Abstract: The invention relates to amorphous solid forms and pharmaceutical compositions comprising amorphous lenvatinib besylate (benzene sulfonate), and the processes for their preparation.

Abstract: The invention provides a compound of formula I and a process for preparing a compound of formula I, wherein R is H (Formula Ia) or CH2COCH3 (Formula Ib).

Abstract: The present invention relates to an improved process for the preparation of a compound of formula V or a salt thereof, Formula (V) The present invention also provides a process for the preparation of a compound of formula I, used in the synthesis of the compound of formula V, Formula (I) wherein Formula I is Formula Ia, when R is H wherein Formula I is Formula Ib, when R is CH2COCH3.

Abstract: Certain aspects of the disclosure provide techniques for information retrieval for large datasets. A method comprises receiving input text files and a query for the files; obtaining an index associated with the input text files to process the query, wherein: the index comprises key-value mappings, each key of a respective mapping identifying a voronoi cell of the index, and each value of a respective mapping identifying vector embeddings associated with text files associated with a voronoi cell of the index; creating a query embedding based on the query; identifying a first key-value mapping having a first key associated with a first voronoi cell in the index and corresponding to the query embedding; obtaining a set of vector embeddings associated with the first value; comparing the query embedding to the set of vector embeddings to determine closest vector embeddings; and generating a textual output based on the closest vector embeddings.

Abstract: A computer implemented method for generating a response to a received electronic message. A generative AI is prompted to analyse the electronic message and to generate intent data indicative of an intent associated with the electronic message and data-identifier data indicative of one or more predetermined data identifiers present in the electronic message. The electronic message is analysed to identify and retrieve client data associated with one or more parties associated with the electronic message. The method includes Verifying the retrieved client data includes data corresponding to the generated data-identifier data. If so, query an ERP system with the verified data-identifier data to extract ERP data corresponding to the predetermined data identifiers of which the data-identifier data is indicative, select a response-message template using the intent data, populate the selected response-message template with the ERP data, and present the populated response-message template to a user for approval.

Abstract: Accordingly, the embodiment herein is to provide a method for coordinating tune away event of a Multiple Universal Subscriber Identity Module User Equipment (MUSIM UE) (100), where the MUSIM UE (100) includes a plurality of Subscriber Identity Modules (SIMs) (150). The method includes receiving, by a second SIM (150B) of the MUSIM UE (100), data in a Downlink (DL) message from a network device (200) over an air interface, where the data includes a follow-on indication. Further, the method includes decoding, by the second SIM (150B) of the MUSIM UE (100), the received data. Further, the method includes coordinating, by the second SIM (150B) of the MUSIM UE (100), the tune away event of the MUSIM UE (100) based on the decoding of the received data.

Abstract: The present invention relates to a monolithic tablet composition for oral administration of tofacitinib or a pharmaceutically acceptable salt thereof, without a functional coating.

Abstract: Disclosed is a method for distributing uplink packets between a primary Radio Link Control (RLC) path and a secondary RLC path in a packet duplication configured bearer. The method includes transmitting, by a user equipment (UE), the uplink packets over the primary RLC path and the secondary RLC path as duplicate packets, dynamically receiving, at the UE from a network entity, a deactivation signal via a Medium Access Control (MAC) control element or a Radio Resource Control (RRC) reconfiguration, the deactivation signal indicating deactivation of packet duplication, and discarding, at the UE, one or more non-transmitted duplicate packets from the primary RLC path and the secondary RLC path based on a discard ratio in response to receiving the deactivation signal, the discard ratio being indicative of a packet discarding proportion between the primary RLC path and the secondary RLC path.

Abstract: The present invention relates to a Budesonide formulation with one or more layers comprising organic acid and Budesonide in the same layer.

Abstract: A textbook planner client computer system communicates with an artificial intelligence (AI) based content generation system for the generation of textbooks based on inputs provided by a user. The AI-based content generation system is configured to receive natural language textbook generation request data from the textbook planner client computer system. The textbook generation request includes a natural language request data describing a grade and subject for which the textbook is desired. The received natural language request data is then processed by the AI-based content generation system using an artificial intelligence system having a natural language processing engine that includes a language model and machine learning algorithms. During the textbook generation process, the AI-based content generation system also accesses a curriculum database including curriculum data for one or more educational standards.

