Abstract: The present invention relates to an immediate release tablet composition comprising axitinib form IV characterized by an XRPD pattern comprising the peaks at about 8.9, 12.0, 14.6, 15.2, 15.7, 17.8, 19.1, 20.6, 21.6, 23.2, 24.2, 24.9, 26.1 and 27.5±0.1 degrees 2?, when measured with Cu K?1 radiation and one or more pharmaceutically acceptable excipients, wherein the composition exhibits a dissolution rate between 40% and 70% in 30 minutes when tested in 900 ml 0.01 N hydrochloric acid pH 2.0 at 37° C., 75 rpm in a USP apparatus II.

Abstract: Methods, systems and computer program products for lockless acquisition of memory for RDMA operations. A contiguous physical memory region is allocated. The contiguous physical memory region is divided into a plurality of preregistered chunks that are assigned to one or more process threads that are associated with an RDMA NIC. When responding to a request from a particular one of the one or more process threads, a buffer carved from the preregistered chunk of the contiguous physical memory region is assigned to the requesting process thread. Since the memory is pre-registered, and since the associations are made at the thread level, there is no need for locks when acquiring a buffer. Furthermore, since the memory is pre-registered, the threads do not incur registration latency. The contiguous physical memory region can be a contiguous HugePage contiguous region from which a plurality of individually allocatable buffers can be assigned to different threads.

Abstract: Novel tools and techniques are provided for detecting and correcting anomalous events in real-time in as users enter data into a general ledger. In various embodiments, a computing system may receive one or more user inputs. The computing system might analyze the one or more user inputs to determine whether there are one or more anomalous transactions associated with the one or more user inputs by obtaining historical information associated with the one or more user inputs and correlating, using one or more machine learning algorithms, the historical information and the one or more user inputs to detect one or more anomalies. Based on the correlation between the historical information and the one or more first user inputs, the computing system might detect at least one anomalous transaction and might generate one or more recommended actions to correct the at least one anomalous transaction.

Abstract: A system and methods are provided for an immersive group lighting interaction. A lighting infrastructure includes a plurality of independently controllable lighting devices. According to an embodiment, users may be granted access to control at least a portion of the lighting infrastructure. Rather than requiring the user to manually control the lighting infrastructure using, for example, the touch screen, a sensor associated with the user's mobile device may track the user. The sensor data may be classified and then mapped to a corresponding control instruction to control the lighting infrastructure. In another embodiment, a computing system receives sensor classifications from multiple users. If a threshold amount of a type of classification is received, the computing system controls a lighting infrastructure according to that type of classification.

Abstract: A system for optimizing telemetry volume generated for an application product includes: a volume calculation service and a configuration service coupled to a client device via a network connection. The volume calculation service receiving identification of a particular event that occurs during execution of the application product by the client and calculating an optimized sampling rate for that event in telemetry produced by the client, the optimized sampling rate calculated based on reducing an overall volume of telemetry while still maintaining tracking of the particular event within the telemetry. The configuration service generating a configuration for the client device, the configuration service configuring the client to use the optimized sampling rate to produce telemetry for the event during execution of the application product by the client device.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for optimizing performance issues. One of the methods includes maintaining, for a plurality of devices at least some of which have different contexts, metric data for an application that executed on each of the plurality of devices; determining, for a metric attribute from a plurality of metric attributes and a subset of the plurality of devices each of which have at least one common context, a potential performance issue for the subset of the plurality of devices using aggregated metric data for the metric attribute; determining, using at least a portion of the aggregated metric data, a portion of a code base or a hardware subcomponent that likely caused the potential performance issue; and providing data for the portion of the code base or the hardware subcomponent that likely caused the potential performance issue.

Abstract: Several new inventions are detailed with this system, method, and device. While at the core, these inventions may ablate tissue by application of a short duration electric field, the therapy waveform used to apply the electric field is novel and optimized to preserve the intra-cellular content possible across different identified tissues. The optimized pulse biases tissue to an electroporation state and then presents a “hammer pulse” which may be along the same polarity or different polarity. This treatment minimizes thermal effects and is being defined as Pulse Field Immunotherapy (PFI). The antigens are left in situ and taken up by antigen-presenting cells in the periphery allowing the immune system to engage. Additional tissue feedback is obtained through an invention that performs measurements on tissue to determine its composition while the applicator is inserted into normal tissue, followed by diseased tissue.

Abstract: The presented invention relates to pharmaceutical composition comprising Bempedoic acid and processes for preparation thereof.

Abstract: Light sources including one or more light emitting diodes (LEDs) comprise: a primary down converter material on the one or more LEDs; and a roughened down converter material on the one or more LEDs. The down converter material may comprise a polycrystalline ceramic plate of a phosphor material. A method of manufacturing a light source comprises: measuring a baseline color point distribution of a baseline light source, and a primary down converter material in the absence of any laser-modified down converter material; preparing a baseline color point distribution graph; identifying one or more sections of the primary down converter material whose corresponding LEDs contribute to deviating from a tuned color point distribution; and applying a roughening laser treatment to prepare one or more sections of roughened down converter material, and thereby prepare a light source having the tuned color point distribution.

Abstract: Light sources including one or more light emitting diodes (LEDs) comprise a down converter material on the one or more LEDs; and a functional material that is laser-patterned on the down converter material. The functional material may be a distributed Bragg reflector (DBR). a dichroic filter (DCF), a ceramic material, or a powdered phosphor layer. The down converter material may comprise a polycrystalline ceramic plate of a phosphor material. A method of manufacturing a light source comprises: patterning a functional material of a light source comprising one or more light emitting diodes and a phosphor material.

