Patents by Inventor Ron Weiss

Ron Weiss has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140186432
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
    Type: Application
    Filed: December 12, 2013
    Publication date: July 3, 2014
    Applicant: MODERNA THERAPEUTICS, INC.
    Inventors: Stephane Bancel, Tirtha Chakraborty, Antonin de Fougerolles, Susan Whoriskey, Ron Weiss
  • Publication number: 20140171485
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
    Type: Application
    Filed: December 13, 2013
    Publication date: June 19, 2014
    Applicant: MODERNA THERAPEUTICS, INC.
    Inventors: Stephane Bancel, Tirtha Chakraborty, Antonin de Fougerolles, Susan Whoriskey, Ron Weiss
  • Publication number: 20140161873
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
    Type: Application
    Filed: December 16, 2013
    Publication date: June 12, 2014
    Applicant: MODERNA THERAPEUTICS, INC.
    Inventors: Stephane Bancel, Tirtha Chakraborty, Antonin de Fougerolles, Susan Whoriskey, Ron Weiss
  • Publication number: 20140148589
    Abstract: Aspects herein relate to composition, and related methods, for isolating and assembling DNA molecules without intermediate cloning steps.
    Type: Application
    Filed: September 23, 2011
    Publication date: May 29, 2014
    Inventors: Jonathan William Babb, Shuo Cory Li, Thomas Knight, Ron Weiss
  • Publication number: 20140141067
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of oncology-related polynucleotides, oncology-related primary transcripts and oncology-related mmRNA molecules.
    Type: Application
    Filed: December 16, 2013
    Publication date: May 22, 2014
    Applicant: MODERNA THERAPEUTICS, INC.
    Inventors: Stephane Bancel, Tirtha Chakraborty, Antonin de Fougerolles, Susan Whoriskey, Ron Weiss
  • Publication number: 20140141068
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of oncology-related polynucleotides, oncology-related primary transcripts and oncology-related mmRNA molecules.
    Type: Application
    Filed: December 16, 2013
    Publication date: May 22, 2014
    Applicant: MODERNA THERAPEUTICS, INC.
    Inventors: Stephane Bancel, Tirtha Chakraborty, Antonin de Fougerolles, Susan Whoriskey, Ron Weiss
  • Publication number: 20140113959
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of oncology-related polynucleotides, oncology-related primary transcripts and oncology-related mmRNA molecules.
    Type: Application
    Filed: December 16, 2013
    Publication date: April 24, 2014
    Applicant: MODERNA THERAPEUTICS, INC.
    Inventors: Stephane Bancel, Tirtha Chakraborty, Antonin de Fougerolles, Susan Whoriskey, Ron Weiss
  • Publication number: 20140113960
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of oncology-related polynucleotides, oncology-related primary transcripts and oncology-related mmRNA molecules.
    Type: Application
    Filed: December 16, 2013
    Publication date: April 24, 2014
    Applicant: MODERNA THERAPEUTICS, INC.
    Inventors: Stephane Bancel, Tirtha Chakraborty, Antonin de Fougerolles, Susan Whoriskey, Ron Weiss
  • Publication number: 20140105964
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
    Type: Application
    Filed: December 11, 2013
    Publication date: April 17, 2014
    Applicant: MODERNA THERAPEUTICS, INC.
    Inventors: Stephane Bancel, Tirtha Chakraborty, Antonin de Fougerolles, Susan Whoriskey, Ron Weiss
  • Publication number: 20140107189
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of oncology-related polynucleotides, oncology-related primary transcripts and oncology-related mmRNA molecules.
    Type: Application
    Filed: December 16, 2013
    Publication date: April 17, 2014
    Applicant: MODERNA THERAPEUTICS, INC.
    Inventors: Stephane Bancel, Tirtha Chakraborty, Antonin de Fougerolles, Susan Whoriskey, Ron Weiss
  • Publication number: 20140105965
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
    Type: Application
    Filed: December 12, 2013
    Publication date: April 17, 2014
    Applicant: MODERNA THERAPEUTICS, INC.
    Inventors: Stephane Bancel, Tirtha Chakraborty, Antonin de Fougerolles, Susan Whoriskey, Ron Weiss
  • Publication number: 20140105966
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
    Type: Application
    Filed: December 13, 2013
    Publication date: April 17, 2014
    Applicant: MODERNA THERAPEUTICS, INC.
    Inventors: Stephane Bancel, Tirtha Chakraborty, Antonin de Fougerolles, Susan Whoriskey, Ron Weiss
  • Patent number: 8685720
    Abstract: The present invention provides compositions and methods for programming mammalian cells to perform desired functions. In particular, the present invention provides compositions and methods for programming stem cells to differentiate into a desired cell type. A quorum sensing systems that regulates the expression of cell fate regulators is introduced into mammalian host cells, such as stem cells. The quorum sensing systems generally comprises vectors that express the components of a bacterial quorum sensing pathway, including proteins which catalyze the synthesis of an autoinducer and a gene encoding a regulatory partner of the autoinducer, and vectors in which genes encoding cell fate regulators are operably linked to a promoter induced by the autoinducer/regulatory partner complex.
