Patents by Inventor Roger Smith

Roger Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preparation and use of aryl alkyl acid derivatives for the treatment of obesity
    Patent number: 7423156
    Abstract: This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
    Type: Grant
    Filed: January 27, 2006
    Date of Patent: September 9, 2008
    Assignee: Bayer Pharmaceuticals Corporation
    Inventors: Roger Smith, Ann-Marie Campbell, Philip Coish, Miao Dai, Susan Jenkins, Derek Lowe, Stephen O'Connor, Ning Su, Gan Wang, Mingbao Zhang, Lei Zhu
  • Substituted Pyrazolyl Urea Derivatives Useful in the Treatment of Cancer
    Publication number: 20080214545
    Abstract: The present invention relates to compounds of formula (I), pharmaceutical compositions which contain them and methods for treating cancer using compounds of formula (I).
    Type: Application
    Filed: May 2, 2005
    Publication date: September 4, 2008
    Inventors: Wendy Lee, Gaetan Ladouceur, Jacques Dumas, Roger Smith, Shihong Ying, Gan Wang, Zhi Chen, Qingjie Liu, Holia Hatoum Mokdad
  • Inhibition Of Raf Kinase Using Quinolyl, Isoquinolyl Or Pyridyl Ureas
    Publication number: 20080194580
    Abstract: This invention relates to a group of quinolyl, isoquinolyl and pyridyl ureas, their the use in treating raf mediated diseases, and pharmaceutical compositions which contain these ureas for use in such therapy.
    Type: Application
    Filed: October 31, 2007
    Publication date: August 14, 2008
    Inventors: Jacques Dumas, Bernd Riedl, Uday Khire, Robert N. Sibley, Holia Hatoum-Mokdad, Mary-Katherine Monahan, David E. Gunn, Timotthy B. Lowinger, William J. Scott, Roger A. Smith, Jill E. Wood
  • Omega-Carboxyaryl Substituted Diphenyl Ureas As Raf Kinase Inhibitors
    Publication number: 20080153823
    Abstract: This invention relates to the use of a group of aryl ureas in treating raf mediated diseases, and pharmaceutical compositions for use in such therapy.
    Type: Application
    Filed: December 13, 2007
    Publication date: June 26, 2008
    Inventors: Bernd Riedl, Jacques Dumas, Uday Khire, Timothy B. Lowinger, William J. Scott, Roger A. Smith, Jill Wood, Mary-Katherine Monahan, Reina Natero, Joel Renick, Robert Sibley
  • Methods of treating or preventing an infectious disease using an immunogenic conjugate of a gram-negative bacterial autoinducer molecule
    Patent number: 7384639
    Abstract: The present invention relates to an immunogenic conjugate comprising a carrier molecule coupled to an autoinducer of a Gram negative bacteria The immunogenic conjugate, when combined with a pharmaceutically acceptable carrier, forms a suitable vaccine for mammals to prevent infection by the Gram negative bacteria The immunogenic conjugate is also used to raise and subsequently isolate antibodies or binding portions thereof which are capable of recognizing and binding to the autoinducer. The antibodies or binding portions thereof are utilized in a method of treating infections, a method of inhibiting autoinducer activity, and in diagnostic assays which detect the presence of autoinducers or autoinducer antagonists in fluid or tissue samples.
    Type: Grant
    Filed: September 6, 2005
    Date of Patent: June 10, 2008
    Assignee: University of Rochester
    Inventors: Andrew S. Kende, Barbara H. Iglewski, Roger Smith, Richard P. Phipps, James P. Pearson
  • Novel Heterocycles
    Publication number: 20080132497
    Abstract: This invention relates to novel compounds and processes for their preparation, methods of treating diseases, particularly hyperproliferative diseases such as cancer, comprising administering said compounds, and methods of making pharmaceutical compositions for the treatment or prevention of disorders, particularly hyperproliferative diseases such as cancer.
    Type: Application
    Filed: October 14, 2005
    Publication date: June 5, 2008
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: Chengzhi Zhang, Roger Smith, Jason Duquette, Qian Zhao, Jacques Dumas, Georgiy Bondar, Yingfu Li, Dongping Fan
  • Inhibition of raf kinase using quinolyl, isoquinolyl or pyridyl ureas
    Patent number: 7371763
    Abstract: The invention relates to a group of quinolyl, isoquinolyl and pyridyl ureas, their the use in treating raf mediated diseases, and pharmaceutical compositions which contain these ureas for use in such therapy.
