Abstract: Methods of treating tumors mediated by raf kinase, with substituted urea compounds, and such compounds per se.

Abstract: The present invention relates to an immunogenic conjugate comprising a carrier molecule coupled to an autoinducer of a Gram negative bacteria The immunogenic conjugate, when combined with a pharmaceutically acceptable carrier, forms a suitable vaccine for mammals to prevent infection by the Gram negative bacteria The immunogenic conjugate is also used to raise and subsequently isolate antibodies or binding portions thereof which are capable of recognizing and binding to the autoinducer. The antibodies or binding portions thereof are utilized in a method of treating infections, a method of inhibiting autoinducer activity, and in diagnostic assays which detect the presence of autoinducers or autoinducer antagonists in fluid or tissue samples. TABLE OF CONTENTS Page 1. FIELD OF THE INVENTION 1 2. BACKGROUND OF THE INVENTION 1 3. SUMMARY OF THE INVENTION 4 4. BRIEF DESCRIPTION OF THE DRAWINGS 7 5. DETAILED DESCRIPTION OF THE INVENTION 7 ??5.

Abstract: A contact lens package has a body with a lens receptacle therein covered by a hinged lid. The lid is offset on the body such that a ledge is formed by the base and an overhang by the lid. The ledge has a plurality of upstanding lugs that insert into mating receptacles formed in the overhang of an adjacent contact lens package, permitting the ganging of packages together for functional and aesthetic reasons.

Abstract: Width enlargement means is described, which is adapted to be attached to a joist end to adapt the latter for use with a joist hanger having a joist receiving socket with diverging side cheeks therein. When attached, the cross section shape of the end of the joist becomes trapezoidal so as to form a wedge. The inclined faces engage the diverging side cheeks of the socket thereby to provide lateral support for the joist end when fitted in the joist receiving socket. One form of enlargement means for a conventional rectangular cross section joist comprises triangular cross section fillets, which are adapted to be fitted to the opposite faces of the end of a the joist. Alternatively it may comprise a wedge shaped member having a central slot into which the end of the joist is fitted. Where the joist has an I-beam cross section, fillets are secured to opposite faces of the central web of the I-beam, or the end of the latter is fitted into a slot in a slotted wedge.

Abstract: A joist hanger is described which comprises one or more open-topped joist receiving sockets, each socket being defined by two side cheeks and a bridge section which joins the lower ends of the two side cheeks, the joist hanger further comprising one or more flanges by which the hanger can be secured to an abutting face and/or upper edge of a wall or beam, characterised in that the two side cheeks diverge from the bridge section to the open top of the joist receiving socket, so that the width of the socket is greater at the top than the bottom, such that a joist will fit snugly in the socket between the two side cheeks in the region of the bridge section but the upper portion of the socket is wider to facilitate entry thereinto of the joist.

Abstract: A communication system having an echo canceller is disclosed. One embodiment of the echo canceller includes an adaptive filter used to provide an estimate of reflected echo which is removed from the send signal. The echo canceller may also include a near-end talker signal detector which may be used to prevent the adaptive filter from adapting when a near-end talker signal is present. The echo canceller may also include a nonlinear processor used to further reduce any residual echo and to preserve background noise. The echo canceller may also include a monitor and control unit which may be used to monitor the filter coefficients and gain of the adaptive filter to maintain stability of the echo canceller, estimate pure delay, detect a tone, and inject a training signal. The echo canceller may also include a nonadaptive filter used to reduce the length of the adaptive filter.

Abstract: This invention relates to the use of a group of aryl ureas in treating raf mediated diseases, and pharmaceutical compositions for use in such therapy.

Abstract: A profiling engine is disclosed. The profiling engine collects information from a variety of sources in real time and stores the information in a profile. The profile may have a number of layers, each layer having a number of categories. The profile is made available for use by applications and services.

Abstract: The invention is directed to the part of the shoe where the bottom of the foot makes contact. This part consists of a resilient material such as foam rubber. This foam is incased with an air tight plastic material, with one way valves. There will be intake valves at the heel and exhaust vents at the toe area. When pressure is applied by the foot to the foam filled bladder, air will be forced out of the one-way valves at the front of the shoe. Then when a step is taken, pressure is removed, and the foam will draw air in the one way valves at the rear of the shoe. With each step and release the air will be circulated.

Abstract: A battery venting system that is useful for cordless power tools. The system can include a cell that may have a sleeve with a plurality of apertures surrounding a peripheral side face of the cell to enhance heat dissipation from the cell. A plurality of cells may be electrically connected to form a cell pack. A carrier includes an upper carrier and a lower carrier to sandwich a plurality of cells that are aligned parallel to each other. The carriers include at least one vent hole that are aligned with a gap formed from adjacent cells to define an elongated fluid flow path. A charger may be provided to receive a housing containing the carrier and may be provided with a fan to direct a flow into the fluid flow path.