    Type: Grant
    Filed: November 1, 2007
    Date of Patent: April 1, 2014
    Assignee: The Trustees of Princeton University
    Inventors: Ron Weiss, Ihor Lemischka, Priscilla E. M. Purnick, Christoph Schaniel, Miles Miller, Patrick Guye
  • Publication number: 20140074269
    Abstract: Methods, systems, and computer programs are presented for recommending music entities to a user. One method includes defining a set of labels with each label identifying a music concept and constructing at least vector for each of a plurality of entities based on source data. Each vector includes the set of define labels and each label is assigned with a label score. Two vectors respectively associated with two of the plurality of entities are compared. The method further includes generating a recommendation action based on comparison result of the two vectors and transmitting the data for the recommendation action to a device of the user. In one example, the comparisons can be pre-computed and used for the recommendation action.
    Type: Application
    Filed: September 11, 2012
    Publication date: March 13, 2014
    Applicant: GOOGLE INC.
    Inventors: Jason Weston, Adam Berenzweig, Ron Weiss
  • Publication number: 20130325846
    Abstract: A method, computer program product, and computer system for latent collaborative retrieval are described. A first mathematical representation of a query received from a user is generated. A second mathematical representation of a user profile is generated. A plurality of mathematical representations associated with a plurality of items is accessed. The first mathematical representation, the second mathematical representation, and the plurality of mathematical representations are transformed to have a uniform length. A first results subset of items is generated, based upon, at least in part, a first similarity measurement of the first mathematical representation and the plurality of mathematical representations. A second result subset of items is generated based upon, at least in part, a second similarity measurement of the second mathematical representation and the plurality of mathematical representations. A result set of items is generated based upon, at least in part, the first and second result subsets.
    Type: Application
    Filed: June 1, 2012
    Publication date: December 5, 2013
    Applicant: Google Inc.
    Inventors: JASON WESTON, Ron Weiss, Adam Berenzweig, Chong Wang
  • Publication number: 20130202532
    Abstract: Provided herein are high-input detector modules and multi-input biological classifier circuits and systems that integrate sophisticated sensing, information processing, and actuation in living cells and permit new directions in basic biology, biotechnology and medicine. The multi-input biological classifier circuits described herein comprise synthetic, scaleable transcriptional/post-transcriptional regulatory circuits that are designed to interrogate the status of a cell by simultaneously sensing expression levels of multiple endogenous inputs, such as microRNAs. The classifier circuits then compute whether to trigger a desired output or response if the expression levels match a pre-determined profile of interest.
    Type: Application
    Filed: July 22, 2011
    Publication date: August 8, 2013
    Applicants: MASSACHUSETTS INSTITUTE OF TECHNOLOGY, PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Yaakov Benenson, Ron Weiss, Liliana Wroblewska, Zhen Xie
  • Publication number: 20130171626
    Abstract: Described herein are methods of evaluating the expression levels of DNA parts encoding proteins in test circuits. In particular, the methods disclosed herein are useful to evaluate the expression of an output protein regulated by a regulatory protein-genetic element pair.
    Type: Application
    Filed: January 4, 2012
    Publication date: July 4, 2013
    Applicants: MASSACHUSETTS INSTITUTE OF TECHNOLOGY, RAYTHEON BBN TECHNOLOGIES CORP.
    Inventors: Aaron Daniel Adler, Jacob Stuart Michael Beal, Fusun Yaman-Sirin, Ron Weiss, Noah Justin Davidsohn
  • Publication number: 20120027786
    Abstract: Aspects of the invention relate to compositions and methods for using recombinant cells to sense and destroy specific pathogens.
    Type: Application
    Filed: February 23, 2011
    Publication date: February 2, 2012
    Applicant: Massachusetts Institute of Technology
    Inventors: Saurabh Gupta, Ron Weiss
  • Publication number: 20110257041
    Abstract: Aspects of the invention relate to reconfigurable chassis that allow for rapid construction and optimization of biocircuits.
    Type: Application
    Filed: November 15, 2010
    Publication date: October 20, 2011
    Applicant: Massachusetts Institute of Technology
    Inventors: Jonathan William Babb, Ron Weiss, Thomas Knight, Adam Rubin
  • Publication number: 20110237652
    Abstract: In its various embodiments, the invention provides, first, a composition comprising a vector for transfecting a cell. The vector comprises a first nucleic acid encoding an antisense agent having thereon an RNA interference target for a transcript of a gene endogenous to the cell. The vector further comprises a second nucleic acid that encodes a cell-killing agent. The second nucleic acid further comprises a sequence of nucleotides transcribable into a non-coding region of a transcript of the second nucleic acid, such that the non-coding region becomes an RNA interference target for the antisense agent. In the transfected cell, the vector operates to interfere with the expression of the cell-killing agent unless and until the vector senses certain endogenous gene signals, whereupon it releases the cell-killing agent.
    Type: Application
    Filed: October 15, 2009
    Publication date: September 29, 2011
    Inventors: Ron WEISS, Priscilla E. M. PURNICK, Caroline DEHART, Jon MONK, Aparna SWAMINATHAN