    Type: Grant
    Filed: June 22, 2005
    Date of Patent: May 13, 2008
    Assignee: Bayer Pharmaceuticals Corporation
    Inventors: Jacques Dumas, Bernd Riedl, Uday Khire, Robert N. Sibley, Holia Hatoum-Mokdad, Mary-Katherine Monahan, David E. Gunn, Timotthy B. Lowinger, William J. Scott, Roger A. Smith, Jill E. Wood
  • Omega-Carboxyaryl Substituted Diphenyl Ureas As Raf Kinase Inhibitors
    Publication number: 20080108672
    Abstract: This invention relates to the use of a group of aryl ureas in treating raf mediated diseases, and pharmaceutical compositions for use in such therapy.
    Type: Application
    Filed: June 25, 2007
    Publication date: May 8, 2008
    Inventors: Bernd Riedl, Jacques Dumas, Uday Khire, Timothy B. Lowinger, William J. Scott, Roger A. Smith, Jill E. Wood, Mary-Katherine Monahan, Reina Natero, Joel Renick, Robert N. Sibley
  • Global digital measurement device
    Patent number: 7356127
    Abstract: A digital wideband node (DWN) (28, 48) is coupled to a remote terminal (RT) (22, 42) that in turn is coupled to a subscriber's telephone line (26, 46). The DWN (28, 48) is configured to (1) pass a subscriber's telephone number signal directly to the RT (22, 42) whereupon a test path (25, 45) is formed with the subscriber's telephone line (26, 46), (2) pass POTS test signals directly to the RT (22, 42) for testing the subscriber's telephone line (26, 46) via the test path (25, 45) and (3) process wideband test control signals into wideband test signals which are conveyed to the RT (22, 42) for wideband testing of the subscriber's telephone line (26, 46) via the test path (25, 45).
    Type: Grant
    Filed: April 10, 2003
    Date of Patent: April 8, 2008
    Assignee: Tollgrade Communications, Inc.
    Inventors: David J. Peduzzi, Roger A. Smith
  • ?-Carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
    Patent number: 7351834
    Abstract: This invention relates to the use of a group of aryl ureas in treating raf mediated diseases, and pharmaceutical compositions for use in such therapy.
    Type: Grant
    Filed: January 12, 2000
    Date of Patent: April 1, 2008
    Assignee: Bayer Pharmaceuticals Corporation
    Inventors: Bernd Riedl, Jacques Dumas, Uday Khire, Timothy Lowinger, William Scott, Roger A. Smith, Jill E. Wood, Mary-Katherine Monahan, Reina Natero, Joel Renick, Robert Sibley
  • SNAP AND LIFT PACKAGE FOR CONTACT LENS
    Publication number: 20080047848
    Abstract: A contact lens package includes a first housing member and a second housing member pivotably connected to each other. The package also includes a holding mechanism for holding a contact lens and a receiving mechanism for receiving contact lens solution. When the housing members are in a substantially co-planar orientation, the holding mechanism is positioned within the receiving mechanism. When the housing members are in a non-planar orientation, the holding mechanism is removed from the receiving mechanism such that the holding mechanism is pivotable from a closed position, in which the contact lens held in the holding mechanism is inaccessible to a user, toward an open position, in which the contact lens held in the holding mechanism is accessible to the user.
    Type: Application
    Filed: November 20, 2006
    Publication date: February 28, 2008
    Inventors: Michael Tokarski, James Peck, Edward Dzwill, George Brock, James Davis, Roger Smith, Michael Ulrich
  • Inhibition of RAF kinase using aryl and heteroaryl substituted heterocyclic ureas
    Patent number: 7329670
    Abstract: The compounds are aryl and heteroaryl substituted heterocyclic ureas of the formula A—NH—C(O)—NH—B where A is the aryl or hetaryl substituted heterocyclic group and B is an aryl or heteroaryl moiety. The compounds inhibit raf kinase and are useful in the treatment of RAF kinase mediated diseases.