Abstract: A text-to-speech engine creates audio output that includes synthesized speech and one or more media content item snippets. The input text is obtained and partitioned into text sets. A track having lyrics that match a part of one of the text sets is identified. The location of the track's audio that contains the lyric is extracted based on forced alignment data. The extracted audio is combined with synthesized speech corresponding to the remainder of the input text to form audio output.

Abstract: A computer-implemented method of generating a synthetic image of a space for lighting design includes obtaining an input image of the space and performing parsing of the input image of the space to detect objects in the input image. The method further includes classifying the objects detected in the input image at least based on relevance to lighting design of the space and relevance to privacy. The method also includes generating a synthetic image of the space from the input image of the space. A first object of the objects in the input image is included in the synthetic image, and a second object of the objects in the input image is left out from the synthetic image. The first object is relevant to the lighting design, and the second object is relevant to privacy.

Abstract: Systems, methods, and storage media provided are useful in a computing environment receiving, modifying, and transforming service level information from database servers and entities in a hosted database environment. Multiple application programming interface (API) calls are made by a database observation system to request information for multiple service level indicators from database servers belonging to multiple different entities. Database observation system receives and aggregates the information for multiple service level indicators from each of the database servers belonging to multiple different entities. The database observation system provides, within a dashboard interface, the aggregated information for each of the multiple service level indicators, individual service level indicator scores, and aggregated service level indicator scores for each of the database servers for each of the multiple entities.

Abstract: The present invention relates to a film-coated swallowable tablet comprising eltrombopag bis(monoethanolamine) and pharmaceutically acceptable excipients comprising calcium silicate as diluent. The invention further relates to the use of said tablet as a medicament, particularly in the treatment of immune thrombocytopenia (ITP), thrombocytopenia in patients with chronic hepatitis C virus (HCV) and severe aplastic anaemia (SAA).

Abstract: The present invention relates to an improved process for the preparation of a compound of formula V or a salt thereof, Formula (V) The present invention also provides a process for the preparation of a compound of formula I, used in the synthesis of the compound of formula V, Formula (I) wherein Formula I is Formula Ia, when R is H wherein Formula I is Formula Ib, when R is CH2COCH3.

Abstract: Systems and methods are provided implementing a configurable API connector.

Abstract: The present invention provides compositions and methods useful for the treatment of narcolepsy, including narcolepsy type 1 and narcolepsy type 2, cataplexy, excessive daytime sleepiness, and the like in a subject in need thereof. In embodiments, the methods comprise administering to the subject an effective amount of Compound A or a pharmaceutically acceptable salt thereof, wherein Compound A or a pharmaceutically acceptable salt thereof is administered orally once or more per day.

Abstract: A system for determining occupancy in an environment is provided. The system includes plurality of sensor bundles, with each bundle including a presence sensor and a motion sensor. The system further includes a controller in communication with each sensor bundle. The controller is configured to designate one of the sensor bundles as presence triggered if persons are present within a field of view of the presence sensor. The controller is further configured to designate one of the sensor bundles as motion triggered if persons are moving within a field of view of the motion sensor. The controller is further configured to determine a triggered bundle count of the sensor bundles which are both presence triggered and motion triggered. The controller is further configured to determine an occupancy count for the environment based upon the triggered bundle count.

Abstract: The present invention relates to a tablet composition comprising Ibrutinib and one ore more pharmaceutically acceptable excipients. The invention further relates to the use of said composition as a medicament, particularly in the treatment of lymphocytic leukaemia (CLL), mantle cell lymphoma (MCL), Waldenström's macroglobulinaemia (WM) and chronic graft versus host disease (cGVHD).

Abstract: The present invention relates to an immediate release tablet composition comprising axitinib form IV characterized by an XRPD pattern comprising the peaks at about 8.9, 12.0, 14.6, 15.2, 15.7, 17.8, 19.1, 20.6, 21.6, 23.2, 24.2, 24.9, 26.1 and 27.5±0.1 degrees 2?, when measured with Cu K?1 radiation and one or more pharmaceutically acceptable excipients, wherein the composition exhibits a dissolution rate between 40% and 70% in 30 minutes when tested in 900 ml 0.01 N hydrochloric acid pH 2.0 at 37° C., 75 rpm in a USP apparatus II.