Abstract: A vehicle for separating a mixed debris stream is disclosed. The vehicle includes an elongate vehicle frame; a separating assembly configured to contact the mixed debris stream with a fluid stream to separate the mixed debris stream into at least a first debris stream and a second debris stream, and at least one of the first debris stream and the second debris stream includes fluid from the fluid stream; a first conveyor; a second conveyor; and a fluid collection structure configured to receive fluid from at least the separating assembly and the second conveyor, wherein the first conveyor is configured to drain at least some fluid from the first debris stream, to the second conveyor, and the second conveyor includes a non-mesh conveyor belt configured to drain at least some fluid from at least one of the first debris stream and the second debris stream to the fluid collection structure.

Abstract: The invention provides contact lens packages in which removal of the lens is facilitated by providing a means for elevating the lens when the package is opened.

Abstract: Either an endoscopic or open bipolar forceps includes a flexible, generally tubular insulating boot for insulating patient tissue, while not impeding motion of the jaw members. The jaw members are movable from an open to a closed position and the jaw members are connected to a source of electrosurgical energy such that the jaw members are capable of conducting energy through tissue held therebetween to effect a tissue seal. A knife assembly may be included that allows a user to selectively divide tissue upon actuation thereof. The insulating boot may be made from a viscoelastic, elastomeric or flexible material suitable for use with a sterilization process including ethylene oxide.

Abstract: A chainsaw tensioner that includes set of bevel gears. The input gear is connected to a knob to be operated to the user. Torque from the input knob is transferred to an output bevel gear that is connected to a threaded rod. A plate travels about the threaded rod and is mated with the chain guide bar. When the rod is rotated, the plate and the chain guide bar translate linearly to either tighten or loosen the chain around the periphery of the chain guide bar depending on the direction of rotation of the knob.

Abstract: A vehicle for breaking material is disclosed. The vehicle includes: an elongate vehicle frame; a feeder having a feed end portion and a discharge end portion, wherein the feeder is configured to convey the material from the feed end portion to the discharge end portion; and a material breaker supported via the vehicle frame with a feed end portion that is downstream from the discharge end portion of the feeder. The material breaker includes: a platform configured to support the material received from the feeder, at least one breaker element configured to move towards the platform and contact at least a portion of the material received from the feeder and supported by the platform, wherein movement of the at least one breaker element towards the platform is assisted, at least in part, by gravitational forces, and a lifting mechanism configured to move the at least one breaker element away from the platform.

Abstract: A computing hardware and software device called a Meta Mentor Central Processing Unit. The Meta Mentor purpose is to control memory, input/output interfaces, defining the operating system, the scheduling processes and the parsing of individual threads to an array of slave Processing Units that are uniquely connected, thus creating a highly optimized computing core. In effect, the Meta Mentor tells the array of slave processors what to process by controlling all external and internal system input/output and individual processor scheduling.

Abstract: A removable electrode assembly for use in combination with a forceps having opposing end effectors and a handle for effecting movement of the end effectors relative to one another. The electrode assembly includes a housing which is removably engageable with the forceps and a pair of electrodes which are attachable to a distal end of the housing. The electrodes are removably engageable with the end effectors of the forceps such that the electrodes reside in opposing relation relative to one another. The electrode assembly also includes a cover plate which is removably attachable to the housing and at least one stop member for controlling the distance between the opposing electrodes. The stop member is selectively engageable with the electrodes.

Abstract: A bead lock including an insert casing and a bead spacer for providing an air passageway in a vehicle tire to be mounted on a wheel rim on which is located an insert valve and a rim lip for retention of the vehicle tire bead, the insert casing including an insert bead adapted to push against the tire bead and to hold the tire bead firmly against the inner surface of the rim lip, the inner wall of the vehicle tire and the outer surface of the insert casing defining an internal tire space to be pressurized for inflation of the vehicle tire or depressurized for the deflation of the vehicle tire via the insert valve, the tire bead and the insert bead interposed between the internal tire space and the insert valve, the bead spacer extending from the insert bead to an insert valve area corresponding in use to the insert valve location whereby to define at least one air passage for communication of the internal tire space with the insert valve, wherein the bead spacer is made of material sufficiently flexible to sub

Abstract: An ophthalmic lens package includes a pair of shell members that are removably attached to each other and a pair of absorbent members sandwiched therebetween. The shell members are connected to each other by a hinge at one of their ends, and are pivotable relative to each other about the hinge between a closed position, in which the shell members are attached to each other, and an open position.