    Type: Grant
    Filed: December 27, 1999
    Date of Patent: February 12, 2008
    Assignee: Bayer Pharmaceuticals Corporation
    Inventors: Jacques Dumas, Uday Khire, Timothy B. Lowinger, Bernard Riedl, William J. Scott, Roger A. Smith, Jill E. Wood, Holia Hatoum-Mokdad, Jeffrey Johnson, Aniko Redman, Robert Sibley
  • Omega-Carboxyaryl Substituted Diphenyl Ureas As Raf Kinease Inhibitors
    Publication number: 20080032979
    Abstract: This invention relates to the use of a group of aryl ureas in treating raf mediated diseases, and pharmaceutical compositions for use in such therapy.
    Type: Application
    Filed: August 27, 2007
    Publication date: February 7, 2008
    Inventors: Bernd Riedl, Jacques Dumas, Uday Khire, Timothy Lowinger, Scott William, Roger Smith, Jill Wood, Mary-Katherine Monahan, Reink Natero, Joel Renick, Robert Sibley
  • Customer relationship management system and method
    Publication number: 20080028021
    Abstract: A software-based customer relationship management system and method.
    Type: Application
    Filed: March 12, 2007
    Publication date: January 31, 2008
    Inventors: John Roberts, Jacob Taylor, Clinton Oram, Andrew Dreisch, Majed Itani, Wayne Pan, Roger Smith, Julian Ostrow, Chris Nojima
  • omega-Carboxy Aryl Substituted Diphenyl Ureas As p38 Kinase Inhibitors
    Publication number: 20080027061
    Abstract: This invention relates to the use of a group of aryl ureas in treating p38 mediated diseases, and pharmaceutical compositions for use in such therapy.
    Type: Application
    Filed: August 27, 2007
    Publication date: January 31, 2008
    Inventors: Bernd Riedl, Jacques Dumas, Uday Khire, Timothy Lowinger, William Scott, Roger Smith, Jill Wood, Mary-Katherine Monahan, Reina Natero, Joel Renick, Robert Sibley
  • INHIBITION OF RAF KINASE USING ARYL AND HETEROARYL SUBSTITUTED HETEROCYCLIC UREAS
    Publication number: 20080009527
    Abstract: Methods of treating tumors mediated by raf kinase, with substituted urea compounds, and such compounds per se,
    Type: Application
    Filed: June 26, 2007
    Publication date: January 10, 2008
    Inventors: Jacques Dumas, Uday Khire, Timothy Lowinger, Bernard Riedl, William Scott, Roger Smith, Jill Wood, Holia Hatoum-Mokdad, Jeffrey Johnson, Aniko Redman, Robert Sibley
  • Novel Pyrimidothienoindazoles
    Publication number: 20070299066
    Abstract: The invention relates to novel pyrimidothienoindazoles of formula (I) processes for their preparation and their use for preparing medicaments for the treatment or prophylaxis of disorders, especially of hyperproliferative disorders.
    Type: Application
    Filed: October 26, 2005
    Publication date: December 27, 2007
    Applicant: Bayer Phamaceuticals Corporation
    Inventors: Chengzhi Zhang, Roger Smith, Gan Wang, Sharad Verma, Qingming Zhu
  • Customer relationship management system and method
    Publication number: 20070283287
    Abstract: A software-based customer relationship management system and method.
    Type: Application
    Filed: May 29, 2007
    Publication date: December 6, 2007
    Inventors: Jacob Taylor, John Roberts, Clinton Oram, Ajay Gupta, Majed Itani, Sadek Baroudi, Roger Smith
  • Preparation and Use of Biphenyl-4-Yl-Carbonylamino Acid Derivatives for the Treatment of Obesity
    Publication number: 20070265298
    Abstract: This invention relates to certain biphenyl-4-yl carbonylamino acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
    Type: Application
    Filed: October 14, 2005
    Publication date: November 15, 2007
    Applicant: Bayer Pharmaceuticals corporation
    Inventors: Roger Smith, Stephen O'Connor, Philip Coish, Derek Lowe, Roger Clark, Jeffrey Stebbins, Ann-Marie Campbell, Christiana Akuche, Tatiana Shelekhin
  • Container with molded digital disk holder
    Publication number: 20070261973
    Abstract: A container with an interior and a neck finish has a recessed pocket on an exterior side of a sidewall for snap fitting a digital disk thereon. Opposing flanges at the periphery of the pocket snap fit the disk in place in a generally vertical orientation.
    Type: Application
    Filed: July 19, 2007
    Publication date: November 15, 2007
    Applicant: Graham Packaging Company L.P.
    Inventors: Robert Harman, John Safian, Roger Smith