Abstract: Systems and methods are provided for recommending media content to users with disabilities. In response to determining that a user has a disability, a type of the disability is determined. A media content item to recommend to the user is determined, among a plurality of media content items, based on the determined type of disability and a favorability factor of the media content item for the determined type of disability. The favorability factor of the media content item corresponds to an ability of a user with the determined type of disability to comprehend the media content item. An identifier of the determined media content item is generated for presentation.

Abstract: The technology disclosed herein enables continuity of a call recording when a recording system restarts. In a particular example, a method includes establishing a recording session between a session recording client and a session recording system. The recording session is associated with a communication session being recorded. The method also includes periodically transmitting requests for counter values from the session recording system. The counter value indicates a number of times the session recording system has restarted. The method further includes receiving a first counter value of the counter values from the session recording system and receiving subsequent counter values of the counter values from the session recording system after receiving the first counter value. In response to determining that one of the subsequent counter values does not match the first counter value, the method includes ending the recording session.

Abstract: A method and system for fleet management is described. Fleet management data for a target fleet of vehicles is received. A target vehicle vector that represents a target vehicle of the target fleet is generated based on the fleet management data. One or more similar vehicles are identified, from a plurality of reference vehicles, that are similar to the target vehicle using a distance metric between the target vehicle vector and a plurality of reference vehicle vectors. The plurality of reference vehicle vectors representing the plurality of reference vehicles. Vehicle characteristics of the target vehicle and the one or more similar vehicles are identified, where the vehicle characteristics affect vehicle efficiency of the target vehicle. The vehicle characteristics affecting vehicle efficiency of the target vehicle and corresponding vehicle characteristics of the one or more similar vehicles are displayed.

Abstract: A low cost, economical filtration system for removing chemical and microbial contaminants from a liquid is disclosed. The filtration system includes a filter having a body made of wood. The body may have a first surface and a second surface, the first or second surface including at least one slot or opening, which may be perpendicular to the direction of the orientation of the wood. The filter may be inscribed into a container or filter holding part to form a seal. In use, a liquid enters the filter on the first side through the at least one slot and may be filtered whilst passing through the wood to the at least one slot on the second surface for collection as a filtrate. A filtration system can comprise one or more containers integrating the wood filter and permit separation of contaminants from the liquid and isolation of purified liquid.

Abstract: Techniques are disclosed to use robotic system simulation to control a robotic system. In various embodiments, a communication indicating an action to be performed by a robotic element is received from a robotic control system. Performance of the action by the robotic element is simulated. A state tracking data is updated to reflect a virtual change to one or more state variables as a result of simulated performance of the action. Successful completion of the action by the robotic element is reported to the robotic control system.

Abstract: An apparatus comprises at least one processing device configured to register two or more source services, wherein registering a given source service comprises executing the given source service to identify inputs and outputs of the given source service, and to select a set of outputs from the registered source services for generating at least a portion of a user interface of an application in an application client, the selected set of outputs comprising at least first and second output from first and second ones of the registered source services. The processing device is also configured to determine an orchestration of the registered source services for obtaining the selected set of outputs, to generate a custom microservice configured to execute the registered source services in accordance with the determined orchestration, and to deploy the custom microservice in an auto-scalable computing framework accessible to the application client of the application.

Abstract: An exemplary method of imaging tissue of a subject using a rolling shutter imager to provide a video stream comprises: sequentially resetting a plurality of rows of pixels of the rolling shutter imager from a first row to a last row; transitioning a liquid crystal shutter from a closed state to an open state; after the liquid crystal shutter is transitioned into the open state and after resetting the last row, illuminating the tissue of the subject with an illumination light for an illumination period to accumulate charge at the plurality of rows of pixels, and after the illumination period ends, sequentially reading the accumulated charge at the rows of pixels from the first row to the last row; generating an image frame from the sequentially read accumulated charge at the plurality of rows of pixels; and adding the image frame to the video stream.

Abstract: Disclosed herein are system, method, and computer program product embodiments for vaultless tokenization. Alphanumeric values may be determined based on numeric values generated from a hash of numeric user information shuffled through a plurality of randomly generated alphanumeric tables. The numeric user information and the alphanumeric values may be used to generate a table index. Shuffled numeric user information may be generated based on the table index and a plurality of randomly generated numeric tables, and transformed to alphanumeric user information (e.g., via format-preserving encryption, additive cipher, etc.). Each character of the alphanumeric user information may be shuffled through a different alphanumeric table of the plurality of alphanumeric tables identified for the character based on the table index. Moreover, an alphanumeric token may be generated based on the shuffled characters of the alphanumeric user information.

Abstract: Embodiments described herein relate to wireless communications, including methods and apparatus for dynamically selecting subscriber identity module (SIM) profiles, electronic SIM (eSIM) profiles, multi-SIM operating modes, and/or wireless access networks for network slice based applications of wireless devices. A wireless device can include at least two SIM/eSIM profiles and switch use of SIM/eSIM profiles, change between dual SIM operating modes, and/or select a registration mode based on requirements of one or more applications in use and availability of network slices via different wireless networks.

Abstract: In one aspect, a method includes receiving, a serving gateway of a core network of a wireless communication system, a call request associated with an emergency service; assigning a Tunnel Endpoint Identifier (TEID) to the call, wherein the TEID has a plurality of bits and a first segment of the plurality of bits are set to identify the TEID as being associated with the emergency service; and establishing the call for the emergency service with a Packet Data Gateway (PGW) of the core network using the TEID, wherein the TEID enables the PGW to suppress deletion of a bearer associated with the call.