useful In The Treatment Of Cancer
    Publication number: 20110136809
    Abstract: The present invention relates to compounds of formula (I), pharmaceutical compositions which contain them and methods for treating cancer using compounds of formula (I).
    Type: Application
    Filed: November 8, 2010
    Publication date: June 9, 2011
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: Wendy LEE, Gaetan LADOUCEUR, Jacques DUMAS, Roger SMITH, Shihong YING, Gan WANG, Zhi CHEN, Qingjie LIU, Holia Hatoum MOKDAD
  • PREPARATION AND USE OF BIPHENYL-4-YL-CARBONYLAMINO ACID DERIVATIVES FOR THE TREATMENT OF OBESITY
    Publication number: 20110118302
    Abstract: This invention relates to certain biphenyl-4-yl carbonylamino acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
    Type: Application
    Filed: July 14, 2010
    Publication date: May 19, 2011
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: Roger Smith, Stephen J. O'Connor, Philip Coish, Derek Lowe, Roger B. Clark, Jeffrey Stebbins, Ann-Marie Campbell, Christiana Akuche, Tatiana Shelekhin
  • Inhibition of RAF kinase using quinolyl, isoquinolyl or pyridyl ureas
    Patent number: 7928239
    Abstract: This invention relates to the use of a group of aryl ureas in treating raf mediated diseases, and pharmaceutical compositions in such therapy.
    Type: Grant
    Filed: February 7, 2001
    Date of Patent: April 19, 2011
    Assignee: Bayer Healthcare LLC
    Inventors: Jacques Dumas, Bernd Riedl, Uday Khire, Jill E. Wood, Robert N. Sibley, Mary-Katherine Monahan, Joel Renick, David E. Gunn, Timothy B. Lowinger, William J. Scott, Roger A. Smith
  • 2-oxo-1,3,5-perhydrotriazapine derivatives useful in the treatment of hyper-proliferative, angiogenesis, and inflammatory disorders
    Patent number: 7928227
    Abstract: This invention relates to novel diaryl ureas, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for treating hyper-proliferative and angiogenesis disorders, as a sole agent or in combination with cytotoxic therapies.
    Type: Grant
    Filed: March 1, 2004
    Date of Patent: April 19, 2011
    Assignee: Bayer Healthcare LLC
    Inventors: Stephen Boyer, Jacques Dumas, Barton Phillips, William J. Scott, Roger A. Smith, Jianqing Chen, Benjamin Jones, Gan Wang
  • Antifungal compositions and methods
    Publication number: 20110077278
    Abstract: A combination product including a mixture of 3-iodpropynyl-N-n-butylcarbamate (“IPBC”) and 2-n-N-butyl-1,2-benzisothiazolin-3-one (“BBIT) for use as a fungicide and growth inhibitor in industrial applications. Combination products of the present invention are effective for inhibiting the growth of microorganisms, and exhibit a synergistic antifungal effect against fungi such as, for example, Aspergillus niger, Penicillium funiculosum, Trichoderma virens, Chaetosphaeridium globosum, Penicillium sp., and Caratocystis Pilifera. Methods for using the product in metal working fluids, dry film coatings, in-can preservatives, caulks, sealants leather, wood, rope, cordage, textiles, ink, adhesives and polymeric materials are also described.
    Type: Application
    Filed: September 30, 2009
    Publication date: March 31, 2011
    Inventors: Roger Smith, Kamlesh Gaglani
  • PYRIMIDOTHIENOINDAZOLES
    Publication number: 20110053928
    Abstract: The invention relates to novel pyrimidothienoindazoles of formula (I), processes for their preparation and their use for preparing medicaments for the treatment or prophylaxis of disorders, especially of hyperproliferative disorders.
    Type: Application
    Filed: November 3, 2010
    Publication date: March 3, 2011
    Applicant: Bayer Schering Pharma Aktiengesellschaft
    Inventors: Chengzhi Zhang, Roger Smith, Gan Wang, Sharad Verma, Qingming Zhu
  • ?-carboxyl aryl substituted diphenyl ureas as p38 kinase inhibitors
    Patent number: 7897623
    Abstract: This invention relates to the use of a group of aryl ureas in treating p38 mediated diseases, and pharmaceutical compositions for use in such therapy.
    Type: Grant
    Filed: August 27, 2007
    Date of Patent: March 1, 2011
    Assignee: Bayer Healthcare LLC
    Inventors: Bernd Riedl, Jacques Dumas, Uday R. Khire, Timothy B. Lowinger, William J. Scott, Roger A. Smith, Jill E. Wood, Mary-Katherine Monahan, Reina Natero, Joel Renick, Robert N. Sibley
  • Substituted pyrazolyl urea derivatives useful in the treatment of cancer
    Patent number: 7838524
    Abstract: The present invention relates to compounds of formula (I), pharmaceutical compositions which contain them and methods for treating cancer using compounds of formula (I).
    Type: Grant
    Filed: May 2, 2005
    Date of Patent: November 23, 2010
    Assignee: Bayer Healthcare LLC
    Inventors: Wendy Lee, Gaetan Ladouceur, Jacques Dumas, Roger Smith, Shihong Ying, Gan Wang, Zhi Chen, Qingjie Liu, Holia Hatoum Mokdad
  • Autoantibodies utilized as carrier agents for pharmaceutical compounds used in cancer treatment
    Patent number: 7799327
    Abstract: This invention describes a method whereby human autoimmune antibodies are used as carrier compounds to deliver imaging agents and pharmaceutical drugs to the tumor in the human patient. These autoantibodies have the propensity to localize in necrotic areas of tumors but not in healthy normal tissues. By combining various pharmaceutical agents with these carrier proteins it is possible to localize these agents within the necrotic areas of tumors in cancer patients. The carrier proteins may be combined with a variety of imaging agents for detection and diagnosis of tumors, and/or with a variety of radioactive or cytotoxic compounds for cancer treatment.
    Type: Grant
    Filed: December 24, 2003
    Date of Patent: September 21, 2010
    Inventors: Henry John Smith, James Roger Smith
  • PREPARATION AND USE OF BIPHENYL AMINO ACID DERIVATIVES FOR THE TREATMENT OF OBESITY
    Publication number: 20100234307
    Abstract: This invention relates to certain biphenyl amino acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
    Type: Application
    Filed: May 6, 2010
    Publication date: September 16, 2010
    Applicant: Bayer HealthCare LLC
    Inventors: Roger A. Smith, Derek Lowe, Tatiana Shelekhin, Georgiy Bondar, Philip Coish, Stephen J. O'Connor